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Agneta Nordberg

Professor, senior

Visiting address : Novum Pl 5, Hälsovägen7/Blickagången 6 141 57 Huddinge, Sweden
Postal address : Department of Neurobiology, Care Sciences and Society (NVS), H1, Division of Translational Alzheimer Neurobiology, Novum Pl 5, Blickagången 6/Hälsovägen 7 141 57 Huddinge, Sweden
Delivery address : Hälsovägen 7 141 57 Huddinge, Sweden

Publications

Amyloid tracers binding sites in autosomal dominant and sporadic Alzheimer's disease
Ni R, Gillberg Pg, Bogdanovic N, Viitanen M, Myllykangas L, Nennesmo I, et al
Alzheimer's & dementia : the journal of the Alzheimer's Association 2016;():-

Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs
Kumar R, Nordberg A, Darreh-shori T
Brain : a journal of neurology 2016;139(Pt 1):174-92

Comparison of Early-Phase 11C-Deuterium-l-Deprenyl and 11C-Pittsburgh Compound B PET for Assessing Brain Perfusion in Alzheimer Disease
Rodriguez-vieitez E, Carter Sf, Chiotis K, Saint-aubert L, Leuzy A, Schöll M, et al
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2016;57(7):1071-7

Defeating Alzheimer's disease and other dementias: a priority for European science and society
Winblad B, Amouyel P, Andrieu S, Ballard C, Brayne C, Brodaty H, et al
The Lancet. Neurology 2016;15(5):455-532

Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer's disease
Rodriguez-vieitez E, Saint-aubert L, Carter Sf, Almkvist O, Farid K, Schöll M, et al
Brain : a journal of neurology 2016;139(Pt 3):922-36

Imaging in-vivo tau pathology in Alzheimer's disease with THK5317 PET in a multimodal paradigm
Chiotis K, Saint-aubert L, Savitcheva I, Jelic V, Andersen P, Jonasson M, et al
European journal of nuclear medicine and molecular imaging 2016;43(9):1686-99

Imaging β-amyloid using [(18)F]flutemetamol positron emission tomography: from dosimetry to clinical diagnosis
Heurling K, Leuzy A, Zimmer Er, Lubberink M, Nordberg A
European journal of nuclear medicine and molecular imaging 2016;43(2):362-73

Pittsburgh compound B imaging and cerebrospinal fluid amyloid-β in a multicentre European memory clinic study
Leuzy A, Chiotis K, Hasselbalch Sg, Rinne Jo, De Mendonça A, Otto M, et al
Brain : a journal of neurology 2016;139(Pt 9):2540-53

Regional tau deposition measured by [F-18]THK5317 positron emission tomography is associated to cognition via glucose metabolism in Alzheimer's disease
Saint-aubert L, Almkvist O, Chiotis K, Almeida R, Wall A, Nordberg A
ALZHEIMERS RESEARCH & THERAPY 2016;:38-

Targeted delivery of nerve growth factor to the cholinergic basal forebrain of Alzheimer's disease patients: application of a second-generation encapsulated cell biodelivery device
Eyjolfsdottir H, Eriksdotter M, Linderoth B, Lind G, Juliusson B, Kusk P, et al
Alzheimer's research & therapy 2016;8(1):30-

The Culprit Is in the Cave: The Core Sites Explain the Binding Profiles of Amyloid-Specific Tracers
Murugan Na, Halldin C, Nordberg A, Långström B, Ågren H
The journal of physical chemistry letters 2016;7(17):3313-21

Theoretical study of the binding profile of an allosteric modulator NS-1738 with a chimera structure of the α7 nicotinic acetylcholine receptor
Kuang G, Wang X, Halldin C, Nordberg A, Långström B, Ågren H, et al
Physical chemistry chemical physics : PCCP 2016;18(40):28003-28009

Tracer Kinetic Analysis of (S)-¹⁸F-THK5117 as a PET Tracer for Assessing Tau Pathology
Jonasson M, Wall A, Chiotis K, Saint-aubert L, Wilking H, Sprycha M, et al
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2016;57(4):574-81

Use of amyloid-PET to determine cutpoints for CSF markers: A multicenter study
Zwan Md, Rinne Jo, Hasselbalch Sg, Nordberg A, Lleó A, Herukka Sk, et al
Neurology 2016;86(1):50-8

Amyloid PET in European and North American cohorts; and exploring age as a limit to clinical use of amyloid imaging
Chiotis K, Carter Sf, Farid K, Savitcheva I, Nordberg A, Diagnostic Molecular Imaging (dimi) Network And The Alzheimer’s Disease Neuroimaging Initiative
European journal of nuclear medicine and molecular imaging 2015;42(10):1492-506

Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study
Rodriguez-vieitez E, Ni R, Gulyás B, Tóth M, Häggkvist J, Halldin C, et al
European journal of nuclear medicine and molecular imaging 2015;42(7):1119-32

Case Report of Complex Amyotrophic Lateral Sclerosis with Cognitive Impairment and Cortical Amyloid Deposition
Farid K, Carter Sf, Rodriguez-vieitez E, Almkvist O, Andersen P, Wall A, et al
Journal of Alzheimer's disease : JAD 2015;47(3):661-7

Changes in CSF cholinergic biomarkers in response to cell therapy with NGF in patients with Alzheimer's disease
Karami A, Eyjolfsdottir H, Vijayaraghavan S, Lind G, Almqvist P, Kadir A, et al
Alzheimer's & dementia : the journal of the Alzheimer's Association 2015;11(11):1316-28

Concordance and Diagnostic Accuracy of [11C]PIB PET and Cerebrospinal Fluid Biomarkers in a Sample of Patients with Mild Cognitive Impairment and Alzheimer's Disease
Leuzy A, Carter Sf, Chiotis K, Almkvist O, Wall A, Nordberg A
Journal of Alzheimer's disease : JAD 2015;45(4):1077-88

Correlations between Alzheimer's Disease Cerebrospinal Fluid Biomarkers and Cerebral Glucose Metabolism after 12 Months of Phenserine Treatment
Nordberg A, Kadir A, Andreasen N, Almkvist O, Wall A, Långström B, et al
Journal of Alzheimer's disease : JAD 2015;47(3):691-704

Degree of abnormality is associated with rate of change in measures of beta-amyloid, glucose metabolism and cognition in an autopsy-verified Alzheimer's disease case
Almkvist O, Kadir A, Nordberg A
Neurocase 2015;21(6):738-47

Early astrocytosis in autosomal dominant Alzheimer's disease measured in vivo by multi-tracer positron emission tomography
Schöll M, Carter Sf, Westman E, Rodriguez-vieitez E, Almkvist O, Thordardottir S, et al
Scientific reports 2015;5():16404-

First administration of the Fc-attenuated anti-β amyloid antibody GSK933776 to patients with mild Alzheimer's disease: a randomized, placebo-controlled study
Andreasen N, Simeoni M, Ostlund H, Lisjo Pi, Fladby T, Loercher Ae, et al
PloS one 2015;10(3):e0098153-

Glial Asthenia and Functional Paralysis: A New Perspective on Neurodegeneration and Alzheimer's Disease
Verkhratsky A, Marutle A, Rodriguez-arellano Jj, Nordberg A
NEUROSCIENTIST 2015;21(5):552-568

Investigation of the Binding Profiles of AZD2184 and Thioflavin T with Amyloid-β(1-42) Fibril by Molecular Docking and Molecular Dynamics Methods
Kuang G, Murugan Na, Tu Y, Nordberg A, Ågren H
The journal of physical chemistry. B 2015;119(35):11560-7

Mild cognitive impairment with suspected nonamyloid pathology (SNAP): Prediction of progression
Caroli A, Prestia A, Galluzzi S, Ferrari C, Van Der Flier Wm, Ossenkoppele R, et al
Neurology 2015;84(5):508-15

