Toppublikationer

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Forskare vid Karolinska Institutet publicerar ungefär 4 700 vetenskapliga artiklar med originalresultat om året. Här listas aktuella publikationer i högt rankade vetenskapliga tidskrifter (impaktfaktor 15 och uppåt) där KI-forskare medverkar.

180214
A molecular atlas of cell types and zonation in the brain vasculature
Vanlandewijck M, He L, Andaloussi Mäe M, Andrae J, Ando K, Del Gaudio F, Nahar K, Lebouvier T,  Laviña B, Gouveia L, Sun Y, Raschperger E, Räsänen M, Zarb Y, Mochizuki N, Keller A, Lendahl UBetsholtz C
Nature (2018) Online 14 February. Article.
På KI Nyheter: Karta över hjärnans blodkärl ger nya ledtrådar om hjärnsjukdomar

180214
Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy
Stafford WC, Peng X, Hägg Olofsson M, Zhang X, Luci DK, Lu L, Cheng Q, Trésaugues L, Dexheimer TS, Coussens NP, Augsten M, Martinsson Ahlzén HS, Orwar O, Östman A, Stone-Elander S, Maloney DJ, Jadhav A, Simeonov A, Linder S, Arnér ESJ
Science Translational Medicine (2018) Online 14 February, Research Article.
På KI Nyheter: Ny möjlig princip för cancerterapi

180213
Outcome measures in coeliac disease trials: the Tampere recommendations
Ludvigsson JF, Ciacci C, Green PH et al.
Gut (2018) Online 13 February. Original Article.

180209
Toward an optically controlled brain
Feliu N, Neher E, Parak WJ
Science (2018) Online 9 February. Perspective.

180208
Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells
Soon Heng Tan C, Diam Go K, Bisteau X, Dai L, Han Yong C, Prabhu N, Burak Ozturk M, Ting Lim Y,  Sreekumar L, Lengqvist J, Tergaonkar V, Kaldis P, Sobota RM, Nordlund P
Science (2018) Online 8 February. Report.

180208
Five and 10 minute Apgar scores and risks of cerebral palsy and epilepsy: population based cohort study in Sweden
Persson M, Razaz N, Tedroff K, Joseph KS, Cnattingius S
BMJ (2018) Online 8 February. Research.
På KI Nyheter: Apgarpoäng hos nyfödda förutsäger risk för CP och epilepsi

180206
Kynurenic acid and GPR35 regulate adipose tissue energy homeostasis and inflammation
Agudelo LZ, Ferreira DMS, Cervenka I, Bryzgalova G, Dadvar S, Jannig PR, Pettersson-Klein AT, Lakshmikanth T, Sustarsic EG, Porsmyr-Palmertz M, Correia JC, Izadi M, Martínez-Redondo V, Ueland PM, Midttun Ø, Gerhart-Hines Z, Brodin P, Pereira T, Berggren PO, Ruas JL.
Cell Metabolism (2018) Online 6 February. Article.
På KI Nyheter: Därför ger motion en sund själ i en sund kropp

180130
Helicobacter pylori eradication treatment and the risk of gastric adenocarcinoma in a Western population
Doorakkers E, Lagergren J, Engstrand L, Brusselaers N
Gut (2018) Online 30 January. Original Article.

180124
Genetically modified lentiviruses that preserve microvascular function protect against late radiation damage in normal tissues
Khan AA, Paget JT, McLaughlin M et al.
Science Translational Medicine (2018) Online 24 January, Research Article.

180123
Partnerships for child health: capitalising on links between the sustainable development goals
Blomstedt Y, Bhutta ZA, Dahlstrand  J, Friberg P,  Gostin LO, Nilsson M, Sewankambo NK, Tomson G, Alfvén T.
BMJ (2018) Online 23 January. Analysis.

