Epidemiology and Public Health Intervention Research (EPHIR)

The research group aims at conducting high quality research within the area of public health epidemiology, especially applied to the evaluation of public health interventions.

Research areas

Research projects encompass descriptive, analytical as well as experimental studies in both community and institutional settings, with particular focus on social, behavioral and lifestyle factors of importance for human health during the whole life span. Also, studies rest on a variety of data sources, involving ad-hoc surveys, population-based registers, as well as biologic samples, particularly molecular genetics.


There are ongoing national collaborations within KI and external with Occupational health, Uppsala, Center for Social research on Alcohol and Drugs and Centre for Equity Studies (CHESS), Stockholm University, and many other academic institutions. An important partner is the Centre for Epidemiology and Community Health of Stockholm County Health Care District (CES), where several of the group researchers have part-time commitments.
Internationally the group holds collaborations with Helsinki University, Oxford Brookes and Sheffield University (UK) and Avogadro University (IT).
The group is among the promoters of the European Society of Prevention Research (EUSPR) and of the SPAN (Science for Prevention Academic Network), funded by the Erasmus Lifelong Learning Program.


The group are actively involved in education at all levels and includes the responsible for the undergraduate education (GUA) at the Department of Public Health Sciences and the director of studies for the Public Health Epidemiology track in Public Health. 


Currently the group has grants from Vårdal, FAS/Forte, HjärtLungfonden, Länsförsäkringar, FORMAS, Folkhälsoinstitutet, European Commission and VR.

Ongoing research projects

  • KUPOL - The KUPOL Study on mental health in adolescence.
  • PART - Study on risk and protective factors for mental health. 
  • REGASSA - a randomized controlled trial of internet-based cognitive behavioral therapy, physical activity and treatment as usual in mild to moderate depression.

Doctoral theses

Title Author
Exercise as treatment for depression (2016) Björg Helgadottir
Tobacco use and dependence: does it originate in utero? (2014) Mina Rydell
Social Environment and Genetics as Determinants of Depression Occurrence and Its Chronicity: A Longitudinal Survey (2013) Carlos Andrés Fandiño-Losada
Triggers of Sick Leave: Epidemiological Studies of Work-Related Factors (2011) Hanna Hultin

Scientific publications

Path analysis of the chronicity of depression using the comprehensive developmental model framework.
Fandiño-Losada A, Bangdiwala S, Lavebratt C, Forsell Y
Nord J Psychiatry 2016 Jul;70(5):380-91

The validity of the symptom checklist depression and anxiety subscales: A general population study in Sweden.
Lundin A, Hallgren M, Forsell Y
J Affect Disord 2015 Sep;183():247-52

Anti-Social Behaviors Associated with Anabolic-Androgenic Steroid Use among Male Adolescents.
Hallgren M, Pope H, Kanayama G, Hudson J, Lundin A, Källmén H
Eur Addict Res 2015 ;21(6):321-6

Physical exercise and internet-based cognitive-behavioural therapy in the treatment of depression: randomised controlled trial.
Hallgren M, Kraepelien M, Öjehagen A, Lindefors N, Zeebari Z, Kaldo V, et al
Br J Psychiatry 2015 Sep;207(3):227-34

Evaluation of a brief counseling for tobacco cessation in dental clinics among Swedish smokers and snus users. A cluster randomized controlled trial (the FRITT study).
Virtanen S, Zeebari Z, Rohyo I, Galanti M
Prev Med 2015 Jan;70():26-32

Increased screening of alcohol habits among patients with depression is needed.
Hallgren M, Åhlin J, Forsell Y, Öjehagen A
Scand J Public Health 2014 Nov;42(7):658-9

Social factors in childhood and risk of depressive symptoms among adolescents--a longitudinal study in Stockholm, Sweden.
Wirback T, Möller J, Larsson J, Galanti M, Engström K
Int J Equity Health 2014 Nov;13():96

