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Eva Kosek

Professor/överläkare

Besöksadress : Nobels Väg 9 171 77 Stockholm
Postadress : Institutionen för klinisk neurovetenskap (CNS), K8, Neuro Kosek, Nobels väg 9, 171 77 Stockholm

Publikationer

Are there different predictors of analgesic response between antidepressants and anticonvulsants in painful diabetic neuropathy?
Marchettini P, Wilhelm S, Petto H, Tesfaye S, Tölle T, Bouhassira D, et al
European journal of pain (London, England) 2016;20(3):472-82

Decrease of fear avoidance beliefs following person-centered progressive resistance exercise contributes to reduced pain disability in women with fibromyalgia: secondary exploratory analyses from a randomized controlled trial
Palstam A, Larsson A, Löfgren M, Ernberg M, Bjersing J, Bileviciute-ljungar I, et al
Arthritis research & therapy 2016;18(1):116-

Do we need a third mechanistic descriptor for chronic pain states?
Kosek E, Cohen M, Baron R, Gebhart Gf, Mico Ja, Rice As, et al
Pain 2016;157(7):1382-6

Effects of 15 weeks of resistance exercise on pro-inflammatory cytokine levels in the vastus lateralis muscle of patients with fibromyalgia
Ernberg M, Christidis N, Ghafouri B, Bileviciute-ljungar I, Löfgren M, Larsson A, et al
Arthritis research & therapy 2016;18(1):137-

Intrinsic Brain Connectivity in Chronic Pain: A Resting-State fMRI Study in Patients with Rheumatoid Arthritis
Flodin P, Martinsen S, Altawil R, Waldheim E, Lampa J, Kosek E, et al
Frontiers in human neuroscience 2016;10():107-

In vivo evidence of a functional association between immune cells in blood and brain in healthy human subjects
Kanegawa N, Collste K, Forsberg A, Schain M, Arakawa R, Jucaite A, et al
Brain, behavior, and immunity 2016;54():149-57

Resistance exercise improves physical fatigue in women with fibromyalgia: a randomized controlled trial
Ericsson A, Palstam A, Larsson A, Löfgren M, Bileviciute-ljungar I, Bjersing J, et al
Arthritis research & therapy 2016;18():176-

Why sickness hurts: A central mechanism for pain induced by peripheral inflammation
Karshikoff B, Jensen Kb, Kosek E, Kalpouzos G, Soop A, Ingvar M, et al
Brain, behavior, and immunity 2016;57():38-46

A classification of chronic pain for ICD-11
Treede Rd, Rief W, Barke A, Aziz Q, Bennett Mi, Benoliel R, et al
Pain 2015;156(6):1003-7

Comparison of the Levels of Pro-Inflammatory Cytokines Released in the Vastus Lateralis Muscle of Patients with Fibromyalgia and Healthy Controls during Contractions of the Quadriceps Muscle--A Microdialysis Study
Christidis N, Ghafouri B, Larsson A, Palstam A, Mannerkorpi K, Bileviciute-ljungar I, et al
PloS one 2015;10(12):e0143856-

Evidence of different mediators of central inflammation in dysfunctional and inflammatory pain--interleukin-8 in fibromyalgia and interleukin-1 β in rheumatoid arthritis
Kosek E, Altawil R, Kadetoff D, Finn A, Westman M, Le Maître E, et al
Journal of neuroimmunology 2015;280():49-55

Modality and sex differences in pain sensitivity during human endotoxemia
Karshikoff B, Lekander M, Soop A, Lindstedt F, Ingvar M, Kosek E, et al
Brain, behavior, and immunity 2015;46():35-43

Normalization of aberrant resting state functional connectivity in fibromyalgia patients following a three month physical exercise therapy
Flodin P, Martinsen S, Mannerkorpi K, Löfgren M, Bileviciute-ljungar I, Kosek E, et al
NeuroImage. Clinical 2015;9():134-9

Resistance exercise improves muscle strength, health status and pain intensity in fibromyalgia--a randomized controlled trial
Larsson A, Palstam A, Löfgren M, Ernberg M, Bjersing J, Bileviciute-ljungar I, et al
Arthritis research & therapy 2015;17():161-

Systemic differences in serum metabolome: a cross sectional comparison of women with localised and widespread pain and controls
Hadrévi J, Björklund M, Kosek E, Hällgren S, Antti H, Fahlström M, et al
Scientific reports 2015;5():15925-

Fibromyalgia is associated with decreased connectivity between pain- and sensorimotor brain areas
Flodin P, Martinsen S, Löfgren M, Bileviciute-ljungar I, Kosek E, Fransson P
Brain connectivity 2014;4(8):587-94

