Ralf Segersvärd

About me
Publications
CV
Public outreach and news

About me

We are a multidisciplinary research team with two registered graduate
students, senior researchers and many young people interested in
pancreatology. National cooperation network for proteomics and RCTs, and
internationally in the ESPAC's. We participate actively in international
meetings such as the Europe
*Teaching interest*
Pancreatology, Pancreatic surgery , Pancreatic cancer, and bile duct
diseases.

Research

*Research interest*
Pancreatology, Pancreatic surgery , Pancreatic cancer.

Articles

Journal article: QUALITY OF LIFE RESEARCH. 2024;33(3):667-678

Differences in health-related quality of life between native and foreign-born gynaecological cancer patients in Sweden: a five-year cross-sectional study.

Karlsson Rosenblad A; Westman B; Bergkvist K; Segersvärd R; Roos N; Bergenmar M; Sharp L
Article: ANNALS OF SURGERY. 2021;273(3):579-586

Surgery Improves Survival After Neoadjuvant Therapy for Borderline and Locally Advanced Pancreatic Cancer: A Single Institution Experience.

Rangelova E; Wefer A; Persson S; Valente R; Tanaka K; Orsini N; Segersvärd R; Arnelo U; Del Chiaro M
Article: PLOS ONE. 2021;16(7):e0254673

Health care utilization at end of life among patients with lung or pancreatic cancer. Comparison between two Swedish cohorts.

Ullgren H; Fransson P; Olofsson A; Segersvärd R; Sharp L
Journal article: PANCREATOLOGY. 2020;20:s49-s50

Centralisation improves survival of pancreatic cancer by increased surgical indications and resection rates – a population-based study

Rangelova E; Ebrahim F; Sharp L; Henriksson R; Segersvärd R
Journal article: PANCREATOLOGY. 2020;20:s17-s18

ESPAC-4: A randomized controlled phase III trial of adjuvant gemcitabine (GEM) and capecitabine (CAP) versus gemcitabine in resected pancreatic ductal adenocarcinoma: five year follow up.

Neoptolemos J; Palmer D; Gahneh P; Valle J; Cunningham D; Wadsley J; Meyer T; Anthoney A; Glimelius B; Falk S; Segersvard R; Middleton G; Ross P; Wasan H; Mcdonald A; Crosby T; Psarelli E; Hammel P; Hackert T; Halloran C; Buchler M
Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2020;38(15_suppl):4516

ESPAC-4: A multicenter, international, open-label randomized controlled phase III trial of adjuvant combination chemotherapy of gemcitabine (GEM) and capecitabine (CAP) versus monotherapy gemcitabine in patients with resected pancreatic ductal adenocarcinoma: Five year follow-up.

Neoptolemos JP; Palmer DH; Ghaneh P; Valle JW; Cunningham D; Wadsley J; Meyer T; Anthoney A; Glimelius B; Falk S; Segersvard R; Middleton GW; Ross PJ; Wasan HS; McDonald A; Crosby TDL; Psarelli EE; Hammel P; Hackert T; Buchler MW
Article: ACTA ONCOLOGICA. 2019;58(9):1307-1314

Decreased symptom burden following surgery due to support from an interactive app for symptom management for patients with pancreatic and periampullary cancer.

Gustavell T; Sundberg K; Segersvärd R; Wengström Y; Langius-Eklöf A
Journal article: PANCREATOLOGY. 2019;19:s114-s115

Elevated Ca 19-9 predicts the presence of metastatic aortocaval lymph nodes and impaired survival in resected patients with borderline and locally advanced pancreatic cancer

Rangelova E; Tanaka K; Halimi A; Valente R; Arnelo U; Segersvärd R; Del Chiaro M
Journal article: PANCREATOLOGY. 2019;19:s14

A single-center experience with 312 venous resections with pancreatectomy: Only elevated Ca 19-9 indicates impaired survival

Rangelova E; Kivila R; Tanaka K; Valente R; Halimi A; Segersvärd R; Arnelo U; Del Chiaro M
Article: CANCER NURSING. 2019;42(3):E1-E10

Development and Feasibility of an Interactive Smartphone App for Early Assessment and Management of Symptoms Following Pancreaticoduodenectomy.

Gustavell T; Langius-Eklöf A; Wengström Y; Segersvärd R; Sundberg K
Article: HPB. 2019;21(2):219-225

Pancreatectomy with arterial resection is superior to palliation in patients with borderline resectable or locally advanced pancreatic cancer.

