Nicholson Lecture 2018

Published 2018-10-30 11:58. Updated 2018-10-31 14:52
Elaine Fuchs
Photo: Erik Cronberg 

This year’s Nicholson lecturer from The Rockefeller University was Dr. Elaine Fuchs. On 24 October she held a lecture in Nobel Forum with the title Stem Cells: Coping with Stress. Dr. Elaine Fuchs has a long-standing interest in how stem cells form, maintain and repair tissues, focusing on the skin that harbors a large reservoir of stem cells in the adult body.

Professor Ole Petter Ottersen, President at Karolinska Institutet, opened the event with a warm welcome to Dr. Elaine Fuchs and the audience for the 14th lecture in the series, a lecture series which take place annually at KI and The Rockefeller University. Dr. Maria Kasper, Senior researcher at the Department of Biosciences and Nutrition then introduced Dr. Elaine Fuchs and her research.

Elaine Fuchs seeks to discover signals that for example can instruct skin stem cells to make new hair or repair epidermal injuries. She tackles these questions preferentially in mouse models using a combination of modern techniques, including live-cell imaging, cell biology, high-throughput genomics and functional approaches to identify regulatory pathways that dictate stem cell behavior such as self-renewal, differentiation and their aberrant roles in aging and cancer. Lately, her team has investigated how skin stem cells establish unique chromatin landscapes and programs of gene expression, and how this changes depend on their local microenvironment. The  global aim of Dr. Fuchs and her team is that the new findings will accelerate the development of therapeutics to enhance tissue regeneration.

The lecture attracted a large audience and ended with questions from the spectators. The lecture was also taped and can  be found on YouTube and on the website on the collaboration between KI and The Rockefeller University. Here you can also watch previous years' lectures.

The Nicholson Lectures is part of a larger collaboration between KI and The Rockefeller University which also include post doc exchange and short term exchange for researchers and faculty. More information at www.ki.se/rockefeller

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