Gunnar Norstedt

Iglesias-Gato D; Chuan Y-C; Wikström P; Augsten S; Jiang N; Niu Y; Seipel A; Danneman D; Vermeij M; Fernandez-Perez L; Jenster G; Egevad L; Norstedt G; Flores-Morales A

Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2013;172(3):490-499

The effects of chemotherapeutic drugs on human monocyte-derived dendritic cell differentiation and antigen presentation.

Hu J; Kinn J; Zirakzadeh AA; Sherif A; Norstedt G; Wikström A-C; Winqvist O

Article: CLINICAL ENDOCRINOLOGY. 2012;77(2):288-295

Effects of oestrogen and testosterone therapy on serum metabolites in postmenopausal women.

Zang H; Moritz T; Norstedt G; Hirschberg AL; Tollet-Egnell P

Article: FASEB JOURNAL. 2012;26(8):3282-3291

SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice.

Zadjali F; Santana-Farre R; Vesterlund M; Carow B; Mirecki-Garrido M; Hernandez-Hernandez I; Flodström-Tullberg M; Parini P; Rottenberg M; Norstedt G; Fernandez-Perez L; Flores-Morales A

Article: PHYTOTHERAPY RESEARCH. 2012;26(2):259-264

Androgen-independent effects of Serenoa repens extract (Prostasan®) on prostatic epithelial cell proliferation and inflammation.

Iglesias-Gato D; Carsten T; Vesterlund M; Pousette A; Schoop R; Norstedt G

Article: PLOS ONE. 2012;7(1):e30166

LPS regulates SOCS2 transcription in a type I interferon dependent autocrine-paracrine loop.

Hu J; Lou D; Carow B; Winerdal ME; Rottenberg M; Wikström A-C; Norstedt G; Winqvist O

Article: PLOS ONE. 2012;7(5):e37386

Influence of neonatal hypothyroidism on hepatic gene expression and lipid metabolism in adulthood.

Santana-Farré R; Mirecki-Garrido M; Bocos C; Henríquez-Hernández LA; Kahlon N; Herrera E; Norstedt G; Parini P; Flores-Morales A; Fernández-Pérez L

Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2011;127(3-5):269-275

Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells.

Iglesias-Gato D; Zheng S; Flanagan JN; Jiang L; Kittaka A; Sakaki T; Yamamoto K; Itoh T; Lebrasseur NK; Norstedt G; Chen TC

Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2011;47(2):129-143

Sex-dependent hepatic transcripts and metabolites in the development of glucose intolerance and insulin resistance in Zucker diabetic fatty rats.

Gustavsson C; Soga T; Wahlström E; Vesterlund M; Azimi A; Norstedt G; Tollet-Egnell P

Article: PLOS ONE. 2011;6(9):e25358

The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels.

Vesterlund M; Zadjali F; Persson T; Nielsen ML; Kessler BM; Norstedt G; Flores-Morales A

Article: BMC BIOCHEMISTRY. 2010;11:38

Sex-different hepaticglycogen content and glucose output in rats.

Gustavsson C; Yassin K; Wahlström E; Cheung L; Lindberg J; Brismar K; Ostenson C-G; Norstedt G; Tollet-Egnell P

Article: CLINICAL ENDOCRINOLOGY. 2010;72(6):800-806

The effect of in vivo growth hormone treatment on blood gene expression in adults with growth hormone deficiency reveals potential biomarkers to monitor growth hormone therapy.

Fernández-Pérez L; Nóvoa J; Ståhlberg N; Santana-Farré R; Boronat M; Marrero D; Henríquez-Hernández L; Norstedt G; Flores-Morales A

Article: ONCOGENE. 2010;29(10):1531-1542

Ezrin mediates c-Myc actions in prostate cancer cell invasion.