Del Chiaro M; Rangelova E; Halimi A; Ateeb Z; Scandavini C; Valente R; Segersvärd R; Arnelo U; Verbeke CS
Journal article: HPB. 2019;21:s696

First results from the Swedish National Pancreatic and Periampullary Cancer Registry

Tingstedt B; Jönsson C; Bratlie S-O; Öman M; Karlson BM; Ansorge C; Segersvärd R; Gasslander T
Journal article: HPB. 2019;21:s984

First results from the Swedish national pancreatic and periampullary cancer registry.

Tingstedt B; Jönsson C; Bratlie S-O; Öman M; Karlson BM; Ansorge C; Segersvärd R; Gasslander T
Article: HPB. 2019;21(1):34-42

First results from the Swedish National Pancreatic and Periampullary Cancer Registry.

Tingstedt B; Andersson B; Jönsson C; Formichov V; Bratlie S-O; Öhman M; Karlsson B-M; Ansorge C; Segersvärd R; Gasslander T
Article: PANCREATOLOGY. 2018;18(7):734-741

RCAN1 is a marker of oxidative stress, induced in acute pancreatitis.

Norberg KJ; Nania S; Li X; Gao H; Szatmary P; Segersvärd R; Haas S; Wagman A; Arnelo U; Sutton R; Heuchel RL; Löhr JM
Article: EUROPEAN JOURNAL OF RADIOLOGY. 2018;106:69-76

Radiological assessment of local resectability status in patients with pancreatic cancer: Interreader agreement and reader performance in two different classification systems.

Loizou L; Duran CV; Axelsson E; Andersson M; Keussen I; Strinnholm J; Bartholomä W; Del Chiaro M; Segersvärd R; Lundell L; Kartalis N
Journal article: PANCREATOLOGY. 2018;18(4):s6

Neo-adjuvant treatment for borderline and locally advanced pancreatic cancer: A single institution experience

Rangelova E; Wefer A; Persson S; Valente R; Segersvärd R; Arnelo U; Del Chiaro M
Article: GUT. 2018;67(5):789-804

European evidence-based guidelines on pancreatic cystic neoplasms.

European Study Group on Cystic Tumours of the Panc
Journal article: ANNALS OF PANCREATIC CANCER. 2018;1(4):ab089

AB089. P061. Pancreatectomies associated to vein resection: a large single institution experience

Kivila R; Valente R; Rangelova E; Halimi A; Ateeb Z; Scandavini C; Segersvard R; Arnelo U; Del Chiaro M
Journal article: ANNALS OF PANCREATIC CANCER. 2018;1(4):ab019

AB019. S019. Pancreatectomy plus arterial resection is superior to palliation in patients with locally advanced PDAC

Del Chiaro M; Rangelova E; Halimi A; Ateeb Z; Scandavini C; Valente R; Lundell L; Segersvard R; Arnelo U
Article: PANCREATOLOGY. 2018;18(2):204-207

Pancreatectomies for pancreatic neoplasms in pediatric and adolescent age: A single institution experience.

Scandavini C; Valente R; Rangelova E; Segersvärd R; Arnelo U; Permert J; Svensson P-J; Stenman J; Del Chiaro M
Article: JOURNAL OF IMMUNOTHERAPY. 2017;40(4):132-139

A Preliminary Report: Radical Surgery and Stem Cell Transplantation for the Treatment of Patients With Pancreatic Cancer.

Omazic B; Ayoglu B; Löhr M; Segersvärd R; Verbeke C; Magalhaes I; Potacova Z; Mattsson J; Terman A; Ghazi S; Albiin N; Kartalis N; Nilsson P; Poiret T; Zhenjiang L; Heuchel R; Schwenk JM; Permert J; Maeurer MJ; Ringden O
Article: ANNALS OF SURGICAL ONCOLOGY. 2017;24(4):1120-1126

Survival Analysis and Risk for Progression of Intraductal Papillary Mucinous Neoplasia of the Pancreas (IPMN) Under Surveillance: A Single-Institution Experience.

Del Chiaro M; Ateeb Z; Hansson MR; Rangelova E; Segersvärd R; Kartalis N; Ansorge C; Löhr MJ; Arnelo U; Verbeke C
Article: LANCET. 2017;389(10073):1011-1024

Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial.