180117
Midbrain circuits that set locomotor speed and gait selection
Caggiano V, Leiras R, Goñi-Erro H, Masini D, Bellardita C, Bouvier J, Caldeira V, Fisone G, Kiehn O
Nature (2018) Online 17 January. Article.
På KI Nyheter: ”Startceller” i hjärnan styr om vi ska springa eller gå

180116
Risk for Arterial and Venous Thrombosis in Patients With Myeloproliferative Neoplasms: A Population-Based Cohort Study
Hultcrantz M,  Björkholm M, MD, Dickman PW, Landgren O, Derolf ÅR, Kristinsson SY, Andersson TML
Annals of Internal Medicine (2018) Online 16 January. Original Research.

180116
Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation
Emgård J, Kammoun H, García-Cassani B, Chesné J, Parigi SM, Jacob J-M, Cheng H-W, Evren E, Das S, Czarnewski P, Sleiers N, Melo-Gonzalez F, Kvedaraite E, Svensson M, Scandella E, Hepworth MR, Huber S, Ludewig B, Peduto L, Villablanca EJ, Veiga-Fernandes H, Pereira JP, Flavell RA, Willinger T.
Immunity (2018) Online 16 January. Article.
På KI Nyheter: Oxysteroler leder tarmens immunceller och är inblandade i inflammatorisk tarmsjukdom

180115
Conserved properties of dentate gyrus neurogenesis across postnatal development revealed by single-cell RNA sequencing' has been scheduled
Hochgerner H, Zeisel A, Lönnerberg P, Linnarsson S
Nature Neuroscience (2018) 15 January. Resource.

180103
Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells
Carrelha J, Meng Y, Kettyle LM, Luis TC, Norfo R, Alcolea V, Grasso F, Gambardella A, Grover A, Högstrand K, Lord AM, Sanjuan-Pla A, Woll PS, Nerlov C, Jacobsen SEW
Nature (2018) Online 3 January. Letter.

180101
An OPR 3-independent pathway uses 4,5-didehydrojasmonate for jasmonate synthesis
Chini A , Monte I , Zamarreño AM, Hamberg M, Lassueur S, Reymond P , Weiss S, Stintzi A, Schaller A,  Porzel A, García-Mina JM,  Solano R.
Nature Chemical Biology(2018) Online 1 January, Article.

180101
Multi-trait analysis of genome-wide association summary statistics using
Turley P, Walters RK,  Maghzian O et al.
Nature Genetics (2018) Online 1 January, Article.

171222
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
Demenais F, Margaritte-Jeannin P,  Barnes KC et al.
Nature Genetics (2017) Online 22 December. Article.

171221
Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation
Marty FM, Ljungman P, Chemaly RF et al.
NEJM (2017) Online 21 December. Original Article.

171221
Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner
Thion MS, Low D, Silvin A et al.
Cell (2017) Online 21 December. Article.

171215
Prostate Cancer Death After Radiotherapy or Radical Prostatectomy: A Nationwide Population-based Observational Study
Robinson D, Garmo H, Lissbrant IF, Widmark A, Pettersson A, Gunnlaugsson A, Adolfsson J, Bratt O, Nilsson P, Stattin P
European Urology (2017) Online 15 December. Article in Press.

171214
Our Gut Microbiome: The Evolving Inner Self
Kundu P, Blacher E, Elinav E, Pettersson S
Cell (2017) Online 14 December. Review.

171213
Association Between Methylphenidate and Amphetamine Use in Pregnancy and Risk of Congenital MalformationsA Cohort Study From the International Pregnancy Safety Study Consortium
Huybrechts KF, Bröms G, Brix Christensen L et al.
JAMA Psychiatry (2017) Online 13 December. Original Investigation.

