AMORIScancer: Metabolic Profiles and Cancer

The aim of this project is to examine the role of metabolic markers in the risk of developing cancer; including glucose, triglycerides, total cholesterol, HDL, LDL, apolipoprotein A-I and B, and GGT.

Project description

Background: There is some evidence that glucose and lipid metabolism influences tumour development. Few observational studies to date have in detail studied associations between metabolic profiles and cancer risk.

Project goals/aims: To examine possible associations between metabolic profiles and cancer risk and prognosis.

Material: The Swedish Apolipoprotein MORtality RISk data-base (AMORIS) includes blood samples from more than 600,000 persons from the Stockholm area between 1985 and 1996. Record linkages have provided additional information on socioeconomic factors, reproductive history, vital status, cancer diagnosis and emigration.

Project leaders

Adjunct professor

Niklas Hammar

Phone: +46-(0)553-296 49
Organizational unit: Epidemiology
E-mail: Niklas.Hammar@ki.se

Associated

Göran Wallin

Organizational unit: Endocrine Surgery
E-mail: Goran.Wallin@ki.se

Professor

Mats Lambe

Phone: +46-(0)8-524 861 64
Organizational unit: Department of Medical Epidemiology and Biostatistics (MEB), C8
E-mail: Mats.Lambe@ki.se

Project period: 2008-ongoing
Main financing: KI Research Funds (M Lambe). The Swedish Cancer Society (N Hammar).

Publications