This page in English

Göran K Hansson

Professor

Telefon

08-524 878 01

E-post

Goran.Hansson@ki.se

Organisatorisk tillhörighet

Forskargrupp G Hansson

Institution

Institutionen för medicin, Solna (MedS), K2

Besöksadress : Cmm, L8:03, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm
Postadress : Institutionen för medicin, Solna (MedS), K2, Forskargrupp G Hansson, Cmm, L8:03, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm
Leveransadress : Cmm, L8:03, Karolinska Universitetssjukhuset, Solna 171 76 Stockholm

Publikationer

Anti-inflammatory therapies for atherosclerosis
Back M, Hansson Gk
Nature reviews. Cardiology 2015;12(4):199-211

At its heart, homeostasis is about T cells
Hansson Gk
Journal of the American College of Cardiology 2015;65(12):1187-9

How to repeat a success and control a bad influence
Hansson Gk
Circulation 2015;131(6):525-7

Inflammation and immunity in diseases of the arterial tree: players and layers
Libby P, Hansson Gk
Circulation research 2015;116(2):307-11

Inhibition of indoleamine 2,3-dioxygenase promotes vascular inflammation and increases atherosclerosis in Apoe-/- mice
Polyzos Ka, Ovchinnikova O, Berg M, Baumgartner R, Agardh H, Pirault J, et al
Cardiovascular research 2015;106(2):295-302

Modulation of autoimmunity and atherosclerosis - common targets and promising translational approaches against disease
Ketelhuth Df, Hansson Gk
Circulation journal : official journal of the Japanese Circulation Society 2015;79(5):924-33

Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response
Grasset Ek, Duhlin A, Agardh He, Ovchinnikova O, Hagglof T, Forsell Mn, et al
Proceedings of the National Academy of Sciences of the United States of America 2015;112(16):E2030-8

The role of the FPR2/ALX receptor in atherosclerosis development and plaque stability
Petri Mh, Laguna-fernandez A, Gonzalez-diez M, Paulsson-berne G, Hansson Gk, Back M
Cardiovascular research 2015;105(1):65-74

?7 Nicotinic acetylcholine receptor is expressed in human atherosclerosis and inhibits disease in mice--brief report
Johansson Me, Ulleryd Ma, Bernardi A, Lundberg Am, Andersson A, Folkersen L, et al
Arteriosclerosis, thrombosis, and vascular biology 2014;34(12):2632-6

A journey in science: medical scientist in translation
Hansson Gk
Molecular medicine (Cambridge, Mass.) 2014;20():381-9

Apolipoprotein B100 danger-associated signal 1 (ApoBDS-1) triggers platelet activation and boosts platelet-leukocyte proinflammatory responses
Assinger A, Wang Y, Butler Lm, Hansson Gk, Yan Zq, Soderberg-naucler C, et al
Thrombosis and haemostasis 2014;112(2):332-41

Human genetic evidence for involvement of CD137 in atherosclerosis
Soderstrom La, Gertow K, Folkersen L, Sabater-lleal M, Sundman E, Sheikine Y, et al
Molecular medicine (Cambridge, Mass.) 2014;20():456-65

Innate immune receptor NOD2 promotes vascular inflammation and formation of lipid-rich necrotic cores in hypercholesterolemic mice
Johansson Me, Zhang Xy, Edfeldt K, Lundberg Am, Levin Mc, Boren J, et al
European journal of immunology 2014;44(10):3081-92

MHC Class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity
Sage Ap, Murphy D, Maffia P, Masters Lm, Sabir Sr, Baker Ll, et al
Circulation 2014;130(16):1363-73

Mycobacterium bovis BCG killed by extended freeze-drying induces an immunoregulatory profile and protects against atherosclerosis
Ovchinnikova Oa, Berge N, Kang C, Urien C, Ketelhuth Df, Pottier J, et al
Journal of internal medicine 2014;275(1):49-58

Platelets provoke distinct dynamics of immune responses by differentially regulating CD4+ T-cell proliferation
Zhu L, Huang Z, Stalesen R, Hansson Gk, Li N
Journal of thrombosis and haemostasis : JTH 2014;12(7):1156-65

The collagen cross-linking enzyme lysyl oxidase is associated with the healing of human atherosclerotic lesions
Ovchinnikova Oa, Folkersen L, Persson J, Lindeman Jh, Ueland T, Aukrust P, et al
Journal of internal medicine 2014;276(5):525-36

CARD8 gene encoding a protein of innate immunity is expressed in human atherosclerosis and associated with markers of inflammation
Paramel Gv, Folkersen L, Strawbridge Rj, Elmabsout Aa, Sarndahl E, Lundman P, et al
Clinical science (London, England : 1979) 2013;125(8):401-7

Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis
Klingenberg R, Gerdes N, Badeau Rm, Gistera A, Strodthoff D, Ketelhuth Df, et al
The Journal of clinical investigation 2013;123(3):1323-34

Fatty acid binding protein 4 in circulating leucocytes reflects atherosclerotic lesion progression in Apoe(-/-) mice
Agardh He, Gertow K, Salvado Dm, Hermansson A, Van Puijvelde Gh, Hansson Gk, et al
Journal of cellular and molecular medicine 2013;17(2):303-10

Immune effector mechanisms implicated in atherosclerosis: from mice to humans
Libby P, Lichtman Ah, Hansson Gk
Immunity 2013;38(6):1092-104

Lack of invariant natural killer T cells affects lipid metabolism in adipose tissue of diet-induced obese mice
Strodthoff D, Lundberg Am, Agardh He, Ketelhuth Df, Paulsson-berne G, Arner P, et al
Arteriosclerosis, thrombosis, and vascular biology 2013;33(6):1189-96

NOD2-mediated innate immune signaling regulates the eicosanoids in atherosclerosis
Liu Hq, Zhang Xy, Edfeldt K, Nijhuis Mo, Idborg H, Back M, et al
Arteriosclerosis, thrombosis, and vascular biology 2013;33(9):2193-201

T cell-based therapies for atherosclerosis
Ketelhuth Df, Gistera A, Johansson Dk, Hansson Gk
Current pharmaceutical design 2013;19(33):5850-8

Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis
Lundberg Am, Ketelhuth Df, Johansson Me, Gerdes N, Liu S, Yamamoto M, et al
Cardiovascular research 2013;99(2):364-73

Transforming growth factor-ss signaling in T cells promotes stabilization of atherosclerotic plaques through an interleukin-17-dependent pathway
Gistera A, Robertson Ak, Andersson J, Ketelhuth Df, Ovchinnikova O, Nilsson Sk, et al
Science translational medicine 2013;5(196):196ra100-

Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs
Subramanian M, Thorp E, Hansson Gk, Tabas I
The Journal of clinical investigation 2013;123(1):179-88

Valvular osteoclasts in calcification and aortic valve stenosis severity
Nagy E, Eriksson P, Yousry M, Caidahl K, Ingelsson E, Hansson Gk, et al
International journal of cardiology 2013;168(3):2264-71

Cysteinyl leukotriene signaling aggravates myocardial hypoxia in experimental atherosclerotic heart disease
Nobili E, Salvado Md, Folkersen L, Castiglioni L, Kastrup J, Wetterholm A, et al
PloS one 2012;7(7):e41786-

How to chew up cells: lessons for the atherosclerotic plaque
Hansson Gk
Circulation research 2012;111(6):669-71