171211
Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials
Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
The Lancet Oncology (2017) Online 11 December. Article.
Kommentar: Neoadjuvant chemotherapy in breast cancer: more than just downsizing

171207
Modifiable pathways in Alzheimer’s disease: Mendelian randomisation analysis
Larsson SC, Traylor M, Malik R, Dichgans M, Burgess S, Markus HS; for the CoSTREAM Consortium, on behalf of the International Genomics of Alzheimer’s Project.
BMJ (2017) Online 7 December. Research.
På KI Nyheter: Nya belägg för att lång utbildning minskar risken för alzheimer

171206
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4
Skrott Z, Mistrik M, Kaae Andersen K et al.
Nature (2017) Online 6 December. Article.
På KI Nyheter: Antabus dödar cancerceller

171204
An interactive framework for whole-brain maps at cellular resolution
Fürth D, Vaissière T, Tzortzi O, Xuan Y, Märtin A, Lazaridis I, Spigolon G, Fisone G, Tomer R, Deisseroth K, Carlén M, Miller CA, Rumbaugh G, Meletis K
Nature Neuroscience (2017) Online 4 December. Technical Report.

171129
Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia
Jansen WJ et al
JAMA Psychiatry (2017) Online 29 November. Original Investigation

171125
Pembrolizumab is effective for drug-resistant gestational trophoblastic neoplasia
Ghorani E, Kaur B, Fisher RA, Short D, Joneborg U, Carlson JW, Akarca A, Marafioti T, Quezada SA, Sarwar N, Seckl MJ
The Lancet (2017) Online 25 November. Article.

171113
An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression
Palazon A, Tyrakis PA, Macias D, Velica P, Rundqvist H, Fitzpatrick S, Vojnovic N, Phan AT, Loman N, Hedenfalk I, Hatschek T, Lövrot J, Foukakis T, Goldrath AW, Bergh J, Johnson RS
Cancer Cell (2017) Online 13 November. Article.
På KI Nyheter: Svårare för T-celler att bekämpa cancer om VEGF-A saknas

171109
20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years
Pan H, Gray R, Braybrooke J, Davies C, Taylor C, McGale P, Peto R, Pritchard KI, Bergh J, Dowsett M, Hayes. DF
NEJM (2017) Online 9 November. Original Article
På KI Nyheter: Oväntat långvarig risk för återfall i bröstcancer

171103
Fractional exhaled nitric oxide as a predictor of response to inhaled corticosteroids in patients with non-specific respiratory symptoms and insignificant bronchodilator reversibility: a randomised controlled trial
Price D, Buhl R, Chan A, Freeman D et al.
The Lancet Respiratory Medicine (2017) Online 3 November. Article in press.

171101
Incidence and Treatment of Patients Diagnosed With Inflammatory Bowel Diseases at 60 Years or Older in Sweden
Everhov ÅH, Halfvarson J, Myrelid P, Sachs MC, Nordenvall C, Söderling J, Ekbom A, Neovius M, Ludvigsson JF, Askling J, Olén O
Gastroenterology (2017) Online 1 November. Article in Press.
På KI Nyheter: Äldre tarmsjuka får äldre mediciner

171030
24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial
Soininen H, Solomon A, Jelle Visser P, Hendrix SB, Blennow K, Kivipelto M, Hartmann T on behalf of the LipiDiDiet clinical study group.
Lancet Neurology (2017) Online 30 October. Article.

171030
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
Ferreira MA, Vonk JM, Baurecht H et al.
Nature Genetics (2017) Online 30 October. Letter.
På KI Nyheter: Många gemensamma gener bakom astma, hösnuva och eksem

171027
What constitutes the prefrontal cortex?
Marie Carlén
Science (2017) online 27 October. Review.

171025
Prevalence of cerebral palsy in Uganda: a population-based study
Kakooza-Mwesige A, Andrews C, Peterson S, Wabwire Mangen F, Eliasson AC, Forssberg H
Lancet Global Health (2017) Online 25 October. Article.
På KI Nyheter: Stor kartläggning av cerebral pares i Uganda minskar kunskapsluckor

171025
Less dementia with oral anticoagulation in atrial fibrillation
Friberg L, Rosenqvist M
European Heart Journal (2017) Online 25 October. Article.
På KI Nyheter: Blodförtunnande läkemedel kopplas till minskad demensrisk vid förmaksflimmer

