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Imaging core facilities

Karolinska Institutet offers a wide range of imaging infrastructures. Our facilities collaborate closely with other world-leading centres to ensure that we stay in the front-line of the field.

Biomedicum Imaging Core

Photo: Shigeaki Kanatani

Biomedicum Imaging Core Karolinska Institutet (BIC) is a close collaboration between two cell imaging core-facilities at KI Campus Solna (north) – the CLICK facility and the CMB microscope facility. These core facilities are equipped with top-notch imaging systems suitable for live cell time-lapse, deep tissue, ion, spectral, confocal or general fluorescence imaging, and much more.

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Cryo Electron Microscopy Facility

The objective of the high resolution electron microscopy core facility is to provide a seamless facility for general EM, cryoEM and high resolution studies of biological specimens. The facility is being located in the Novum building, Flemingsberg at KI’s south campus.

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Electron Tomography

To understand the life processes it is necessary to know where the specific macromolecules are located within a cell and tissue and how the macromolecules interact with each other. Core Facility for Electron Tomography permits subcellular and macromolecular assemblies to be studied in three dimensions.

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Electron Microscopy Unit

The Electron Microscopy Unit (EMil) offers conventional preparation for TEM and SEM, as well as preparation for immunohistochemistry, morphometric analysis, and low temperature techniques such as low temperature embedding, high pressure freezing and cryosectioning (Tokuyasu method).

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Live Cell Imaging Core Facility

Mikaela Wiking-Differentiated cellsAdvanced light microscopy facility with top-of-the-line widefield, confocal and light sheet microscopes. At the Live Cell Imaging Core Facility (LCI) you can laser-capture bits of tissues, print protein micropatterns, you can choose to run ultra-fast imaging, spectral detection, multiphoton excitation, FLIM measurements, long term live cell imaging, high throughput pipelines... The LCI facility puts education of researchers at the core of its activities with extensive user training and in-depth yearly microscopy course.

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MR Center KI/SLL

The MR Research Center is a core facility that handles the MR Research capacity at the Neuroradiology Clinic, Karolinska University Hospital. The present capacity is 1 full time 3T Karolinska Institutet owned GE 750 and 2 off office hours 1.5 T GE instruments. All of them have fMRI, DTI and other research capacities.

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National Facility for Magnetoencephalography

The Swedish National Facility for Magnetoencephalography (NatMEG) is the first and only research laboratory in Sweden for whole-head measurements of neuronal brain activity using magnetoencephalography (MEG). NatMEG regularly arranges activities such as invited talks, symposium, analysis workshops and user training.

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Preclinical Imaging Facility

This is a small animal imaging hub at Flemingsberg campus, and a part of the Preclinical Laboratory (PKL). Preclinical Imaging Facility (PIF) together with PKL provides a full range of preclinical study services for academia and industry sectors, providing them with high quality preclinical study data.

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Stockholm Medical Image Laboratory and Education

The Stockholm Medical Image Laboratory and Education (SMILE) is a joint core facility of Karolinska Institutet and Karolinska University Hospital, with the purpose to facilitate evaluation of medical digital images, irrespective of source. SMILE is the translational hub where clinicians, researchers and doctoral students from academy, healthcare and industry meet and benefit from the collected competence in image analysis, visualization and quantification. While using the images, tools and innovations for improved diagnostics and patient care, near collaboration with medtech companies is a prerequisite.

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