Chuan Y-C; Iglesias-Gato D; Fernandez-Perez L; Cedazo-Minguez A; Pang S-T; Norstedt G; Pousette A; Flores-Morales A

Article: LIPIDS. 2009;44(11):1011-1027

Cocoa butter and safflower oil elicit different effects on hepatic gene expression and lipid metabolism in rats.

Gustavsson C; Parini P; Ostojic J; Cheung L; Hu J; Zadjali F; Tahir F; Brismar K; Norstedt G; Tollet-Egnell P

Article: PLOS ONE. 2009;4(9):e7178

SOCS2 influences LPS induced human monocyte-derived dendritic cell maturation.

Hu J; Winqvist O; Flores-Morales A; Wikström A-C; Norstedt G

Article: BMC MOLECULAR BIOLOGY. 2009;10:13

Sex-different and growth hormone-regulated expression of microRNA in rat liver.

Cheung L; Gustavsson C; Norstedt G; Tollet-Egnell P

Article: METABOLOMICS. 2008;4(3):273-282

Metabolomics as a tool to evaluate exercise-induced improvements in insulin sensitivity

Kuhl J; Moritz T; Wagner H; Stenlund H; Lundgren K; Bavenholm P; Efendic S; Norstedt G; Tollet-Egnell P

Article: NUCLEIC ACIDS RESEARCH. 2008;36(9):e53

Analysis of siRNA specificity on targets with double-nucleotide mismatches.

Dahlgren C; Zhang H-Y; Du Q; Grahn M; Norstedt G; Wahlestedt C; Liang Z

Article: MUSCLE & NERVE. 2007;36(2):223-233

Iron load and redox stress in skeletal muscle of aged rats.

Altun M; Edström E; Spooner E; Flores-Moralez A; Bergman E; Tollet-Egnell P; Norstedt G; Kessler BM; Ulfhake B

Article: BMC MOLECULAR BIOLOGY. 2007;8:60

Hormonal and nutritional regulation of alternative CD36 transcripts in rat liver--a role for growth hormone in alternative exon usage.

Cheung L; Andersen M; Gustavsson C; Odeberg J; Fernández-Pérez L; Norstedt G; Tollet-Egnell P

Article: PLOS ONE. 2007;2(7):e610

MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?

Sonkoly E; Wei T; Janson PCJ; Sääf A; Lundeberg L; Tengvall-Linder M; Norstedt G; Alenius H; Homey B; Scheynius A; Ståhle M; Pivarcsi A

Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2007;320(2):695-705

Role of pituitary hormones on 17alpha-ethinylestradiol-induced cholestasis in rat.

Henríquez-Hernández LA; Flores-Morales A; Santana-Farré R; Axelson M; Nilsson P; Norstedt G; Fernández-Pérez L

Article: MOLECULAR ENDOCRINOLOGY. 2007;21(1):293-311

In vivo transcript profiling and phylogenetic analysis identifies suppressor of cytokine signaling 2 as a direct signal transducer and activator of transcription 5b target in liver.

Vidal OM; Merino R; Rico-Bautista E; Fernandez-Perez L; Chia DJ; Woelfle J; Ono M; Lenhard B; Norstedt G; Rotwein P; Flores-Morales A

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(40):29938-29948

Androgen induction of prostate cancer cell invasion is mediated by ezrin.

Chuan Y-C; Pang S-T; Cedazo-Minguez A; Norstedt G; Pousette A; Flores-Morales A

Article: PROSTATE. 2006;66(12):1235-1244

Proteomic comparison of prostate cancer cell lines LNCaP-FGC and LNCaP-r reveals heatshock protein 60 as a marker for prostate malignancy.

Johansson B; Pourian MR; Chuan Y-C; Byman I; Bergh A; Pang S-T; Norstedt G; Bergman T; Pousette A

Article: PROSTATE. 2006;66(2):157-172

Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer.

