Histiocytoses and Hematology

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The major aim of our studies is to improve survival and reduce long-term sequelae in children affected by cancer and blood disorders, with focus on hematological disorders and histiocytoses (hemophagocytic lymphohistiocytosis, HLH, and Langerhans cell histiocytosis, LCH).

We aim to develop better treatment regimens, and better diagnostic and monitoring tools. By this, the survival for patients severely affected by these disorders has increased significantly.

In addition, we perform psychosocial research aiming to improve the treatment and care of pediatric cancer patients and their families.

Research group leader:

Head of unit

Jan-Inge Henter

Phone: 08-517 725 36
Organizational unit: Division of Pediatric Oncology
E-mail: Jan-Inge.Henter@ki.se

With the ultimate target to improve treatment and outcome, we also investigate underlying genetics, immunology and biology of the disorders. In addition, we also study psychosocial factors affecting children with cancer and their parents. Our studies range from molecular biology, through cellular studies to clinical studies and psychosocial investigations. They comprise the following main areas which are presented in detail.

Research areas

  • Hemophagocytic Lymphohistiocytosis (HLH) Clinical studies
  • Hemophagocytic Lymphohistiocytosis (HLH) Biological studies
  • Langerhans Cell Histiocytosis (LCH) Clinical and Biological studies

The research projects are presented more in detail here

Members of the research group

Désirée Gavhed, PhD, Project coordinator
Elisabet Bergsten, PhD, Research coordinator
Magdalini Lourda, Assistant professor
Nikolas Herold, MD, Dr. med, postdoc
AnnaCarin Horne, MD, PhD, postdoc, paediatrician
Selma Olsson Åkefeldt, MD, PhD, paediatrician
Marie Meeths, MD, PhD, Fellow in apediatrics
Maja Ideström, MD, PhD, Consultant

PhD students

Bianca Tesi, MD
Tatiana Greenwood, MD, Paediatrician
Alexandra Löfstedt, MD, Intern
Egle Kvedaraite, Medical student

Collaborating researchers

Yenan Bryceson, PhD, Associate professor
Mattias Svensson, PhD, Associate professor
Chengyun Zheng, MD, PhD, Researcher
Evaldas Laurencikas, MD, PhD Neuroradiologist
Ingrid Van't Hooft, Psychologist, PhD, Neuropsychologist
Ulrika Kreicbergs, RN, PhD, Professor
Li Jalmsell, MD, Fellow in oncology

Other staff

Ida Hed Myrberg, Statistician
Viktoria Lundbring, Student