Senior research fellow, clin.
I am a hand surgeon and a pediatric orthopaedic surgeon working at the Dept of Pediatric Orthopaedic Surgery at the Karolinska University Hospital. Clinically, my main interests are cerebral palsy, arthrogryposis (AMC), limb deficiencies, spina bifida (MMC), developmental dysplasia of the hip (DDH) and trauma. My PhD from 2004 investigated tendon transfer mechanics and properties of spastic muscle.
Our main research focus is to explore dynamic adaptations of the muscle in cerebral palsy on molecular, cellular and functional levels, with special emphasis on the mechanisms of contracture formation and the influence of treatments.
The group includes
Eva Pontén MD PhD, orthopaedic surgeon and hand surgeon
Ferdinand von Walden, MD, PhD, post doc
Stefan Gantelius, MD, PhD student, orthopaedic surgeon
Immobilization of the rabbit tibialis anterior muscle in a lengthened position causes addition of sarcomeres in series and extra-cellular matrix proliferation
JOURNAL OF BIOMECHANICS 2008;41(8):1801-4
[Upper extremity botulinum toxin treatment in cerebral palsy. Treatment guidelines the first step towards national cooperation]
Decreased capillarization and a shift to fast myosin heavy chain IIx in the biceps brachii muscle from young adults with spastic paresis
JOURNAL OF THE NEUROLOGICAL SCIENCES 2007;253(1-2):25-33
Intraoperative muscle measurements reveal a relationship between contracture formation and muscle remodeling
MUSCLE & NERVE 2007;36(1):47-54
Spastic wrist flexors are more severely affected than wrist extensors in children with cerebral palsy
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY 2005;47(6):384-9
Effect of muscle tension during tendon transfer on sarcomerogenesis in a rabbit model
JOURNAL OF HAND SURGERY-AMERICAN VOLUME 2000;25A(1):138-43
Sarcomere length changes after flexor carpi ulnaris to extensor digitorum communis tendon transfer
JOURNAL OF HAND SURGERY-AMERICAN VOLUME 1996;21A(4):612-8