Andre Ortlieb Guerreiro-Cacais

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: EMBO REPORTS. 2022;23(7):e54499

Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.

Zhu K; Wang Y; Sarlus H; Geng K; Nutma E; Sun J; Kung S-Y; Bay C; Han J; Min J-H; Benito-Cuesta I; Lund H; Amor S; Wang J; Zhang X-M; Kutter C; Guerreiro-Cacais AO; Högberg B; Harris RA
Article: SCIENCE ADVANCES. 2022;8(17):eabn1823

Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis.

Bronge M; Högelin KA; Thomas OG; Ruhrmann S; Carvalho-Queiroz C; Nilsson OB; Kaiser A; Zeitelhofer M; Holmgren E; Linnerbauer M; Adzemovic MZ; Hellström C; Jelcic I; Liu H; Nilsson P; Hillert J; Brundin L; Fink K; Kockum I; Tengvall K; Martin R; Tegel H; Gräslund T; Al Nimer F; Guerreiro-Cacais AO; Khademi M; Gafvelin G; Olsson T; Grönlund H
Article: SCIENCE IMMUNOLOGY. 2020;5(52):eabb5077

Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation.

Berglund R; Guerreiro-Cacais AO; Adzemovic MZ; Zeitelhofer M; Lund H; Ewing E; Ruhrmann S; Nutma E; Parsa R; Thessen-Hedreul M; Amor S; Harris RA; Olsson T; Jagodic M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(6):3103-3113

IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints.

Panda SK; Wigerblad G; Jiang L; Jiménez-Andrade Y; Iyer VS; Shen Y; Boddul SV; Guerreiro-Cacais AO; Raposo B; Kasza Z; Wermeling F
Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(2):838-852

C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation.

N'diaye M; Brauner S; Flytzani S; Kular L; Warnecke A; Adzemovic MZ; Piket E; Min J-H; Edwards W; Mela F; Choi HY; Magg V; James T; Linden M; Reichardt HM; Daws MR; van Horssen J; Kockum I; Harris RA; Olsson T; Guerreiro-Cacais AO; Jagodic M
Article: JOURNAL OF IMMUNOLOGY. 2019;203(4):888-898

IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis.

Lindahl H; Guerreiro-Cacais AO; Bedri SK; Linnerbauer M; Lindén M; Abdelmagid N; Tandre K; Hollins C; Irving L; Glover C; Jones C; Alfredsson L; Rönnblom L; Kockum I; Khademi M; Jagodic M; Olsson T
Article: NATURE MEDICINE. 2018;24(12):1837-1844

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis.

Falcão AM; van Bruggen D; Marques S; Meijer M; Jäkel S; Agirre E; Samudyata; Floriddia EM; Vanichkina DP; Ffrench-Constant C; Williams A; Guerreiro-Cacais AO; Castelo-Branco G
Article: NATURE IMMUNOLOGY. 2018;19(5):435-7

Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling.

Lund H; Pieber M; Parsa R; Grommisch D; Ewing E; Kular L; Han J; Zhu K; Nijssen J; Hedlund E; Needhamsen M; Ruhrmann S; Guerreiro-Cacais AO; Berglund R; Forteza MJ; Ketelhuth DFJ; Butovsky O; Jagodic M; Zhang X-M; Harris RA
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(9):E1678-E1687

Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis ‬.

Zeitelhofer M; Adzemovic MZ; Gomez-Cabrero D; Bergman P; Hochmeister S; N'diaye M; Paulson A; Ruhrmann S; Almgren M; Tegnér JN; Ekström TJ; Guerreiro-Cacais AO; Jagodic M
Article: GENES AND IMMUNITY. 2017;18(1):48-56

VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis.

Guerreiro-Cacais AO; Norin U; Gyllenberg A; Berglund R; Beyeen AD; Rheumatoid Arthritis Consortium International (RAC; Petit-Teixeira E; Cornélis F; Saoudi A; Fournié GJ; Holmdahl R; Alfredsson L; Klareskog L; Jagodic M; Olsson T; Kockum I; Padyukov L
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2016;213(8):1537-1553

BAFF-secreting neutrophils drive plasma cell responses during emergency granulopoiesis.