Neural Stem Cell Transplant-Induced Effect on Neurogenesis and Cognition in Alzheimer Tg2576 Mice Is Inhibited by Concomitant Treatment with Amyloid-Lowering or Cholinergic α7 Nicotinic Receptor Drugs
Lilja Am, Malmsten L, Röjdner J, Voytenko L, Verkhratsky A, Ögren So, et al
Neural plasticity 2015;2015():370432-

Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer's disease patients and control subjects
Varrone A, Oikonen V, Forsberg A, Joutsa J, Takano A, Solin O, et al
European journal of nuclear medicine and molecular imaging 2015;42(3):438-46

Prediction of AD dementia by biomarkers following the NIA-AA and IWG diagnostic criteria in MCI patients from three European memory clinics
Prestia A, Caroli A, Wade Sk, Van Der Flier Wm, Ossenkoppele R, Van Berckel B, et al
Alzheimer's & dementia : the journal of the Alzheimer's Association 2015;11(10):1191-201

Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis
Ossenkoppele R, Jansen Wj, Rabinovici Gd, Knol Dl, Van Der Flier Wm, Van Berckel Bn, et al
JAMA 2015;313(19):1939-49

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis
Jansen Wj, Ossenkoppele R, Knol Dl, Tijms Bm, Scheltens P, Verhey Fr, et al
JAMA 2015;313(19):1924-38

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey
Bocchetta M, Galluzzi S, Kehoe Pg, Aguera E, Bernabei R, Bullock R, et al
Alzheimer's & dementia : the journal of the Alzheimer's Association 2015;11(2):195-206.e1

Visualization of regional tau deposits using (3)H-THK5117 in Alzheimer brain tissue
Lemoine L, Saint-aubert L, Marutle A, Antoni G, Eriksson Jp, Ghetti B, et al
Acta neuropathologica communications 2015;3():40-

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
Dubois B, Feldman Hh, Jacova C, Hampel H, Molinuevo Jl, Blennow K, et al
The Lancet. Neurology 2014;13(6):614-29

Astrocytosis measured by ¹¹C-deprenyl PET correlates with decrease in gray matter density in the parahippocampus of prodromal Alzheimer's patients
Choo Il, Carter Sf, Schöll Ml, Nordberg A
European journal of nuclear medicine and molecular imaging 2014;41(11):2120-6

Harmonized diagnostic criteria for Alzheimer's disease: recommendations
Morris Jc, Blennow K, Froelich L, Nordberg A, Soininen H, Waldemar G, et al
Journal of internal medicine 2014;275(3):204-13

Molecular imaging in sporadic Alzheimer's disease populations and those genetically at risk
Nordberg A
Neuro-degenerative diseases 2014;13(2-3):160-2

Pharmacodynamics of cholinesterase inhibitors suggests add-on therapy with a low-dose carbamylating inhibitor in patients on long-term treatment with rapidly reversible inhibitors
Darreh-shori T, Hosseini Sm, Nordberg A
Journal of Alzheimer's disease : JAD 2014;39(2):423-40

Promising two-photon probes for in vivo detection of β amyloid deposits
Murugan Na, Zaleśny R, Kongsted J, Nordberg A, Ågren H
Chemical communications (Cambridge, England) 2014;50(79):11694-7

³H-deprenyl and ³H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain
Marutle A, Gillberg Pg, Bergfors A, Yu W, Ni R, Nennesmo I, et al
Journal of neuroinflammation 2013;10():90-

A European multicentre PET study of fibrillar amyloid in Alzheimer's disease
Nordberg A, Carter Sf, Rinne J, Drzezga A, Brooks Dj, Vandenberghe R, et al
European journal of nuclear medicine and molecular imaging 2013;40(1):104-14

Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice following modulation of brain amyloid-β levels
Lilja Am, Röjdner J, Mustafiz T, Thomé Cm, Storelli E, Gonzalez D, et al
PloS one 2013;8(3):e58752-

Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue
Ni R, Gillberg Pg, Bergfors A, Marutle A, Nordberg A
Brain : a journal of neurology 2013;136(Pt 7):2217-27

A review of butyrylcholinesterase as a therapeutic target in the treatment of Alzheimer's disease
Nordberg A, Ballard C, Bullock R, Darreh-shori T, Somogyi M
The primary care companion for CNS disorders 2013;15(2):-

Combination of 18F-FDG PET and cerebrospinal fluid biomarkers as a better predictor of the progression to Alzheimer's disease in mild cognitive impairment patients
Choo Ih, Ni R, Schöll M, Wall A, Almkvist O, Nordberg A
Journal of Alzheimer's disease : JAD 2013;33(4):929-39

Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET
Edison P, Carter Sf, Rinne Jo, Gelosa G, Herholz K, Nordberg A, et al
NeuroImage 2013;70():423-33

Functional variability in butyrylcholinesterase activity regulates intrathecal cytokine and astroglial biomarker profiles in patients with Alzheimer's disease
Darreh-shori T, Vijayaraghavan S, Aeinehband S, Piehl F, Lindblom Rp, Nilsson B, et al
Neurobiology of aging 2013;34(11):2465-81

Imaging markers for Alzheimer disease: which vs how
Frisoni Gb, Bocchetta M, Chételat G, Rabinovici Gd, De Leon Mj, Kaye J, et al
Neurology 2013;81(5):487-500

Modulation of α7 nicotinic acetylcholine receptor and fibrillar amyloid-β interactions in Alzheimer's disease brain
Ni R, Marutle A, Nordberg A
Journal of Alzheimer's disease : JAD 2013;33(3):841-51

Neurotrophic and neuroprotective actions of (-)- and (+)-phenserine, candidate drugs for Alzheimer's disease
Lilja Am, Luo Y, Yu Qs, Röjdner J, Li Y, Marini Am, et al
PloS one 2013;8(1):e54887-

Prediction of dementia in MCI patients based on core diagnostic markers for Alzheimer disease
Prestia A, Caroli A, Van Der Flier Wm, Ossenkoppele R, Van Berckel B, Barkhof F, et al
Neurology 2013;80(11):1048-56

Apolipoprotein epsilon 4 Modulates Phenotype of Butyrylcholinesterase in CSF of Patients with Alzheimer's Disease
Darreh-shori T, Siawesh M, Mousavi M, Andreasen N, Nordberg A
JOURNAL OF ALZHEIMERS DISEASE 2012;28(2):443-58

Different beta-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity
Bao Fx, Wicklund L, Lacor Pn, Klein Wl, Nordberg A, Marutle A
NEUROBIOLOGY OF AGING 2012;33(4):825.e1-13

Dynamic changes in PET amyloid and FDG imaging at different stages of Alzheimer's disease
Kadir A, Almkvist O, Forsberg A, Wall A, Engler H, Langstrom B, et al
NEUROBIOLOGY OF AGING 2012;33(1):198.e1-14

Encapsulated Cell Biodelivery of Nerve Growth Factor to the Basal Forebrain in Patients with Alzheimer's Disease
Eriksdotter-jonhagen M, Linderoth B, Lind G, Aladellie L, Almkvist O, Andreasen N, et al
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 2012;33(1):18-28

Evidence for Astrocytosis in Prodromal Alzheimer Disease Provided by C-11-Deuterium-L-Deprenyl: A Multitracer PET Paradigm Combining C-11-Pittsburgh Compound B and F-18-FDG
Carter Sf, Scholl M, Almkvist O, Wall A, Engler H, Langstrom B, et al
JOURNAL OF NUCLEAR MEDICINE 2012;53(1):37-46

Low PiB PET retention in presence of pathologic CSF biomarkers in Arctic APP mutation carriers
Schöll M, Wall A, Thordardottir S, Ferreira D, Bogdanovic N, Långström B, et al
Neurology 2012;79(3):229-36

Neuroprotection and neuroregeneration in Alzheimer's disease
Sugaya K, Youdim Mb, Nordberg A, Rao Ks
International journal of Alzheimer's disease 2012;2012():864138-

