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About me

Director, Center for Apheresis and Stem Cell Handling

Karolinska University Hospital

 

Associate professor of Renal Medicine  & Research Group Leader

Department of Medical Biochemistry and Biophysics, Karolinska institutet

 

Wallenberg Clinical Research Fellow 2014-2017

 

Education

MD, Specialist in Nephrology and Interal Medicine 

PhD, Associate professor

Research description

Translational research into renal nutrient handling.

We work with cell lines, primary cell cultures, transgenic animals (zebrafish and mice) and human tissues to discover novel pathophysiological pathways of relevance for complications in patients with reduced renal function. Our data is generated using conventional and novel biomedical methods in combination with advanced imaging, proteomic analysis and single-cell RNA sequencing.

About chronic kidney disease

Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are significant public health problems in both developed and developing countries. Despite many ethiologies, the CKD phenotype is remarkably simillar and responsible for the premature death, elevated morbidity and very high costs of this patient group Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization.
Go A, Chertow G, Fan D, McCulloch C, Hsu C
N. Engl. J. Med. 2004 09;351(13):1296-305. In the US, nearly 25 percent of the Medicare budget is used to treat people with CKD and ESRD (http://www.usrds.org/).

 

Teaching portfolio

Associate Professor of Nephrology teaching clinical and pre-clinical courses at several KI programs.

Lectures and seminars as part of the Biochemistry education at the Department.

 

 

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