Parsa R; Lund H; Georgoudaki A-M; Zhang X-M; Ortlieb Guerreiro-Cacais A; Grommisch D; Warnecke A; Croxford AL; Jagodic M; Becher B; Karlsson MCI; Harris RA
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2016;99(3):437-446

Rat bone marrow-derived dendritic cells generated with GM-CSF/IL-4 or FLT3L exhibit distinct phenotypical and functional characteristics.

N'diaye M; Warnecke A; Flytzani S; Abdelmagid N; Ruhrmann S; Olsson T; Jagodic M; Harris RA; Guerreiro-Cacais AO
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(8):2188-2193

Anoctamin 2 identified as an autoimmune target in multiple sclerosis.

Ayoglu B; Mitsios N; Kockum I; Khademi M; Zandian A; Sjöberg R; Forsström B; Bredenberg J; Lima Bomfim I; Holmgren E; Grönlund H; Guerreiro-Cacais AO; Abdelmagid N; Uhlén M; Waterboer T; Alfredsson L; Mulder J; Schwenk JM; Olsson T; Nilsson P
Article: JOURNAL OF NEUROINFLAMMATION. 2015;12:194

MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulated.

Flytzani S; Guerreiro-Cacais AO; N'diaye M; Lindner M; Linington C; Meinl E; Stridh P; Jagodic M; Olsson T
Article: MOLECULAR PAIN. 2014;10:78

Variability in C-type lectin receptors regulates neuropathic pain-like behavior after peripheral nerve injury.

Dominguez CA; Carlström KE; Zhang X-M; Al Nimer F; Lindblom RPF; Ortlieb Guerreiro-Cacais A; Piehl F
Article: NEUROBIOLOGY OF DISEASE. 2014;71:220-233

Acute treatment with valproic acid and l-thyroxine ameliorates clinical signs of experimental autoimmune encephalomyelitis and prevents brain pathology in DA rats.

Castelo-Branco G; Stridh P; Guerreiro-Cacais AO; Adzemovic MZ; Falcão AM; Marta M; Berglund R; Gillett A; Hamza KH; Lassmann H; Hermanson O; Jagodic M
Article: GENES AND IMMUNITY. 2014;15(7):457-465

The multiple sclerosis risk gene IL22RA2 contributes to a more severe murine autoimmune neuroinflammation.

Laaksonen H; Guerreiro-Cacais AO; Adzemovic MZ; Parsa R; Zeitelhofer M; Jagodic M; Olsson T
Article: GENES AND IMMUNITY. 2013;14(7):409-419

Anti-MOG antibodies are under polygenic regulation with the most significant control coming from the C-type lectin-like gene locus.

Flytzani S; Stridh P; Guerreiro-Cacais AO; Marta M; Hedreul MT; Jagodic M; Olsson T
Article: NATURE GENETICS. 2013;45(7):767-775

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.

Rat Genome Sequencing and Mapping Consortium; Baud A; Hermsen R; Guryev V; Stridh P; Graham D; McBride MW; Foroud T; Calderari S; Diez M; Ockinger J; Beyeen AD; Gillett A; Abdelmagid N; Guerreiro-Cacais AO; Jagodic M; Tuncel J; Norin U; Beattie E; Huynh N; Miller WH; Koller DL; Alam I; Falak S; Osborne-Pellegrin M; Martinez-Membrives E; Canete T; Blazquez G; Vicens-Costa E; Mont-Cardona C; Diaz-Moran S; Tobena A; Hummel O; Zelenika D; Saar K; Patone G; Bauerfeind A; Bihoreau M-T; Heinig M; Lee Y-A; Rintisch C; Schulz H; Wheeler DA; Worley KC; Muzny DM; Gibbs RA; Lathrop M; Lansu N; Toonen P; Ruzius FP; de Bruijn E; Hauser H; Adams DJ; Keane T; Atanur SS; Aitman TJ; Flicek P; Malinauskas T; Jones EY; Ekman D; Lopez-Aumatell R; Dominiczak AF; Johannesson M; Holmdahl R; Olsson T; Gauguier D; Hubner N; Fernandez-Teruel A; Cuppen E; Mott R; Flint J
Article: BRAIN BEHAVIOR AND IMMUNITY. 2013;27(1):109-122

Strain influences on inflammatory pathway activation, cell infiltration and complement cascade after traumatic brain injury in the rat.