The use of PIB-PET as a dual pathological and functional biomarker in AD
Forsberg A, Engler H, Blomquist G, Langstrom B, Nordberg A
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2012;1822(3):380-5

Biomarkers for Alzheimer's disease therapeutic trials
Oxford Task Force Grp, Hampel H, Wilcock G, Andrieu S, Aisen P, Blennow K, et al
PROGRESS IN NEUROBIOLOGY 2011;95(4):579-93

Characterization of the Brain beta-Amyloid Isoform Pattern at Different Ages of Tg2576 Mice
Mustafiz T, Portelius E, Gustavsson Mk, Holtta M, Zetterberg H, Blennow K, et al
NEURODEGENERATIVE DISEASES 2011;8(5):352-63

Differential levels of apolipoprotein E and butyrylcholinesterase show strong association with pathological signs of Alzheimer's disease in the brain in vivo
Darreh-shori T, Forsberg A, Modiri N, Andreasen N, Blennow K, Kamil C, et al
NEUROBIOLOGY OF AGING 2011;32(12):2320.e15-32

Functional Interactions of Fibrillar and Oligomeric Amyloid-beta with Alpha7 Nicotinic Receptors in Alzheimer's Disease
Lilja Am, Porras O, Storelli E, Nordberg A, Marutle A
JOURNAL OF ALZHEIMERS DISEASE 2011;23(2):335-47

Glucose metabolism and PIB binding in carriers of a His163Tyr presenilin 1 mutation
Scholl M, Almkvist O, Axelman K, Stefanova E, Wall A, Westman E, et al
NEUROBIOLOGY OF AGING 2011;32(8):1388-99

Long-term Effects of Galantamine Treatment on Brain Functional Activities as Measured by PET in Alzheimer's Disease Patients
Keller C, Kadir A, Forsberg A, Porras O, Nordberg A
JOURNAL OF ALZHEIMERS DISEASE 2011;24(1):109-23

Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation
Shafaati M, Marutle A, Pettersson H, Lovgren-sandblom A, Olin M, Pikuleva I, et al
JOURNAL OF LIPID RESEARCH 2011;52(5):1004-10

Molecular imaging in Alzheimer's disease: new perspectives on biomarkers for early diagnosis and drug development
Nordberg A
Alzheimer's research & therapy 2011;3(6):34-

Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer's disease
Kadir A, Marutle A, Gonzalez D, Scholl M, Almkvist O, Mousavi M, et al
BRAIN 2011;:301-17

The apolipoprotein E epsilon 4 allele plays pathological roles in AD through high protein expression and interaction with butyrylcholinesterase
Darreh-shori T, Modiri N, Blennow K, Baza S, Kamil C, Ahmed H, et al
NEUROBIOLOGY OF AGING 2011;32(7):1236-48

Time Course of Glucose Metabolism in Relation to Cognitive Performance and Postmortem Neuropathology in Met146Val PSEN1 Mutation Carriers
Scholl M, Almkvist O, Bogdanovic N, Wall A, Langstrom B, Viitanen M, et al
JOURNAL OF ALZHEIMERS DISEASE 2011;24(3):495-506

Transgenic Mice as a Model for Alzheimer's Disease
Lithner Cu, Hedberg Mm, Nordberg A
CURRENT ALZHEIMER RESEARCH 2011;8(8):818-31

Amyloid Imaging in Early Detection of Alzheimer's Disease
Nordberg A
NEURODEGENERATIVE DISEASES 2010;7(1-3):136-8

beta-Amyloid 1-42 Oligomers Impair Function of Human Embryonic Stem Cell-Derived Forebrain Cholinergic Neurons
Wicklund L, Leao Rn, Stromberg Am, Mousavi M, Hovatta O, Nordberg A, et al
PLOS ONE 2010;5(12):e15600-

Effect of Huprine X on beta-Amyloid, Synaptophysin and alpha 7 Neuronal Nicotinic Acetylcholine Receptors in the Brain of 3xTg-AD and APPswe Transgenic Mice
Hedberg Mm, Clos Mv, Ratia M, Gonzalez D, Lithner Cu, Camps P, et al
NEURODEGENERATIVE DISEASES 2010;7(6):379-88

High PIB Retention in Alzheimer's Disease is an Early Event with Complex Relationship with CSF Biomarkers and Functional Parameters
Forsberg A, Almkvist O, Engler H, Wall A, Langstrom B, Nordberg A
CURRENT ALZHEIMER RESEARCH 2010;7(1):56-66

Neurotrophic factors promote cholinergic differentiation in human embryonic stem cell-derived neurons
Nilbratt M, Porras O, Marutle A, Hovatta O, Nordberg A
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2010;14(6B):1476-84

Pittsburgh Compound-B and Alzheimer's Disease Biomarkers in CSF, Plasma and Urine: An Exploratory Study
Gunnarsson Md, Lindau M, Wall A, Blennow K, Darreh-shori T, Basu S, et al
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 2010;29(3):204-12

Target-Specific PET Probes for Neurodegenerative Disorders Related to Dementia
Kadir A, Nordberg A
JOURNAL OF NUCLEAR MEDICINE 2010;51(9):1418-30

The use of PET in Alzheimer disease
Nordberg A, Rinne Jo, Kadir A, Langstrom B
NATURE REVIEWS NEUROLOGY 2010;6(2):78-87

A beta((25-35)) Attenuated SREBP Level in Nuclear Extracts of Serum-Deprived Human Neuroblastoma Cells
Kelicen P, Cincioglu M, Hizli F, Nordberg A
NEUROCHEMICAL RESEARCH 2009;34(5):845-50

[C-11]PIB-amyloid binding and levels of A beta 40 and A beta 42 in postmortem brain tissue from Alzheimer patients
Svedberg Mm, Hall H, Hellstrom-lindahl E, Estrada S, Guan Zz, Nordberg A, et al
NEUROCHEMISTRY INTERNATIONAL 2009;54(5-6):347-57

Different Cholinesterase Inhibitor Effects on CSF Cholinesterases in Alzheimer Patients
Nordberg A, Darreh-shori T, Peskind E, Soininen H, Mousavi M, Eagle G, et al
CURRENT ALZHEIMER RESEARCH 2009;6(1):4-14

Progression from mild cognitive impairment to Alzheimer's disease: effects of sex, butyrylcholinesterase genotype, and rivastigmine treatment
Ferris S, Nordberg A, Soininen H, Darreh-shori T, Lane R
PHARMACOGENETICS AND GENOMICS 2009;19(8):635-46

Safety of Lumbar Puncture Procedures in Patients with Alzheimer's Disease
Peskind E, Nordberg A, Darreh-shori T, Soininen H
CURRENT ALZHEIMER RESEARCH 2009;6(3):290-2

The future: new methods of imaging exploration in Alzheimer's disease
Nordberg A
Frontiers of neurology and neuroscience 2009;24():47-53

Age-dependent decline of neprilysin in Alzheimer's disease and normal brain: Inverse correlation with A beta levels
Hellstrom-lindahl E, Ravid R, Nordberg A
NEUROBIOLOGY OF AGING 2008;29(2):210-21

Amyloid imaging in Alzheimer's disease
Nordberg A
NEUROPSYCHOLOGIA 2008;46(6):1636-41

Amyloid plaque imaging in vivo: current achievement and future prospects
Nordberg A
European journal of nuclear medicine and molecular imaging 2008;35 Suppl 1():S46-50

[C-11]-PIB imaging in patients with Parkinson's disease: Preliminary results
Johansson A, Savitcheva I, Forsberg A, Engler H, Langstrom B, Nordberg A, et al
PARKINSONISM & RELATED DISORDERS 2008;14(4):345-7

Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease
Kadir A, Andreasen N, Almkvist O, Wall A, Forsberg A, Engler H, et al
ANNALS OF NEUROLOGY 2008;63(5):621-31

