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About me

We are a multidisciplinary research team with two registered graduate students, senior researchers and many young people interested in pancreatology. National cooperation network for proteomics and RCTs, and internationally in the ESPAC's. We participate actively in international meetings such as the Europe


Teaching interest
Pancreatology, Pancreatic surgery , Pancreatic cancer, and bile duct diseases.

Research description

Research interest
Pancreatology, Pancreatic surgery , Pancreatic cancer.


Development and Feasibility of an Interactive Smartphone App for Early Assessment and Management of Symptoms Following Pancreaticoduodenectomy
Gustavell T, Langius-eklöf A, Wengström Y, Segersvärd R, Sundberg K
Cancer nursing 2018;():-

European evidence-based guidelines on pancreatic cystic neoplasms
European Study Grp Cystic Tum, Del Chiaro M, Besselink Mg, Scholten L, Bruno Mj, Cahen Dl, et al
GUT 2018;67(5):789-804

Pancreatectomies for pancreatic neoplasms in pediatric and adolescent age: A single institution experience
Scandavini C, Valente R, Rangelova E, Segersvärd R, Arnelo U, Permert J, et al
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2018;18(2):204-207

A Preliminary Report: Radical Surgery and Stem Cell Transplantation for the Treatment of Patients With Pancreatic Cancer
Omazic B, Ayoglu B, Löhr M, Segersvärd R, Verbeke C, Magalhaes I, et al
Journal of immunotherapy (Hagerstown, Md. : 1997) 2017;():-

Survival Analysis and Risk for Progression of Intraductal Papillary Mucinous Neoplasia of the Pancreas (IPMN) Under Surveillance: A Single-Institution Experience
Del Chiaro M, Ateeb Z, Hansson Mr, Rangelova E, Segersvärd R, Kartalis N, et al
Annals of surgical oncology 2017;24(4):1120-1126

Symptoms and self-care following pancreaticoduodenectomy: Perspectives from patients and healthcare professionals - Foundation for an interactive ICT application
Gustavell T, Sundberg K, Frank C, Wengström Y, Browall M, Segersvärd R, et al
European journal of oncology nursing : the official journal of European Oncology Nursing Society 2017;26():36-41

Are there still indications for total pancreatectomy?
Del Chiaro M, Rangelova E, Segersvärd R, Arnelo U
Updates in surgery 2016;68(3):257-263

Cattell-Braasch maneuver combined with local hypothermia during superior mesenteric artery resection in pancreatectomy
Westermark S, Rangelova E, Ansorge C, Lundell L, Segersvärd R, Del Chiaro M
Langenbeck's archives of surgery 2016;401(8):1241-1247

Expansion of Tumor-reactive T Cells From Patients With Pancreatic Cancer
Meng Q, Liu Z, Rangelova E, Poiret T, Ambati A, Rane L, et al
Journal of immunotherapy (Hagerstown, Md. : 1997) 2016;39(2):81-9

Leakage of albumin in major abdominal surgery
Norberg Å, Rooyackers O, Segersvärd R, Wernerman J
Critical care (London, England) 2016;20(1):113-

Multidetector CT of pancreatic ductal adenocarcinoma: Effect of tube voltage and iodine load on tumour conspicuity and image quality
Loizou L, Albiin N, Leidner B, Axelsson E, Fischer Ma, Grigoriadis A, et al
European radiology 2016;26(11):4021-4029

Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas)
Jais B, Rebours V, Malleo G, Salvia R, Fontana M, Maggino L, et al
Gut 2016;65(2):305-12

Albumin Kinetics in Patients Undergoing Major Abdominal Surgery
Norberg Å, Rooyackers O, Segersvärd R, Wernerman J
PloS one 2015;10(8):e0136371-

Association between pancreatic intraductal papillary mucinous neoplasms and extrapancreatic malignancies
Marchegiani G, Malleo G, D'haese Jg, Wenzel P, Keskin M, Pugliese L, et al
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2015;13(6):1162-9

Cattell-Braasch Maneuver Combined with Artery-First Approach for Superior Mesenteric-Portal Vein Resection During Pancreatectomy
Del Chiaro M, Segersvärd R, Rangelova E, Coppola A, Scandavini Cm, Ansorge C, et al
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2015;19(12):2264-8

Outcome of probe-based confocal laser endomicroscopy (pCLE) during endoscopic retrograde cholangiopancreatography: A single-center prospective study in 45 patients
Lohr Jm, Lonnebro R, Stigliano S, Haas Sl, Swahn F, Enochsson L, et al

Pancreas-preserving duodenectomy is a safe alternative to high-risk pancreatoduodenectomy for premalignant duodenal lesions
Rangelova E, Blomberg J, Ansorge C, Lundell L, Segersvärd R, Del Chiaro M
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2015;19(3):492-7