Pang S-T; Weng W-H; Flores-Morales A; Johansson B; Pourian MR; Nilsson P; Pousette A; Larsson C; Norstedt G

Article: INTERNATIONAL JOURNAL OF ANDROLOGY. 2005;28(5):291-296

Androgens induce CD-9 in human prostate tissue.

Chuan Y; Pang S-T; Bergh A; Norstedt G; Pousette A

Article: MOLECULAR ENDOCRINOLOGY. 2005;19(3):781-793

Suppressor of cytokine signaling-2 deficiency induces molecular and metabolic changes that partially overlap with growth hormone-dependent effects.

Rico-Bautista E; Greenhalgh CJ; Tollet-Egnell P; Hilton DJ; Alexander WS; Norstedt G; Flores-Morales A

Article: JOURNAL OF CLINICAL INVESTIGATION. 2005;115(2):397-406

SOCS2 negatively regulates growth hormone action in vitro and in vivo.

Greenhalgh CJ; Rico-Bautista E; Lorentzon M; Thaus AL; Morgan PO; Willson TA; Zervoudakis P; Metcalf D; Street I; Nicola NA; Nash AD; Fabri LJ; Norstedt G; Ohlsson C; Flores-Morales A; Alexander WS; Hilton DJ

Article: ONCOLOGY REPORTS. 2004;11(6):1187-1192

Regulation of matrix metalloproteinase 13 expression by androgen in prostate cancer.

Pang S-T; Flores-Morales A; Skoog L; Chuan Y-C; Nordstedt G; Pousette A

Article: ENDOCRINOLOGY. 2004;145(4):1972-1979

Female-predominant expression of fatty acid translocase/CD36 in rat and human liver.

Ståhlberg N; Rico-Bautista E; Fisher RM; Wu X; Cheung L; Flores-Morales A; Tybring G; Norstedt G; Tollet-Egnell P

Article: UROLOGY. 2004;63(3):609-612

Expression of ezrin in prostatic intraepithelial neoplasia.

Pang S-T; Fang X; Valdman A; Norstedt G; Pousette A; Egevad L; Ekman P

Article: PHYSIOLOGICAL GENOMICS. 2004;16(2):261-267

Growth hormone-mediated alteration of fuel metabolism in the aged rat as determined from transcript profiles.

Tollet-Egnell P; Parini P; Ståhlberg N; Lönnstedt I; Lee NH; Rudling M; Flores-Morales A; Norstedt G

Article: JOURNAL OF LIPID RESEARCH. 2004;45(1):148-154

Differentially expressed genes in visceral or subcutaneous adipose tissue of obese men and women.

Linder K; Arner P; Flores-Morales A; Tollet-Egnell P; Norstedt G

Article: ENDOCRINOLOGY. 2003;144(11):4955-4966

Gene expression analysis of prostate hyperplasia in mice overexpressing the prolactin gene specifically in the prostate.

Dillner K; Kindblom J; Flores-Morales A; Shao R; Törnell J; Norstedt G; Wennbo H

Article: BIOLOGY OF REPRODUCTION. 2003;69(4):1308-1317

Gene expression profiling of the effects of castration and estrogen treatment in the rat uterus.

Wu X; Pang S-T; Sahlin L; Blanck A; Norstedt G; Flores-Morales A

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(38):35988-35999

Development of pure prolactin receptor antagonists.

Bernichtein S; Kayser C; Dillner K; Moulin S; Kopchick JJ; Martial JA; Norstedt G; Isaksson O; Kelly PA; Goffin V

Article: INTERNATIONAL JOURNAL OF CANCER. 2003;104(2):131-138

Differentially expressed transcripts in neoplastic hepatic nodules and neonatal rat liver studied by cDNA microarray analysis.

Tellgren A; Wood TJJ; Flores-Morales A; Torndal U-B; Eriksson L; Norstedt G

Article: ENDOCRINOLOGY. 2002;143(12):4897-4906

Gene expression profiling of androgen deficiency predicts a pathway of prostate apoptosis that involves genes related to oxidative stress.

