News archive Jari Tiihonen

Combination therapy might be beneficial in schizophrenia

20 Feb 2019

Combining certain types of two antipsychotic agents in the maintenance treatment of schizophrenia is associated with a lower risk of relapse than using monotherapy. This is suggested in a paper published by researchers at Karolinska Institutet in the journal JAMA Psychiatry . The current treatment...
Clinical Neuroscience

Lithium treatment for bipolar disorder linked to lowest risk of rehospitalisation

28 Feb 2018

Individuals with bipolar disorder have the lowest risk of rehospitalisation if treated with lithium, according to a study from Karolinska Institutet published in JAMA Psychiatry . Long-acting injections of antipsychotics were also effective, reducing the risk of rehospitalisation by 30 per cent...
DrugMental Ill-HealthPsychiatric disordersPsychiatry

Fewer relapses in schizophrenia with long-acting injections

08 Jun 2017

The risk of relapse among patients with schizophrenia differs depending on what drug is administered, suggests a register study from Karolinska Institutet in Sweden published in JAMA Psychiatry. Clozapine and long-acting injections were linked to fewer re-admissions to hospital than other...
DrugPsychiatric disordersPsychiatry

Study analyses link between psychotropic drugs and homicide risk

01 Jun 2015

A new study published in the journal World Psychiatry shows that the use of certain drugs that affect the central nervous system may be associated with an increased risk of committing a homicide. The greatest risk was recorded in the use of tranquillizing benzodiazepines and painkillers, while anti...
PharmacologyPsychiatry

Genes linked to repeated violent crime

29 Oct 2014

An international research team led from Karolinska Institutet have identified two genes that may be linked to an increased disposition to engage in repeated acts of violence. The findings are being published in the journal Molecular Psychiatry , and are based on genetic analysis of people convicted...
GeneticsPsychiatry