I am a Professor in Cancer Epidemiology and since 2011 Deputy chair at the Department of Medical Epidemiology and Biostatistics. My research focuses on the etiology of breast cancer in a very broad sense.
- PhD in Molecular Epidemiology - Karolinska Institutet, Stockholm, Sweden
- MSci in Nuclear Engineering - Faculty of Nuclear Science and Physical Engineering, Czech Technical University, Prague, Czech Republic
Main research focus: Breast cancer prognosis
There are both host (patient) and tumor characteristics that define breast cancer prognosis, as well as treatment response and complications. The central concept of my research agenda is to acquire a comprehensive picture of the determinants of prognosis in breast cancer patients using high quality epidemiological studies, molecular data and state-of-the-art analyses to combine information on patient and tumor determinants. The main aims of my current research are the following:
- To determine genetic variants associated with prognosis of breast cancer (inherited alterations)
- To identify novel breast- tumor specific markers for disease progression (somatic alterations)
- To study the long-term breast cancer prognosis as well as the panorama of diseases in breast cancer survivors.
Other research interests
- Mammographic screening and interval breast cancer
- Breast cancer risk and prevention
- Better understanding of mammographic density and implementation for clinical use
- Genetic studies on (any) cancer
- Twin studies on (any) cancer
- Family studies on (any) cancer including development of statistical methods
- Epidemiological Methods
Current supervision of PhD students
Current post docs
Current research grants (as PI)
My research work is supported by Swedish Research Council (Vetenskapsrådet), FORTE, Cancerföreningen, Swedish Cancer Society (Cancerfonden), Stockholm County Council (SLL/ALF).
Holm J, Li J, Darabi H, Eklund M, Eriksson M, Humphreys K, Hall P and Czene K. Associations of breast cancer risk prediction tools with tumor characteristics and metastasis. Journal of Clinical Oncology. 2015. [epub ahead of print]
Predictors of Discontinuation of Adjuvant Hormone Therapy in Patients With Breast Cancer.
J. Clin. Oncol. 2015 Jul;33(20):2262-9
Risk factors and tumor characteristics of interval cancers by mammographic density.
J. Clin. Oncol. 2015 Mar;33(9):1030-7
Volumetric mammographic density: heritability and association with breast cancer susceptibility loci.
J. Natl. Cancer Inst. 2014 Dec;106(12):
Academic honours, awards and prizes
In 2007 I recieved the "Young Investigator Award" a 6-year full research position from the Swedish Cancer Society.