Pernilla Nikamo

Publications
CV
Public outreach and news

Articles

Article: EMBO MOLECULAR MEDICINE. 2024;16(3):596-615

Rare coding variants in NOX4 link high ROS levels to psoriatic arthritis mutilans.

Wang S; Nikamo P; Laasonen L; Gudbjornsson B; Ejstrup L; Iversen L; Lindqvist U; Alm JJ; Eisfeldt J; Zheng X; Catrina S-B; Taylan F; Vaz R; Ståhle M; Tapia-Paez I
Journal article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2023;143(5):s140

813 Rare coding variants in NOX4 link high superoxide levels to psoriatic arthritis mutilans

Wang S; Nikamo P; Laasonen L; Gudbjornsson B; Eistrup L; Iversen L; Lindqvist U; Alm J; Eisfeldt J; Zheng X; Catrina S; Taylan F; Vaz R; Stahle M; Paez IT
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2021;39(4):775-780

HLA-B*27 is significantly enriched in Nordic patients with psoriatic arthritis mutilans.

Nikamo P; Gudbjornsson B; Laasonen L; Ejstrup L; Iversen L; Lindqvist U; Padyukov L; Ståhle M
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;147(5):1742-1752

Chromatin interactions in differentiating keratinocytes reveal novel atopic dermatitis- and psoriasis-associated genes.

Sahlén P; Spalinskas R; Asad S; Mahapatra KD; Höjer P; Anil A; Eisfeldt J; Srivastava A; Nikamo P; Mukherjee A; Kim K-H; Bergman O; Ståhle M; Sonkoly E; Pivarcsi A; Wahlgren C-F; Nordenskjöld M; Taylan F; Bradley M; Tapia-Páez I
Article: JAMA DERMATOLOGY. 2021;157(6):1-8

Long-term Outcomes and Prognosis in New-Onset Psoriasis.

Svedbom A; Mallbris L; Larsson P; Nikamo P; Wolk K; Kjellman P; Sonkoly E; Eidsmo L; Lindqvist U; Ståhle M
Article: ARCHIVES OF DERMATOLOGICAL RESEARCH. 2019;311(6):435-442

The prevalence of ADH1B and OPRM1 alleles predisposing for alcohol consumption are increased in the Hungarian psoriasis population.

Szentkereszty-Kovács Z; Fiatal S; Szegedi A; Kovács D; Janka E; Herszényi K; Holló P; Nikamo P; Ståhle M; Remenyik É; Törőcsik D
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(2):550-561

MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis.

Srivastava A; Nikamo P; Lohcharoenkal W; Li D; Meisgen F; Xu Landén N; Ståhle M; Pivarcsi A; Sonkoly E
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015;135(8):1969-1976

Association with Genetic Variants in the IL-23 and NF-κB Pathways Discriminates between Mild and Severe Psoriasis Skin Disease.

Nikamo P; Lysell J; Ståhle M
Article: ACTA DERMATO-VENEREOLOGICA. 2015;95(4):457-461

Clinical characterisation at onset of childhood psoriasis - a cross sectional study in Sweden.

Lysell J; Tessma M; Nikamo P; Wahlgren C-F; Ståhle M
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(6):1535-1541

Genetic variants of the IL22 promoter associate to onset of psoriasis before puberty and increased IL-22 production in T cells.

Nikamo P; Cheuk S; Lysell J; Enerbäck C; Bergh K; Xu Landén N; Eidsmo L; Ståhle M
Article: MOLECULAR PSYCHIATRY. 2014;19(3):334-341

The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression.

Lavebratt C; Olsson S; Backlund L; Frisén L; Sellgren C; Priebe L; Nikamo P; Träskman-Bendz L; Cichon S; Vawter MP; Osby U; Engberg G; Landén M; Erhardt S; Schalling M
Article: PLOS ONE. 2014;9(9):e104382

Accelerating translational research by clinically driven development of an informatics platform--a case study.

Abugessaisa I; Saevarsdottir S; Tsipras G; Lindblad S; Sandin C; Nikamo P; Ståhle M; Malmström V; Klareskog L; Tegnér J
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2013;133(2):411-417

Genetic association with ERAP1 in psoriasis is confined to disease onset after puberty and not dependent on HLA-C*06.

Lysell J; Padyukov L; Kockum I; Nikamo P; Ståhle M
Article: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2013;27(1):e124-e127

Lack of association between filaggrin gene mutations and onset of psoriasis in childhood.

Winge MCG; Suneson J; Lysell J; Nikamo P; Liedén A; Nordenskjöld M; Wahlgren CF; Bradley M; Ståhle M
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2012;22(9):632-640

Polymorphisms in AKR1C4 and HSD3B2 and differences in serum DHEAS and progesterone are associated with paranoid ideation during mania or hypomania in bipolar disorder.