Neoptolemos JP; Palmer DH; Ghaneh P; Psarelli EE; Valle JW; Halloran CM; Faluyi O; O'Reilly DA; Cunningham D; Wadsley J; Darby S; Meyer T; Gillmore R; Anthoney A; Lind P; Glimelius B; Falk S; Izbicki JR; Middleton GW; Cummins S; Ross PJ; Wasan H; McDonald A; Crosby T; Ma YT; Patel K; Sherriff D; Soomal R; Borg D; Sothi S; Hammel P; Hackert T; Jackson R; Büchler MW; European Study Group for Pancreatic Cancer
Article: EUROPEAN JOURNAL OF ONCOLOGY NURSING. 2017;26:36-41

Symptoms and self-care following pancreaticoduodenectomy: Perspectives from patients and healthcare professionals - Foundation for an interactive ICT application.

Gustavell T; Sundberg K; Frank C; Wengström Y; Browall M; Segersvärd R; Langius-Eklöf A
Article: LANGENBECKS ARCHIVES OF SURGERY. 2016;401(8):1241-1247

Cattell-Braasch maneuver combined with local hypothermia during superior mesenteric artery resection in pancreatectomy.

Westermark S; Rangelova E; Ansorge C; Lundell L; Segersvärd R; Del Chiaro M
Article: EUROPEAN RADIOLOGY. 2016;26(11):4021-4029

Multidetector CT of pancreatic ductal adenocarcinoma: Effect of tube voltage and iodine load on tumour conspicuity and image quality.

Loizou L; Albiin N; Leidner B; Axelsson E; Fischer MA; Grigoriadis A; Del Chiaro M; Segersvärd R; Verbeke C; Sundin A; Kartalis N
Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2016;34(18_suppl):lba4006

ESPAC-4: A multicenter, international, open-label randomized controlled phase III trial of adjuvant combination chemotherapy of gemcitabine (GEM) and capecitabine (CAP) versus monotherapy gemcitabine in patients with resected pancreatic ductal adenocarcinoma.

Neoptolemos JP; Palmer D; Ghaneh P; Valle JW; Cunningham D; Wadsley J; Meyer T; Anthoney A; Glimelius B; Falk S; Segersvard R; Izbicki JR; Middleton GW; Ross PJ; Wasan H; Mcdonald A; Crosby TDL; Psarelli EE; Hammel P; Buchler MW
Journal article: PANCREATOLOGY. 2016;16(3):s73

Risk of IPMNs, cancer and progression of pancreatic findings in a population of individual at risk for pancreas cancer who underwent surveillance

Del Chiaro M; Morgell A; Persson S; Arnelo U; Segersvärd R; Ansorge C; Löhr M
Journal article: PANCREATOLOGY. 2016;16(3):s84

The role of preoperative albumin value to improve preoperative treatments in patients with pancreatic adenocarcinoma. A multicenter retrospective analysis of preoperative albumin values

Coppola A; Stauffer JA; Segersvärd R; Del Chiaro M; Asbun HJ
Article: CRITICAL CARE. 2016;20(1):113

Leakage of albumin in major abdominal surgery.

Norberg Å; Rooyackers O; Segersvärd R; Wernerman J
Article: GUT. 2016;65(2):305-312

Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas).

Jais B; Rebours V; Malleo G; Salvia R; Fontana M; Maggino L; Bassi C; Manfredi R; Moran R; Lennon AM; Zaheer A; Wolfgang C; Hruban R; Marchegiani G; Fernández Del Castillo C; Brugge W; Ha Y; Kim MH; Oh D; Hirai I; Kimura W; Jang JY; Kim SW; Jung W; Kang H; Song SY; Kang CM; Lee WJ; Crippa S; Falconi M; Gomatos I; Neoptolemos J; Milanetto AC; Sperti C; Ricci C; Casadei R; Bissolati M; Balzano G; Frigerio I; Girelli R; Delhaye M; Bernier B; Wang H; Jang KT; Song DH; Huggett MT; Oppong KW; Pererva L; Kopchak KV; Del Chiaro M; Segersvard R; Lee LS; Conwell D; Osvaldt A; Campos V; Aguero Garcete G; Napoleon B; Matsumoto I; Shinzeki M; Bolado F; Fernandez JMU; Keane MG; Pereira SP; Acuna IA; Vaquero EC; Angiolini MR; Zerbi A; Tang J; Leong RW; Faccinetto A; Morana G; Petrone MC; Arcidiacono PG; Moon JH; Choi HJ; Gill RS; Pavey D; Ouaïssi M; Sastre B; Spandre M; De Angelis CG; Rios-Vives MA; Concepcion-Martin M; Ikeura T; Okazaki K; Frulloni L; Messina O; Lévy P
Article: JOURNAL OF IMMUNOTHERAPY. 2016;39(2):81-89

Expansion of Tumor-reactive T Cells From Patients With Pancreatic Cancer.