Short-term Results of a Magnetic Resonance Imaging-Based Swedish Screening Program for Individuals at Risk for Pancreatic Cancer
Del Chiaro M, Verbeke Cs, Kartalis N, Pozzi Mucelli R, Gustafsson P, Hansson J, et al
JAMA surgery 2015;150(6):512-8

Variant Profiling of Candidate Genes in Pancreatic Ductal Adenocarcinoma
Huang J, Löhr Jm, Nilsson M, Segersvärd R, Matsson H, Verbeke C, et al
Clinical chemistry 2015;61(11):1408-16

Assessing surgical quality: comparison of general and procedure-specific morbidity estimation models for the risk adjustment of pancreaticoduodenectomy outcomes
Ansorge C, Lindström P, Strömmer L, Blomberg J, Lundell L, Andrén-sandberg A, et al
World journal of surgery 2014;38(9):2412-21

Comparison of preoperative conference-based diagnosis with histology of cystic tumors of the pancreas
Del Chiaro M, Segersvärd R, Pozzi Mucelli R, Rangelova E, Kartalis N, Ansorge C, et al
Annals of surgical oncology 2014;21(5):1539-44

Correlation between preoperative imaging and intraoperative risk assessment in the prediction of postoperative pancreatic fistula following pancreatoduodenectomy
Frozanpor F, Loizou L, Ansorge C, Lundell L, Albiin N, Segersvärd R
World journal of surgery 2014;38(9):2422-9

Diagnostic value of abdominal drainage in individual risk assessment of pancreatic fistula following pancreaticoduodenectomy
Ansorge C, Nordin Jz, Lundell L, Strömmer L, Rangelova E, Blomberg J, et al
The British journal of surgery 2014;101(2):100-8

Early detection and prevention of pancreatic cancer: is it really possible today?
Del Chiaro M, Segersvärd R, Lohr M, Verbeke C
World journal of gastroenterology 2014;20(34):12118-31

Innovations in pancreatic surgery
Hirota M, Sand J, Segersvärd R, Cirocchi R
BioMed research international 2014;2014():963416-

Is intraductal tubulopapillary neoplasia a new entity in the spectrum of familial pancreatic cancer syndrome?
Del Chiaro M, Mucelli Rp, Blomberg J, Segersvärd R, Verbeke C
Familial cancer 2014;13(2):227-9

Single-operator pancreatoscopy is helpful in the evaluation of suspected intraductal papillary mucinous neoplasms (IPMN)
Arnelo U, Siiki A, Swahn F, Segersvärd R, Enochsson L, Del Chiaro M, et al
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2014;14(6):510-4

The state of the art of robotic pancreatectomy
Del Chiaro M, Segersvärd R
BioMed research international 2014;2014():920492-

The use of LigaSure™ Does not Affect Histologic Margin Assessment in Pancreatoduodenectomy (PD) specimens
Del Chiaro M, Blomberg J, Segersvärd R, Rangelova E, Ansorge C, Verbeke C
JOP : Journal of the pancreas 2014;15(6):597-9

Computed tomography staging of pancreatic cancer: a validation study addressing interobserver agreement
Loizou L, Albiin N, Ansorge C, Andersson M, Segersvärd R, Leidner B, et al
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2013;13(6):570-5

Conservative treatment of chronic pancreatitis
Löhr Jm, Haas Sl, Lindgren F, Enochsson L, Hedström A, Swahn F, et al
Digestive diseases (Basel, Switzerland) 2013;31(1):43-50

Enucleation of branch duct-IPMN in a transplant patient
Del Chiaro M, Albiin N, Segersvärd R
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2013;13(3):312-3

European experts consensus statement on cystic tumours of the pancreas
European Study Group On Cystic Tumours Of The Pancreas, Del Chiaro M, Verbeke C, Salvia R, Klöppel G, Werner J, et al
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2013;45(9):703-11

Impact of body mass index for patients undergoing pancreaticoduodenectomy
Del Chiaro M, Rangelova E, Ansorge C, Blomberg J, Segersvärd R
World journal of gastrointestinal pathophysiology 2013;4(2):37-42

Portal venous system thrombosis after pancreatic resection
Ansari D, Ansorge C, Andrén-sandberg A, Ansari D, Segersvärd R
World journal of surgery 2013;37(1):179-84

Early intraperitoneal metabolic changes and protease activation as indicators of pancreatic fistula after pancreaticoduodenectomy
Ansorge C, Regner S, Segersvärd R, Strömmer L
The British journal of surgery 2012;99(1):104-11

Effect of adjuvant chemotherapy with fluorouracil plus folinic acid or gemcitabine vs observation on survival in patients with resected periampullary adenocarcinoma: the ESPAC-3 periampullary cancer randomized trial
European Study Group For Pancreatic Cancer, Neoptolemos Jp, Moore Mj, Cox Tf, Valle Jw, Palmer Dh, et al
JAMA 2012;308(2):147-56