Johansson AGM; Nikamo P; Schalling M; Landén M
Article: EXPERIMENTAL DERMATOLOGY. 2012;21(3):221-223

Cost-effective HLA-Cw06:02 typing in a Caucasian population.

Nikamo P; Ståhle M
Article: PLOS ONE. 2012;7(5):e35439

HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13.

Asad S; Nikamo P; Gyllenberg A; Bennet H; Hansson O; Wierup N; Diabetes Incidence in Sweden Study Group; Carlsson A; Forsander G; Ivarsson S-A; Larsson H; Lernmark Å; Lindblad B; Ludvigsson J; Marcus C; Rønningen KS; Nerup J; Pociot F; Luthman H; Fex M; Kockum I
Article: PLOS ONE. 2012;7(8):e43057

P2RX7: expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1.

Backlund L; Lavebratt C; Frisén L; Nikamo P; Hukic Sudic D; Träskman-Bendz L; Landén M; Edman G; Vawter MP; Ösby U; Schalling M
Journal article: EUROPEAN PSYCHIATRY. 2012;27:1

P-163 - P2RX7: Expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1

Backlund L; Lavebratt C; Frisen L; Nikamo P; Vawter MP; Sudic DH; Träskman-Bendz L; Landén M; Edman G; Schalling M
Article: JOURNAL OF AFFECTIVE DISORDERS. 2011;133(1-2):346-351

AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder.

Johansson AGM; Nikamo P; Schalling M; Landén M
Article: BIPOLAR DISORDERS. 2011;13(5-6):500-508

Cognitive manic symptoms associated with the P2RX7 gene in bipolar disorder.

Backlund L; Nikamo P; Hukic DS; Ek IR; Träskman-Bendz L; Landén M; Edman G; Schalling M; Frisén L; Osby U
Article: PLOS ONE. 2010;5(9):e12632

CRY2 is associated with rapid cycling in bipolar disorder patients.

Sjöholm LK; Backlund L; Cheteh EH; Ek IR; Frisén L; Schalling M; Osby U; Lavebratt C; Nikamo P
Article: PSYCHOLOGICAL SCIENCE. 2009;20(2):198-206

Genetic gating of human fear learning and extinction: possible implications for gene-environment interaction in anxiety disorder.

Lonsdorf TB; Weike AI; Nikamo P; Schalling M; Hamm AO; Ohman A
Article: DIABETIC MEDICINE. 2007;24(12):1473-1477

No evidence of association of the PDCD1 gene with Type 1 diabetes.

Asad S; Nikamo P; Törn C; Landin-Olsson M; Lernmark A; Alarcón-Riquelme M; Kockum I; Diabetes Incidence in Sweden Study Group
Article: DIABETES. 2004;53(6):1584-1591

Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families.

Holm P; Rydlander B; Luthman H; Kockum I; European Consortium for IDDM Genome Studies
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2004;74(4):647-660

Novel analytical methods applied to type 1 diabetes genome-scan data.

Pociot F; Karlsen AE; Pedersen CB; Aalund M; Nerup J; European Consortium for IDDM Genome Studies
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2001;69(6):1301-1313

A genomewide scan for type 1-diabetes susceptibility in Scandinavian families: identification of new loci with evidence of interactions.

Nerup J; Pociot F; European Consortium for IDDM Studies
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All other publications

Preprint: BIORXIV. 2023

Rare coding variants in NOX4 link high superoxide levels to psoriatic arthritis mutilans

Wang S; Nikamo P; Laasonen L; Gudbjornsson B; Ejstrup L; Iversen L; Lindqvist U; Alm JJ; Eisfeldt J; Zheng X; Catrina S-B; Taylan F; Vaz R; Ståhle M; Tapia-Paez I
Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2023;31:389

Genetic and functional studies of novel candidate genes for Psoriatic Arthritis Mutilans

Wang S; Nikamo P; Vaz R; Taylan F; Eisfeldt J; Zheng X; Laasonen L; Tapia-Paez I
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2023;143(5):S140

Rare coding variants in NOX4 link high superoxide levels to psoriatic arthritis mutilans

Wang S; Nikamo P; Laasonen L; Gudbjornsson B; Eistrup L; Iversen L; Lindqvist U; Alm J; Eisfeldt J; Zheng X; Catrina S; Taylan F; Vaz R; Stahle M; Paez IT
Corrigendum: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;152(1):307

Chromatin interactions in differentiating keratinocytes reveal novel atopic dermatitis- and psoriasis-associated genes (vol 147, pg 1742, 2021)

Sahlen P; Spalinskas R; Asad S; Mahapatra KD; Hojer P; Anil A; Eisfeldt J; Srivastava A; Nikamo P; Mukherjee A; Kim K-H; Bergman O; Stahle M; Sonkoly E; Pivarcsi A; Wahlgren C-F; Nordenskjold M; Taylan F; Tapia-Paez I; Bradley M
Letter: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2020;140(8):1653-1656.e1

Interaction between Smoking and HLA-C*06:02 on the Response to Ustekinumab in Psoriasis.

