Epidemiology: Diet, contaminants and health – Agneta Åkesson's research group

We perform epidemiological research with the aim to advance knowledge on disease etiology and prevention, within a broad range of public health-related outcomes. Large focus lays on the link between diet, lifestyle, and health, also including aspects of sustainability and consequences of contaminant exposure via food and drinking water. We utilize extensive cohort-, biomarker-, omics-, and health register data, and perform Mendelian randomization studies.

Part of the Institute of Environmental Medicine

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Members and contact

Publications

Selected publications

Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2023;115(12):1597-1604

Disinfection by-products in drinking water and risk of colorectal cancer: a population-based cohort study.

Helte E; Säve-Söderbergh M; Larsson SC; Martling A; Åkesson A
Article: JAMA NETWORK OPEN. 2023;6(9):e2333347

Blood Levels of Organochlorine Contaminants Mixtures and Cardiovascular Disease.

Donat-Vargas C; Schillemans T; Kiviranta H; Rantakokko P; de Faire U; Arrebola JP; Wolk A; Leander K; Åkesson A
Article: JOURNAL OF INTERNAL MEDICINE. 2023;294(3):358-369

Urinary phosphate is associated with cardiovascular disease incidence.

Donat-Vargas C; Guallar-Castillon P; Nyström J; Larsson SC; Kippler M; Vahter M; Faxén-Irving G; Michaelsson K; Wolk A; Stenvinkel P; Åkesson A
Journal article: EFSA SUPPORTING PUBLICATIONS. 2023;20(5)

Preparatory work for the update of the tolerable upper intake levels for folic acid/folate

Åkesson A; Söderlund F; Bärebring L; Christensen JJ; Olsen T; Witthöft C
Review: FOOD & NUTRITION RESEARCH. 2023;67

Nuts and seeds consumption and risk of cardiovascular disease, type 2 diabetes and their risk factors: a systematic review and meta-analysis.

Arnesen EK; Thorisdottir B; Bärebring L; Söderlund F; Nwaru BI; Spielau U; Dierkes J; Ramel A; Lamberg-Allardt C; Åkesson A
Article: JOURNAL OF CLEANER PRODUCTION. 2022;373:133949

Dietary environmental impacts relative to planetary boundaries for six environmental indicators-A population-based study

Hallstrom E; Davis J; Hakansson N; Ahlgren S; Akesson A; Wolk A; Sonesson U
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2022;116(4):1091-1100

Calcium and magnesium in drinking water and risk of myocardial infarction and stroke-a population-based cohort study.

Helte E; Säve-Söderbergh M; Larsson SC; Åkesson A
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2022;130(3):37007

Per- and Polyfluoroalkyl Substances and Risk of Myocardial Infarction and Stroke: A Nested Case-Control Study in Sweden.

Schillemans T; Donat-Vargas C; Lindh CH; de Faire U; Wolk A; Leander K; Åkesson A
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2021;129(9):97012

Drinking Water Disinfection by-Products and Congenital Malformations: A Nationwide Register-Based Prospective Study.

Säve-Söderbergh M; Toljander J; Donat-Vargas C; Åkesson A
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2021;129(4):47005

Fluoride in Drinking Water, Diet, and Urine in Relation to Bone Mineral Density and Fracture Incidence in Postmenopausal Women.

Helte E; Donat Vargas C; Kippler M; Wolk A; Michaëlsson K; Åkesson A
Article: JOURNAL OF INTERNAL MEDICINE. 2020;287(2):197-209

Cardiovascular and cancer mortality in relation to dietary polychlorinated biphenyls and marine polyunsaturated fatty acids: a nutritional-toxicological aspect of fish consumption.

Donat-Vargas C; Bellavia A; Berglund M; Glynn A; Wolk A; Åkesson A
Article: ENVIRONMENT INTERNATIONAL. 2019;123:390-398

Perfluoroalkyl substances and risk of type II diabetes: A prospective nested case-control study.

Donat-Vargas C; Bergdahl IA; Tornevi A; Wennberg M; Sommar J; Kiviranta H; Koponen J; Rolandsson O; Åkesson A
Article: HYPERTENSION. 2018;71(6):1258-1268

Persistent Organochlorine Pollutants in Plasma, Blood Pressure, and Hypertension in a Longitudinal Study.

