Theme Center for Inflammatory Diseases

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Chronic inflammatory conditions, including rheumatic, neuroinflammatory, dermatological, intestinal and pulmonal diseases, are common chronic and severe diseases. However, there are great potentials to fundamentally change therapy and initiate prevention.

Swedish, and KI research has unique opportunities to contribute to such change from combining genetic epidemiology based on unique registers, with basic immunology, and with clinical immunology, clinical trials and clinical implementation.

The aims are:

  • To obtain a new understanding of mechanisms that cause major inflammatory diseases that are today defined by clinical criteria rather than from their different molecular origins.
  • To use this understanding to develop new means of prevention and therapy that can interfere with disease-inducing reactions before the inflammation has caused destruction and permanent disability.
  • To establish a new infrastructure for translational research concerning inflammatory diseases, which goes beyond existing programs at KI, by combining knowledge and international collaborations that are today utilized mainly in separate disease-specific networks. This new structure will enable young scientists to acquire broad skills in translational research as well as access to the best international networks in our field.



Professor, senior

Lars Klareskog

Organizational unit: group L Klareskog



Rikard Holmdahl

Phone: +46-(0)8-524 846 07
Organizational unit: Holmdahl

Group leaders

Lars AlfredssonInstitute of Environmental Medicine

Anders EkbomDepartment of Medicine, Solna

Johan GrunewaldDepartment of Medicine, Solna

Jesper Z HaeggströmDepartment of Medical Biochemistry and Biophysics

Marianne van HageDepartment of Medicine, Solna

Lennart HammarströmDepartment of Laboratory Medicine

Göran K HanssonDepartment of Medicine, Solna

Jan HillertDepartment of Clinical Neuroscience

Ingrid LundbergDepartment of Medicine, Solna

Tomas OlssonDepartment of Medicine, Solna

Sven PetterssonDepartment of Microbiology, Tumor and Cell Biology

Mona StåhleDepartment of Medicine, Solna

Marie Wahren-HerleniusDepartment of Medicine, Solna