Identification of serum biomarker signatures associated with pancreatic cancer
Wingren C, Sandström A, Segersvärd R, Carlsson A, Andersson R, Löhr M, et al
Cancer research 2012;72(10):2481-90

Management of alcohol use disorders in patients with chronic pancreatitis
Lang Mb, Segersvärd R, Grundsten M, Segerdahl M, Arnelo U, Permert J, et al
JOP : Journal of the pancreas 2012;13(6):654-9

Optimising diffusion-weighted MR imaging for demonstrating pancreatic cancer: a comparison of respiratory-triggered, free-breathing and breath-hold techniques
Kartalis N, Loizou L, Edsborg N, Segersvärd R, Albiin N
European radiology 2012;22(10):2186-92

Preoperative pancreas CT/MRI characteristics predict fistula rate after pancreaticoduodenectomy
Frozanpor F, Loizou L, Ansorge C, Segersvärd R, Lundell L, Albiin N
World journal of surgery 2012;36(8):1858-65

Serum proteome profiling of pancreatitis using recombinant antibody microarrays reveals disease-associated biomarker signatures
Sandström A, Andersson R, Segersvärd R, Löhr M, Borrebaeck Ca, Wingren C
Proteomics. Clinical applications 2012;6(9-10):486-96

Structured intraoperative assessment of pancreatic gland characteristics in predicting complications after pancreaticoduodenectomy
Ansorge C, Strömmer L, Andrén-sandberg Å, Lundell L, Herrington Mk, Segersvärd R
The British journal of surgery 2012;99(8):1076-82

The effect of prophylactic transpapillary pancreatic stent insertion on clinically significant leak rate following distal pancreatectomy: results of a prospective controlled clinical trial
Frozanpor F, Lundell L, Segersvärd R, Arnelo U
Annals of surgery 2012;255(6):1032-6

Validation of the Harmless Acute Pancreatitis Score in Predicting Nonsevere Course of Acute Pancreatitis
Oskarsson V, Mehrabi M, Orsini N, Hammarqvist F, Segersvard R, Andren-sandberg A, et al
PANCREATOLOGY 2011;11(5):464-8

Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid vs Gemcitabine Following Pancreatic Cancer Resection A Randomized Controlled Trial
European Study Grp Pancreatic Canc, Neoptolemos Jp, Stocken Dd, Bassi C, Ghaneh P, Cunningham D, et al

Clinical and Experimental Pancreatic Islet Transplantation to Striated Muscle Establishment of a Vascular System Similar to That in Native Islets
Christoffersson G, Henriksnas J, Johansson L, Rolny C, Ahlstrom H, Caballero-corbalan J, et al
DIABETES 2010;59(10):2569-78

Impact of pancreatic gland volume on fistula formation after pancreatic tail resection
Frozanpor F, Albiin N, Linder S, Segersvärd R, Lundell L, Arnelo U
JOP : Journal of the pancreas 2010;11(5):439-43

Pancreatic Cancer Cells Expressing Hypoxia-Inducible Factor-1 alpha Tend to Be Adjacent to Intratumoral Blood Vessels
Cheng Bq, Segersvard R, Permert J, Wang F

Distal Pancreatectomy: Surgery with An Unjustified Reputation
Frozanpor F, Arnelo U, Segersvard R, Linder S, Permert J, Lundell Lr
GASTROENTEROLOGY 2009;136(5):A897-A897

Obesity alters cytokine gene expression and promotes liver injury in rats with acute pancreatitis
Segersvaerd R, Tsai Ja, Herrington Mk, Wang F
OBESITY 2008;16(1):23-8

Hypoxia inducible factor-1 mediates effects of insulin on pancreatic cancer cells and disturbs host energy homeostasis
Wang F, Li Ss, Segersvard R, Strommer L, Sundqvist Kg, Holgersson J, et al

LY293111 improves efficacy of gemcitabine therapy on pancreatic cancer in a fluorescent orthotopic model in athymic mice
Hennig R, Ventura J, Segersvard R, Ward E, Ding Xz, Rao Sm, et al
NEOPLASIA 2005;7(4):417-25

mRNA for pancreatic uncoupling protein 2 increases in two models of acute experimental pancreatitis in rats and mice
Segersvard R, Rippe C, Duplantier M, Herrington Mk, Isaksson B, Adrian Te, et al
CELL AND TISSUE RESEARCH 2005;320(2):251-8

Impact of chronic and acute high-fat feeding on acute experimental pancreatitis complicated by endotoxinaemia
Segersvard R, Sylvan M, Lempinen M, Larsson J, Permert J

Obstructive jaundice results in increased liver expression of uncoupling protein 2 and intact skeletal muscle glucose metabolism in the rat
Isaksson B, Rippe C, Simonoska R, Holm Je, Glaumann H, Segersvard R, et al

Obesity increases the severity of acute experimental pancreatitis in the rat
Segersvard R, Sylvan M, Herrington M, Larsson J, Permert J

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