Fibromyalgia patients had normal distraction related pain inhibition but cognitive impairment reflected in caudate nucleus and hippocampus during the Stroop Color Word Test
Martinsen S, Flodin P, Berrebi J, Löfgren M, Bileviciute-ljungar I, Ingvar M, et al
PloS one 2014;9(9):e108637-

Neuropathic pain phenotyping as a predictor of treatment response in painful diabetic neuropathy: data from the randomized, double-blind, COMBO-DN study
Bouhassira D, Wilhelm S, Schacht A, Perrot S, Kosek E, Cruccu G, et al
Pain 2014;155(10):2171-9

Perceived exertion at work in women with fibromyalgia: explanatory factors and comparison with healthy women
Palstam A, Larsson A, Bjersing J, Löfgren M, Ernberg M, Bileviciute-ljungar I, et al
Journal of rehabilitation medicine 2014;46(8):773-80

Segregating the cerebral mechanisms of antidepressants and placebo in fibromyalgia
Jensen Kb, Petzke F, Carville S, Choy E, Fransson P, Gracely Rh, et al
The journal of pain : official journal of the American Pain Society 2014;15(12):1328-37

Acceptance and commitment therapy for fibromyalgia: a randomized controlled trial
Wicksell Rk, Kemani M, Jensen K, Kosek E, Kadetoff D, Sorjonen K, et al
European journal of pain (London, England) 2013;17(4):599-611

Effects of neuromuscular training (NEMEX-TJR) on patient-reported outcomes and physical function in severe primary hip or knee osteoarthritis: a controlled before-and-after study
Ageberg E, Nilsdotter A, Kosek E, Roos Em
BMC MUSCULOSKELETAL DISORDERS 2013;:232-

Higher pain sensitivity and lower muscle strength in postmenonpausal women with early rheumatoid arthritis compared with age-matched healthy women--a pilot study
Fridén C, Thoors U, Glenmark B, Kosek E, Nordmark B, Lundberg Ie, et al
Disability and rehabilitation 2013;35(16):1350-6

Increased pain sensitivity but normal function of exercise induced analgesia in hip and knee osteoarthritis--treatment effects of neuromuscular exercise and total joint replacement
Kosek E, Roos Em, Ageberg E, Nilsdotter A
Osteoarthritis and cartilage 2013;21(9):1299-307

Overlapping Structural and Functional Brain Changes in Patients With Long-Term Exposure to Fibromyalgia Pain
Jensen Kb, Srinivasan P, Spaeth R, Tan Y, Kosek E, Petzke F, et al
ARTHRITIS AND RHEUMATISM 2013;65(12):3293-303

Cognitive Behavioral Therapy increases pain-evoked activation of the prefrontal cortex in patients with fibromyalgeia
Jensen Kb, Kosek E, Wicksell R, Kemani M, Olsson G, Merle Jv, et al
PAIN 2012;153(7):1495-503

Cognitive Behavioral Therapy increases pain-evoked activation of the prefrontal cortex in patients with fibromyalgia (vol 153, pg 1495, 2012)
Jensen Kb, Kosek E, Wicksell R, Kemani M, Olsson G, Merle Jv, et al
PAIN 2012;153(9):1981-1981

Dysfunctional Endogenous Analgesia During Exercise in Patients with Chronic Pain: To Exercise or Not to Exercise?
Nijs J, Kosek E, Van Oosterwijck J, Meeus M
PAIN PHYSICIAN 2012;15(3):ES205-13

Evidence of central inflammation in fibromyalgia - Increased cerebrospinal fluid interleukin-8 levels
Kadetoff D, Lampa J, Westman M, Andersson M, Kosek E
JOURNAL OF NEUROIMMUNOLOGY 2012;242(1-2):33-8

Patients with fibromyalgia display less functional connectivity in the brain's pain inhibitory network
Jensen Kb, Loitoile R, Kosek E, Petzke F, Carville S, Fransson P, et al
MOLECULAR PAIN 2012;:32-

Peripheral inflammatory disease associated with centrally activated IL-1 system in humans and mice
Lampa J, Westman M, Kadetoff D, Agreus An, Le Maitre E, Gillis-haegerstrand C, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2012;109(31):12728-33

Serotonin-1A Receptor Polymorphism (rs6295) Associated with Thermal Pain Perception
Lindstedt F, Karshikoff B, Schalling M, Hoglund Co, Ingvar M, Lekander M, et al
PLOS ONE 2012;7(8):e43221-