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk
Gertow K, Sennblad B, Strawbridge Rj, Ohrvik J, Zabaneh D, Shah S, et al
Circulation. Cardiovascular genetics 2012;5(6):656-65

Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization
Smedbakken Lm, Halvorsen B, Daissormont I, Ranheim T, Michelsen Ae, Skjelland M, et al
Atherosclerosis 2012;224(1):266-73

Prediction of ischemic events on the basis of transcriptomic and genomic profiling in patients undergoing carotid endarterectomy
Folkersen L, Persson J, Ekstrand J, Agardh He, Hansson Gk, Gabrielsen A, et al
Molecular medicine (Cambridge, Mass.) 2012;18():669-75

Proatherogenic role of interleukin-18: effects on inflammation and action on vascular cells
Elhage R, Ljunggren Hg, Hansson Gk
CARDIOVASCULAR RESEARCH 2012;96(2):176-180

Subcutaneous immunization with heat shock protein-65 reduces atherosclerosis in Apoe?/? mice
Klingenberg R, Ketelhuth Df, Strodthoff D, Gregori S, Hansson Gk
Immunobiology 2012;217(5):540-7

The tryptophan metabolite 3-hydroxyanthranilic acid lowers plasma lipids and decreases atherosclerosis in hypercholesterolaemic mice
Zhang L, Ovchinnikova O, Jonsson A, Lundberg Am, Berg M, Hansson Gk, et al
European heart journal 2012;33(16):2025-34

Toll-like receptor 7 protects from atherosclerosis by constraining "inflammatory" macrophage activation
Salagianni M, Galani Ie, Lundberg Am, Davos Ch, Varela A, Gavriil A, et al
Circulation 2012;126(8):952-62

12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms
Gertow K, Nobili E, Folkersen L, Newman Jw, Pedersen Tl, Ekstrand J, et al
Atherosclerosis 2011;215(2):411-6

Cellular immunity, low-density lipoprotein and atherosclerosis: break of tolerance in the artery wall
Ketelhuth Df, Hansson Gk
Thrombosis and haemostasis 2011;106(5):779-86

Correlations between clinical variables and gene-expression profiles in carotid plaque instability
Razuvaev A, Ekstrand J, Folkersen L, Agardh H, Markus D, Swedenborg J, et al
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2011;42(6):722-30

Highlights of 10 years of immunology in Nature Reviews Immunology
Medzhitov R, Shevach Em, Trinchieri G, Mellor Al, Munn Dh, Gordon S, et al
Nature reviews. Immunology 2011;11(10):693-702

Identification of a danger-associated peptide from apolipoprotein B100 (ApoBDS-1) that triggers innate proatherogenic responses
Ketelhuth Df, Rios Fj, Wang Y, Liu H, Johansson Me, Fredrikson Gn, et al
Circulation 2011;124(22):2433-43

Immunotherapy with tolerogenic apolipoprotein B-100-loaded dendritic cells attenuates atherosclerosis in hypercholesterolemic mice
Hermansson A, Johansson Dk, Ketelhuth Df, Andersson J, Zhou X, Hansson Gk
Circulation 2011;123(10):1083-91

Personal Prizes for Cardiovascular Research: The Anitschkow Award 2007 Winner
Taylor J, Hansson Gk
CIRCULATION 2011;124(14):F84-F84

Platelets regulate CD4? T-cell differentiation via multiple chemokines in humans
Gerdes N, Zhu L, Ersoy M, Hermansson A, Hjemdahl P, Hu H, et al
Thrombosis and haemostasis 2011;106(2):353-62

Progress and challenges in translating the biology of atherosclerosis
Libby P, Ridker Pm, Hansson Gk
Nature 2011;473(7347):317-25

Pulling down the plug on atherosclerosis: cooling down the inflammasome
Hansson Gk, Klareskog L
Nature medicine 2011;17(7):790-1

Rip2 deficiency leads to increased atherosclerosis despite decreased inflammation
Levin Mc, Jirholt P, Wramstedt A, Johansson Me, Lundberg Am, Trajkovska Mg, et al
Circulation research 2011;109(11):1210-8

The immune system in atherosclerosis
Hansson Gk, Hermansson A
Nature immunology 2011;12(3):204-12

Toll in the vessel wall--for better or worse?
Hansson Gk, Lundberg Am
Proceedings of the National Academy of Sciences of the United States of America 2011;108(7):2637-8

Upregulation of the 5-lipoxygenase pathway in human aortic valves correlates with severity of stenosis and leads to leukotriene-induced effects on valvular myofibroblasts
Nagy E, Andersson Dc, Caidahl K, Eriksson Mj, Eriksson P, Franco-cereceda A, et al
Circulation 2011;123(12):1316-25

Activation of VPAC1 receptors aggravates early atherosclerosis in hypercholesterolemic apolipoprotein E-deficient mice
Sheikine Y, Deodato B, Olofsson Ps, Soderstrom La, Lundberg Am, Bodin I, et al
Biochemical and biophysical research communications 2010;402(3):471-6

Adaptive immunity and atherosclerosis
Andersson J, Libby P, Hansson Gk
Clinical immunology (Orlando, Fla.) 2010;134(1):33-46

Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease
Folkersen L, Van't Hooft F, Chernogubova E, Agardh He, Hansson Gk, Hedin U, et al
Circulation. Cardiovascular genetics 2010;3(4):365-73

Dendritic cells pulsed with malondialdehyde modified low density lipoprotein aggravate atherosclerosis in Apoe(-/-) mice
Hjerpe C, Johansson D, Hermansson A, Hansson Gk, Zhou X
Atherosclerosis 2010;209(2):436-41

Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis
Hermansson A, Ketelhuth Df, Strodthoff D, Wurm M, Hansson Em, Nicoletti A, et al
The Journal of experimental medicine 2010;207(5):1081-93

Innate immune signals in atherosclerosis
Lundberg Am, Hansson Gk
Clinical immunology (Orlando, Fla.) 2010;134(1):5-24

Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis
Klingenberg R, Lebens M, Hermansson A, Fredrikson Gn, Strodthoff D, Rudling M, et al
Arteriosclerosis, thrombosis, and vascular biology 2010;30(5):946-52

Raised MCP-4 levels in symptomatic carotid atherosclerosis: an inflammatory link between platelet and monocyte activation
Breland Um, Michelsen Ae, Skjelland M, Folkersen L, Krohg-sorensen K, Russell D, et al
Cardiovascular research 2010;86(2):265-73

Short-term delivery of anti-PlGF antibody delays progression of atherosclerotic plaques to vulnerable lesions
Roncal C, Buysschaert I, Gerdes N, Georgiadou M, Ovchinnikova O, Fischer C, et al
Cardiovascular research 2010;86(1):29-36

Medicine. Tackling two diseases with HDL
Hansson Gk, Bjorkholm M
Science (New York, N.Y.) 2010;328(5986):1641-2

The 5-lipoxygenase pathway inversely correlates with the preoperative non invasive haemodynamic parameters quantifying stenosis severity in human aortic valve stenosis
Nagy E, Caidahl K, Eriksson M, Franco-cereceda A, Hansson Gk, Back M
EUROPEAN HEART JOURNAL 2010;:962-962

The use of network analyses for elucidating mechanisms in cardiovascular disease
Diez D, Wheelock Am, Goto S, Haeggstrom Jz, Paulsson-berne G, Hansson Gk, et al
Molecular bioSystems 2010;6(2):289-304