Pang S-T; Dillner K; Wu X; Pousette A; Norstedt G; Flores-Morales A

Article: PROSTATE. 2002;52(2):139-149

Molecular characterization of prostate hyperplasia in prolactin-transgenic mice by using cDNA representational difference analysis.

Dillner K; Kindblom J; Flores-Morales A; Pang S-T; Törnell J; Wennbo H; Norstedt G

Article: MOLECULAR ENDOCRINOLOGY. 2002;16(6):1257-1268

Patterns of liver gene expression governed by TRbeta.

Flores-Morales A; Gullberg H; Fernandez L; Ståhlberg N; Lee NH; Vennström B; Norstedt G

Article: MOLECULAR HUMAN REPRODUCTION. 2002;8(3):246-254

Identification of genes with higher expression in human uterine leiomyomas than in the corresponding myometrium.

Wu X; Blanck A; Norstedt G; Sahlin L; Flores-Morales A

Article: MOLECULAR ENDOCRINOLOGY. 2001;15(9):1471-1483

Endoplasmic reticulum stress prolongs GH-induced Janus kinase (JAK2)/signal transducer and activator of transcription (STAT5) signaling pathway.

Flores-Morales A; Fernández L; Rico-Bautista E; Umana A; Negrín C; Zhang JG; Norstedt G

Article: ENDOCRINOLOGY. 2001;142(7):3163-3176

Microarray analysis of the in vivo effects of hypophysectomy and growth hormone treatment on gene expression in the rat.

Flores-Morales A; Ståhlberg N; Tollet-Egnell P; Lundeberg J; Malek RL; Quackenbush J; Lee NH; Norstedt G

Article: MOLECULAR ENDOCRINOLOGY. 2001;15(2):308-318

Gene expression profile of the aging process in rat liver: normalizing effects of growth hormone replacement.

Tollet-Egnell P; Flores-Morales A; Ståhlberg N; Malek RL; Lee N; Norstedt G

Article: NEW BIOTECHNOLOGY. 2000;17(1):1-9

A cDNA RDA protocol using solid-phase technology suited for analysis in small tissue samples.

Odeberg J; Wood T; Blücher A; Rafter J; Norstedt G; Lundeberg J

Article: GROWTH HORMONE & IGF RESEARCH. 2000;10(5):236-241

Comparison of STAT5 mRNA levels in GH-treated male and female rats analysed by a solution hybridization assay.

Ortiz BL; Sánchez-Gómez M; Norstedt G

Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2000;143(1):71-76

Characterisation of novel missense mutations in the GH receptor gene causing severe growth retardation.

Enberg B; Luthman H; Segnestam K; Ritzén EM; Sundström M; Norstedt G

Article: ENDOCRINOLOGY. 2000;141(3):910-921

Differential cloning of growth hormone-regulated hepatic transcripts in the aged rat.

Tollet-Egnell P; Flores-Morales A; Odeberg J; Lundeberg J; Norstedt G

Article: ENDOCRINOLOGY. 1999;140(8):3693-3704

Growth hormone regulation of SOCS-2, SOCS-3, and CIS messenger ribonucleic acid expression in the rat.

Tollet-Egnell P; Flores-Morales A; Stavréus-Evers A; Sahlin L; Norstedt G

Article: ENDOCRINOLOGY. 1998;139(4):1815-1824

Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C.

Fernández L; Flores-Morales A; Lahuna O; Sliva D; Norstedt G; Haldosén LA; Mode A; Gustafsson JA

Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1998;138(1-2):1-10

In vitro interaction between STAT 5 and JAK 2; dependence upon phosphorylation status of STAT 5 and JAK 2.

