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About me

After completing my PhD degree in 2007 at Lund University in Sweden I started working as an embryologist at the Fertility Unit at Karolinska University Hospital in Sweden. I was working there until I joined Dr. Outi Hovatta's lab in 2010 at CLINTEC,  Karolinska Institutet, Sweden. I was working as a Lab Manager for Dr. Hovatta until I started working in Dr. Fredrik Lanner's lab in 2016.

 

Currently I work as a Lab Manager in the Lanner lab at CLINTEC, Karolinska Institutet.

Research description

Human embryonic stem cells (hESCs) are a promising cell source for therapies in regenerative medicine. However, traditional culture conditions include undefined and animal-derived components, making the cells suboptimal for clinical use. High-quality hESC derived under GMP (Good Manufacturing Practice) conditions, is crucial for clinical translation.

 

Based on previous work where we have published xeno-free and defined protocols for derivation and culture (Nature comm 2014, Nature prot 2014) we have now established a clinically compliant GMP protocol for hESC derivation.  This new protocol is validated and the new system achieves a good derivation efficiency. The purpose is to establish a bank of cells to be able to distribute hESCs of clinical GMP standard for use in regenerative medicine.

 

We have now initiated the GMP production using this protocol and anticipate to have our first lines established during 2017.

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