Thromboxane synthase expression and thromboxane A2 production in the atherosclerotic lesion
Gabrielsen A, Qiu H, Back M, Hamberg M, Hemdahl Al, Agardh H, et al
Journal of molecular medicine (Berlin, Germany) 2010;88(8):795-806

Atherosclerosis--an immune disease: The Anitschkov Lecture 2007
Hansson Gk
Atherosclerosis 2009;202(1):2-10

Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis
Ueland T, Otterdal K, Lekva T, Halvorsen B, Gabrielsen A, Sandberg Wj, et al
Arteriosclerosis, thrombosis, and vascular biology 2009;29(8):1228-34

Genetic variants of TNFSF4 and risk for carotid artery disease and stroke
Olofsson Ps, Soderstrom La, Jern C, Sirsjo A, Ria M, Sundler E, et al
Journal of molecular medicine (Berlin, Germany) 2009;87(4):337-46

Hypercholesterolemia leads to elevated TGF-beta1 activity and T helper 3-dependent autoimmune responses in atherosclerotic mice
Zhou X, Johnston Tp, Johansson D, Parini P, Funa K, Svensson J, et al
Atherosclerosis 2009;204(2):381-7

Inflammation, Adipose Tissue, and T Cells: What Is the "Straight Skinny" on Lean Versus Fat Mice? Response
Sultan A, Hansson Gk
CIRCULATION RESEARCH 2009;105(2):E5-E5

Inflammation in atherosclerosis: from pathophysiology to practice
Libby P, Ridker Pm, Hansson Gk, Leducq Transatlantic Network On Atherothrombosis
Journal of the American College of Cardiology 2009;54(23):2129-38

Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis
Sandberg Wj, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad Fr, et al
Circulation research 2009;104(1):60-8

Inflammatory mechanisms in atherosclerosis
Hansson Gk
Journal of thrombosis and haemostasis : JTH 2009;7 Suppl 1():328-31

Kruppel-like factor KLF10 targets transforming growth factor-beta1 to regulate CD4(+)CD25(-) T cells and T regulatory cells
Cao Z, Wara Ak, Icli B, Sun X, Packard Rr, Esen F, et al
The Journal of biological chemistry 2009;284(37):24914-24

Osteoprotegerin promotes fibrous cap formation in atherosclerotic lesions of ApoE-deficient mice--brief report
Ovchinnikova O, Gylfe A, Bailey L, Nordstrom A, Rudling M, Jung C, et al
Arteriosclerosis, thrombosis, and vascular biology 2009;29(10):1478-80

T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice
Ovchinnikova O, Robertson Ak, Wagsater D, Folco Ej, Hyry M, Myllyharju J, et al
The American journal of pathology 2009;174(2):693-700

T cell-mediated inflammation in adipose tissue does not cause insulin resistance in hyperlipidemic mice
Sultan A, Strodthoff D, Robertson Ak, Paulsson-berne G, Fauconnier J, Parini P, et al
Circulation research 2009;104(8):961-8

The discovery of cellular immunity in the atherosclerotic plaque
Hansson Gk, Jonasson L
Arteriosclerosis, thrombosis, and vascular biology 2009;29(11):1714-7

The tumour necrosis factor superfamily ligand APRIL (TNFSF13) is released upon platelet activation and expressed in atherosclerosis
Sandberg Wj, Otterdal K, Gullestad L, Halvorsen B, Ragnarsson A, Froland Ss, et al
Thrombosis and haemostasis 2009;102(4):704-10

Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies
Klingenberg R, Hansson Gk
European heart journal 2009;30(23):2838-44

Use of Gene Expression Profiling to Study the Healing Process in Carotid Plaques
Razuvaev A, Ekstrand J, Agardh H, Paulsson-berne G, Hansson G, Swedenborg J, et al
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 2009;29(7):E73-E73

Vaccination against atherosclerosis? Induction of atheroprotective immunity
Hansson Gk, Nilsson J
Seminars in immunopathology 2009;31(1):95-101

Abrogation of mitochondrial transcription in smooth muscle cells impairs smooth muscle contractility and vascular tone
Jawien J, Bian Z, Sheikine Y, Olofsson Ps, Pang Y, Edholm T, et al
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2008;59(2):239-52

An uneven expression of T cell receptor V genes in the arterial wall and peripheral blood in giant cell arteritis
Schaufelberger C, Andersson R, Nordborg E, Hansson Gk, Nordborg C, Wahlstrom J
Inflammation 2008;31(6):372-83

A potential role of the CXC chemokine GROalpha in atherosclerosis and plaque destabilization: downregulatory effects of statins
Breland Um, Halvorsen B, Hol J, Oie E, Paulsson-berne G, Yndestad A, et al
Arteriosclerosis, thrombosis, and vascular biology 2008;28(5):1005-11

Autoimmunity in atherosclerosis: a protective response losing control?
Nilsson J, Hansson Gk
Journal of internal medicine 2008;263(5):464-78

CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice
Olofsson Ps, Soderstrom La, Wagsater D, Sheikine Y, Ocaya P, Lang F, et al
Circulation 2008;117(10):1292-301

CD3(+)CD4(-)CD8(-)T cells in adipose tissue-implications for type 2 diabetes and atherosclerosis?
Strodthoff D, Gerdes N, Sultan A, Robertson Ak, Berne Gp, Arner P, et al
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2008;68(2):188-189

Dendritic cells pulsed with oxidised low density lipoprotein aggravate atherosclerosis
Johansson D, Hjerpe C, Hansson G, Zhou Xh
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2008;68(2):198-199

ENHANCED EXPRESSION OF THE CHEMOKINE CXCL1 IN ATHEROSCLEROTIC DISORDERS, DOWN-REGULATORY EFFECTS OF STATIN
Breland Um, Halvorsen B, Hol J, Oie E, Yndestad A, Smith C, et al
ATHEROSCLEROSIS SUPPLEMENTS 2008;9(1):198-198

Evaluation of the T cell response to apolipoprotein B100 (ApoB100): A new opportunity for immunotherapy against atherosclerosis
Ketelhuth Dfj, Hermansson A, Wurm M, Tornberg I, Strodthoff D, Fredrikson Gn, et al
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2008;68(2):244-245

Evidence that autoimmune responses in human apolipoprotein B-100 Transgenic mice are driven by V beta 14+CD4+ T cells which can recognize native low density lipoprotein in an I-Ab restricted manner
Hermansson A, Ketelhuth Dfj, Wurm M, Tornberg I, Hansson E, Nicoletti A, et al
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2008;68(2):196-197

Introduction: atherosclerosis as inflammation: a controversial concept becomes accepted
Hansson Gk, Nilsson J
Journal of internal medicine 2008;263(5):462-3

Osteoprotegerin promotes fibrous cap formation in atherosclerotic lesions of apoe deficient mice
Ovchinnikova O, Gylfe A, Bailey L, Bergstrom S, Rudling M, Waldenstrom A, et al
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2008;68(2):199-200

Specific ablation of Foxp3(+) regulatory T cells accelerates experimental atherosclerosis in mice
Gerdes N, Klingenberg R, Strodthoff D, Lahl K, Sparwasser T, Hansson G
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2008;68(2):190-191

UNCOVERING NF-kappa B ACTIVATION AND FUNCTION IN INTIMAL DEVELOPMENT
Bu D, Xu D, Hansson G, Yan Z
ATHEROSCLEROSIS SUPPLEMENTS 2008;9(1):44-44