Meng Q; Liu Z; Rangelova E; Poiret T; Ambati A; Rane L; Xie S; Verbeke C; Dodoo E; Del Chiaro M; Löhr M; Segersvärd R; Maeurer MJ
Article: UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2015;3(6):551-560

Outcome of probe-based confocal laser endomicroscopy (pCLE) during endoscopic retrograde cholangiopancreatography: A single-center prospective study in 45 patients.

Löhr J-M; Lönnebro R; Stigliano S; Haas SL; Swahn F; Enochsson L; Noel R; Segersvärd R; Del Chiaro M; Verbeke CS; Arnelo U
Article: CLINICAL CHEMISTRY. 2015;61(11):1408-1416

Variant Profiling of Candidate Genes in Pancreatic Ductal Adenocarcinoma.

Huang J; Löhr J-M; Nilsson M; Segersvärd R; Matsson H; Verbeke C; Heuchel R; Kere J; Iafrate AJ; Zheng Z; Ye W
Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2015;13(6):1162-1169

Association between pancreatic intraductal papillary mucinous neoplasms and extrapancreatic malignancies.

Marchegiani G; Malleo G; D'Haese JG; Wenzel P; Keskin M; Pugliese L; Borin A; Benning V; Nilsson L; Oruc N; Segersvard R; Friess H; Schmid R; Löhr M; Maisonneuve P; Bassi C; Ceyhan GO; Salvia R; Del Chiaro M
Article: JAMA SURGERY. 2015;150(6):512-518

Short-term Results of a Magnetic Resonance Imaging-Based Swedish Screening Program for Individuals at Risk for Pancreatic Cancer.

Del Chiaro M; Verbeke CS; Kartalis N; Pozzi Mucelli R; Gustafsson P; Hansson J; Haas SL; Segersvärd R; Andren-Sandberg Å; Löhr J-M
Article: JOURNAL OF GASTROINTESTINAL SURGERY. 2015;19(3):492-497

Pancreas-preserving duodenectomy is a safe alternative to high-risk pancreatoduodenectomy for premalignant duodenal lesions.

Rangelova E; Blomberg J; Ansorge C; Lundell L; Segersvärd R; Del Chiaro M
Article: PLOS ONE. 2015;10(8):e0136371

Albumin Kinetics in Patients Undergoing Major Abdominal Surgery.

Norberg Å; Rooyackers O; Segersvärd R; Wernerman J
Article: JOURNAL OF THE PANCREAS. 2014;15(6):597-599

The use of LigaSure™ Does not Affect Histologic Margin Assessment in Pancreatoduodenectomy (PD) specimens.

Del Chiaro M; Blomberg J; Segersvärd R; Rangelova E; Ansorge C; Verbeke C
Article: PANCREATOLOGY. 2014;14(6):510-514

Single-operator pancreatoscopy is helpful in the evaluation of suspected intraductal papillary mucinous neoplasms (IPMN).

Arnelo U; Siiki A; Swahn F; Segersvärd R; Enochsson L; del Chiaro M; Lundell L; Verbeke CS; Löhr J-M
Article: WORLD JOURNAL OF SURGERY. 2014;38(9):2422-2429

Correlation between preoperative imaging and intraoperative risk assessment in the prediction of postoperative pancreatic fistula following pancreatoduodenectomy.

Frozanpor F; Loizou L; Ansorge C; Lundell L; Albiin N; Segersvärd R
Article: WORLD JOURNAL OF SURGERY. 2014;38(9):2412-2421

Assessing surgical quality: comparison of general and procedure-specific morbidity estimation models for the risk adjustment of pancreaticoduodenectomy outcomes.

Ansorge C; Lindström P; Strömmer L; Blomberg J; Lundell L; Andrén-Sandberg A; Del Chiaro M; Segersvärd R
Article: FAMILIAL CANCER. 2014;13(2):227-229

Is intraductal tubulopapillary neoplasia a new entity in the spectrum of familial pancreatic cancer syndrome?

Del Chiaro M; Mucelli RP; Blomberg J; Segersvärd R; Verbeke C
Article: ANNALS OF SURGICAL ONCOLOGY. 2014;21(5):1539-1544

Comparison of preoperative conference-based diagnosis with histology of cystic tumors of the pancreas.