Inhibition of acetylcholinesterase in CSF versus brain assessed by C-11-PMP PET in AD patients treated with galantamine
Darreh-shori T, Kadir A, Almkvist O, Grut M, Wall A, Blomquist G, et al
NEUROBIOLOGY OF AGING 2008;29(2):168-84

In vivo amyloid imaging with PET in frontotemporal dementia
Engler H, Santillo Af, Wang Sx, Lindau M, Savitcheva I, Nordberg A, et al
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 2008;35(1):100-6

PET imaging of amyloid deposition in patients with mild cognitive impairment
Forsberg A, Engler H, Almkvist O, Blomquist G, Hagman G, Wall A, et al
NEUROBIOLOGY OF AGING 2008;29(10):1456-65

PET imaging of the in vivo brain acetylcholinesterase activity and nicotine binding in galantamine-treated patients with AD
Kadir A, Darreh-shori T, Almkvist O, Wall A, Grut M, Strandberg B, et al
NEUROBIOLOGY OF AGING 2008;29(8):1204-17

Synergistic effect of apolipoprotein E epsilon 4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease
Lane R, Feldman Hh, Meyer J, He Y, Ferris Sh, Nordberg A, et al
PHARMACOGENETICS AND GENOMICS 2008;18(4):289-98

Transgenic mice overexpressing human acetylcholinesterase and the Swedish amyloid precursor protein mutation: Effect of nicotine treatment
Hedberg Mm, Svedberg Mm, Mustafiz T, Yu Wf, Mousavi M, Guan Zz, et al
NEUROSCIENCE 2008;152(1):223-33

Unidirectional Influx and Net Accumulation of PIB
Blomquist G, Engler H, Nordberg A, Ringheim A, Wall A, Forsberg A, et al
The open neuroimaging journal 2008;2():114-25

Amyloid imaging in Alzheimer's disease
Nordberg A
CURRENT OPINION IN NEUROLOGY 2007;20(4):398-402

Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress
Celsi F, Svedberg M, Unger C, Cotman Cw, Carri Mt, Ottersen Op, et al
NEUROBIOLOGY OF DISEASE 2007;26(2):342-52

Changes in brain C-11-nicotine binding sites in patients with mild Alzheimer's disease following rivastigmine treatment as assessed by PET
Kadir A, Darreh-shori T, Almkvist O, Wall A, Langstrom B, Nordberg A
PSYCHOPHARMACOLOGY 2007;191(4):1005-14

Effects of statins on alpha 7 nicotine receptor, cholinesterase and alpha-form of secreted amyloid precursor peptide in SH-SY5Y
Roensch J, Crisby M, Nordberg A, Xiao Y, Zhang Lj, Guan Zz
NEUROCHEMISTRY INTERNATIONAL 2007;50(6):800-6

Modulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine
Marutle A, Ohmitsu M, Nilbratt M, Greig Nh, Nordberg A, Sugaya K
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2007;104(30):12506-11

Neurogenic neuroepithelial and radial glial cells generated from six human embryonic stem cell lines in serum-free suspension and adherent cultures
Nat R, Nilbratt M, Narkilahti S, Winblad B, Hovatta O, Nordberg A
GLIA 2007;55(4):385-99

Postnatal upregulation of alpha 4 and alpha 3 nicotinic receptor subunits in the brain of alpha 7 nicotinic receptor-deficient mice
Yu Wf, Guan Zz, Nordberg A
NEUROSCIENCE 2007;146(4):1618-28

Regulation of alpha- and beta-secretase activity by oxysterols: Cerebrosterol stimulates processing of APP via the alpha-secretase pathway
Famer D, Meaney S, Mousavi M, Nordberg A, Bjorkhem I, Crisby M
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2007;359(1):46-50

Retinoic acid and nerve growth factor induce differential regulation of nicotinic acetylcholine receptor subunit expression in SN56 cells
Nilbratt M, Friberg L, Mousavi M, Marutle A, Nordberg A
JOURNAL OF NEUROSCIENCE RESEARCH 2007;85(3):504-14

The consequences of reducing expression of the alpha 7 nicotinic receptor by RNA interference and of stimulating its activity with an alpha 7 agonist in SH-SY5Y cells indicate that this receptor plays a neuroprotective role in connection with the pathogenesis of Alzheimer's disease
Qi Xl, Nordberg A, Xiu J, Guan Zz
NEUROCHEMISTRY INTERNATIONAL 2007;51(6-7):377-83

[Administration of symptom-relieving drugs in Alzheimer disease is beneficial]
Nordberg A, Eriksdotter-jönhagen M, Garlind A, Grut M, Freund-levi Y, Cornelius C, et al
Lakartidningen 2006;103(6):369-71

Changes in the activity and protein levels of CSF acetylcholinesterases in relation to cognitive function of patients with mild Alzheimer's disease following chronic donepezil treatment
Darreh-shori T, Meurling L, Pettersson T, Hugosson K, Hellstrom-lindahl E, Andreasen N, et al
JOURNAL OF NEURAL TRANSMISSION 2006;113(11):1791-801

Differential CSF butyrylcholinesterase levels in Alzheimer's disease patients with the ApoE epsilon 4 allele, in relation to cognitive function and cerebral glucose metabolism
Darreh-shori T, Brimijoin S, Kadir A, Almkvist O, Nordberg A
NEUROBIOLOGY OF DISEASE 2006;24(2):326-33

Effect of subchronic treatment of memantine, galantamine, and nicotine in the brain of Tg2576 (APPswe) transgenic mice
Unger C, Svedberg Mm, Yu Wf, Hedberg Mm, Nordberg A
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2006;317(1):30-6

Emerging biology of the cholinergic system across the spectrum of Alzheimer's disease
Nordberg A
INTERNATIONAL PSYCHOGERIATRICS 2006;:S3-S16

Expression of the alpha 7, alpha 4 and alpha 3 nicotinic receptor subtype in the brain and adrenal medulla of transgenic mice carrying genes coding for human AChE and beta-amyloid
Mousavi M, Nordberg A
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE 2006;24(4):269-73

Feedback regulation of SREBP and aromatase in a beta(25-35)-supplemented human neuroblastoma cells
Kelicen P, Nordberg A
CELLULAR AND MOLECULAR NEUROBIOLOGY 2006;26(3):225-35

Influence of cholesterol and lovastatin on alpha-form of secreted amyloid precursor protein and expression of alpha 7 nicotinic receptor on astrocytes
Xiu J, Nordberg A, Qi X, Guan Zz
NEUROCHEMISTRY INTERNATIONAL 2006;49(5):459-65

Longitudinal PET evaluation of cerebral glucose metabolism in rivastigmine treated patients with mild Alzheimer's disease
Stefanova E, Wall A, Almkvist O, Nilsson A, Forsberg A, Langstrom B, et al
JOURNAL OF NEURAL TRANSMISSION 2006;113(2):205-18

Mechanisms behind the neuroprotective actions of cholinesterase inhibitors in Alzheimer disease
Nordberg A
ALZHEIMER DISEASE & ASSOCIATED DISORDERS 2006;20(2):S12-8

PET imaging of cortical C-11-nicotine binding correlates with the cognitive function of attention in Alzheimer's disease
Kadir A, Almkvist O, Wall A, Langstrom B, Nordberg A
PSYCHOPHARMACOLOGY 2006;188(4):509-20

Two-year follow-up of amyloid deposition in patients with Alzheimer's disease
Engler H, Forsberg A, Almkvist O, Blomquist G, Larsson E, Savitcheva I, et al
BRAIN 2006;:2856-66

A preclinical view of cholinesterase inhibitors in neuroprotection: do they provide more than symptomatic benefits in Alzheimer's disease?
Francis Pt, Nordberg A, Arnold Se
TRENDS IN PHARMACOLOGICAL SCIENCES 2005;26(2):104-11

Co-digestion of energy crops and the source-sorted organic fraction of municipal solid waste
Nordberg A, Edstrom M
WATER SCIENCE AND TECHNOLOGY 2005;52(1-2):217-22

