Karolinska Institutet Discovers - Agneta Åkesson, IMM
Associate Professor Agneta Åkesson, Institute of Environmental Medicine (IMM), will present the research behind her latest publication:
Low-risk diet and lifestyle habits in the primary prevention of myocardial infarction in men: a population-based prospective cohort study.
J. Am. Coll. Cardiol. 2014 Sep;64(13):1299-306
Coffee and lunch wrap will be served between 11:30 and 12:00. First come, first served. No registration needed.
Ischemic heart disease incidence and mortality have decreased in many areas of the world, yet the global burden of disease remains very high. Because population-wide strategies to shift the entire distribution of risk cannot rely on prescription medication, effective lifestyle-based prevention is essential. The aim of this study was to examine the benefit of combined low-risk diet and healthy lifestyle habits on the incidence of myocardial infarction (MI) in Swedish middle-aged and elderly men. We followed 20,721 healthy men and 7,139 men with diagnosis of hypertension and high cholesterol level from baseline (in 1998) through 2009 and ascertained 1361 and 765 events of MI in these men, respectively. The low-risk behavior included 5 factors: a healthy diet, moderate alcohol consumption, no smoking, being physically active and having no abdominal adiposity. There were clear associations with lower risk of MI for each individual lifestyle factor the participants practiced. Men who were non-smokers, walked or cycled for at least 40 minutes per day, exercised at least one hour per week, had a waist circumference below 95 centimeters, consumed moderate amounts of alcohol, and followed a healthy diet (regular consumption of fruits, vegetables, legumes, nuts, reduced-fat dairy products, whole grains and fish) at baseline had 86% lower risk. Similar findings were observed in men with hypertension and high cholesterol levels. Thus, a combination of healthy behaviors may prevent most MI events in our study. This behavior was only present in 1% of the study population.