Del Chiaro M; Segersvärd R; Pozzi Mucelli R; Rangelova E; Kartalis N; Ansorge C; Arnelo U; Blomberg J; Löhr M; Verbeke C
Article: BRITISH JOURNAL OF SURGERY. 2013;101(2):100-108

Diagnostic value of abdominal drainage in individual risk assessment of pancreatic fistula following pancreaticoduodenectomy.

Ansorge C; Nordin JZ; Lundell L; Strömmer L; Rangelova E; Blomberg J; Del Chiaro M; Segersvärd R
Article: PANCREATOLOGY. 2013;13(6):570-575

Computed tomography staging of pancreatic cancer: a validation study addressing interobserver agreement.

Loizou L; Albiin N; Ansorge C; Andersson M; Segersvärd R; Leidner B; Sundin A; Lundell L; Kartalis N
Article: DIGESTIVE AND LIVER DISEASE. 2013;45(9):703-711

European experts consensus statement on cystic tumours of the pancreas.

Del Chiaro M; Verbeke C; Salvia R; Klöppel G; Werner J; McKay C; Friess H; Manfredi R; Van Cutsem E; Löhr M; Segersvärd R; European Study Group on Cystic Tumours of the Panc
Article: WORLD JOURNAL OF GASTROINTESTINAL PATHOPHYSIOLOGY. 2013;4(2):37-42

Impact of body mass index for patients undergoing pancreaticoduodenectomy.

Del Chiaro M; Rangelova E; Ansorge C; Blomberg J; Segersvärd R
Article: DIGESTIVE DISEASES. 2013;31(1):43-50

Conservative treatment of chronic pancreatitis.

Löhr J-M; Haas SL; Lindgren F; Enochsson L; Hedström A; Swahn F; Segersvärd R; Arnelo U
Article: WORLD JOURNAL OF SURGERY. 2013;37(1):179-184

Portal venous system thrombosis after pancreatic resection.

Ansari D; Ansorge C; Andrén-Sandberg A; Ansari D; Segersvärd R
Article: JOURNAL OF THE PANCREAS. 2012;13(6):654-659

Management of alcohol use disorders in patients with chronic pancreatitis.

Lang MB; Segersvärd R; Grundsten M; Segerdahl M; Arnelo U; Permert J; Franck J; Löhr M; Tsai JA
Article: PROTEOMICS CLINICAL APPLICATIONS. 2012;6(9-10):486-496

Serum proteome profiling of pancreatitis using recombinant antibody microarrays reveals disease-associated biomarker signatures.

Sandström A; Andersson R; Segersvärd R; Löhr M; Borrebaeck CAK; Wingren C
Article: EUROPEAN RADIOLOGY. 2012;22(10):2186-2192

Optimising diffusion-weighted MR imaging for demonstrating pancreatic cancer: a comparison of respiratory-triggered, free-breathing and breath-hold techniques.

Kartalis N; Loizou L; Edsborg N; Segersvärd R; Albiin N
Article: WORLD JOURNAL OF SURGERY. 2012;36(8):1858-1865

Preoperative pancreas CT/MRI characteristics predict fistula rate after pancreaticoduodenectomy.

Frozanpor F; Loizou L; Ansorge C; Segersvärd R; Lundell L; Albiin N
Article: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2012;308(2):147-156

Effect of adjuvant chemotherapy with fluorouracil plus folinic acid or gemcitabine vs observation on survival in patients with resected periampullary adenocarcinoma: the ESPAC-3 periampullary cancer randomized trial.

Neoptolemos JP; Moore MJ; Cox TF; Valle JW; Palmer DH; McDonald AC; Carter R; Tebbutt NC; Dervenis C; Smith D; Glimelius B; Charnley RM; Lacaine F; Scarfe AG; Middleton MR; Anthoney A; Ghaneh P; Halloran CM; Lerch MM; Oláh A; Rawcliffe CL; Verbeke CS; Campbell F; Büchler MW; European Study Group for Pancreatic Cancer
Article: BRITISH JOURNAL OF SURGERY. 2012;99(8):1076-1082

Structured intraoperative assessment of pancreatic gland characteristics in predicting complications after pancreaticoduodenectomy.

Ansorge C; Strömmer L; Andrén-Sandberg Å; Lundell L; Herrington MK; Segersvärd R
Article: ANNALS OF SURGERY. 2012;255(6):1032-1036

The effect of prophylactic transpapillary pancreatic stent insertion on clinically significant leak rate following distal pancreatectomy: results of a prospective controlled clinical trial.