Early changes in A beta levels in the brain of APPswe transgenic mice - Implication on synaptic density, alpha 7 neuronal nicotinic acetylcholine- and N-methyl-D-aspartate receptor levels
Unger C, Hedberg Mm, Mustafiz T, Svedberg Mm, Nordberg A
MOLECULAR AND CELLULAR NEUROSCIENCE 2005;30(2):218-27

Effect of memantine on the alpha 7 neuronal nicotinic receptors, synaptophysin- and low molecular weight MAP-2 levels in the brain of transgenic mice over-expressing human acetylcholinesterase
Unger C, Svedberg Mm, Schutte M, Bednar I, Nordberg A
JOURNAL OF NEURAL TRANSMISSION 2005;112(2):255-68

Expression of nicotinic receptors on primary cultures of rat astrocytes and up-regulation of the alpha 7, alpha 4 and beta 2 subunits in response to nanomolar concentrations of the beta-amyloid peptide(1-42)
Xiu J, Nordberg A, Zhang Jt, Guan Zz
NEUROCHEMISTRY INTERNATIONAL 2005;47(4):281-90

High selective expression of alpha 7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670/671 mutation: a possible association with neuritic plaques
Yu Wf, Guan Zz, Bogdanovic N, Nordberg A
EXPERIMENTAL NEUROLOGY 2005;192(1):215-25

Lovastatin stimulates up-regulation of alpha 7 nicotinic receptors in cultured neurons without cholesterol dependency, a mechanism involving production of the alpha-form of secreted amyloid precursor protein
Xiu J, Nordberg A, Shan Kr, Yu Wf, Olsson Jm, Nordman T, et al
JOURNAL OF NEUROSCIENCE RESEARCH 2005;82(4):531-41

Smoking during early pregnancy affects the expression pattern of both nicotinic and muscarinic acetylcholine receptors in human first trimester brainstem and cerebellum
Falk L, Nordberg A, Seiger A, Kjaeldgaard A, Hellstrom-lindahl E
NEUROSCIENCE 2005;132(2):389-97

Decreased nicotinic receptors in PC12 cells and rat brains influenced by fluoride toxicity - a mechanism relating to a damage at the level in post-transcription of the receptor genes
Shan Kr, Qi Xl, Long Yg, Nordberg A, Guan Zz
TOXICOLOGY 2004;200(2-3):169-77

Effect of subchronic galantamine treatment on neuronal nicotinic and muscarinic receptor subtypes in transgenic mice overexpressing human acetylcholinesterase
Svedberg Mm, Bednar I, Nordberg A
NEUROPHARMACOLOGY 2004;47(4):558-71

Functional studies of cholinergic activity in normal and Alzheimer disease states by imaging technique
Nordberg A
ACETYLCHOLINE IN THE CEREBRAL CORTEX 2004;:301-10

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
Klunk We, Engler H, Nordberg A, Wang Ym, Blomqvist G, Holt Dp, et al
ANNALS OF NEUROLOGY 2004;55(3):306-19

Long-lasting acetylcholinesterase splice variations in anticholinesterase-treated Alzheimer's disease patients
Darreh-shori T, Hellstrom-lindahl E, Flores-flores C, Guan Zz, Soreq H, Nordberg A
JOURNAL OF NEUROCHEMISTRY 2004;88(5):1102-13

Mild cognitive impairment - beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment
Winblad B, Palmer K, Kivipelto M, Jelic V, Fratiglioni L, Wahlund Lo, et al
JOURNAL OF INTERNAL MEDICINE 2004;256(3):240-6

Modulation of dopamine release by the nicotinic agonist epibatidine in the frontal cortex and the nucleus accumbens of naive and chronic nicotine treated rats
Bednar I, Friberg L, Nordberg A
NEUROCHEMISTRY INTERNATIONAL 2004;45(7):1049-55

Nicotine reduces A beta in the brain and cerebral vessels of APPsw mice
Hellstrom-lindahl E, Court J, Keverne J, Svedberg M, Lee M, Marutle A, et al
EUROPEAN JOURNAL OF NEUROSCIENCE 2004;19(10):2703-10

PET imaging of amyloid in Alzheimer's disease
Nordberg A
LANCET NEUROLOGY 2004;3(9):519-27

Preserved cognitive function after 12 months of treatment with rivastigmine in mild Alzheimer's disease in comparison with untreated AD and MCI patients
Almkvist O, Darreh-shori T, Stefanova E, Spiegel R, Nordberg A
EUROPEAN JOURNAL OF NEUROLOGY 2004;11(4):253-61

Reduced levels of A beta 40 and A beta 42 in brains of smoking controls and Alzheimer's patients
Hellstrom-lindahl E, Mousavi M, Ravid R, Nordberg A
NEUROBIOLOGY OF DISEASE 2004;15(2):351-60

Selective changes in expression of different nicotinic receptor subtypes in brain and adrenal glands of mice carrying human mutated gene for APP or over-expressing human acetylcholinestrase
Mousavi M, Bednar I, Nordberg A
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE 2004;22(7):545-9

A critical discussion of the role of neuroimaging in mild cognitive impairment
Wolf H, Jelic V, Gertz Hj, Nordberg A, Julin P, Wahlund Lo
ACTA NEUROLOGICA SCANDINAVICA 2003;:52-76

Cerebral glucose metabolism, cerebrospinal fluid-beta-amyloid(1-42) (CSF-A beta 42), tau and apolipoprotein E genotype in long-term rivastigmine and tacrine treated Alzheimer disease (AD) patients
Stefanova E, Blennow K, Almkvist O, Hellstrom-lindahl E, Nordberg A
NEUROSCIENCE LETTERS 2003;338(2):159-63

Correlation of oxidative stress and the loss of the nicotinic receptor alpha4 subunit in the temporal cortex of patients with Alzheimer's disease
Yu Wf, Nordberg A, Ravid R, Guan Zz
NEUROSCIENCE LETTERS 2003;338(1):13-6

Dual effects of nicotine on oxidative stress and neuroprotection in PC12 cells
Guan Zz, Yu Wf, Nordberg A
NEUROCHEMISTRY INTERNATIONAL 2003;43(3):243-9

Higher expression of alpha 7 nicotinic acetylcholine receptors in human fetal compared to adult brain
Falk L, Nordberg A, Seiger A, Kjaeldgaard A, Hellstrom-lindahl E
DEVELOPMENTAL BRAIN RESEARCH 2003;142(2):151-60

Imaging the pathology of Alzheimer's disease: amyloid-imaging with positron emission tomography
Klunk We, Engler H, Nordberg A, Bacskai Bj, Wang Ym, Price Jc, et al
NEUROIMAGING CLINICS OF NORTH AMERICA 2003;13(4):781-9

Loss of nicotinic receptors induced by beta-amyloid peptides in PC12 cells: Possible mechanism involving lipid peroxidation
Guan Zz, Yu Wf, Shan Kr, Nordman T, Olsson J, Nordberg A
JOURNAL OF NEUROSCIENCE RESEARCH 2003;71(3):397-406

Neuronal nicotinic and muscarinic receptor subtypes at different ages of transgenic mice overexpressing human acetylcholinesterase
Svedberg Mm, Svensson Al, Bednar I, Nordberg A
NEUROSCIENCE LETTERS 2003;340(2):148-52

Protein and mRNA levels of nicotinic receptors in brain of tobacco using controls and patients with Alzheimer's disease
Mousavi M, Hellstrom-lindahl E, Guan Zz, Shan Kr, Ravid R, Nordberg A
NEUROSCIENCE 2003;122(2):515-20

Selective decreases of nicotinic acetylcholine receptors in PC12 cells exposed to fluoride
Chen J, Shan Kr, Long Yg, Wang Yn, Nordberg A, Guan Zz
TOXICOLOGY 2003;183(1-3):235-42