5-Lipoxygenase-activating protein: a potential link between innate and adaptive immunity in atherosclerosis and adipose tissue inflammation
Back M, Sultan A, Ovchinnikova O, Hansson Gk
Circulation research 2007;100(7):946-9

Letter to the Editor: Autoreactive CD4+CD28- T Cells and Acute Coronary Syndromes
Robertson Ak, Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 2007;27(3):E19-

Enhanced expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental atherosclerosis: possible pathogenic role in plaque destabilization
Damas Jk, Smith C, Oie E, Fevang B, Halvorsen B, Waehre T, et al
Arteriosclerosis, thrombosis, and vascular biology 2007;27(3):614-20

Gene expression signals involved in ischemic injury, extracellular matrix composition and fibrosis defined by global mRNA profiling of the human left ventricular myocardium
Gabrielsen A, Lawler Pr, Yongzhong W, Steinbruchel D, Blagoja D, Paulsson-berne G, et al
Journal of molecular and cellular cardiology 2007;42(4):870-83

Innate immunity, macrophage activation, and atherosclerosis
Yan Zq, Hansson Gk
Immunological reviews 2007;219():187-203

Medicine. LIGHT hits the liver
Hansson Gk
Science (New York, N.Y.) 2007;316(5822):206-7

Reduced perlecan expression and accumulation in human carotid atherosclerotic lesions
Tran Pk, Agardh He, Tran-lundmark K, Ekstrand J, Roy J, Henderson B, et al
Atherosclerosis 2007;190(2):264-70

Sphingosine-1-phosphate analogue FTY720 causes lymphocyte redistribution and hypercholesterolemia in ApoE-deficient mice
Klingenberg R, Nofer Jr, Rudling M, Bea F, Blessing E, Preusch M, et al
Arteriosclerosis, thrombosis, and vascular biology 2007;27(11):2392-9

Two views on plaque rupture
Hansson Gk, Heistad Dd
Arteriosclerosis, thrombosis, and vascular biology 2007;27(4):697-

Adoptive transfer of CD4+ T cells reactive to modified low-density lipoprotein aggravates atherosclerosis
Zhou X, Robertson Ak, Hjerpe C, Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 2006;26(4):864-70

Antimicrobial peptide LL-37 in human atherosclerosis
Edfeldt K, Agerberth B, Rottenberg Me, Gudmundsson Gh, Mandal K, Xu Qb, et al
ATHEROSCLEROSIS SUPPLEMENTS 2006;7(3):407-407

Chemokines as potential therapeutic targets in atherosclerosis
Sheikine Ya, Hansson Gk
Current drug targets 2006;7(1):13-27

Dendritic cells pulsed with oxidised low density lipoprotein aggravate atherosclerosis
Hjerpe C, Johansson D, Zhou X, Hansson Gk
ATHEROSCLEROSIS SUPPLEMENTS 2006;7(3):460-460

Dendritic cells pulsed with oxidised low density lipoprotein aggravate atherosclerosis
Hjerpe C, Johansson D, Hansson G, Zhou X
EUROPEAN HEART JOURNAL 2006;:968-969

Effect of inflammation on the glucidic metabolism: studies in the transgenic mice
Sultan A, Arner P, Hansson G
DIABETES & METABOLISM 2006;:S24-S24

Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilization
Sandberg Wj, Yndestad A, Oie E, Smith C, Ueland T, Ovchinnikova O, et al
Arteriosclerosis, thrombosis, and vascular biology 2006;26(4):857-63

Epidemiology complements immunology in the heart
Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2178-80

Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability
Qiu H, Gabrielsen A, Agardh He, Wan M, Wetterholm A, Wong Ch, et al
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8161-6

Expression of neutrophil gelatinase-associated lipocalin in atherosclerosis and myocardial infarction
Hemdahl Al, Gabrielsen A, Zhu C, Eriksson P, Hedin U, Kastrup J, et al
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):136-42

Gene deletion of NF-kappaB p105 enhances neointima formation in a mouse model of carotid artery injury
Ruusalepp A, Yan Zq, Carlsen H, Czibik G, Hansson Gk, Moskaug Jo, et al
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2006;20(2):103-11

Immune regulation in atherosclerosis
Hansson Gk, Berne G, Zhou X, Yan Zq
ATHEROSCLEROSIS SUPPLEMENTS 2006;7(3):167-168

Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation
Smith C, Damas Jk, Otterdal K, Oie E, Sandberg Wj, Yndestad A, et al
Journal of the American College of Cardiology 2006;48(8):1591-9

Inflammation and atherosclerosis
Hansson Gk, Robertson Ak, Soderberg-naucler C
Annual review of pathology 2006;1():297-329

Inflammatory response inhuman atherosclerosis : bike - Biobank of karolinska endartherectomy
Paulsson-berne G, Gabrielsen A, Agardh He, Ekstrand J, Marcus D, Bodin I, et al
ATHEROSCLEROSIS SUPPLEMENTS 2006;7(3):248-248

Inhibited collagen maturation, but only modest proteolytic activity in hyperinflamed atherosclerotic lesions
Ovchinnikova Oa, Robertson Akl, Gavrisheva Na, Shlyakhto Ev, Chaoyong Z, Ericsson P, et al
ATHEROSCLEROSIS SUPPLEMENTS 2006;7(3):242-242

Invariant NKT cells present in human atherosclerotic lesions
Agardh He, Eriksson P, Tupin E, Kazi M, Hedin U, Olsson A, et al
ATHEROSCLEROSIS SUPPLEMENTS 2006;7(3):406-406

Leukotriene B4-induced vascular inflammation: Role of NF kappa B-dependent BLT1 receptors in ion channel activation and neointimal hyperplasia
Back M, Branstrom R, Bu Dx, Sheikine Y, Yan Zq, Hansson Gk
PROSTAGLANDINS & OTHER LIPID MEDIATORS 2006;79(1-2):154-154

Leukotriene receptors in atherosclerosis
Back M, Hansson Gk
Annals of medicine 2006;38(7):493-502

Myocardial gene expression of angiogenic factors in human chronic ischemic myocardium: influence of acute ischemia/cardioplegia and reperfusion
Wang Y, Gabrielsen A, Lawler Pr, Paulsson-berne G, Steinbruchel Da, Hansson Gk, et al
Microcirculation (New York, N.Y. : 1994) 2006;13(3):187-97

Natural regulatory T cells control the development of atherosclerosis in mice
Ait-oufella H, Salomon Bl, Potteaux S, Robertson Ak, Gourdy P, Zoll J, et al
Nature medicine 2006;12(2):178-80

Pro-atherogeinc effect of CD1d-restricted NKT cells in formation of early plaque
Tupin E, Agardh He, Gerdes N, Bodin I, Nicoletti A, Hansson Gk, et al
ATHEROSCLEROSIS SUPPLEMENTS 2006;7(3):327-327

T cells in atherogenesis: for better or for worse?
Robertson Ak, Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 2006;26(11):2421-32

T cells specific for an oxidation-induced epitope in human LDL
Hermansson A, Ketelhuth Dfj, Tornberg I, Hansson E, Paulsson-berne G, Nicoletti A, et al
ATHEROSCLEROSIS SUPPLEMENTS 2006;7(3):237-237

The immune response in atherosclerosis: a double-edged sword
Hansson Gk, Libby P
Nature reviews. Immunology 2006;6(7):508-19

The immunomodulator FTY720 inhibits early atherosclerosis in ApoE-/- mice
Klingenberg R, Bea F, Blessing E, Preusch M, Groene Hj, Brinkmann V, et al
ATHEROSCLEROSIS SUPPLEMENTS 2006;7(3):407-407