Conditioned Pain Modulation Is Associated with Common Polymorphisms in the Serotonin Transporter Gene
Lindstedt F, Berrebi J, Greayer E, Lonsdorf Tb, Schalling M, Ingvar M, et al
PLOS ONE 2011;6(3):e18252-

Evidence for Thalamic Involvement in the Thermal Grill Illusion: An fMRI Study
Lindstedt F, Johansson B, Martinsen S, Kosek E, Fransson P, Ingvar M
PLOS ONE 2011;6(11):e27075-

Perception of Thermal Pain and the Thermal Grill Illusion Is Associated with Polymorphisms in the Serotonin Transporter Gene
Lindstedt F, Lonsdorf Tb, Schalling M, Kosek E, Ingvar M
PLOS ONE 2011;6(3):e17752-

Anxiety and Depressive Symptoms in Fibromyalgia Are Related to Poor Perception of Health but Not to Pain Sensitivity or Cerebral Processing of Pain
Jensen Kb, Petzke F, Carville S, Fransson P, Marcus H, Williams Scr, et al
ARTHRITIS AND RHEUMATISM 2010;62(11):3488-95

Dysfunction of endogenous pain inhibition during exercise with painful muscles in patients with shoulder myalgia and fibromyalgia
Lannersten L, Kosek E
PAIN 2010;151(1):77-86

EVIDENCE OF REDUCED SYMPATHO-ADRENAL AND HYPOTHALAMIC-PITUITARY ACTIVITY DURING STATIC MUSCULAR WORK IN PATIENTS WITH FIBROMYALGIA
Kadetoff D, Kosek E
JOURNAL OF REHABILITATION MEDICINE 2010;42(8):765-72

Evidence of dysfunctional pain inhibition in Fibromyalgia reflected in rACC during provoked pain
Jensen Kb, Kosek E, Petzke F, Carville S, Fransson P, Marcus H, et al
PAIN 2009;144(1-2):95-100

Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans
Kosek E, Jensen Kb, Lonsdorf Tb, Schalling M, Ingvar M
MOLECULAR PAIN 2009;:37-

Increased Sensitivity to Thermal Pain Following a Single Opiate Dose Is Influenced by the COMT val(158)met Polymorphism
Jensen Kb, Lonsdorf Tb, Schalling M, Kosek E, Ingvar M
PLOS ONE 2009;4(6):e6016-

THE EFFECT OF MILNACIPRAN ON EVOKED PAIN IN FIBROMYALGIA: A PSYCHOPHYSICAL AND FUNCTIONAL MRI ANALYSIS
Choy E, Carville S, Williams S, Jensen K, Kosek E, Ingvar M, et al
RHEUMATOLOGY 2009;:I13-I13

EULAR evidence-based recommendations for the management of fibromyalgia syndrome
Carville Sf, Arendt-nielsen S, Bliddal H, Blotman F, Branco Jc, Buskila D, et al
ANNALS OF THE RHEUMATIC DISEASES 2008;67(4):536-41

[Fibromyalgia internationally accepted concept. Pharmacological treatment now possible]
Nisell R, Kosek E
Lakartidningen 2008;105(35):2328-32

FMRI evidence for modulation of pain by milnacipran in fibromyalgja
Petzke F, Marcus H, Jensen K, Kosek E, Ingvar M, Choy E, et al
ARTHRITIS AND RHEUMATISM 2008;58(9):S434-S434

Mechanisms of pain referral in patients with whiplash associated disorder
Kosek E, Januszewska A
EUROPEAN JOURNAL OF PAIN 2008;12(5):650-60

The effect of milnacipran on tenderness in fibromyalgia: a psychophysical and fMRI analysis
Gracely Rh, Jensen K, Kosek E, Ingvar M, Fransson P, Marcus H, et al
EUROPEAN NEUROPSYCHOPHARMACOLOGY 2008;:S580-S580

Comparison of vibration perception thresholds in individuals with diffuse upper limb pain and carpal tunnel syndrome
Tucker At, White Pd, Kosek E, Pearson Rm, Henderson M, Coldrick Ar, et al
PAIN 2007;127(3):263-9

The effects of static muscular contraction on blood pressure, heart rate, pain ratings and pressure pain thresholds in healthy individuals and patients with fibromyalgia
Kadetoff D, Kosek E
EUROPEAN JOURNAL OF PAIN 2007;11(1):39-47

Decreased muscle blood flow in fibromyalgia patients during standardised muscle exercise: A contrast media enhanced colour doppler study
Elvin A, Sioteen Ak, Nilsson A, Kosek E
EUROPEAN JOURNAL OF PAIN 2006;10(2):137-44

