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Intervention | Research at the EPiCSS group

The research in the EPiCSS group is broadly focused on interventions to reduce substance use, including alcohol, cannabis and other illicit drugs. Interventions studied include physical activity, internet-based treatment, and brief interventions in primary and specialist healthcare.

The goal is to broaden the array of effective treatments, increase help-seeking, and ultimately reduce substance use. Another aim is to identify factors that increase the risk of substance use, and factors associated with successful treatment outcomes.

Research projects

Evidence-based interventions for alcohol use disorders

Contact: Sven Andreasson, Anna-Karin Danielsson

There is an underuse of evidence-based interventions, including screening and brief intervention as well as treatment for alcohol use disorders. The overall aim with this project is to study innovative approaches to improve measurement of alcohol consumption and whether new technology can improve outcomes of treatment of alcohol use disorders.


Effect of Screening and Advising on Alcohol Habits in Sweden: A Repeated Population Survey Following Nationwide Implementation of Screening and Brief Intervention.
Lundin A, Danielsson AK, Hallgren M, Torgén M
Alcohol Alcohol. 2017 Mar;52(2):190-196

Preferences regarding treatment for alcohol problems.
Andréasson S, Danielsson AK, Wallhed-Finn S
Alcohol Alcohol. ;48(6):694-9

Alcohol consumption, dependence, and treatment barriers: perceptions among nontreatment seekers with alcohol dependence.
Wallhed Finn S, Bakshi AS, Andréasson S
Subst Use Misuse 2014 May;49(6):762-9

Web-Based Self-Help for Problematic Alcohol Use: a Large Naturalistic Study.
Johansson M, Sinadinovic K, Hammarberg A, Sundström C, Hermansson U, Andreasson S, et al
Int J Behav Med 2017 10;24(5):749-759

Rethinking alcohol interventions in health care: a thematic meeting of the International Network on Brief Interventions for Alcohol & Other Drugs (INEBRIA).
Glass JE, Andréasson S, Bradley KA, Finn SW, Williams EC, Bakshi AS, et al
Addict Sci Clin Pract 2017 05;12(1):14

Treatment for Alcohol Dependence in Primary Care Compared to Outpatient Specialist Treatment-A Randomized Controlled Trial.
Wallhed Finn S, Hammarberg A, Andreasson S
Alcohol Alcohol. 2018 Jul;53(4):376-385

Mindfulness and maternal depression/anxiety

Contact: Maria Niemi

Mindfulness based interventions have been included in the Swedish national guidelines for depression and anxiety management, and are increasingly being used in health-care. A novel mindfulness parental programme has in our pilot trial shown good effects on reducing stress and depression in participating parents from pre- to post-intervention.

The aim of this study is to examine whether this parental programme is more effective than usual maternal care in preventing adverse psychosocial and health consequences for the infant.

Altogether 213 participants, selected on basis of increased risk for perinatal stress or depression and/or childhood adversity, have been randomized to an intervention or control group.

Maternal physiological, biological and psychological outcome measures have already been gathered at baseline, post-intervention, and 3, 9 and 12 months post-intervention.

Exercise and mental health

Contact: Mats Hallgren

Two ongoing projects in the EPiCSS research group focus on links between physical activity, wellbeing and mental health. The first project 'FitForChange' is a randomized controlled trial (RCT) investigating effects of a 12-week exercise programme on alcohol consumption (primary outcome) and health-related variables (stress, depression/anxiety, sleep quality, etc) in alcohol dependent adults. This study is run at 'Riddargatan1', an outpatient clinic located in central Stockholm.

The second project, FitForAge, also an RCT, aims to better understand the effects of yoga-based exercise on subjective wellbeing (primary outcome), health related outcomes in older adults (65-85 years). In addition to self-report measures of health, both studies include biological markers to assess intervention effects; e.g. cortisol, inflammatory markers.

Study protocol (FitForAge)

Effects of yoga on wellbeing and healthy ageing: a randomized controlled trial (FitForAge) (pdf)


Physical activity as treatment for alcohol use disorders (FitForChange): study protocol for a randomized controlled trial.
Hallgren M, Andersson V, Ekblom Ö, Andréasson S
Trials 2018 Feb;19(1):106

More Reasons to Move: Exercise in the Treatment of Alcohol Use Disorders.
Hallgren M, Vancampfort D, Schuch F, Lundin A, Stubbs B
Front Psychiatry 2017 ;8():160

Exercise as treatment for alcohol use disorders: systematic review and meta-analysis.
Hallgren M, Vancampfort D, Giesen ES, Lundin A, Stubbs B
Br J Sports Med 2017 Jul;51(14):1058-1064