Viewpoint: The immune system and atherosclerosis
Hansson Gk, Taylor J
CIRCULATION 2006;114(12):F145-F146

Atherosclerotic lesions with exaggerated inflammation show impaired collagen maturation.
Ovtchinnikova O, Robertson Ak, Hansson Gk
JOURNAL OF VASCULAR RESEARCH 2005;:80-80

ATVB in focus - Immunity and atherosclerosis
Hansson Gk
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 2005;25(1):17-17

CDR3 sequence preference of TCRBV8S2+ T cells within the CNS does not reflect single amino acid dependent avidity expansion
De Graaf Kl, Berne Gp, Herrmann Mm, Hansson Gk, Olsson T, Weissert R
Journal of neuroimmunology 2005;166(1-2):47-54

Depletion of natural CD4+CD25+ regulatory T cells enhances the development of atherosclerosis
Oufella Ha, Potteaux S, Robertson Ak, Salomon B, Merval R, Esposito B, et al
CIRCULATION 2005;112(17):U73-U73

Depletion of natural CD4+CD25+ regulatory T cells enhances the development of atherosclerosis.
Oufella Ha, Potteaux S, Salomon B, Robertson Ak, Klatzmann D, Hansson G, et al
JOURNAL OF VASCULAR RESEARCH 2005;:100-100

Electrocardiographic characterization of stress-induced myocardial infarction in atherosclerotic mice
Hemdahl Al, Caligiuri G, Hansson Gk, Thoren P
Acta physiologica Scandinavica 2005;184(2):87-94

Expression of matrix metalloproteinase 9 and its regulators in the unstable coronary atherosclerotic plaque
Chen F, Eriksson P, Hansson Gk, Herzfeld I, Klein M, Hansson Lo, et al
International journal of molecular medicine 2005;15(1):57-65

IKKbeta-dependent NF-kappaB pathway controls vascular inflammation and intimal hyperplasia
Bu Dx, Erl W, De Martin R, Hansson Gk, Yan Zq
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1293-5

Immunoglobulin treatment reduces atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice via the complement system
Persson L, Boren J, Nicoletti A, Hansson Gk, Pekna M
Clinical and experimental immunology 2005;142(3):441-5

Immunology of ischemic vascular disease: plaque to attack
Hallenbeck Jm, Hansson Gk, Becker Kj
Trends in immunology 2005;26(10):550-6

Immunomodulation of atherosclerosis: implications for vaccine development
Nilsson J, Hansson Gk, Shah Pk
Arteriosclerosis, thrombosis, and vascular biology 2005;25(1):18-28

Inflammation, atherosclerosis, and coronary artery disease - Reply
Hansson Gk
NEW ENGLAND JOURNAL OF MEDICINE 2005;353(4):429-430

Lesion development and response to immunization reveal a complex role for CD4 in atherosclerosis
Zhou X, Robertson Ak, Rudling M, Parini P, Hansson Gk
Circulation research 2005;96(4):427-34

Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia
Back M, Bu Dx, Branstrom R, Sheikine Y, Yan Zq, Hansson Gk
Proceedings of the National Academy of Sciences of the United States of America 2005;102(48):17501-6

Leukotriene-induced migration and proliferation of vascular smooth muscle cells: Implications for atherosclerosis and restenosis.
Back M, Sheikine Y, Hansson Gk
JOURNAL OF VASCULAR RESEARCH 2005;:26-26

Inflammation, atherosclerosis, and coronary artery disease
Hansson Gk
The New England journal of medicine 2005;352(16):1685-95

Reduced collagen maturation in atherosclerotic lesions with excessive T cell-mediated inflammation
Ovtchinnikova Oa, Robertson Akl, Hansson Gk
ATHEROSCLEROSIS SUPPLEMENTS 2005;6(1):17-17

Severity of coronary artery stenosis is associated with a polymorphism in the CXCL16/SR-PSOX gene
Lundberg Ga, Kellin A, Samnegard A, Lundman P, Tornvall P, Dimmeler S, et al
Journal of internal medicine 2005;257(5):415-22

The antiviral cytomegalovirus inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents
Olofsson Ps, Jatta K, Wagsater D, Gredmark S, Hedin U, Paulsson-berne G, et al
Arteriosclerosis, thrombosis, and vascular biology 2005;25(7):e113-6

The antiviral cytomegalovirus inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents
Olofsson Ps, Jatta K, Wagsater D, Gredmark S, Hedin U, Paulsson-berne G, et al
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 2005;25(7):E113-E116

The atheroprotective effect of 17beta-estradiol depends on complex interactions in adaptive immunity
Elhage R, Gourdy P, Jawien J, Brouchet L, Castano C, Fievet C, et al
The American journal of pathology 2005;167(1):267-74

Toll to be paid at the gateway to the vessel wall
Hansson Gk, Edfeldt K
Arteriosclerosis, thrombosis, and vascular biology 2005;25(6):1085-7

Up-regulated leukotriene formation in atherosclerosis
Back M, Sheikine Y, Leclercq A, Meilhac O, Haeggstrom Jz, Dahlen Se, et al
EUROPEAN HEART JOURNAL 2005;:335-335

Angiogenic profiling of the ischemic human heart in vivo
Wang Yz, Gabrielsen A, Lawler P, Paulsson Gb, Steinbruchel D, Hansson G, et al
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 2004;43(5):489A-489A

Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction
Edfeldt K, Bennet Am, Eriksson P, Frostegard J, Wiman B, Hamsten A, et al
European heart journal 2004;25(16):1447-53

Atherosclerosis and the immune system
Hansson Gk, Berne Gp
Acta paediatrica (Oslo, Norway : 1992). Supplement 2004;93(446):63-9

CD1d-dependent activation of NKT cells aggravates atherosclerosis
Tupin E, Nicoletti A, Elhage R, Rudling M, Ljunggren H, Hansson G, et al
ATHEROSCLEROSIS SUPPLEMENTS 2004;5(1):42-42

CD1d-dependent activation of NKT cells aggravates atherosclerosis
Tupin E, Nicoletti A, Elhage R, Rudling M, Ljunggren Hg, Hansson Gk, et al
The Journal of experimental medicine 2004;199(3):417-22

CD4+T cells from mice immunized with MDA-LDL are proatherogenic
Robertson Akl, Zhou X, Tenger C, Hansson Gk
ATHEROSCLEROSIS SUPPLEMENTS 2004;5(1):158-158

Chemokines and atherosclerosis
Sheikine Y, Hansson Gk
Annals of medicine 2004;36(2):98-118

CXCL16/SR-PSOX is an interferon-gamma-regulated chemokine and scavenger receptor expressed in atherosclerotic lesions
Wuttge Dm, Zhou X, Sheikine Y, Wagsater D, Stemme V, Hedin U, et al
Arteriosclerosis, thrombosis, and vascular biology 2004;24(4):750-5

Cytomegalovirus inducible gene 5 is induced in human and rodent vascular inflammation and atherosclerosis
Olofsson P, Wagsater D, Hansson G, Sirsjo A
ATHEROSCLEROSIS SUPPLEMENTS 2004;5(1):13-14

Effect of sex and age on serum biochemical reference ranges in C57BL/6J mice
Zhou X, Hansson Gk
Comparative medicine 2004;54(2):176-8

Glimpse of the secret life of the plaque
Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 2004;24(12):2203-4

