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Karin Palmblad

Associated

Visiting address : Karolinska Universitetssjukhuset, Q2:07 17176 Stockholm, Sweden
Postal address : Department of Women's and Children's Health (KBH), K6, Division of Pediatric Neurology, Karolinska Universitetssjukhuset, Q2:07 17176 Stockholm, Sweden
Delivery address : Karolinska Universitetssjukhuset, Q2:07 17176 Stockholm, Sweden

Publications

An in vivo cross-linkable hyaluronan gel with inherent anti-inflammatory properties reduces OA cartilage destruction in female mice subjected to cruciate ligament transection
Aulin C, Lundbäck P, Palmblad K, Klareskog L, Erlandsson Harris H
Osteoarthritis and cartilage 2017;25(1):157-165

A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice
Lundbäck P, Lea Jd, Sowinska A, Ottosson L, Fürst Cm, Steen J, et al
Hepatology (Baltimore, Md.) 2016;64(5):1699-1710

High systemic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome
Palmblad K, Schierbeck H, Sundberg E, Horne Ac, Harris He, Henter Ji, et al
Molecular medicine (Cambridge, Mass.) 2015;20():538-47

Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis
Agalave Nm, Larsson M, Abdelmoaty S, Su J, Baharpoor A, Lundbäck P, et al
Pain 2014;155(9):1802-13

TLR4 as receptor for HMGB1 induced muscle dysfunction in myositis
Zong M, Bruton Jd, Grundtman C, Yang H, Li Jh, Alexanderson H, et al
Annals of the rheumatic diseases 2013;72(8):1390-9

Pro-Inflammatory Cytokines Produced by Growth Plate Chondrocytes May Act Locally to Modulate Longitudinal Bone Growth
Fernandez-vojvodich P, Palmblad K, Karimian E, Andersson U, Savendahl L
HORMONE RESEARCH IN PAEDIATRICS 2012;77(3):180-7

Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis
Zickert A, Palmblad K, Sundelin B, Chavan S, Tracey Kj, Bruchfeld A, et al
Arthritis research & therapy 2012;14(1):R36-

High-Mobility Group Box-1 Protein (HMGB1) Is Increased in Antineutrophilic Cytoplasmatic Antibody (ANCA)-Associated Vasculitis with Renal Manifestations
Bruchfeld A, Wendt M, Bratt J, Qureshi Ar, Chavan S, Tracey Kj, et al
MOLECULAR MEDICINE 2011;17(1-2):29-35

High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts
Wahamaa H, Schierbeck H, Hreggvidsdottir Hs, Palmblad K, Aveberger Ac, Andersson U, et al
ARTHRITIS RESEARCH & THERAPY 2011;13(4):R136-

Monoclonal Anti-HMGB1 (High Mobility Group Box Chromosomal Protein 1) Antibody Protection in Two Experimental Arthritis Models
Schierbeck H, Lundback P, Palmblad K, Klevenvall L, Erlandsson-harris H, Andersson U, et al
MOLECULAR MEDICINE 2011;17(9-10):1039-44

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release
Yang Ha, Hreggvidsdottir Hs, Palmblad K, Wang Hc, Ochani M, Li Jh, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2010;107(26):11942-7

Protective Targeting of High Mobility Group Box Chromosomal Protein 1 in a Spontaneous Arthritis Model
Ostberg T, Kawane K, Nagata S, Yang Ha, Chavan S, Klevenvall L, et al
ARTHRITIS AND RHEUMATISM 2010;62(10):2963-72

Highly Arthritis-susceptible DA Rats Express IL-1 beta in Articular Cartilage
Weiss Rj, Harris He, Palmblad K
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2009;69(3):188-93

High mobility group box chromosomal protein 1 acts as a proliferation signal for activated T lymphocytes
Sundberg E, Fasth Aer, Palmblad K, Harris He, Andersson U
IMMUNOBIOLOGY 2009;214(4):303-9

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation
Hreggvidsdottir Hs, Ostberg T, Wahamaa H, Schierbeck H, Aveberger Ac, Klevenvall L, et al
JOURNAL OF LEUKOCYTE BIOLOGY 2009;86(3):655-62

Gait pattern in rheumatoid arthritis
Weiss Rj, Wretenberg P, Stark A, Palmblad K, Larsson P, Grondal L, et al
GAIT & POSTURE 2008;28(2):229-34

HMGB1 enhances TLR ligand-induced cytokine production by complex formation
Hreggvidsdottir H, Ostberg T, Schierbeck H, Ottoson L, Palmblad K, Aveberger Ac, et al
JOURNAL OF LEUKOCYTE BIOLOGY 2008;84(2):A25-A25

HMGB1 is involved in the pathogenesis of a novel spontaneous arthritis model
Ostberg T, Palmblad K, Klevenvall L, Yang H, Kawane K, Nagata S, et al
JOURNAL OF LEUKOCYTE BIOLOGY 2008;84(2):A32-A32