Frozanpor F; Lundell L; Segersvärd R; Arnelo U
Article: CANCER RESEARCH. 2012;72(10):2481-2490

Identification of serum biomarker signatures associated with pancreatic cancer.

Wingren C; Sandström A; Segersvärd R; Carlsson A; Andersson R; Löhr M; Borrebaeck CAK
Article: BRITISH JOURNAL OF SURGERY. 2011;99(1):104-111

Early intraperitoneal metabolic changes and protease activation as indicators of pancreatic fistula after pancreaticoduodenectomy.

Ansorge C; Regner S; Segersvärd R; Strömmer L
Article: PANCREATOLOGY. 2011;11(5):464-468

Validation of the harmless acute pancreatitis score in predicting nonsevere course of acute pancreatitis.

Oskarsson V; Mehrabi M; Orsini N; Hammarqvist F; Segersvärd R; Andrén-Sandberg A; Sadr Azodi O
Article: DIABETES. 2010;59(10):2569-2578

Clinical and experimental pancreatic islet transplantation to striated muscle: establishment of a vascular system similar to that in native islets.

Christoffersson G; Henriksnäs J; Johansson L; Rolny C; Ahlström H; Caballero-Corbalan J; Segersvärd R; Permert J; Korsgren O; Carlsson P-O; Phillipson M
Article: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2010;304(10):1073-1081

Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial.

Neoptolemos JP; Stocken DD; Bassi C; Ghaneh P; Cunningham D; Goldstein D; Padbury R; Moore MJ; Gallinger S; Mariette C; Wente MN; Izbicki JR; Friess H; Lerch MM; Dervenis C; Oláh A; Butturini G; Doi R; Lind PA; Smith D; Valle JW; Palmer DH; Buckels JA; Thompson J; McKay CJ; Rawcliffe CL; Büchler MW; European Study Group for Pancreatic Cancer
Article: JOURNAL OF THE PANCREAS. 2010;11(5):439-443

Impact of pancreatic gland volume on fistula formation after pancreatic tail resection.

Frozanpor F; Albiin N; Linder S; Segersvärd R; Lundell L; Arnelo U
Article: EUROPEAN SURGICAL RESEARCH. 2010;45(3-4):134-137

Pancreatic cancer cells expressing hypoxia-inducible factor-1α tend to be adjacent to intratumoral blood vessels.

Cheng B-Q; Segersvärd R; Permert J; Wang F
Article: OBESITY. 2008;16(1):23-28

Obesity alters cytokine gene expression and promotes liver injury in rats with acute pancreatitis.

Segersvärd R; Tsai JA; Herrington MK; Wang F
Article: AMERICAN JOURNAL OF PATHOLOGY. 2007;170(2):469-477

Hypoxia inducible factor-1 mediates effects of insulin on pancreatic cancer cells and disturbs host energy homeostasis.

Wang F; Li SS; Segersvärd R; Strömmer L; Sundqvist K-G; Holgersson J; Permert J
Article: CELL AND TISSUE RESEARCH. 2005;320(2):251-258

mRNA for pancreatic uncoupling protein 2 increases in two models of acute experimental pancreatitis in rats and mice.

Segersvärd R; Rippe C; Duplantier M; Herrington MK; Isaksson B; Adrian TE; Erlanson-Albertsson C; Permert J
Article: NEOPLASIA. 2005;7(4):417-425

LY293111 improves efficacy of gemcitabine therapy on pancreatic cancer in a fluorescent orthotopic model in athymic mice.

Hennig R; Ventura J; Segersvard R; Ward E; Ding X-Z; Rao SM; Jovanovic BD; Iwamura T; Talamonti MS; Bell RH; Adrian TE
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2004;39(1):74-80

Impact of chronic and acute high-fat feeding on acute experimental pancreatitis complicated by endotoxinaemia.

Segersvärd R; Sylván M; Lempinen M; Larsson J; Permert J
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2002;37(1):104-111

Obstructive jaundice results in increased liver expression of uncoupling protein 2 and intact skeletal muscle glucose metabolism in the rat.

Isaksson B; Rippe C; Simonoska R; Holm JE; Glaumann H; Segersvärd R; Larsson J; Erlanson-Albertsson C; Permert J
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2001;36(6):658-663

Obesity increases the severity of acute experimental pancreatitis in the rat.