Medication and fall injury in the elderly population; do individual demographics, health status and lifestyle matter?
Helgadóttir B, Laflamme L, Monárrez-Espino J, Möller J
BMC Geriatr 2014 Aug;14():92

Systematic review of the effect of pictorial warnings on cigarette packages in smoking behavior.
Monárrez-Espino J, Liu B, Greiner F, Bremberg S, Galanti R
Am J Public Health 2014 Oct;104(10):e11-30

School policies for preventing smoking among young people.
Coppo A, Galanti M, Giordano L, Buscemi D, Bremberg S, Faggiano F
Cochrane Database Syst Rev 2014 Oct;(10):CD009990

The use of alcohol use disorders identification test (AUDIT) in detecting alcohol use disorder and risk drinking in the general population: validation of AUDIT using schedules for clinical assessment in neuropsychiatry.
Lundin A, Hallgren M, Balliu N, Forsell Y
Alcohol. Clin. Exp. Res. 2015 Jan;39(1):158-65

An evaluation of long-term changes in alcohol use and alcohol problems among clients of the Swedish National Alcohol Helpline.
Heinemans N, Toftgård M, Damström-Thakker K, Galanti M
Subst Abuse Treat Prev Policy 2014 Jun;9():22

Impact of expectations on the effects of exercise on psychological distress.
Helgadóttir B, Ekblom , Forsell Y
Am J Health Behav 2014 Sep;38(5):650-6

Use of a water pipe is not an alternative to other tobacco or substance use among adolescents: results from a national survey in Sweden.
Galanti M, Al-Adhami M
Nicotine Tob. Res. 2015 Jan;17(1):74-80

The risk of fall injury in relation to commonly prescribed medications among older people--a Swedish case-control study.
Kuschel B, Laflamme L, Möller J
Eur J Public Health 2015 Jun;25(3):527-32

Youth alcohol polarization effects in regional but not national data.
Hallgren M
Addiction 2014 Aug;109(8):1384-5

The psychometric properties of the AUDIT: a survey from a random sample of elderly Swedish adults.
Källmén H, Wennberg P, Ramstedt M, Hallgren M
BMC Public Health 2014 Jul;14():672

Yoga as an adjunct treatment for alcohol dependence: a pilot study.
Hallgren M, Romberg K, Bakshi A, Andréasson S
Complement Ther Med 2014 Jun;22(3):441-5

CYP2D6-inhibiting drugs and the increased risk of fall-related injuries due to newly initiated opioid treatment--a Swedish, register-based case-crossover study.
Möller J, Laflamme L, Söderberg Löfdal K
Basic Clin. Pharmacol. Toxicol. 2015 Feb;116(2):134-9

[Use of immunological adsorption in heterogeneous immunoenzyme analysis in determining antibodies to the protective determinants of Bacillus anthracis].
Abalakin V
Zh. Mikrobiol. Epidemiol. Immunobiol. 1987 Nov;(11):90-4

"Unplugged," a European school-based program for substance use prevention among adolescents: overview of results from the EU-Dap trial.
Vigna-Taglianti F, Galanti M, Burkhart G, Caria M, Vadrucci S, Faggiano F, et al
New Dir Youth Dev 2014 ;2014(141):67-82, 11-2

Number of medications and road traffic crashes in senior Swedish drivers: a population-based matched case-control study.
Monárrez-Espino J, Laflamme L, Elling B, Möller J
Inj. Prev. 2014 Apr;20(2):81-7

An association between initiation of selective serotonin reuptake inhibitors and suicide - a nationwide register-based case-crossover study.
Björkenstam C, Möller J, Ringbäck G, Salmi P, Hallqvist J, Ljung R
PLoS ONE 2013 ;8(9):e73973

Analgesics and road traffic crashes in senior drivers: an epidemiological review and explorative meta-analysis on opioids.
Monárrez-Espino J, Möller J, Berg H, Kalani M, Laflamme L
Accid Anal Prev 2013 Aug;57():157-64