171023
Stable high-sensitivity cardiac troponin T levels and outcomes in patients with chest pain
Roos A, Bandstein N, Lundbäck M, Hammarsten O, Ljung R, Holzmann MJ
JACC (2017) Online 23 October. Article
På KI Nyheter: Troponin är förknippat med förhöjd risk att dö

171023
Deciphering lipid structures based on platform-independent decision rules
Hartler J, Triebl A, Ziegl A et al
Nature Methods (2017) Online 23 October. Brief Communication.

171017
Blood Transfusions From Previously Pregnant Women and MortalityInterpreting the Evidence
Cable RG, Edgren G
JAMA (2017) Online 17 October. Editorial.

171011
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System
Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundström E, Pachnis V, Marklund U
Gaestroentology (2017) Online 11 October. Article in Press.

171009
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia
Li Z, Chen J, Yu H et al
Nature Genetics (2017) Online 9 Otctober. Article.

171006
The promise of spatial transcriptomics for neuroscience in the era of molecular cell typing
Lein E, Borm LE, Linnarsson S
Science (2017) Online 6 October. Review.

171005
Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease
Eikelboom JW, Connolly SJ, Bosch J et al.
NEJM (2017) Online 5 October. Original Article.

171002
Risk of Cardiovascular Ischemic Events After Surgical Castration and Gonadotropin-Releasing Hormone Agonist Therapy for Prostate Cancer: A Nationwide Cohort Study
Chen DY,  See LC,  Liu JR,  Chuang CK, Pang ST, Hsieh IC, Wen MS, Chen TH, Lin YC, Liaw CC, Hsu CL, Chang JWC, Kuo CF, Huang  WK
JCO (2017) Online 2 October. Original Report.

170926
The Heritability of Autism Spectrum Disorder
Sandin S, Lichtenstein P, Kuja-Halkola R, Hultman C, Larsson H, Reichenberg A
JAMA (2017) Online 26 September. Research Letter.

170921
Bivalirudin versus Heparin Monotherapy in Myocardial Infarction
Erlinge D, Omerovic E, Fröbert O et al.
NEJM (2017) Online 21 September. Original Article.

170920
Childhood onset inflammatory bowel disease and risk of cancer: a Swedish nationwide cohort study 1964-2014
Olén O, Askling J, Sachs MC, Frumento P, Neovius M, Smedby KE, Ekbom A, Malmborg P, Ludvigsson JF
BMJ (2017) Online 20 September. Research.
På KI Nyheter: Inflammatorisk tarmsjukdom i barndomen kopplat till ökad cancerrisk

170914
Patent Foramen Ovale Closure or Antiplatelet Therapy for Cryptogenic Stroke
Søndergaard L, Kasner SE, Rhodes JF, Andersen G, Iversen HK, Nielsen-Kudsk JE, Settergren M, Sjöstrand C, Roine RO, Hildick-Smith D, Spence JD,  Thomassen L, for the Gore REDUCE Clinical Study Investigators
NEJM (2017) Online 14 September. Original Article. 

170913
Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial
Holman RR, Coleman RL, Chan JCN et al
Lancet Diabetes & Endocrinology (2017) Online 13 September. Article.

170912
Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation
Riffelmacher T, Clarke A, Richter FC, Stranks A, Pandey S, Danielli S, Hublitz P, Yu Z, Johnson E, Schwerd T, McCullagh J, Uhlig H, Jacobsen SEW, Simon AK.
Immunity (2017) Online 12 September. Article.

170912
Association Between Laparoscopic Antireflux Surgery and Recurrence of Gastroesophageal Reflux
Maret-Ouda J, Wahlin K, El-Serag HB, Lagergren J
JAMA (2017) Online 12 September. Original Investigation.
På KI Nyheter: Unga män som opereras mot reflux får sällan återfall

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