Segersvärd R; Sylván M; Herrington M; Larsson J; Permert J
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All other publications

Conference publication: JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. 2020;231(4):E53

Centralization Improves Survival of Pancreatic Cancer by Increased Operative Indication and Resection Rate: A Population-Based Study

Rangelova EB; Ebrahim F; Sharp L; Henriksson R; Segersvard R
Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2020;38(15)

ESPAC-4: A multicenter, international, open-label randomized controlled phase III trial of adjuvant combination chemotherapy of gemcitabine (GEM) and capecitabine (CAP) versus monotherapy gemcitabine in patients with resected pancreatic ductal adenocarcinoma: Five year follow-up.

Neoptolemos JP; Palmer DH; Ghaneh P; Valle JW; Cunningham D; Wadsley J; Meyer T; Anthoney A; Glimelius B; Falk S; Segersvard R; Middleton GW; Ross PJ; Wasan HS; McDonald A; Crosby TDL; Psarelli EE; Hammel P; Hackert T; Buchler MW
Conference publication: QUALITY OF LIFE RESEARCH. 2018;27:S20-S21

Routine use of patient reported symptoms assisted with an interactive app decreased symptom burden after surgery for pancreatic cancer

Gustavell T; Sundberg K; Segersvard R; Wengstrom Y; Langius-Eklof A
Review: UPDATES IN SURGERY. 2016;68(3):257-263

Are there still indications for total pancreatectomy?

Del Chiaro M; Rangelova E; Segersvärd R; Arnelo U
Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2016;34(18)

ESPAC-4: A multicenter, international, open-label randomized controlled phase III trial of adjuvant combination chemotherapy of gemcitabine (GEM) and capecitabine (CAP) versus monotherapy gemcitabine in patients with resected pancreatic ductal adenocarcinoma.

Neoptolemos JP; Palmer D; Ghaneh P; Valle JW; Cunningham D; Wadsley J; Meyer T; Anthoney A; Glimelius B; Falk S; Segersvard R; Izbicki JR; Middleton GW; Ross PJ; Wasan H; Mcdonald A; Crosby TDL; Psarelli EE; Hammel P; Buchler MW
Conference publication: PANCREAS. 2016;45(10):1495

Comparison of Remnant Invagination and Duct-To-Mucosa Pancreaticojejunostomy Following Whipples Resection: Randomized Clinical Trial in Patients at High Risk of Postoperative Pancreatic Fistula

Ansorge C; Sanjeevi S; Del Chiaro M; Bjornsson B; Sand J; Segersvard R; Lundell L; Andren-Sandberg A
Book chapter: CYSTIC TUMORS OF THE PANCREAS. 2016;p. 171-175

Comparison Between the IAP and European Guidelines for the Management of Cystic Lesions of the Pancreas

Segersvärd R; Ohtsuka T; Rangelova E; Tanaka M
Published conference paper: JOURNAL OF GASTROINTESTINAL SURGERY. 2015;19(12):2264-2268

Cattell-Braasch Maneuver Combined with Artery-First Approach for Superior Mesenteric-Portal Vein Resection During Pancreatectomy.

Del Chiaro M; Segersvärd R; Rangelova E; Coppola A; Scandavini CM; Ansorge C; Verbeke C; Blomberg J
Book chapter: PANCREATIC CANCER, CYSTIC NEOPLASMS AND ENDOCRINE TUMORS. 2015;p. 54-58

Risk/Benefit of Total Pancreatectomy for Pancreatic Cancer: Are There Indications?

Andrén‐Sandberg Å; Segersvärd R
Review: WORLD JOURNAL OF GASTROENTEROLOGY. 2014;20(34):12118-12131

Early detection and prevention of pancreatic cancer: is it really possible today?

Del Chiaro M; Segersvärd R; Lohr M; Verbeke C
Editorial comment: BIOMED RESEARCH INTERNATIONAL. 2014;2014:963416-2

Innovations in pancreatic surgery.

Hirota M; Sand J; Segersvärd R; Cirocchi R
Review: BIOMED RESEARCH INTERNATIONAL. 2014;2014:920492-5

The state of the art of robotic pancreatectomy.