Immunomodulation and vaccination for atherosclerosis
Zhou X, Hansson Gk
Expert opinion on biological therapy 2004;4(4):599-612

Interleukin 18 accelerates atherosclerosis via IFN gamma secretion independently of T cells
Tenger C, Hansson Gk, Jawien J, Sundborger A, Zhou X
ATHEROSCLEROSIS SUPPLEMENTS 2004;5(1):42-42

Lack of complement factor C3, but not factor B, increases hyperlipidemia and atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice
Persson L, Boren J, Robertson Ak, Wallenius V, Hansson Gk, Pekna M
Arteriosclerosis, thrombosis, and vascular biology 2004;24(6):1062-7

Profiling inflammation in the ischemic human heart in vivo
Gabrielsen A, Lawler P, Haeggstrom J, Paulsson Gb, Wang Yz, Steinbruchel D, et al
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 2004;43(5):283A-283A

Severe hypercholesterolaemia leads to strong Th2 responses to an exogenous antigen
Robertson Ak, Zhou X, Strandvik B, Hansson Gk
Scandinavian journal of immunology 2004;59(3):285-93

TGF-beta in atherosclerosis
Hansson Gk, Robertson Ak
Arteriosclerosis, thrombosis, and vascular biology 2004;24(6):E137-author

Thrombin inhibitor reduces myocardial infarction in apoE-/- x LDLR-/- mice
Hemdahl Al, Falk E, Thoren P, Hansson Gk
American journal of physiology. Heart and circulatory physiology 2004;287(2):H872-7

Vaccination and atherosclerosis
Zhou X, Hansson Gk
Current atherosclerosis reports 2004;6(2):158-64

ATVB in focus: Smooth muscle cells
Gabbiani G, Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 2003;23(3):379-

Cytomegalovirus inducible gene 5 is induced in human and rodent vascular inflammation and atherosclerosis
Olofsson P, Hansson Gk, Sirsjo A
CIRCULATION 2003;108(17):195-195

Deficiency of nitric oxide synthase 2 results in increased neointima formation in a mouse model of vascular injury
Sirsjo A, Lofving A, Hansson Gk, Wagsater D, Tokuno S, Valen G
Journal of cardiovascular pharmacology 2003;41(6):897-902

Disruption of TGF-beta signaling in T cells accelerates atherosclerosis
Robertson Ak, Rudling M, Zhou X, Gorelik L, Flavell Ra, Hansson Gk
The Journal of clinical investigation 2003;112(9):1342-50

Disruption of transforming growth factor-beta signalling in T cells accelerates atherosclerosis by increasing T cell activation
Robertson Ak, Rudling M, Zhou Xh, Gorelik L, Flavell Ra, Hughes H, et al
CIRCULATION 2003;108(17):163-163

Expression of Toll-like receptors in human atherosclerotic lesions and the relevance to myocardial infarction
Edfeldt K, Bennet Am, Eriksson P, Hamsten A, Hansson Gk, Defaire U, et al
EUROPEAN HEART JOURNAL 2003;:156-156

From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I
Naghavi M, Libby P, Falk E, Casscells Sw, Litovsky S, Rumberger J, et al
Circulation 2003;108(14):1664-72

From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II
Naghavi M, Libby P, Falk E, Casscells Sw, Litovsky S, Rumberger J, et al
Circulation 2003;108(15):1772-8

HMG-CoA reductase inhibitors induce apoptosis in neointima-derived vascular smooth muscle cells
Erl W, Hristov M, Neureuter M, Yan Zq, Hansson Gk, Weber Pc
Atherosclerosis 2003;169(2):251-8

Inhibition of nuclear factor-kappa B activation attenuates inflammation, and enhances neointima formation in rat and mouse models of carotid artery injury
Arno R, Bu D, Guro V, Haral C, Hansson Gk, Moskaug O, et al
EUROPEAN HEART JOURNAL 2003;:338-338

Interleukin-10 deficiency increases atherosclerosis, thrombosis, and low-density lipoproteins in apolipoprotein E knockout mice
Caligiuri G, Rudling M, Ollivier V, Jacob Mp, Michel Jb, Hansson Gk, et al
Molecular medicine (Cambridge, Mass.) 2003;9(1-2):10-7

Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice
Elhage R, Jawien J, Rudling M, Ljunggren Hg, Takeda K, Akira S, et al
Cardiovascular research 2003;59(1):234-40

Regulation of proatherosclerotic immunity
Hansson Gk
ATHEROSCLEROSIS SUPPLEMENTS 2003;4(2):4-4

Accumulation of foam cells in liver X receptor-deficient mice
Schuster Gu, Parini P, Wang L, Alberti S, Steffensen Kr, Hansson Gk, et al
Circulation 2002;106(9):1147-53

Chlamydia pneumoniae infection and atherosclerosis: Methodological considerations - Response
Caligiuri G, Rottenberg M, Wigzell T, Hansson Gk, Nicoletti A
CIRCULATION 2002;105(4):E34-E34

Cytomegalo virus inducible gene 5 (CIG5)and CIG49 are induced in human vascular inflammation
Olofsson P, Olsson A, Hansson Gk, Sirsjo A
FASEB JOURNAL 2002;16(4):A210-A210

Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation
Edfeldt K, Swedenborg J, Hansson Gk, Yan Zq
Circulation 2002;105(10):1158-61

Hyaluronic acid and chondroitin sulphate A rapidly promote differentiation of immature DC with upregulation of costimulatory and antigen-presenting molecules, and enhancement of NF-kappaB and protein kinase activity
Yang R, Yan Z, Chen F, Hansson Gk, Kiessling R
Scandinavian journal of immunology 2002;55(1):2-13

Innate and adaptive immunity in the pathogenesis of atherosclerosis
Hansson Gk, Libby P, Schonbeck U, Yan Zq
Circulation research 2002;91(4):281-91

Production of the long pentraxin PTX3 in advanced atherosclerotic plaques
Rolph Ms, Zimmer S, Bottazzi B, Garlanda C, Mantovani A, Hansson Gk
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 2002;22(5):E10-E18

Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice
Caligiuri G, Nicoletti A, Poirier B, Hansson Gk
The Journal of clinical investigation 2002;109(6):745-53

The B cell: a good guy in vascular disease?
Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 2002;22(4):523-4

The cellular immune response to oxidized LDL aggravates atherosclerosis. Evidence from adoptive transfer studies in immunodeficient mice
Zhou X, Tenger C, Robertsson Ak, Hansson G
EUROPEAN HEART JOURNAL 2002;:255-255

Vaccination against atherosclerosis: science or fiction?
Hansson Gk
Circulation 2002;106(13):1599-601

Activation of inducible nitric oxide synthase/nitric oxide by curli fibers leads to a fall in blood pressure during systemic Escherichia coli infection in mice
Bian Z, Yan Zq, Hansson Gk, Thoren P, Normark S
The Journal of infectious diseases 2001;183(4):612-9

Chlamydia pneumoniae infection does not induce or modify atherosclerosis in mice
Caligiuri G, Rottenberg M, Nicoletti A, Wigzell H, Hansson Gk
Circulation 2001;103(23):2834-8

Conserved amino acid residues in T cell receptros of atherosclerotic lesions in apoE KO mice
Paulsson G, Tornquist E, Hansson Gk
EUROPEAN HEART JOURNAL 2001;:249-249

Expression of interleukin-15 in mouse and human atherosclerotic lesions
Wuttge Dm, Eriksson P, Sirsjo A, Hansson Gk, Stemme S
The American journal of pathology 2001;159(2):417-23