Donat-Vargas C; Åkesson A; Tornevi A; Wennberg M; Sommar J; Kiviranta H; Rantakokko P; Bergdahl IA
Article: NUTRIENTS. 2017;9(12):E1355-1355

Risks and Benefits of Increased Nut Consumption: Cardiovascular Health Benefits Outweigh the Burden of Carcinogenic Effects Attributed to Aflatoxin B₁ Exposure.

Eneroth H; Wallin S; Leander K; Nilsson Sommar J; Åkesson A
Article: ADVANCES IN NUTRITION. 2017;8(5):652-678

Perspective: An Extension of the STROBE Statement for Observational Studies in Nutritional Epidemiology (STROBE-nut): Explanation and Elaboration.

Hörnell A; Berg C; Forsum E; Larsson C; Sonestedt E; Åkesson A; Lachat C; Hawwash D; Kolsteren P; Byrnes G; De Keyzer W; Van Camp J; Cade JE; Greenwood DC; Slimani N; Cevallos M; Egger M; Huybrechts I; Wirfält E
Article: EUROPEAN JOURNAL OF CANCER. 2017;72:137-143

Dietary polychlorinated biphenyls, long-chain n-3 polyunsaturated fatty acids and incidence of malignant melanoma.

Donat-Vargas C; Berglund M; Glynn A; Wolk A; Åkesson A
Review: PLOS MEDICINE. 2016;13(6):e1002036

Strengthening the Reporting of Observational Studies in Epidemiology-Nutritional Epidemiology (STROBE-nut): An Extension of the STROBE Statement.

Lachat C; Hawwash D; Ocké MC; Berg C; Forsum E; Hörnell A; Larsson C; Sonestedt E; Wirfält E; Åkesson A; Kolsteren P; Byrnes G; De Keyzer W; Van Camp J; Cade JE; Slimani N; Cevallos M; Egger M; Huybrechts I

Funding

Funders

Per and polyfluorated substances and the risk of infections

Swedish Research Council for Environment Agricultural Sciences and Spatial Planning
Exposure to contaminants via food and drinking water – potentially overlooked modifiable risk factors in chronic disease development

Swedish Research Council
Drinking water and public health: the importance and handling of drinking water-related exposures in Sweden

Swedish Research Council for Environment Agricultural Sciences and Spatial Planning
Coronary heart disease and stroke - is exposure to environmental contaminants an overlooked modifiable risk factor?

Swedish Research Council
Prolonged exposure to drinking water purification by-products and risk of bladder and bowel cancer

Swedish Cancer Society
An interdisciplinary evaluation of combined health risks related to drinking water consumption for children and pregnant women

Swedish Research Council for Environment Agricultural Sciences and Spatial Planning

Members and contact

Group leader

Agneta Åkesson
Professor | Docent

Telephone +46852487542

E-mail agneta.akesson@ki.se

All members of the group

Carolina Donat Vargas
Affiliated to Research

E-mail carolina.donat.vargas@ki.se
Maximilian Flato
External Student | Affiliated to Research

E-mail maximilian.flato@ki.se
Emilie Helte
Phd Student

E-mail emilie.helte@ki.se
Niclas Håkansson
Researcher

Telephone +46852487080

E-mail niclas.hakansson@ki.se
Ana Rodrigues
Affiliated to Research

E-mail ana.rodrigues@ki.se
Tessa Schillemans
Postdoctoral Researcher

E-mail tessa.schillemans@ki.se
Melle Säve-Söderbergh
Affiliated to Research

E-mail melle.save-soderbergh@ki.se
Fredrik Söderlund
Phd Student

E-mail fredrik.soderlund@ki.se
Ulf de Faire
Professor Emeritus/Emerita

Telephone +46852487093

E-mail ulf.defaire@ki.se
Agneta Åkesson
Professor | Docent

Telephone +46852487542

E-mail agneta.akesson@ki.se

Other people connected to the group

Yuan, Shuai
Wolk, Alicja
Ibsen, Daniel
Nannsen, Anne
Kaluza, Joanna

Visiting address

Karolinska Institute, Institute of Environmental Medicine, Nobels väg 13, Stockholm, Sweden

Postal address

Karolinska Institutet, Institute of Environmental Medicine, Box 210, Stockholm, 17177, Sweden