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Molekylär cancer- och stamcellsbehandling

Information om forskningen i vår grupp finns på engelska.

Gruppmedlemmar

Ewa KurzejamskaForskare
Varsha PrakashDoktorand
Theresa VincentForskargruppsledare

Gruppmedlemmar utanför KI

Linda Bojmar Doktorand, bihandledning tillsammans med Dr Lyden, Weill Cornell Medical College of Cornell University
Randall Dass Doktorand, bihandledning tillsammans med Dr Blanchard, Weill Cornell Medical College of Cornell University, USA

Alumni

  • Jacob Jansson
  • Iris Muller
  • Tianyi Song
  • Rithika Venkatesh
  • Joel Östblom

Anslagsgivare

Samarbeten

Theresa Vincents forskargrupp vid Uppsala universitet, Immunologi, genetik och patologi, IGP

Theresa Vincent profilsida vid Department of Physiology and Biophysics, Cornell University, Weill Cornell Medical College, New York, USA.

Press

Närkoll på Ribosomerna. Medicinsk Vetenskap nr 2 2018 (sid. 13)

Därför skyddar särskild gen mot aggressiv bröstcancer. Nyhet från KI. 2016-08-07.

Utvalda publikationer

Endogenous rRNA Sequence Variation Can Regulate Stress Response Gene Expression and Phenotype
Kurylo CM, Parks MM, Juette MF, Zinshteyn B, Altman RB, Thibado JK, Vincent T, Blanchard SC
Cell Reports Vol. 25 Issue 1, (2018) Oct 2

Face morphogenesis is promoted by Pbx-dependent EMT via regulation of Snail1 during frontonasal prominence fusion.
Losa M, Risolino M, Li B, Hart J, Quintana L, Grishina I, et al
Development 2018 03;145(5):

Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression.
Parks M, Kurylo C, Dass R, Bojmar L, Lyden D, Vincent C, et al
Sci Adv 2018 Feb;4(2):eaao0665

EMT, inflammation and metastasis.
Vincent C, Fuxe J
Semin. Cancer Biol. 2017 12;47():168-169

27527752

Membrane depolarizing channel blockers induce selective glioma cell death via impaired nutrient transport and unfolded protein / amino acid responses.
Niklasson M, Maddalo G, Zuzana Sramkova Z, Mutlu E, Wee S, Sekyrova S, Schmidt L, Fritz N, Ivar Dehnisch I, Kyriatzis G, Krafcikova M, Carson BBC, Feenstra J, Marinescu V, Segerman A, Mulder J, Haraldsson M, Gustavsson AL, Hammarström L, Jenmalm, Jensen A, Uhrbom L, Altelaar A.F. M, Linnarsson S, Uhlén P, Trantirek L, Vincent CT, Nelander S, Per Øyvind Enger PO, Andäng M.
Cancer Res. (2017) Jan 13

27500936

Functional Dynamics within the Human Ribosome Regulate the Rate of Active Protein Synthesis.
Ferguson A, Wang L, Altman R, Terry D, Juette M, Burnett B, et al
Molecular Cell. 2015, 60:1–12

23818587

19597490

18490923

Neutralized adenovirus-immune complexes can mediate effective gene transfer via an Fc receptor-dependent infection pathway.
Leopold P, Wendland R, Vincent T, Crystal R
J. Virol. 2006 Oct;80(20):10237-47

Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells.
Vincent T, Pettersson RF, Crystal RG, Leopold PL.
J Virol. (2004) 78:8047-58.

Rapid assessment of adenovirus serum neutralizing antibody titer based on quantitative, morphometric evaluation of capsid binding and intracellular trafficking: population analysis of adenovirus capsid association with cells is predictive of adenovirus infectivity.
Vincent T, Harvey B, Hogan S, Bailey C, Crystal R, Leopold P
J. Virol. 2001 Feb;75(3):1516-21

Enhanced liver uptake of opsonized red blood cells after in vivo transfer of FcgammaRIIA cDNA to the liver.
Bezdicek P, Worgall S, Kovesdi I, Kim M, Park J, Vincent T, et al
Blood 1999 Nov;94(10):3448-55

Review

Transcriptional crosstalk between TGF-β and stem cell pathways in tumor cell invasion: role of EMT promoting Smad complexes.
Fuxe J, Vincent T, Garcia de Herreros A
Cell Cycle 2010 Jun;9(12):2363-74

22613484

22819801

22863889

Publicerade kommentarer på gruppens vetenskapliga artiklar

News and Views on; Transcriptional crosstalk between TGF-β and stem cell pathways in tumor cell invasion: role of EMT promoting Smad complexes.
Cell Cycle (2010) 12: 2363-2374

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Kontakta forskargruppsledaren

Forskargruppsledare

Theresa Vincent

Enhet: Vincent Teresa grupp - Molekylär cancer- och stamcellsbehandling
E-post: theresa.vincent@ki.se