Flores-Morales A; Pircher TJ; Silvennoinen O; Gustafsson JA; Sanchez-Gomez M; Norstedt G; Haldosén LA; Wood TJ

Article: ACTA ORTHOPAEDICA. 1997;68(6):586-592

Insulin-like growth factor I increases bone formation in old or corticosteroid treated rats.

Prisell PT; Aspenberg P; Wikström B; Wredmark T; Norstedt G

Article: EXPERIMENTAL CELL RESEARCH. 1997;237(1):196-206

Mode of the autocrine/paracrine mechanism of growth hormone action.

Liu N; Mertani HC; Norstedt G; Törnell J; Lobie PE

Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1997;133(2):169-176

Mitogen-activated protein kinase kinase inhibition decreases growth hormone stimulated transcription mediated by STAT5.

Pircher TJ; Flores-Morales A; Mui AL; Saltiel AR; Norstedt G; Gustafsson JA; Haldosén LA

Article: ENDOCRINOLOGY. 1997;138(8):3207-3215

Growth hormone-induced reorganization of the actin cytoskeleton is not required for STAT5 (signal transducer and activator of transcription-5)-mediated transcription.

Goh EL; Pircher TJ; Wood TJ; Norstedt G; Graichen R; Lobie PE

Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1997;130(1-2):69-81

Specificity of transcription enhancement via the STAT responsive element in the serine protease inhibitor 2.1 promoter.

Wood TJ; Sliva D; Lobie PE; Goullieux F; Mui AL; Groner B; Norstedt G; Haldosén LA

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(50):32197-32203

Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution.

Sundström M; Lundqvist T; Rödin J; Giebel LB; Milligan D; Norstedt G

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(46):29415-29421

Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling.

Argetsinger LS; Norstedt G; Billestrup N; White MF; Carter-Su C

Article: ENDOCRINOLOGY. 1996;137(9):4037-4045

Constitutive nuclear localization of Janus kinases 1 and 2.

Lobie PE; Ronsin B; Silvennoinen O; Haldosén LA; Norstedt G; Morel G

Article: MOLECULAR ENDOCRINOLOGY. 1996;10(5):519-533

The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.

Smit LS; Meyer DJ; Billestrup N; Norstedt G; Schwartz J; Carter-Su C

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(37):21745-21750

Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function.

Lobie PE; Allevato G; Nielsen JH; Norstedt G; Billestrup N

Article: ENDOCRINOLOGY. 1995;136(9):3767-3773

Growth hormone specifically stimulates the expression of low density lipoprotein receptors in human hepatoma cells.

Parini P; Angelin B; Lobie PE; Norstedt G; Rudling M

Article: PEDIATRIC RESEARCH. 1995;38(3):418-421

Growth hormone (GH) treatment up-regulates GH receptor mRNA levels in adipocytes from patients with GH deficiency and Prader-Willi syndrome.

Kamel A; Margery V; Norstedt G; Thorén M; Lindgren AC; Brönnegård M; Marcus C

Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1995;113(1):11-17

Hormonal regulation of the female enriched GH receptor/binding protein mRNA in rat liver.

Ahlgren R; Norstedt G; Baumbach WR; Mode A

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(29):17210-17214

Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation.

Allevato G; Billestrup N; Goujon L; Galsgaard ED; Norstedt G; Postel-Vinay MC; Kelly PA; Nielsen JH

Article: EMBO JOURNAL. 1995;14(9):2005-2013

Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-Stat5 DNA binding activity.

Gouilleux F; Pallard C; Dusanter-Fourt I; Wakao H; Haldosen LA; Norstedt G; Levy D; Groner B

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(16):9448-9453

Mediation of growth hormone-dependent transcriptional activation by mammary gland factor/Stat 5.

Wood TJ; Sliva D; Lobie PE; Pircher TJ; Gouilleux F; Wakao H; Gustafsson JA; Groner B; Norstedt G; Haldosén LA

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(13):7587-7593

Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2.

VanderKuur J; Allevato G; Billestrup N; Norstedt G; Carter-Su C

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