Del Chiaro M; Segersvärd R
Conference publication: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2014;29:48

Pancreatic serous cystadenoma-related mortality is almost nil - results of a multinational study under the auspices of the International Association of Pancreatology and the European Pancreatic Club

Jais B; Rebours V; Tang Y; Gill R; Leong RWL; Malleo G; Salvia R; Moran R; Lennon AM; Marchegiani G; Castillo CF; Ha Y; Kim MH; Hirai I; Kimura W; Jang JY; Kim SW; Kang CM; Lee WJ; Crippa S; Falconi M; Gomatos IP; Neoptolemos J; Milanetto AC; Sperti C; Ricci C; Casadei R; Bissolati M; Balzano G; Frigerio I; Girelli R; Delhaye M; Bernier B; Wang H; Jang KT; Song DH; Huggett M; Oppong K; Pererva L; Kopchak K; Chiaro MD; Segersvard R; Lee LS; Conwell D; Oswaldt A; Campos V; Garcete GA; Napoleon B; Levy P
Conference publication: BONE MARROW TRANSPLANTATION. 2014;49:S99

ALLOGENEIC STEM CELL TRANSPLANTATION IN PANCREATIC CARCINOMA

Omazic B; Segersvard R; Hassan Z; Mattsson J; Terman A; Ghazi S; Albiin N; Lohr M; Permert J; Ringden O
Conference publication: PANCREAS. 2014;43(8):1388

Are IPMN of the Pancreas Associated to an Increased Prevalence or Incidence of Extra-Pancreatic Neoplasms? A Multicentre European Observational Study

Marchegiani G; D'Haese JG; Keskin M; Wenzel P; Pugliese L; Malleo G; Borin A; Nilsson L; Benning V; Oruc N; Segersvard R; Salvia R; Ceyhan GO; del Chiaro M
Conference publication: PANCREAS. 2014;43(8):1353

Follow-up Strategy for IPMN of the Pancreas is Safe

Del Chiaro M; Segersvard R; Nilsson L; Blomberg J; Rangelova E; Ansorge C; Pozzi-Mucelli R; Kartalis N; Lohr M; Arnelo U; Verbeke C
Editorial comment: PANCREATOLOGY. 2013;13(3):312-313

Enucleation of branch duct-IPMN in a transplant patient.

Del Chiaro M; Albiin N; Segersvärd R
Conference publication: DIAGNOSIS. 2012;:b5

Abstract B5: Identification of serum biomarker signatures associated with pancreatic cancer.

Sandström A; Wingren C; Segersvärd R; Carlsson A; Andersson R; Löhr M; Borrebaeck CAK
Conference publication: PANCREAS. 2010;39(8):1346

R1 Rate and Lymph Node Status in Pancreatic Cancer is Determined by Intratumoral Factors

Segersvard R; Leifler A; Ghazi S; Jonsson F; Nilsson M; Permert J
Conference publication: DIABETOLOGIA. 2010;53:S60

Clinical and experimental pancreatic islet transplantation to striated muscle: Establishment of a vascular system similar to that in native islets

Christoffersson G; Henriksnas J; Johansson L; Rolny C; Ahlstrom H; Caballero-Corbalan J; Segersvard R; Permert J; Korsgren O; Carlsson P-O; Phillipson M
Conference publication: 2009;:1-8

Efficiency in Treatment Discussions: A Field Study of Time Related Aspects in Multi-Disciplinary Team Meetings

Groth K; Frykholm O; Segersvärd R; Isaksson B; Permert J
Conference publication: PANCREAS. 2009;38(8):1023-1024

Confocal Laser Endomicroscopy of the Pancreatobiliary Ducts

Lohr M; Swahn F; Enochsson L; Ghazi S; Segersvard R; Arnelo U
Conference publication: PANCREAS. 2008;37(4):492

EVALUATION OF A COMPLICATION GRADING SYSTEM FOR PANCREATIC SURGERY

Rangelova E; Permert J; Ansorge C; Strommer L; Andren-Sandberg A; Segersvard R
Meeting abstract: PANCREAS. 2007;35(4):426

Islet amyloid polypeptide plays a proinflammatory role in acute pancreatitis by upregulation of chemokine gene expression

Segersvard R; Tsai J; Capitano A; Arnelo U
Meeting abstract: PANCREAS. 2006;33(4):497

High mobility group box-1 (HMGB1) augments pancreatic necrosis in taurocholate induced pancreatitis in rats

Segersvärd R; Palmblad K; Tsai J; Capitano A; Andersson U; Permert J
Meeting abstract: GASTROENTEROLOGY. 2003;124(4):a504

Expression of 5-lipoxygenase (5-LOX) and cyclooxgenase-2 (COX-2) in rat acinar cells increases in acute necrotizing pancreatitis

Segersvard R; Hennig R; Denham W; Ding XZ; Rao SM; Permert J; Adrian TE
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Employments

Affiliated to Research, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2022-2024

Degrees and Education

Doctor Of Philosophy, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2005

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