Oxaliplatin retains HMGB1 intranuclearly and ameliorates collagen type II-induced arthritis
Ostberg T, Wahamaa H, Palmblad K, Ito N, Stridh P, Shoshan M, et al
ARTHRITIS RESEARCH & THERAPY 2008;10(1):R1-

Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis
Palmblad K, Sundberg E, Diez M, Soderling R, Aveberger Ac, Andersson U, et al
ARTHRITIS RESEARCH & THERAPY 2007;9(2):R35-

The novel inflammatory cytokine high mobility group box protein 1 (HMGB1) is expressed by human term placenta
Holmlund U, Wahamaa H, Bachmayer N, Bremme K, Sverremark-ekstrom E, Palmblad K
IMMUNOLOGY 2007;122(3):430-7

High mobility group box-1 (HMGB1) augments pancreatic necrosis in taurocholate induced pancreatitis in rats
Segersvard R, Palmblad K, Tsai J, Capitano A, Andersson U, Permert J
PANCREAS 2006;33(4):497-497

Orthopaedic surgery of the lower limbs in 49 802 rheumatoid arthritis patients: results from the Swedish National Inpatient Registry during 1987 to 2001
Weiss Rj, Stark A, Wick Mc, Ehlin A, Palmblad K, Wretenberg P
ANNALS OF THE RHEUMATIC DISEASES 2006;65(3):335-41

Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity
Lundberg K, Nijenhuis S, Vossenaar Er, Palmblad K, Van Venrooij Wj, Klareskog L, et al
ARTHRITIS RESEARCH & THERAPY 2005;7(3):R458-67

CNI-1493, an inhibitor of proinflammatory cytokines, retards cartilage destruction in rats with collagen induced arthritis
Larsson E, Harris He, Palmblad K, Mansson B, Saxne T, Klareskog L
ANNALS OF THE RHEUMATIC DISEASES 2005;64(3):494-6

Morphological characterization of receptor activator of NF kappa B ligand (RANKL) and IL-1 beta expression in rodent collagen-induced arthritis
Weiss Rj, Harris He, Wick Mc, Wretenberg P, Stark A, Palmblad K
SCANDINAVIAN JOURNAL OF IMMUNOLOGY 2005;62(1):55-62

Morphological studies of receptor activator of NF-KAPPA-B ligand (RANKL), IL-17, and IL-1-beta expression in rodent collagen-induced arthritis
Weiss Rj, Erlandsson-harris H, Wick Mc, Wretenberg Pf, Stark A, Palmblad K
ANNALS OF THE RHEUMATIC DISEASES 2004;:153-153

Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity
Kokkola R, Li J, Sundberg E, Aveberger Ac, Palmblad K, Yang H, et al
ARTHRITIS AND RHEUMATISM 2003;48(7):2052-8

High mobility group box chromosomal protein 1 - A novel proinflammatory mediator in synovitis
Kokkola R, Sundberg E, Ulfgren Ak, Palmblad K, Li J, Wang H, et al
ARTHRITIS AND RHEUMATISM 2002;46(10):2598-603

Dynamics of early synovial cytokine expression in rodent collagen-induced arthritis - A therapeutic study using a macrophage-deactivating compound
Palmblad K, Erlandsson-harris H, Tracey Kj, Andersson U
AMERICAN JOURNAL OF PATHOLOGY 2001;158(2):491-500

IFN-alpha beta-dependent, IFN-gamma secretion by bone-marrow-derived macrophages controls an intracellular bacterial infection
Rothfuchs Ag, Gigliotti D, Palmblad K, Andersson U, Wigzell H, Rottenberg Me
JOURNAL OF IMMUNOLOGY 2001;167(11):6453-61

High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
Andersson U, Wang Hc, Palmblad K, Aveberger Ac, Bloom O, Erlandsson-harris H, et al
JOURNAL OF EXPERIMENTAL MEDICINE 2000;192(4):565-70

Identification of rat IL-1 beta, IL-2, IFN-gamma and TNF-alpha in activated splenocytes by intracellular immunostaining
Palmblad K, Andersson U
BIOTECHNIC & HISTOCHEMISTRY 2000;75(3):101-9

Anti-inflammatory effects of a TNF-alpha inhibitor (CNI-1493) in collagen-induced arthritis in rats
Harris He, Akerlund K, Tracey Kj, Wang H, Fehniger T, Klareskog L, et al
EUROPEAN CYTOKINE NETWORK 1998;9(3):489-489

Targeted suppression of cytokine production in monocytes but not in T lymphocytes by a tetravalent guanylhydrazone (CNI-1493)
Bjork L, Tracey Kj, Ulrich P, Bianchi M, Cohen Ps, Akerlund K, et al
JOURNAL OF INFECTIOUS DISEASES 1997;176(5):1303-12

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