Lack of adjustment latitude at work as a trigger of taking sick leave-a Swedish case-crossover study.
Hultin H, Hallqvist J, Alexanderson K, Johansson G, Lindholm C, Lundberg I, et al
PLoS ONE 2013 ;8(4):e61830

Demands, skill discretion, decision authority and social climate at work as determinants of major depression in a 3-year follow-up study.
Fandiño-Losada A, Forsell Y, Lundberg I
Int Arch Occup Environ Health 2013 Jul;86(5):591-605

Working conditions, serotonin transporter gene polymorphism (5-HTTLPR) and anxiety disorders: a prospective cohort study.
Liu B, Lavebratt C, Nordqvist T, Fandiño-Losada A, Theorell T, Forsell Y, et al
J Affect Disord 2013 Nov;151(2):652-9

Stress as a Trigger for Relapses in IBD: A Case-Crossover Study.
Jaghult S, Saboonchi F, Moller J, Johansson U, Wredling R, Kapraali M
Gastroenterology Res 2013 Feb;6(1):10-16

Job insecurity and prognosis after myocardial infarction: the SHEEP Study.
László K, Engström K, Hallqvist J, Ahlbom A, Janszky I
Int. J. Cardiol. 2013 Sep;167(6):2824-30

Unlicensed driving and other related health risk behaviors: a study of Montana high school students.
Hanna C, Laflamme L, Elling B, Möller J
Accid Anal Prev 2013 May;54():26-31

Newly initiated opioid treatment and the risk of fall-related injuries. A nationwide, register-based, case-crossover study in Sweden.
Söderberg K, Laflamme L, Möller J
CNS Drugs 2013 Feb;27(2):155-61

The triggering effect of alcohol and illicit drugs on violent crime in a remand prison population: a case crossover study.
Lundholm L, Haggård U, Möller J, Hallqvist J, Thiblin I
Drug Alcohol Depend 2013 Apr;129(1-2):110-5

Influence of serotonin transporter promoter variation on the effects of separation from parent/partner on depression.
Fandiño-Losada A, Wei Y, Aberg E, Sjöholm L, Lavebratt C, Forsell Y
J Affect Disord 2013 Jan;144(3):216-24

The functional Val158Met polymorphism in catechol-O-methyltransferase (COMT) is associated with depression and motivation in men from a Swedish population-based study.
Åberg E, Fandiño-Losada A, Sjöholm L, Forsell Y, Lavebratt C
J Affect Disord 2011 Mar;129(1-3):158-66

Group members

Aysha AlmasGraduate Student


Melody AlmrothGraduate Student, Research officer


Filip AnderssonAssociated


Elin ArnöResearch coordinator


Pimchanok BunnakResearch officer


Hua ChenGraduate Student


Louise EhrenbergResearch assistant


Karin EngströmAssociated


Yvonne ForsellAdjunct professor


Rosaria GalantiAdjunct professor


Johanna HoffstenResearch assistant


Hanna HultinAssociated


Fouad JabriGraduate Student


Imre JanszkyAssociated


Charisse JohnsonGraduate Student


Yajun LiangAssistant professor


Krisztina LászlóAssistant professor


Anna MånsdotterAssociated


Jette MöllerAssociate professor


08-524 801 22

Carla NooijenAssociated


Malin PetterssonAssociated


Elena RaffettiPhD student, Graduate Student


Arun John Saldanha ShetGraduate Student


Eleonor SäfstenAssociated


Veronika TiradoEducational assistant


Dang WeiGraduate Student


Therese WirbackPhD student, Graduate Student


Diego Yacaman MendezResearch assistant


Josefine ÖsthResearch assistant



Contact us

Adjunct professor

Yvonne Forsell

Organizational unit: Public Health Epidemiology
E-mail: Yvonne.Forsell@ki.se

Intervention researchSocial Medicine