Eular evidence based recommendations for the management of fibromyalgia
Carville Sf, Arendt-neilson L, Bliddal H, Blotman F, Branco Jc, Buskila D, et al
ANNALS OF THE RHEUMATIC DISEASES 2006;:3-3

Perceptual integration of intramuscular electrical stimulation in the focal and the referred pain area in healthy humans
Kosek E, Hansson P
PAIN 2003;105(1-2):125-31

Segmental and plurisegmental modulation of pressure pain thresholds during static muscle contractions in healthy individuals
Kosek E, Lundberg L
EUROPEAN JOURNAL OF PAIN 2003;7(3):251-8

Somatosensory perception in patients suffering from long-term trapezius myalgia at the site overlying the most painful part of the muscle and in an area of pain referral
Leffler As, Hansson P, Kosek E
EUROPEAN JOURNAL OF PAIN 2003;7(3):267-76

[When pain goes its own ways. Mechanism-based diagnostics would make the correct choice of treatment for patients with chronic pain easier]
Kosek E
Lakartidningen 2003;100(18):1600-2

Quantitative and qualitative perceptual analysis of cold dysesthesia and hyperalgesia in fibromyalgia
Berglund B, Harju El, Kosek E, Lindblom U
PAIN 2002;96(1-2):177-87

Somatosensory perception and function of diffuse noxious inhibitory controls (DNIC) in patients suffering from rheumatoid arthritis
Leffler As, Kosek E, Lerndal T, Nordmark B, Hansson P
EUROPEAN JOURNAL OF PAIN 2002;6(2):161-76

Somatosensory perception in a remote pain-free area and function of diffuse noxious inhibitory controls (DNIC) in patients suffering from long-term trapezius myalgia
Leffler As, Hansson P, Kosek E
EUROPEAN JOURNAL OF PAIN 2002;6(2):149-59

The influence of experimental pain intensity in the local and referred pain area on somatosensory perception in the area of referred pain
Kosek E, Hansson P
EUROPEAN JOURNAL OF PAIN 2002;6(6):413-25

Abnormalities of somatosensory perception in patients with painful osteoarthritis normalize following successful treatment
Kosek E, Ordeberg G
EUROPEAN JOURNAL OF PAIN-LONDON 2000;4(3):229-38

Injection of hypertonic saline into musculus infraspinatus resulted in referred pain and sensory disturbances in the ipsilateral upper arm
Leffler As, Kosek E, Hansson P
EUROPEAN JOURNAL OF PAIN-LONDON 2000;4(1):73-82

Lack of pressure pain modulation by heterotopic noxious conditioning stimulation in patients with painful osteoarthritis before, but not following, surgical pain relief
Kosek E, Ordeberg G
PAIN 2000;88(1):69-78

The influence of pain intensity on somatosensory perception in patients suffering from subacute/chronic lateral epicondylalgia
Leffler As, Kosek E, Hansson P
EUROPEAN JOURNAL OF PAIN-LONDON 2000;4(1):57-71

Pressure pain thresholds in different tissues in one body region - The influence of skin sensitivity in pressure algometry
Kosek E, Ekholm J, Hansson P
SCANDINAVIAN JOURNAL OF REHABILITATION MEDICINE 1999;31(2):89-93

Modulatory influence on somatosensory perception from vibration and heterotopic noxious conditioning stimulation (HNCS) in fibromyalgia patients and healthy subjects
Kosek E, Hansson P
PAIN 1997;70(1):41-51

Increased pressure pain sensibility in fibromyalgia patients is located deep to the skin but not restricted to muscle tissue (vol 63, pg 335, 1995)
Kosek E, Ekholm J, Hansson P
PAIN 1996;64(3):605-605

Modulation of pressure pain thresholds during and following isometric contraction in patients with fibromyalgia and in healthy controls
Kosek E, Ekholm J, Hansson P
PAIN 1996;64(3):415-23

Modulation of pressure pain thresholds during and following isometric contraction (vol 61, pg 481, 1995)
Kosek E, Ekholm J
PAIN 1996;64(3):603-603

Sensory dysfunction in fibromyalgia patients with implications for pathogenic mechanisms
Kosek E, Ekholm J, Hansson P
PAIN 1996;68(2-3):375-83

Increased pressure pain sensibility in fibromyalgia patients is located deep to the skin but not restricted to muscle tissue
Kosek E, Ekholm J, Hansson P
PAIN 1995;63(3):335-9

MODULATION OF PRESSURE PAIN THRESHOLDS DURING AND FOLLOWING ISOMETRIC CONTRACTION
Kosek E, Ekholm J
PAIN 1995;61(3):481-6

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