Department of Oncology-Pathology

The Swedish Society of Medicine’s 2025 award for best scientific project proposal has been granted to Alexios Matikas at the Department of Oncology-Pathology. His research project, “Integrated multi-omics for prediction of response to antibody-drug conjugates”, aims to improve the ability to predict which breast cancer patients are likely to benefit from a specific treatment using antibody-drug conjugates.

Alexios Matikas and Theodoros Foukakis have published a secondary analysis of the phase 3 PANTHER study in Lancet Regional Health Europe, showing that all patients with operated, lymph node-positive breast cancer benefit from more frequent chemotherapy every two weeks compared to the standard treatment every three weeks.

Thuy Tran’s research group has been awarded 8 million SEK over three years from the Erling-Persson Foundation to develop a precision-focused, theranostic method that integrates both diagnostics and treatment of advanced solid tumors. Thuy Tran’s research focuses on creating an innovative, targeted platform that aims to provide less invasive, personalized, and targeted treatment options. The goal is to improve both patient well-being and treatment outcomes.

In a study published in Biomarkers Research, Kenny Rodriguez-Wallberg, Xia Hao, and Jian Zhao investigate how mitochondria change from being evenly distributed to forming clusters during the maturation of mouse egg cells, providing a new method for evaluating egg cell health.