Dr. Sullivan is a Professor of Psychiatric Genetics at the Karolinska Institute in the Department of Medical Epidemiology and Biostatistics. He is also the Yeargan Distinguished Professor in the Department of Genetics and Psychiatry at the University of North Carolina at Chapel Hill. His lab investigates the molecular genetics of schizophrenia, major depressive disorder (including post-partum depression), eating disorders, and autism. Dr. Sullivan is a founder and the lead principal investigator of the Psychiatric Genomics Consortium, the largest consortium in the history of psychiatry. He is involved in a wide range of genomic studies of human diseases and has multiple NIH grants. At Karolinska Institutet Dr Sullivan is responsible for the KI Psychiatric Genomics Institute - a systematic program established to evaluate the epidemiological, molecular, and cellular effects of genetic risk loci for psychiatric disorders. Dr. Sullivan has published over 320 papers and 40 reviews/chapters.
- Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?
Biol. Psychiatry 2014 Oct;76(7):510-2
- A mega-analysis of genome-wide association studies for major depressive disorder.
Mol. Psychiatry 2013 Apr;18(4):497-511
- Biological insights from 108 schizophrenia-associated genetic loci.
Nature 2014 Jul;511(7510):421-7
- Puzzling over schizophrenia: schizophrenia as a pathway disease.
Nat. Med. 2012 Feb;18(2):210-1
- Genetic architectures of psychiatric disorders: the emerging picture and its implications.
Nat. Rev. Genet. 2012 Jul;13(8):537-51
- Heritability and genomics of gene expression in peripheral blood.
Nat. Genet. 2014 May;46(5):430-7
Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia
Nature neuroscience 2016;19(11):1433-1441
Integrative approaches for large-scale transcriptome-wide association studies
Nature genetics 2016;48(3):245-52
Modeling psychiatric disorders: from genomic findings to cellular phenotypes
Molecular psychiatry 2016;21(9):1167-79
One CNV Discordance in NRXN1 Observed Upon Genome-wide Screening in 38 Pairs of Adult Healthy Monozygotic Twins
Twin research and human genetics : the official journal of the International Society for Twin Studies 2016;19(2):97-103
Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach
The lancet. Psychiatry 2016;3(4):350-7
Quantifying prion disease penetrance using large population control cohorts
Science translational medicine 2016;8(322):322ra9-
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders
Nature neuroscience 2016;19(4):571-7
Ultra-rare disruptive and damaging mutations influence educational attainment in the general population
Nature neuroscience 2016;19(12):1563-1565
What Next in Schizophrenia Genetics for the Psychiatric Genomics Consortium?
Schizophrenia bulletin 2016;42(3):538-41
Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use
Alcoholism, clinical and experimental research 2015;39(8):1396-405
Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case-control sample of schizophrenia
Translational psychiatry 2015;5():e656-
Genetics of disease: Associations with depression
Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood
Twin research and human genetics : the official journal of the International Society for Twin Studies 2015;18(4):335-47
Meta-analysis of the heritability of human traits based on fifty years of twin studies
Nature genetics 2015;47(7):702-9
Multiple SNP Set Analysis for Genome-Wide Association Studies Through Bayesian Latent Variable Selection
Genetic epidemiology 2015;39(8):664-77
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis
International journal of epidemiology 2015;44(5):1706-21
Schizophrenia: Hope on the Horizon
Cerebrum : the Dana forum on brain science 2015;2015():-
The Mouse Universal Genotyping Array: From Substrains to Subspecies
G3 (Bethesda, Md.) 2015;6(2):263-79
The PsychENCODE project
Nature neuroscience 2015;18(12):1707-12