High impact publications

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Recent publications with one or several authors from Department of Medicine, Huddinge in high impact journals.

Soo Aleman, Enheten för inflammation, gastroenterologi och reumatologi

Diabetes and Cirrhosis Are Risk Factors for Hepatocellular Carcinoma After Successful Treatment of Chronic Hepatitis C.
Hedenstierna M, Nangarhari A, Weiland O, Aleman S
Clin. Infect. Dis. 2016 Sep;63(6):723-9


Johan K. Sandberg, Edwin Leeansyah, Center for Infectious Medicine

Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion.
Paquin-Proulx D, Gibbs A, Bächle S, Checa A, Introini A, Leeansyah E, et al
J. Immunol. 2016 Sep;197(5):1843-51


Johan K. Sandberg, Edwin Leeansyah, Center for Infectious Medicine

MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation.
Gibbs A, Leeansyah E, Introini A, Paquin-Proulx D, Hasselrot K, Andersson E, et al
Mucosal Immunol 2016 Apr;():


Mikael Rydén, Peter Arner, Unit for Endocrinology and Diabetes

The Adipose Transcriptional Response to Insulin Is Determined by Obesity, Not Insulin Sensitivity


Anders Sönnerborg, Unit for Infection and Dermatology:

Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe.

Hofstra LM, Sauvageot N, Albert J, Alexiev I, Garcia F, Struck D, Van de Vijver DA, Åsjö B, Beshkov D, Coughlan S, Descamps D, Griskevicius A, Hamouda O, Horban A, Van Kasteren M, Kolupajeva T, Kostrikis LG, Liitsola K, Linka M, Mor O, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Staneková D, Stanojevic M, Van Laethem K, Zazzi M, Zidovec Lepej S, Boucher CA, Schmit JC, Wensing AM; SPREAD Program.

Clin Infect Dis. 2016 Mar 1;62(5):655-63. doi: 10.1093/cid/civ963. Epub 2015 Nov 29.


Jenny Mjösberg, Center for Infectious Medicine:

The heterogeneity of human CD127(+) innate lymphoid cells revealed by single-cell RNA sequencing.
Björklund , Forkel M, Picelli S, Konya V, Theorell J, Friberg D, et al
Nat. Immunol. 2016 Apr;17(4):451-60.


Anders Sönnerborg, Amanda Häggblom, Enheten för infektionssjukdomar och hud:

Factors influencing the efficacy of rilpivirine in HIV-1 subtype C in low- and middle-income countries.
Neogi U, Häggblom A, Singh K, Rogers L, Rao S, Amogne W, et al
J. Antimicrob. Chemother. 2016 Feb;71(2):367-71.


Anders Sönnerborg, Amanda Häggblom, Enheten för infektionssjukdomar och hud:

Häggblom A, Svedhem V, Singh K, Sönnerborg A, Neogi U. Viral failure in HIV-1 subtype C infected patients receiving anti-retroviral therapy in a national health care setting: A real-life prospective cohort study. Lancet HIV 2016.


Anders Sönnerborg, Enheten för infektionssjukdomar och hud:

Noguera-Julian M, Rocafort M, Guillén Y, Rivera J, Casadellà M, Nowak P, Hildebrand F, Zeller G, Parera M, Bellido R, Rodríguez C, Carrillo J, Mothe B, Coll J, Bravo I, Estany C, Herrero C, Saz J, Sirera G, Torrela A, Navarro J, Crespo M, Brander C, Negredo E, Blanco J, Guarner F, Luz Calle M, Bork P, Sönnerborg A, Clotet B, Paredes R. Gut microbiota linked to sexual practice and HIV infection. eBiomedicine 2016


Anders Sönnerborg, Enheten för infektionssjukdomar och hud:

Gupta R Sönnerborg A for the TenoRes collaboration. Global epidemiology of drug resistance following failure of WHO recommended first line regimens for adult HIV-1 infection – a multicenter retrospective cohort study. Lancet Infectious Diseases 2016, http://dx.doi.org/10.1016/S1473-3099(15)00536


Per Ljungman, Unit of Hematology:

Immunogenicity, safety, and tolerability of 13-valent pneumococcal conjugate vaccine followed by 23-valent pneumococcal polysaccharide vaccine in recipients of allogeneic hematopoietic stem cell transplant aged ≥2 years: an open-label study.
Cordonnier C, Ljungman P, Juergens C, Maertens J, Selleslag D, Sundaraiyer V, et al
Clin. Infect. Dis. 2015 Aug;61(3):313-23


Per Ljungman, Unit of Hematology:

Stem cell transplantation in severe congenital neutropenia: an analysis from the European Society for Blood and Marrow Transplantation.
Fioredda F, Iacobelli S, van Biezen A, Gaspar B, Ancliff P, Donadieu J, et al
Blood 2015 Oct;126(16):1885-92; quiz 1970


Hareth Nahi, Center for Hematology and Regenerative Medicine:

Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma.
Lokhorst H, Plesner T, Laubach J, Nahi H, Gimsing P, Hansson M, et al
N. Engl. J. Med. 2015 Sep;373(13):1207-19


Mattias Svensson, Center for Infectious Medicine:

Tissue-infiltrating neutrophils represent the main source of IL-23 in the colon of patients with IBD.
Kvedaraite E, Lourda M, Ideström M, Chen P, Olsson-Åkefeldt S, Forkel M, et al
Gut 2016 Oct;65(10):1632-41.


Susanna Brighenti och Jagadees Rao Muvva, Center for Infectious Medicine:

Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages.
Rekha R, Rao Muvva S, Wan M, Raqib R, Bergman P, Brighenti S, et al
Autophagy 2015 ;11(9):1688-99.


Mikael Rydén, Peter Arner, Daniel P Andersson, Erik Arner, Yvonne Widlund, Niklas Mejhert, Unit of Endocrinology with the Lipid laboratory:

 Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis.
Rydén M, Uzunel M, Hård J, Borgström E, Mold J, Arner E, et al
Cell Metab. 2015 Sep;22(3):408-17


Hannes Hagström, Per Stål och Rolf Hultcrantz, Unit of Gastroenterology and Rheumatology:

 Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up.
Ekstedt M, Hagström H, Nasr P, Fredrikson M, Stål P, Kechagias S, et al
Hepatology 2015 May;61(5):1547-54


Dina Melki and Tomas Jernberg, Unit of Heart and Lung Diseases:

Implications of introducing high-sensitivity cardiac troponin T into clinical practice
Melki D, Lugnegård J, Alfredsson J, Lind S, Eggers KM, Lindahl B, Jernberg T.
J Am Coll Cardiology (2015) Online 20 April. Original investigation.

Hans-Gustaf Ljunggren and Yenan Bryceson, Center for Infectious Medicine:

Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function
Schlums H, Cichocki F, Tesi B, Theorell J, Beziat V, Holmes TD, Han H, Chiang SCC, Foley B, Mattsson K, Larsson S, Schaffer M, Malmberg K-J, Ljunggren H-G, Miller JS, Bryceson YT.
Immunity (2015) Online 17 March. Article.

Karolina Szummer, Unit of Heart and Lung Diseases:

Association between the use of fondaparinux vs low-molecular-weight heparin and clinical outcomes in patients with non-ST-segment elevation myocardial infarction.
Szummer K, Oldgren J, Lindhagen L, Carrero J, Evans M, Spaak J, et al
JAMA 2015 Feb;313(7):707-16


Professor Johan Sandberg, Center for Infectious Medicine:

HIV Type 1 Disease Progression to AIDS and Death in a Rural Ugandan Cohort Is Primarily Dependent on Viral Load Despite Variable Subtype and T-Cell Immune Activation Levels.
Eller M, Opollo M, Liu M, Redd A, Eller L, Kityo C, et al
J. Infect. Dis. 2015 May;211(10):1574-84


Professor Anders Sönnerborg, Unit of Infectious Diseases and Dermatology:

Occasional spontaneous clearance of chronic hepatitis C virus in HIV-infected individuals.
Stenkvist J, Nyström J, Falconer K, Sönnerborg A, Weiland O
J. Hepatol. 2014 Oct;61(4):957-61

Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure in Indian patients.
Neogi U, Rao S, Bontell I, Verheyen J, Rao V, Gore S, et al
AIDS 2014 Sep;28(15):2319-22


Professor Ola Weiland, Unit of Infectious Diseases and Dermatology:

ABT-450, ritonavir, ombitasvir, and dasabuvir achieves 97% and 100% sustained virologic response with or without ribavirin in treatment-experienced patients with HCV genotype 1b infection.
Andreone P, Colombo M, Enejosa J, Koksal I, Ferenci P, Maieron A, et al
Gastroenterology 2014 Aug;147(2):359-365.e1

Patient-reported outcomes assessment in chronic hepatitis C treated with sofosbuvir and ribavirin: the VALENCE study.
Younossi Z, Stepanova M, Zeuzem S, Dusheiko G, Esteban R, Hezode C, et al
J. Hepatol. 2014 Aug;61(2):228-34