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Neuropsykofarmakologi

Vi forskar på biogeniska aminer i hjärnan: molekylär biologi, biokemi och fysiologi, med särskild betoning på läkemedelsutveckling inom neuropsykofarmakologi.

Gruppmedlemmar

Joseph Bruton – Forskare

Kent Jardemark – Forskare

Monica Marcus – Senior lab manager

Torgny Svensson – Professor, senior

Joep Titulaer – Anknuten  

Senaste publikationer

Role of concomitant inhibition of the norepinephrine transporter for the antipsychotic effect of quetiapine.
Björkholm C, Jardemark K, Marcus MM, Malmerfelt A, Nyberg S, Schilström B, et al
Eur Neuropsychopharmacol 2013 Jul;23(7):709-20

Celecoxib enhances the effect of reboxetine and fluoxetine on cortical noradrenaline and serotonin output in the rat.
Johansson D, Falk A, Marcus MM, Svensson TH
Prog. Neuropsychopharmacol. Biol. Psychiatry 2012 Oct;39(1):143-8

Involvement of 5-HT2A receptor and α2-adrenoceptor blockade in the asenapine-induced elevation of prefrontal cortical monoamine outflow.
Frånberg O, Marcus MM, Svensson TH
Synapse 2012 Jul;66(7):650-60

Augmentation by escitalopram, but not citalopram or R-citalopram, of the effects of low-dose risperidone: behavioral, biochemical, and electrophysiological evidence.
Marcus MM, Jardemark K, Malmerfelt A, Gertow J, Konradsson-Geuken A, Svensson TH
Synapse 2012 Apr;66(4):277-90

Differential effects of AMPA receptor potentiators and glycine reuptake inhibitors on antipsychotic efficacy and prefrontal glutamatergic transmission.
Jardemark K, Marcus MM, Malmerfelt A, Shahid M, Svensson TH
Psychopharmacology (Berl.) 2012 May;221(1):115-31

Smoking, quitting, and psychiatric disease: a review.
Aubin HJ, Rollema H, Svensson TH, Winterer G
Neurosci Biobehav Rev 2012 Jan;36(1):271-84

Effects of S-citalopram, citalopram, and R-citalopram on the firing patterns of dopamine neurons in the ventral tegmental area, N-methyl-D-aspartate receptor-mediated transmission in the medial prefrontal cortex and cognitive function in the rat.
Schilström B, Konradsson-Geuken A, Ivanov V, Gertow J, Feltmann K, Marcus MM, et al
Synapse 2011 May;65(5):357-67

Deuterium substitutions in the L-DOPA molecule improve its anti-akinetic potency without increasing dyskinesias.
Malmlöf T, Rylander D, Alken RG, Schneider F, Svensson TH, Cenci MA, et al
Exp. Neurol. 2010 Oct;225(2):408-15

Effects of asenapine on prefrontal N-methyl-D-aspartate receptor-mediated transmission: involvement of dopamine D1 receptors.
Jardemark K, Marcus MM, Shahid M, Svensson TH
Synapse 2010 Nov;64(11):870-4

Reboxetine enhances the olanzapine-induced antipsychotic-like effect, cortical dopamine outflow and NMDA receptor-mediated transmission.
Marcus MM, Jardemark K, Malmerfelt A, Björkholm C, Svensson TH
Neuropsychopharmacology 2010 Aug;35(9):1952-61

Kontakt

Torgny Svensson

Professor, senior
Svensson Torgny grupp - Neuropsykofarmakologi
Institutionen för fysiologi och farmakologi (FYFA), C3