Immune mechanisms in atherosclerosis
Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 2001;21(12):1876-90

Increased expression of matrix metalloproteinase 9 in atherosclerotic plaques from patients with acute coronary syndromes
Valen G, Eriksson P, Hansson Gk, Herzfeld I, Chen F
EUROPEAN HEART JOURNAL 2001;:70-70

Induction of CD36 by all-trans retinoic acid: retinoic acid receptor signaling in the pathogenesis of atherosclerosis
Wuttge Dm, Romert A, Eriksson U, Torma H, Hansson Gk, Sirsjo A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(7):1221-3

In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice
Laurat E, Poirier B, Tupin E, Caligiuri G, Hansson Gk, Bariety J, et al
Circulation 2001;104(2):197-202

LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis
Zhou X, Caligiuri G, Hamsten A, Lefvert Ak, Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 2001;21(1):108-14

Nuclear factor kappa-B and the heart
Valen G, Yan Zq, Hansson Gk
Journal of the American College of Cardiology 2001;38(2):307-14

Platelet aggregation and myocardial infarction in atherosclerotic mice
Hemdahl Al, Hansson Gk, Thoren P, Falk E
EUROPEAN HEART JOURNAL 2001;:670-670

Platelet aggregation and myocardial infarction in atherosclerotic mice
Hemdahl Al, Falk E, Thoren P, Hansson Gk
CIRCULATION 2001;104(17):118-118

Regulation of immune mechanisms in atherosclerosis
Hansson Gk
Annals of the New York Academy of Sciences 2001;947():157-65

Retinoids modulate expression of nitric oxide synthase-2 in vascular smooth muscle cells.
Olofsson P, Olsson A, Gidlof Ac, Yan Zq, Hansson Gk, Sirsjo A
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 2001;21(4):697-697

The stabilized plaque: will the dream come true?
Hansson Gk
EUROPEAN HEART JOURNAL SUPPLEMENTS 2001;3(C):C69-C75

Elevated inflammatory parameters are associated with lower platelet density in acute myocardial infarctions with ST-elevation
Jaremo P, Hansson G, Nilsson O
Thrombosis research 2000;100(6):471-8

Evidence for antigen-driven T-cell response in unstable angina
Caligiuri G, Paulsson G, Nicoletti A, Maseri A, Hansson Gk
Circulation 2000;102(10):1114-9

Expression of cyclo-oxygenase-2 in human atherosclerotic carotid arteries
Stemme V, Swedenborg J, Claesson H, Hansson Gk
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2000;20(2):146-52

Gene expression of inflammatory mediators in different chambers of the human heart
Valen G, Paulsson G, Bennet Am, Hansson Gk, Vaage J
The Annals of thoracic surgery 2000;70(2):562-7

Immunological aspects of cardiovascular diseases - Introduction
Lefvert Ak, Hansson Gk
JOURNAL OF INTERNAL MEDICINE 2000;247(3):348-348

Immunomodulation of atherosclerosis: myth and reality
Nicoletti A, Caligiuri G, Hansson Gk
Journal of internal medicine 2000;247(3):397-405

Induction of macrophage nitric oxide, inducible nitric oxide synthase and nuclear factor-kappa B by Ureaplasma urealyticum and inhibition by steroids
Li Yh, Yan Zq, Hansson Gk, Jensen Js, Lagercrantz H, Brauner A, et al
PEDIATRIC RESEARCH 2000;47(4):367A-367A

Induction of neonatal tolerance to oxidized lipoprotein reduces atherosclerosis in ApoE knockout mice
Nicoletti A, Paulsson G, Caligiuri G, Zhou X, Hansson Gk
Molecular medicine (Cambridge, Mass.) 2000;6(4):283-90

Oligoclonal T cell expansions in atherosclerotic lesions of apolipoprotein E-deficient mice
Paulsson G, Zhou X, Tornquist E, Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 2000;20(1):10-7

Pyrrolidine dithiocarbamate-induced apoptosis depends on cell type, density, and the presence of Cu(2+) and Zn(2+)
Erl W, Weber C, Hansson Gk
American journal of physiology. Cell physiology 2000;278(6):C1116-25

Retinoic acid inhibits nitric oxide synthase-2 expression through the retinoic acid receptor-alpha
Sirsjo A, Gidlof Ac, Olsson A, Torma H, Ares M, Kleinert H, et al
Biochemical and biophysical research communications 2000;270(3):846-51

Role of IL-10 in atherosclerotic plaque stability
Caligiuri G, Ollivier V, Hansson Gk, Michel Jb
EUROPEAN HEART JOURNAL 2000;:162-162

The role of adaptive immunity in atherosclerosis
Hansson Gk, Zhou X, Tornquist E, Paulsson G
Annals of the New York Academy of Sciences 2000;902():53-62

Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice
Zhou X, Nicoletti A, Elhage R, Hansson Gk
Circulation 2000;102(24):2919-22

Unstable angina activates myocardial heat shock protein 72, endothelial nitric oxide synthase, and transcription factors NFkappaB and AP-1
Valen G, Hansson Gk, Dumitrescu A, Vaage J
Cardiovascular research 2000;47(1):49-56

An immunohistochemical study of inducible nitric oxide synthase in the rat middle ear, with reference to tympanosclerosis
Forseni M, Hansson Gk, Bagger-sjoback D, Hultcrantz M
Acta oto-laryngologica 1999;119(5):577-82

Atherosclerosis update
Hansson Gk
ATHEROSCLEROSIS 1999;:3-3

Augmented expression of inducible NO synthase in vascular smooth muscle cells during aging is associated with enhanced NF-kappaB activation
Yan Zq, Sirsjo A, Bochaton-piallat Ml, Gabbiani G, Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 1999;19(12):2854-62

Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines
Frostegard J, Ulfgren Ak, Nyberg P, Hedin U, Swedenborg J, Andersson U, et al
Atherosclerosis 1999;145(1):33-43

Detection of B cells and proinflammatory cytokines in atherosclerotic plaques of hypercholesterolaemic apolipoprotein E knockout mice
Zhou X, Hansson Gk
Scandinavian journal of immunology 1999;50(1):25-30

Effects of sex and age on atherosclerosis and autoimmunity in apoE-deficient mice
Caligiuri G, Nicoletti A, Zhou X, Tornberg I, Hansson Gk
Atherosclerosis 1999;145(2):301-8

Enhanced phenylephrine-induced rhythmic activity in the atherosclerotic mouse aorta via an increase in opening of KCa channels: relation to Kv channels and nitric oxide
Jiang J, Thoren P, Caligiuri G, Hansson Gk, Pernow J
British journal of pharmacology 1999;128(3):637-46

Functionality of specific immunity in atherosclerosis
Nicoletti A, Caligiuri G, Paulsson G, Hansson Gk
American heart journal 1999;138(5 Pt 2):S438-43

Hydrogen peroxide induces mRNA for tumour necrosis factor alpha in human endothelial cells
Valen G, Erl W, Eriksson P, Wuttge D, Paulsson G, Hansson Gk
Free radical research 1999;31(6):503-12

Infiltration of immunocompetent cells in the middle ear during acute otitis media: a temporal study
Forseni M, Hansson Gk, Bagger-sjoback D, Hultcrantz M
The American journal of otology 1999;20(2):152-7

Inflammation and immune response in atherosclerosis
Hansson Gk
Current atherosclerosis reports 1999;1(2):150-5

Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic mice
Caligiuri G, Levy B, Pernow J, Thoren P, Hansson Gk
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6920-4

Nitric oxide metabolites in CSF of patients with MS are related to clinical disease course
Svenningsson A, Petersson As, Andersen O, Hansson Gk
Neurology 1999;53(8):1880-2

Nuclear factor-kappa B regulates induction of apoptosis and inhibitor of apoptosis protein-1 expression in vascular smooth muscle cells
Erl W, Hansson Gk, De Martin R, Draude G, Weber Ks, Weber C
Circulation research 1999;84(6):668-77

Retinoic acid regulates arterial smooth muscle cell proliferation and phenotypic features in vivo and in vitro through an RARalpha-dependent signaling pathway
Neuville P, Yan Z, Gidlof A, Pepper Ms, Hansson Gk, Gabbiani G, et al
Arteriosclerosis, thrombosis, and vascular biology 1999;19(6):1430-6

The contribution of inducible nitric oxide and cytomegalovirus to the stability of complex carotid plaque
Hunter Gc, Henderson Am, Westerband A, Kobayashi H, Suzuki F, Yan Zq, et al
Journal of vascular surgery 1999;30(1):36-49

The macrophage scavenger receptor type A directs modified proteins to antigen presentation
Nicoletti A, Caligiuri G, Tornberg I, Kodama T, Stemme S, Hansson Gk
European journal of immunology 1999;29(2):512-21

[1998 Nobel Prize in physiology or medicine. Nitric oxide as a signal molecule in the cardiovascular system]
Hansson Gk, Jornvall H, Lindahl Sg
Lakartidningen 1998;95(43):4703-8

Antibody titers against oxidized LDL are not elevated in patients with familial hypercholesterolemia
Hulthe J, Wikstrand J, Lidell A, Wendelhag I, Hansson Gk, Wiklund O
Arteriosclerosis, thrombosis, and vascular biology 1998;18(8):1203-11

Atherosclerosis: cell biology and lipoproteins
Hansson Gk
Current opinion in lipidology 1998;9(1):73-5

Hypercholesterolemia is associated with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice
Zhou X, Paulsson G, Stemme S, Hansson Gk
The Journal of clinical investigation 1998;101(8):1717-25

Immunoglobulin treatment reduces atherosclerosis in apo E knockout mice
Nicoletti A, Kaveri S, Caligiuri G, Bariety J, Hansson Gk
The Journal of clinical investigation 1998;102(5):910-8

Inflammation and immunology - critical issues - Immune mechanisms in vascular disease
Hansson Gk
JOURNAL OF VASCULAR SURGERY 1998;27(6):1152-1192

Intravenous immunoglobulin treatment reduces atherosclerosis in ApoE knockout mice: Pathogenic implications
Nicoletti A, Kayeri S, Caligiuri G, Hansson Gk
FASEB JOURNAL 1998;12(4):A310-A310

Ischaemic heart disease in primary immunodeficiency
Hammar N, Linnersjo A, Hansson Gk, Bjorkander J, Hammarstrom L
Lancet (London, England) 1998;352(9142):1786-

Overexpression of inducible nitric oxide synthase by neointimal smooth muscle cells
Yan Z, Hansson Gk
Circulation research 1998;82(1):21-9

Scavenger receptors mediate adhesion of activated B lymphocytes
Yokota T, Ehlin-henriksson B, Hansson Gk
Experimental cell research 1998;239(1):16-22

Autoimmunity in atherosclerosis
Hansson Gk, Stemme S, Paulsson G, Zhou Xh, Bruzelius M, Caligiuri G, et al
ATHEROSCLEROSIS 1997;134(1-2):289-289

Cell-mediated immunity in atherosclerosis
Hansson Gk
Current opinion in lipidology 1997;8(5):301-11

Intravenous immunoglobulins infusion protects apoE knockout mice from atherosclerosis
Nicoletti A, Kaveri S, Hansson Gk
ATHEROSCLEROSIS 1997;134(1-2):281-281

Nitric oxide generation by nitric oxide synthase isoforms in transplanted vessels
Akyurek Ml, Hansson Gk, Larsson E, Fellstrom Bc
Transplantation proceedings 1997;29(6):2571-2

[Vascular immune reactions in arteritis and atherosclerosis. Receptors for endothelial adhesion]
Hansson G
Lakartidningen 1997;94(10):852-4

Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 beta
Geng Yj, Wu Q, Muszynski M, Hansson Gk, Libby P
Arteriosclerosis, thrombosis, and vascular biology 1996;16(1):19-27

Apoptotic death of human leukemic cells induced by vascular cells expressing nitric oxide synthase in response to gamma-interferon and tumor necrosis factor-alpha
Geng Yj, Hellstrand K, Wennmalm A, Hansson Gk
Cancer research 1996;56(4):866-74

Atherosclerosis and expression of the neuro-immune-endocrine system - Reply
Yokota T, Hansson Gk
JOURNAL OF INTERNAL MEDICINE 1996;240(1):51-51

Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apolipoprotein-E-deficient mice
Zhou X, Stemme S, Hansson Gk
The American journal of pathology 1996;149(2):359-66

Expression of inducible nitric oxide synthase inhibits platelet adhesion and restores blood flow in the injured artery
Yan Zq, Yokota T, Zhang W, Hansson Gk
Circulation research 1996;79(1):38-44

Inducible and endothelial nitric oxide synthase expression during development of transplant arteriosclerosis in rat aortic grafts
Akyurek Lm, Fellstrom Bc, Yan Zq, Hansson Gk, Funa K, Larsson E
The American journal of pathology 1996;149(6):1981-90

Differential regulation of macrophage scavenger receptor isoforms: mRNA quantification using the polymerase chain reaction
Dufva M, Svenningsson A, Hansson Gk
Journal of lipid research 1995;36(11):2282-90

EXPANSIONS OF T-CELLS EXPRESSING SELECTED TCR-V GENE SEGMENTS IN GIANT-CELL ARTERITIS
Schaufelberger C, Nordborg C, Andersson R, Nordberg E, Hansson Gk, Wahlstom J, et al
ARTHRITIS AND RHEUMATISM 1995;38(9):1501-1501

Expression of the macrophage scavenger receptor in atheroma. Relationship to immune activation and the T-cell cytokine interferon-gamma
Geng Yj, Holm J, Nygren S, Bruzelius M, Stemme S, Hansson Gk
Arteriosclerosis, thrombosis, and vascular biology 1995;15(11):1995-2002

High endothelial cells of postcapillary venules express the scavenger receptor in human peripheral lymph nodes
Geng Yj, Hansson Gk
Scandinavian journal of immunology 1995;42(3):289-96

Immunological mechanisms in atherosclerosis
Yokota T, Hansson Gk
Journal of internal medicine 1995;238(6):479-89

Induction of nitric oxide synthase in a model of allergic occupational asthma
Yan Zq, Hansson Gk, Skoogh Be, Lotvall Jo
Allergy 1995;50(9):760-4

Reduced frequency of memory CD8+ T lymphocytes in cerebrospinal fluid and blood of patients with multiple sclerosis
Svenningsson A, Andersen O, Hansson Gk, Stemme S
Autoimmunity 1995;21(4):231-9

T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein
Stemme S, Faber B, Holm J, Wiklund O, Witztum Jl, Hansson Gk
Proceedings of the National Academy of Sciences of the United States of America 1995;92(9):3893-7

Visa alla publikationer