Toward an early diagnosis and treatment of Alzheimer's disease
Nordberg A
INTERNATIONAL PSYCHOGERIATRICS 2003;15(3):223-37

Chronic fluoride toxicity decreases the number of nicotinic acetylcholine receptors in rat brain
Long Yg, Wang Yn, Chen J, Jiang Sf, Nordberg A, Guan Zz
NEUROTOXICOLOGY AND TERATOLOGY 2002;24(6):751-7

Chronic nicotine treatment reduces beta-amyloidosis in the brain of a mouse model of Alzheimer's disease (APPsw)
Nordberg A, Hellstrom-lindahl E, Lee M, Johnson M, Mousavi M, Hall R, et al
JOURNAL OF NEUROCHEMISTRY 2002;81(3):655-8

Chronic treatments with tacrine and (-)-nicotine induce different changes of nicotinic and muscarinic acetylcholine receptors in the brain of aged rat
Zhang X, Tian Jy, Svensson Al, Gong Zh, Meyerson B, Nordberg A
JOURNAL OF NEURAL TRANSMISSION 2002;109(3):377-92

Electroencephalography and glucose metabolism (positron-emission tomography) in dementing disorders
Jelic V, Konig T, Dierks T, Nordberg A, Wahlund Lo
METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY 2002;:21-

Elevated levels of A beta 1-40 and A beta 1-42 do not alter the binding sites of nicotinic receptor subtypes in the brain of APPswe and PS1 double transgenic mice
Marutle A, Unger C, Hellstrom-lindahl E, Wang J, Puolivali J, Tanila H, et al
NEUROSCIENCE LETTERS 2002;328(3):269-72

Interaction of a muscarinic cholinergic agonist on acetylcholine and dopamine receptors in the monkey brain studied with positron emission tomography
Hartvig P, Nordberg A, Torstenson R, Sjoberg P, Fasth Kj, Langstrom B
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 2002;13(4):199-204

Selective changes in the levels of nicotinic acetylcholine receptor protein and of corresponding mRNA species in the brains of patients with Parkinson's disease
Guan Zz, Nordberg A, Mousavi M, Rinne Jo, Hellstrom-lindahl E
BRAIN RESEARCH 2002;956(2):358-66

Selective nicotinic receptor consequences in APP(SWE) transgenic mice
Bednar I, Paterson D, Marutle A, Pham Tm, Svedberg M, Hellstrom-lindahl E, et al
MOLECULAR AND CELLULAR NEUROSCIENCE 2002;20(2):354-65

Smoking during pregnancy: A way to transfer the addiction to the next generation?
Hellstrom-lindahl E, Nordberg A
RESPIRATION 2002;69(4):289-93

Sustained cholinesterase inhibition in AD patients receiving rivastigmine for 12 months
Darreh-shori T, Almkvist O, Guan Zz, Garlind A, Strandberg B, Svensson Al, et al
NEUROLOGY 2002;59(4):563-72

The alpha 7 nicotinic receptors in human fetal brain and spinal cord
Falk L, Nordberg A, Seiger A, Kjaeldgaard A, Hellstrom-lindahl E
JOURNAL OF NEUROCHEMISTRY 2002;80(3):457-65

Upregulation of neuronal nicotinic receptor subunits alpha 4, beta 2, and alpha 7 in transgenic mice overexpressing human acetylcholinesterase
Svedberg Mm, Svensson Al, Johnson M, Lee M, Cohen O, Court J, et al
JOURNAL OF MOLECULAR NEUROSCIENCE 2002;18(3):211-22

Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice
Abbas N, Bednar I, Mix E, Marie S, Paterson D, Ljungberg A, et al
JOURNAL OF NEUROIMMUNOLOGY 2002;126(1-2):50-7

Expression of nicotinic acetylcholine receptors in human and rat adrenal medulla
Mousavi M, Hellstrom-lindahl E, Guan Zz, Bednar I, Nordberg A
LIFE SCIENCES 2001;70(5):577-90

Impaired cerebral glucose metabolism and cognitive functioning predict deterioration in mild cognitive impairment
Arnaiz E, Jelic V, Almkvist O, Wahlund Lo, Winblad B, Valind S, et al
NEUROREPORT 2001;12(4):851-5

Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia
Marutle A, Zhang X, Court J, Piggott M, Johnson M, Perry R, et al
JOURNAL OF CHEMICAL NEUROANATOMY 2001;22(1-2):115-26

Mechanisms of alcohol-nicotine interactions: Alcoholics versus smokers
Narahashi T, Soderpalm B, Ericson M, Olausson P, Engel Ja, Zhang X, et al
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 2001;25(5):152S-156S

Nicotine-induced alterations in the expression of nicotinic receptors in primary cultures from human prenatal brain
Hellstrom-lindahl E, Seiger A, Kjaeldgaard A, Nordberg A
NEUROSCIENCE 2001;105(3):527-34

Nicotinic receptor abnormalities of Alzheimer's disease: Therapeutic implications
Nordberg A
BIOLOGICAL PSYCHIATRY 2001;49(3):200-10

Reduced expression of neuronal nicotinic acetylcholine receptors during the early stages of damage by oxidative stress in PC12 cells
Guan Zz, Zhang X, Mousavi M, Tian Jy, Unger C, Nordberg A
JOURNAL OF NEUROSCIENCE RESEARCH 2001;66(4):551-8

Responder characteristics to a single oral dose of cholinesterase inhibitor: A double-blind placebo-controlled study with tacrine in Alzheimer patients
Almkvist O, Jelic V, Amberla K, Hellstrom-lindahl E, Meurling L, Nordberg A
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 2001;12(1):22-32

Suppressed expression of nicotinic acetylcholine receptors by nanomolar beta-amyloid peptides in PC12 cells
Guan Zz, Miao H, Tian Jy, Unger C, Nordberg A, Zhang X
JOURNAL OF NEURAL TRANSMISSION 2001;108(12):1417-33

Apolipoprotein E epsilon 4 allele has an impact on vascular reactivity in Alzheimer's disease
Algotsson A, Nordberg A, Winblad B
ARCHIVES OF GERONTOLOGY AND GERIATRICS 2000;31(3):221-231

Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease
Guan Zz, Zhang X, Ravid R, Nordberg A
JOURNAL OF NEUROCHEMISTRY 2000;74(1):237-43

Development of ligands for in vivo imaging of cerebral nicotinic receptors
Sihver W, Nordberg A, Langstrom B, Mukhin Ag, Koren Ao, Kimes As, et al
BEHAVIOURAL BRAIN RESEARCH 2000;113(1-2):143-57

Early diagnosis of Alzheimer disease with positron emission tomography
Jelic V, Nordberg A
ALZHEIMER DISEASE & ASSOCIATED DISORDERS 2000;:S109-13

Influence of lipid peroxidation on the nicotinic acetylcholine receptors in PC12 cells
Guan Zz, Zhang X, Nordberg A
NEUROSCIENCE LETTERS 2000;286(3):163-6

Ligands for in vivo imaging of nicotinic receptor subtypes in Alzheimer brain
Sihver W, Langstrom B, Nordberg A
ACTA NEUROLOGICA SCANDINAVICA 2000;:27-33

Monitoring of a biogas process using electronic gas sensors and near-infrared spectroscopy (NIR)
Nordberg A, Hansson M, Sundh I, Nordkvist E, Carlsson H, Mathisen B
WATER SCIENCE AND TECHNOLOGY 2000;41(3):1-8

Neuronal nicotinic receptors in the human brain
Paterson D, Nordberg A
PROGRESS IN NEUROBIOLOGY 2000;61(1):75-111

Neuroprotection in Alzheimer's disease - new strategies for treatment
Nordberg A
Neurotoxicity research 2000;2(2-3):157-65

Quantitative electroencephalography in mild cognitive impairment: longitudinal changes and possible prediction of Alzheimer's disease
Jelic V, Johansson Se, Almkvist O, Shigeta M, Julin P, Nordberg A, et al
NEUROBIOLOGY OF AGING 2000;21(4):533-40