Al Nimer F; Lindblom R; Ström M; Guerreiro-Cacais AO; Parsa R; Aeinehband S; Mathiesen T; Lidman O; Piehl F
Article: PLOS PATHOGENS. 2012;8(6):e1002753

The calcitonin receptor gene is a candidate for regulation of susceptibility to herpes simplex type 1 neuronal infection leading to encephalitis in rat.

Abdelmagid N; Bereczky-Veress B; Guerreiro-Cacais AO; Bergman P; Luhr KM; Bergström T; Sköldenberg B; Piehl F; Olsson T; Diez M
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2012;16(1):129-141

Syntaxin 11 marks a distinct intracellular compartment recruited to the immunological synapse of NK cells to colocalize with cytotoxic granules.

Dabrazhynetskaya A; Ma J; Guerreiro-Cacais AO; Arany Z; Rudd E; Henter J-I; Karre K; Levitskaya J; Levitsky V
Article: PLOS PATHOGENS. 2007;3(6):e80-834

A molecular link between malaria and Epstein-Barr virus reactivation.

Chêne A; Donati D; Guerreiro-Cacais AO; Levitsky V; Chen Q; Falk KI; Orem J; Kironde F; Wahlgren M; Bejarano MT
Article: JOURNAL OF VIROLOGY. 2007;81(3):1390-1400

Inhibition of heavy chain and beta2-microglobulin synthesis as a mechanism of major histocompatibility complex class I downregulation during Epstein-Barr virus replication.

Guerreiro-Cacais AO; Uzunel M; Levitskaya J; Levitsky V
Article: JOURNAL OF GENERAL VIROLOGY. 2004;85(Pt 10):2767-2778

Capacity of Epstein-Barr virus to infect monocytes and inhibit their development into dendritic cells is affected by the cell type supporting virus replication.

Guerreiro-Cacais AO; Li L; Donati D; Bejarano MT; Morgan A; Masucci MG; Hutt-Fletcher L; Levitsky V
Article: BRAZILIAN JOURNAL OF MICROBIOLOGY. 2001;32(2):141-143

Production of xylan-degrading enzymes by a Trichoderma harzianum strain

Cacais AOG; Silveira FQD; Ferreira EXF
Article: BIOTECHNOLOGY PROGRESS. 2000;16(3):522-524

The production of hemicellulases by aerobic fungi on medium containing residues of banana plant as substrate.

Medeiros RG; Soffner ML; Thomé JA; Cacais AO; Estelles RS; Salles BC; Ferreira HM; Lucena Neto SA; Silva FG; Filho EX
Article: BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH. 1999;32(8):947-952

Hydrolysis of xylans by enzyme systems from solid cultures of Trichoderma harzianum strains.

Silveira FQ; Ximenes FA; Cacais AO; Milagres AM; Medeiros CL; Puls J; Filho EX
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Editorial comment: NATURE REVIEWS IMMUNOLOGY. 2022;22(2):74

A pan-cancer signature for dysfunctional T cells.

Ruffin N; Guerreiro-Cacais AO
Letter: EXPERIMENTAL DERMATOLOGY. 2017;26(5):444-446

IL-22 binding protein regulates murine skin inflammation.

Lindahl H; Martini E; Brauner S; Nikamo P; Gallais Serezal I; Guerreiro-Cacais AO; Jagodic M; Eidsmo L; Ståhle M; Olsson T
Review: JOURNAL OF INFLAMMATION RESEARCH. 2015;8:211-225

Translational utility of experimental autoimmune encephalomyelitis: recent developments.

Guerreiro-Cacais AO; Laaksonen H; Flytzani S; N'diaye M; Olsson T; Jagodic M

Anställningar

Senior Forskningsspecialist, Klinisk neurovetenskap, Karolinska Institutet, 2022-

Examina och utbildning

Docent, Immunologi, Karolinska Institutet, 2024
MEDICINE DOKTORSEXAMEN, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2008

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