PhD Student in the lab of Ernest Arenas
MSc - Stockholm University
BSc - University of Wisconsin - Madison
Interested in studying and characterizing the function and mechanisms by which components of the Wnt/PCP signalling pathway regulate the development of midbrain DA neurons in vivo and application of Wnts to improve protocols for the DA differentiation of stem cells. Also interested in single-cell heterogeneity in the developing midbrain.
Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP.
Sci Signal 2017 Aug;10(493):
Translation of WNT developmental programs into stem cell replacement strategies for the treatment of Parkinson's disease.
Br. J. Pharmacol. 2017 Dec;174(24):4716-4724
Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells.
Cell 2016 Oct;167(2):566-580.e19
A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease.
EMBO J. 2016 09;35(18):1963-78
Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system.
Science 2016 Jun;352(6291):1326-1329
Analysis of neural crest-derived clones reveals novel aspects of facial development.
Sci Adv 2016 08;2(8):e1600060