Rats exhibiting acute behavioural tolerance to nicotine have more [I-125]alpha-bungarotoxin binding sites in brain than rats not exhibiting tolerance
Zhang X, Paterson D, James R, Gong Zh, Liu C, Rosecrans J, et al
BEHAVIOURAL BRAIN RESEARCH 2000;113(1-2):105-15

Spatial pattern of cerebral glucose metabolism (PET) correlates with localization of intracerebral EEG-generators in Alzheimer's disease
Dierks T, Jelic V, Pascual-marqui Rd, Wahlund Lo, Julin P, Linden Dej, et al
CLINICAL NEUROPHYSIOLOGY 2000;111(10):1817-24

Activity of acetylcholinesterase in CSF increases in Alzheimer's patients after treatment with tacrine
Nordberg A, Hellstrom-lindahl E, Almkvist O, Meurling L
ALZHEIMERS REPORTS 1999;2(6):347-352

A follow-up study of the family with the Swedish APP 670/671 Alzheimer's disease mutation
Wahlund Lo, Basun H, Almkvist O, Julin P, Axelman K, Shigeta M, et al
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 1999;10(6):526-33

Autoradiographic comparison of [H-3](-)nicotine, [H-3]cytisine and [H-3]epibatidine binding in relation to vesicular acetylcholine transport sites in the temporal cortex in Alzheimer's disease
Sihver W, Gillberg Pg, Svensson Al, Nordberg A
NEUROSCIENCE 1999;94(3):685-96

beta-Estradiol attenuate amyloid beta-peptide toxicity via nicotinic receptors
Svensson Al, Nordberg A
NEUROREPORT 1999;10(17):3485-9

Brain regions associated with episodic retrieval in normal aging and Alzheimer's disease
Backman L, Andersson Jlr, Nyberg L, Winblad B, Nordberg A, Almkvist O
NEUROLOGY 1999;52(9):1861-70

Decreased protein level of nicotinic receptor alpha 7 subunit in the frontal cortex from schizophrenic brain
Guan Zz, Zhang X, Blennow K, Nordberg A
NEUROREPORT 1999;10(8):1779-82

Diagnostic accuracies of quantitative EEG and PET in mild Alzheimer's disease
Jelic V, Wahlund Lo, Almkvist O, Johansson Se, Shigeta M, Winblad B, et al
ALZHEIMERS REPORTS 1999;2(5):291-298

Impairment of neocortical metabolism predicts progression in Alzheimer's disease
Herholz K, Nordberg A, Salmon E, Perani D, Kessler J, Mielke R, et al
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 1999;10(6):494-504

In vivo positron emission tomography studies on the novel nicotinic receptor agonist [C-11]MPA compared with [C-11]ABT-418 and (S)(-)[C-11]nicotine in rhesus monkey
Sihver W, Fasth Kj, Ogren M, Lundqvist H, Bergstrom M, Watanabe Y, et al
NUCLEAR MEDICINE AND BIOLOGY 1999;26(6):633-40

Neuronal nicotinic receptor deficits in Alzheimer patients with the Swedish amyloid precursor protein 670/671 mutation
Marutle A, Warpman U, Bogdanovic N, Lannfelt L, Nordberg A
JOURNAL OF NEUROCHEMISTRY 1999;72(3):1161-9

PET studies and cholinergic therapy in Alzheimer's disease
Nordberg A
REVUE NEUROLOGIQUE 1999;:4S53-4S63

PET studies and cholinergic therapy in Alzheimer's disease
Nordberg A
Revue neurologique 1999;155 Suppl 4():S53-63

Regional distribution of nicotinic receptor subunit mRNAs in human brain: comparison between Alzheimer and normal brain
Hellstrom-lindahl E, Mousavi M, Zhang X, Ravid R, Nordberg A
MOLECULAR BRAIN RESEARCH 1999;66(1-2):94-103

Synthesis and characterization of binding of 5-[76Br]bromo-3-[[2(S)-azetidinyl]methoxy]pyridine, a novel nicotinic acetylcholine receptor ligand, in rat brain
Sihver W, Fasth Kj, Horti Ag, Koren Ao, Bergström M, Lu L, et al
Journal of neurochemistry 1999;73(3):1264-72

Synthesis and characterization of binding of 5-[Br-76]bromo-3-[[2(S)-azetidinyl]methoxy]pyridine, a novel nicotinic acetylcholine receptor ligand, in rat brain
Sihver T, Fasth Kj, Horti Ag, Koren Ao, Bergstrom M, Lu L, et al
JOURNAL OF NEUROCHEMISTRY 1999;73(3):1264-1272

Cholinesterase inhibitors in the treatment of Alzheimer's disease - A comparison of tolerability and pharmacology
Nordberg A, Svensson Al
DRUG SAFETY 1998;19(6):465-80

Chronic ethanol treatment decreases [H-3]epibatidine and [H-3]nicotine binding and differentially regulates mRNA levels of nicotinic acetylcholine receptor subunits expressed in M10 and SH-SY5Y neuroblastoma cells
Gorbounova O, Svensson Al, Jonsson P, Mousavi M, Miao H, Hellstrom-lindahl E, et al
JOURNAL OF NEUROCHEMISTRY 1998;70(3):1134-42

Differential changes of nicotinic receptors in the rat brain following ibotenic acid and 192-IgG saporin lesions of the nucleus basalis magnocellularis
Bednar I, Zhang X, Dastranj-sedghi R, Nordberg A
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE 1998;16(7-8):661-8

Interaction of the nicotinic agonist (R,S)-3-pyridyl-1-methyl-2-(3-pyridyl)-azetidine (MPA) with nicotinic acetylcholine receptor subtypes expressed in cell lines and rat cortex
Zhang X, Gong Zh, Fasth Kj, Langstrom B, Nordberg A
NEUROCHEMISTRY INTERNATIONAL 1998;32(5-6):435-41

Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease
Jonhagen Me, Nordberg A, Amberla K, Backman L, Ebendal T, Meyerson B, et al
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 1998;9(5):246-57

In vitro evaluation of C-11-labeled (S)-nicotine, (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole, and (R,S)-1-methyl-2-(3-pyridyl)azetidine as nicotinic receptor ligands for positron emission tomography studies
Sihver W, Fasth Kj, Ogren M, Bivehed H, Bergstrom M, Nordberg A, et al
JOURNAL OF NEUROCHEMISTRY 1998;71(4):1750-60

Laminar distribution of nicotinic receptor subtypes in human cerebral cortex as determined by [H-3](-)nicotine, [H-3]cytisine and [H-3]epibatidine in vitro autoradiography
Sihver W, Gillberg Pg, Nordberg A
NEUROSCIENCE 1998;85(4):1121-33

Longitudinal changes in quantitative EEG during long-term tacrine treatment of patients with Alzheimer's disease
Jelic V, Dierks T, Amberla K, Almkvist O, Winblad B, Nordberg A
NEUROSCIENCE LETTERS 1998;254(2):85-8

Long-term tacrine treatment in three mild Alzheimer patients: Effects on nicotinic receptors, cerebral blood flow, glucose metabolism, EEG, and cognitive abilities
Nordberg A, Amberla K, Shigeta M, Lundqvist H, Viitanen M, Hellstrom-lindahl E, et al
ALZHEIMER DISEASE & ASSOCIATED DISORDERS 1998;12(3):228-37

Nicotine exposure during a critical period of development leads to persistent changes in nicotinic acetylcholine receptors of adult rat brain
Miao H, Liu C, Bishop K, Gong Zh, Nordberg A, Zhang X
JOURNAL OF NEUROCHEMISTRY 1998;70(2):752-62