Svedbom A; Nikamo P; Ståhle M
Editorial comment: ACTA DERMATO-VENEREOLOGICA. 2017;97(8):952-954

Transient Elastography May Improve Detection of Liver Fibrosis in Psoriasis Patients Treated with Methotrexate.

Talme T; Nikamo P; Rosenberg P; Ståhle M
Letter: EXPERIMENTAL DERMATOLOGY. 2017;26(5):444-446

IL-22 binding protein regulates murine skin inflammation.

Lindahl H; Martini E; Brauner S; Nikamo P; Gallais Serezal I; Guerreiro-Cacais AO; Jagodic M; Eidsmo L; Ståhle M; Olsson T
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2016;136(9):S226

MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis

Srivastava A; Nikamo P; Lohcharoenkal W; Li D; Meisgen F; Landen N; Stahle MM; Pivarcsi A; Sonkoly E
Conference publication: EXPERIMENTAL DERMATOLOGY. 2016;25:14

MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis

Srivastava A; Nikamo P; Lohcharoenkal W; Li D; Meisgen F; Landen NX; Stahle M; Pivarcsi A; Sonkoly E
Conference publication: BRITISH JOURNAL OF DERMATOLOGY. 2014;171(6):E153

It is time to redefine psoriasis type I as three different types of psoriasis

Nikamo P; Stahle M
Letter: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2013;133(3):836-839

Association of cardiovascular and metabolic disease genes with psoriasis.

Lu Y; Chen H; Nikamo P; Qi Low H; Helms C; Seielstad M; Liu J; Bowcock AM; Stahle M; Liao W
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2013;133:S140

Psoriasis; severe compared to mild

Nikamo P; Stahle M
Conference publication: EUROPEAN PSYCHIATRY. 2012;27

P2RX7: EXPRESSION RESPONDS TO SLEEP DEPRIVATION AND ASSOCIATES WITH RAPID CYCLING IN BIPOLAR DISORDER TYPE 1

Backlund L; Lavebratt C; Frisen L; Nikamo P; Vawter MP; Sudic DH; Traskman-Bendz L; Landen M; Edman G; Schalling M
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2012;132:S56

Clinical characterization at onset of childhood psoriasis in Sweden - a population based study

Lysell J; Nikamo P; Wahlgren C; Stahle M
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2011;131:S70

Pathway analysis: The new way from GWAS to disease genes

Nikamo P; Stahle M
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2010;20:S403

Cys145Ser change in the AKR1C4 gene associated with manic irritability and lower progesterone in male bipolar patients

Johansson AGM; Nikamo P; Landen M
Meeting abstract: EUROPEAN PSYCHIATRY. 2008;23:S225

Association between G72/30 haplotypes and bipolar disorder in a Swedish sample

Backlund L; Nikamo P; Rosvall L; Frisen L; Landen M; Ladanayi J; Traeskman-Bendz L; Agren H; Schalling M; Oesby U
Corrigendum: DIABETIC MEDICINE. 2008;25(2):243

No evidence of association of the PDCD1 gene with Type 1 diabetes (vol 24, pg 1473, 2007)

Fawwaz S; Nikamo P; Toern C; Landin-Olsson M; Lernmark A; Alarcon-Riquelme M; Kockum I
Conference publication: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2008;11:71

Human fear learning and extinction are modulated by different genetic polymorphisms

Schalling M; Lonsdorf TB; Weike AI; Nikamo P; Hamm AO; Ohman A
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2003;1005:352-355

No evidence for linkage in Swedish multiplex T1DM families to IL12B on chromosome 5q33-34.

Holm P; Luthman H; Kockum I
Letter: DIABETOLOGIA. 1997;40(11):1366-1367

Preliminary data on a genome search in NIDDM siblings: the NIDDM1 locus on chromosome 2 is not linked to NIDDM in the Sardinian population. Study Group for the Genetics of Diabetes in Sardinia.

Ciccarese M; Tonolo G; Delin I; Wong FK; Holm P; Atzeni MM; Lichtenstein P; Kockum I; Maioli M; Luthman H
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Employments

Research Coordinator, Department of Medicine, Karolinska Institutet, 2010-

Degrees and Education

Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2003

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Degrees and Education

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