Histiocytoses and Hematology

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The major aim of our studies is to improve survival and reduce long-term sequele in children affected by cancer and blood disorders, with focus on hematological disorders and histiocytoses (hemophagocytic lymphohistiocytosis, HLH, and Langerhans cell histiocytosis, LCH). We aim to develop better treatment regimens, and better diagnostic and monitoring tools.

With the ultimate target to improve treatment and outcome, we also investigate underlying genetics, immunology and biology of the disorders. In addition, we also study psychosocial factors affecting children with cancer and their parents. Our studies range from molecular biology, through cellular studies to clinical studies and psychosocial investigations. They comprise the following main areas which are presented in detail.

Research areas

  • Hemophagocytic Lymphohistiocytosis (HLH) Clinical Studies
  • Hemophagocytic Lymphohistiocytosis (HLH) Biological Studies
  • Langerhans Cell Histiocytosis (LCH)
  • Hematological disorders [Kostmann's disease (SCN), and ITP]

The research projects are presented more in detail here

Members of the research group

Research leader:

Professor/överläkare

Jan-Inge Henter

Telefon: 08-517 725 36
Enhet: Institutionen för kvinnors och barns hälsa (KBH), K6
E-post: Jan-Inge.Henter@ki.se

PhDs

Göran Carlsson, MD PhD Senior consultant
Désirée Gavhed, PhD Project coordinator
AnnaCarin Horne, MD PhD Fellow in paediatrics
Elisabet Berglöf, PhD Research assistant
Miriam Entesarian, PhD Postdoc
Magdalini Lourda, Postdoc

PhD students

Helena Trottestam, MD Fellow in paediatrics
Marie Meeths, MD Intern
Selma Olsson Åkefelt, MD Fellow in paediatrics
Maja Ideström, MD Consultant
Li Jalmsell, MD Fellow
Kajsa Palmqvist, MD Fellow

Collaborating researchers

Chengyun Zheng, MD PhD Researcher
Evaldas Laurencikas, MD PhD Neuroradiologist
Ingrid Van't Hooft, Psychologist PhD Neuropsychologist
Ulrika Kreicbergs, RN PhD, Docent Researcher

Other staff

Edvard Nordenskjöld Student
Egle Kvedaraite Student Läk.programmet
Alexandra Löfstedt Student Läk.programmet
Tatiana Greenwood, MD Research assistant

Pediatrics