Postnatal changes of nicotinic acetylcholine receptor alpha 2, alpha 3, alpha 4, alpha 7 and beta 2 subunits genes expression in rat brain
Zhang X, Liu Ch, Miao H, Gong Zh, Nordberg A
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE 1998;16(6):507-18

Regional distribution of nicotinic receptors during prenatal development of human brain and spinal cord
Hellstrom-lindahl E, Gorbounova O, Seiger A, Mousavi M, Nordberg A
DEVELOPMENTAL BRAIN RESEARCH 1998;108(1-2):147-60

Regional distribution of subtypes of nicotinic receptors in human brain and effect of aging studied by (+/-)-[H-3]epibatidine
Marutle A, Warpman U, Bogdanovic N, Nordberg A
BRAIN RESEARCH 1998;801(1-2):143-9

Regulation of nicotinic receptors in the brain of mice withdrawn from chronic oral nicotine treatment
Pietila K, Lahde T, Attila M, Ahtee L, Nordberg A
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 1998;357(2):176-82

Regulation of nicotinic receptor subtypes following chronic nicotinic agonist exposure in M10 and SH-SY5Y neuroblastoma cells
Warpman U, Friberg L, Gillespie A, Hellstrom-lindahl E, Zhang X, Nordberg A
JOURNAL OF NEUROCHEMISTRY 1998;70(5):2028-37

(S-)-[C-11]nicotine binding assessed by PET: A dual tracer model evaluated in the rhesus monkey brain
Lundqvist H, Nordberg A, Hartvig P, Langstrom S
ALZHEIMER DISEASE & ASSOCIATED DISORDERS 1998;12(3):238-46

Tacrine and donepezil attenuate the neurotoxic effect of A beta(25-35) in rat PC12 cells
Svensson Al, Nordberg A
NEUROREPORT 1998;9(7):1519-22

Apolipoprotein E epsilon 4 allele decreases functional connectivity in Alzheimer's disease as measured by EEG coherence
Jelic V, Julin P, Shigeta M, Nordberg A, Lannfelt L, Winblad B, et al
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 1997;63(1):59-65

Brain activation in young and older adults during implicit and explicit retrieval
Backman L, Almkvist O, Andersson J, Nordberg A, Winblad B, Reineck R, et al
JOURNAL OF COGNITIVE NEUROSCIENCE 1997;9(3):378-91

Imaging of nicotinic and muscarinic receptors in Alzheimer's disease: Effect of tacrine treatment
Nordberg A, Lundqvist H, Hartvig P, Andersson J, Johansson M, Hellstromlindahl E, et al
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 1997;8(2):78-84

Nicotinic receptors, muscarinic receptors and choline acetyltransferase activity in the temporal cortex of Alzheimer patients with differing apolipoprotein E genotypes
Svensson Al, Warpman U, Hellstromlindahl E, Bogdanovic N, Lannfelt L, Nordberg A
NEUROSCIENCE LETTERS 1997;232(1):37-40

No difference in cerebral glucose metabolism in patients with Alzheimer disease and differing apolipoprotein E genotypes
Corder Eh, Jelic V, Basun H, Lannfelt L, Valind S, Winblad B, et al
ARCHIVES OF NEUROLOGY 1997;54(3):273-7

Regional brain distribution and binding of the muscarinic receptor agonist CI-979 studied by positron emission tomography in the monkey
Hartvig P, Torstenson R, Bjurling P, Fasth Kj, Langstrom B, Nordberg A
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 1997;8(5):259-66

Treatment of Alzheimer disease with tacrine: A cost-analysis model
Wimo A, Karlsson G, Nordberg A, Winblad B
ALZHEIMER DISEASE & ASSOCIATED DISORDERS 1997;11(4):191-200

Apolipoprotein E epsilon 4 allele, skin vessel reactivity and vascular risk factors in Alzheimer's disease
Algotsson A, Nordberg A, Lannfelt L, Almkvist O, Winblad B
ARCHIVES OF GERONTOLOGY AND GERIATRICS 1996;22(3):223-32

Application of PET in dementia disorders
Nordberg A
ACTA NEUROLOGICA SCANDINAVICA 1996;:71-6

Biphasic effect of tacrine on acetylcholine release in rat brain via M(1) and M(2) receptors
Svensson Al, Zhang X, Nordberg A
BRAIN RESEARCH 1996;726(1-2):207-12

Differential co-expression of nicotinic acetylcholine receptor alpha 4 and beta 2 subunit genes in various regions of rat brain
Liu C, Nordberg A, Zhang X
NEUROREPORT 1996;7(10):1645-9

Effect of tacrine on in vivo release of dopamine and its metabolites in the striatum of freely moving rats
Warpman U, Zhang X, Nordberg A
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 1996;277(2):917-22

Functional studies of new drugs for the treatment of Alzheimer's disease
Nordberg A
ACTA NEUROLOGICA SCANDINAVICA 1996;:137-44

Muscarinic receptor subtypes in subpopulations of human blood mononuclear cells as analyzed by RT-PCR technique
Hellstromlindahl E, Nordberg A
JOURNAL OF NEUROIMMUNOLOGY 1996;68(1-2):139-44

Pharmacological treatment of cognitive dysfunction in dementia disorders
Nordberg A
ACTA NEUROLOGICA SCANDINAVICA 1996;:87-92

Steady-state pharmacokinetics of tacrine in long-term treatment of Alzheimer patients
Johansson M, Hellstromlindahl E, Nordberg A
DEMENTIA 1996;7(2):111-7

Tacrine interacts with an allosteric activator site on alpha 4 beta 2 nAChRs in M10 cells
Svensson Al, Nordberg A
NEUROREPORT 1996;7(13):2201-5

Epibatidine and ABT 418 reveal selective losses of alpha 4 beta 2 nicotinic receptors in Alzheimer brains
Warpman U, Nordberg A
NEUROREPORT 1995;6(17):2419-23

GENETIC AND ENVIRONMENTAL ASPECTS OF THE ROLE OF NICOTINIC RECEPTORS IN NEURODEGENERATIVE DISORDERS - EMPHASIS ON ALZHEIMERS-DISEASE AND PARKINSONS-DISEASE
James Jr, Nordberg A
BEHAVIOR GENETICS 1995;25(2):149-59

INFLUENCE OF AGE AND GENDER ON SKIN VESSEL REACTIVITY TO ENDOTHELIUM-DEPENDENT AND ENDOTHELIUM-INDEPENDENT VASODILATORS TESTED WITH IONTOPHORESIS AND A LASER-DOPPLER PERFUSION IMAGER
Algotsson A, Nordberg A, Winblad B
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 1995;50(2):M121-7

KINETIC-ANALYSIS OF REGIONAL (S)(-)C-11-NICOTINE BINDING IN NORMAL AND ALZHEIMER BRAINS - IN-VIVO ASSESSMENT USING POSITRON EMISSION TOMOGRAPHY
Nordberg A, Lundqvist H, Hartvig P, Lilja A, Langstrom B
ALZHEIMER DISEASE & ASSOCIATED DISORDERS 1995;9(1):21-7

REGIONAL DEPOSITION OF INHALED C-11 NICOTINE VAPOR IN THE HUMAN AIRWAY AS VISUALIZED BY POSITRON EMISSION TOMOGRAPHY
Bergstrom M, Nordberg A, Lunell E, Antoni G, Langstrom B
CLINICAL PHARMACOLOGY & THERAPEUTICS 1995;57(3):309-17

REGULATION OF ALPHA-4-BETA-2 NICOTINIC ACETYLCHOLINE-RECEPTORS IN M10 CELLS FOLLOWING TREATMENT WITH NICOTINIC AGENTS
Zhang X, Gong Zh, Helstromlindahl E, Nordberg A
NEUROREPORT 1995;6(2):313-7

SKIN VESSEL REACTIVITY IS IMPAIRED IN ALZHEIMERS-DISEASE
Algotsson A, Nordberg A, Almkvist O, Winblad B
NEUROBIOLOGY OF AGING 1995;16(4):577-82

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