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Publications

Development of a computerised decisions support system for renal risk drugs targeting primary healthcare
Helldén A, Al-aieshy F, Bastholm-rahmner P, Bergman U, Gustafsson Ll, Höök H, et al
BMJ open 2015;5(7):e006775-

Ganciclovir concentrations in the cerebral extracellular space after valganciclovir treatment; a case study
Peredo I, Helldén A, Wolmer-solberg N, Pohanka A, Stragliotto G, Rahbar A, et al
BMJ case reports 2015;2015():-

Lower CYP2C9 activity in Turkish patients with Behçet's disease compared to healthy subjects: a down-regulation due to inflammation?
Goktaş Mt, Hatta F, Karaca O, Kalkisim S, Kilic L, Akdogan A, et al
European journal of clinical pharmacology 2015;71(10):1223-8

Implications of serum creatinine measurements on GFR estimation and vancomycin dosing in children
Neuman G, Nulman I, Adeli K, Koren G, Colantonio Da, Hellden A
JOURNAL OF CLINICAL PHARMACOLOGY 2014;54(7):785-91

Differential diagnosis of central nervous system involvement in a patient treated with acyclovir
Von Euler M, Axelsson G, Helldén A
Therapeutic drug monitoring 2013;35(4):417-9

Erratum to: Adverse Drug Reactions and Impaired Renal Function in Elderly Patients Admitted to the Emergency Department (vol 26, pg 595, 2009)
Hellden A, Bergman U, Von Euler M, Hentschke M, Odar-cederlof I, Ohlen G
DRUGS & AGING 2013;30(12):1043-1045

Renal function estimations and dose recommendations for dabigatran, gabapentin and valaciclovir: a data simulation study focused on the elderly
Helldén A, Odar-cederlöf I, Nilsson G, Sjöviker S, Söderström A, Euler Mv, et al
BMJ open 2013;3(4):-

Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A>T and the losartan metabolism phenotype in Swedes
Hatta Fh, Teh Lk, Helldén A, Hellgren Ke, Roh Hk, Salleh Mz, et al
European journal of clinical pharmacology 2012;68(7):1033-42

The dopaminergic stabilizer pridopidine is to a major extent N-depropylated by CYP2D6 in humans
Helldén A, Panagiotidis G, Johansson P, Waters N, Waters S, Tedroff J, et al
European journal of clinical pharmacology 2012;68(9):1281-6

Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9
Hellden A, Bergman U, Hellgren Ke, Masquelier M, Remahl In, Odar-cederlof I, et al
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 2010;66(8):791-5

Acute Clozapine Intoxication
Sparve E, Nordberg P, Forsberg S, Hellden A
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 2009;29(3):302-4

Adverse Drug Reactions and Impaired Renal Function in Elderly Patients Admitted to the Emergency Department A Retrospective Study
Hellden A, Bergman U, Von Euler M, Hentschke M, Odar-cederof I, Ohlen G
DRUGS & AGING 2009;26(7):595-606

[Antithyroid drug-induced agranulocytosis. A rare but dreaded condition]
Lehtihet M, Zedenius J, Helldén A, Axelsson R, Calissendorff J
Lakartidningen 2009;106(41):2607-8

Cystatin C estimated Glomerular Filtration Rate (eGFR) in the Elderly.
Back R, Thylen P, Klarin I, Bergman U, Odar-cederlof I, Hellden A
CLINICAL CHEMISTRY 2009;55(6):A194-A194

PHARMACOVIGILANCE AND PATIENT SAFETY - A PLEA FOR REGIONAL PHARMACOVIGILANCE CENTRES
Bergman U, Mejyr S, Odar-cederlof I, Hellden A, Bradley T, Sjolin-forsberg G
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 2009;:30-30

THE INCIDENCE OF ACICLOVIR-INDUCED NEUROPSYCHIATRIC SYMPTOMS IN STOCKHOLM
Hellden A, Odar-cederlof I, Bergman U, Orvell C, Stahle L
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 2009;:30-30

[Adverse drug effect as cause of hospital admission. Common drugs are the major part according to the cross-sectional study]
Odar-cederlöf I, Oskarsson P, Ohlén G, Tesfa Y, Bergendal A, Helldén A, et al
Lakartidningen 2008;105(12-13):890-3

Pulmonary embolism associated with the use of anabolic steroids
Liljeqvist S, Hellden A, Bergman U, Soderberg M
EUROPEAN JOURNAL OF INTERNAL MEDICINE 2008;19(3):214-5

Aciclovir-induced CNS adverse drug reactions. Analysis of the pprincipal metabolite of aciclovir, 9-carboxymethoxymethyl-guanine (CMMG), in serum as a diagnostic tool to differentiate between herpes encephalitis and severe side effects of aciclovir or valaciclovir
Hellden A, Odar-cederlof I, Stahle L
THERAPEUTIC DRUG MONITORING 2007;29(4):550-551

Aciclovir-induced neurotoxicity in hematological patients. Measurement of the aciclovir main metabolite cmmg may differentiate between adverse drug reactions and herpes infections
Hellden A, Odar-cederlof O
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 2007;:232-232

Death delusion
Hellden A, Odar-cederlof I, Larsson K, Fehrman-ekholm I, Linden T
BRITISH MEDICAL JOURNAL 2007;335(7633):1305-

[Risk of CNS adverse effects of aciclovir and valaciclovir. Watch the renal function in treatment of herpes simplex and herpes zoster]
Helldén A, Bergman U, Dwyer R, Medin C, Molanaei H, Ståhle L, et al
Lakartidningen 2007;104(24-25):1916-20

Elderly patients in stockholm are commonly prescribed drugs that require precautions in relation to reduced renal function
Odar-cederlof I, Sjoviker S, Ronge S, Hellden A, Soderstrom A, Jacobsson L, et al
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 2006;:S100-S101

The aciclovir metabolite CMMG is detectable in the CSF of subjects with neuropsychiatric symptoms during aciclovir and valaciclovir treatment
Hellden A, Lycke J, Vander T, Svensson Jo, Odar-cederlof I, Stahle L
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 2006;57(5):945-9

Aciclovir induced posterior leucoencephalopathy
Mahad D, Jarvis J, Chinnery Pf, Mitra D, Gholkar A, Hellden A
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY 2005;76(9):1308-9

Acyclovir-induced neurotoxicity increases the risk for thromboembolic events, cerebral hemorrhage and death
Hellden A, Cederlof Io, Stahle L
THERAPEUTIC DRUG MONITORING 2005;27(2):221-221

Renal function underestimated in elderly hospitalised patients with adverse drug reactions
Hellden A, Johansson M, Ohlen G, Bergman U
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 2004;31(11):A221-A221

Aciclovir and valaciclovir neurotoxicity in patient's with renal failure - Reply
Hellden A, Stahle L
NEPHROLOGY DIALYSIS TRANSPLANTATION 2003;18(12):2680-2681

High serum concentrations of the acyclovir main metabolite 9-carboxymethoxymethylguanine in renal failure patients with acyclovir-related neuropsychiatric side effects: an observational study
Hellden A, Odar-cederlof I, Diener P, Barkholt L, Medin C, Svensson Jo, et al
NEPHROLOGY DIALYSIS TRANSPLANTATION 2003;18(6):1135-41

Pre-emptive oral vs. IV ganciclovir therapy against cytomegalovirus disease after allogeneic hematopoietic stem cell transplantation (Hsct) in patients with solid tumor
Barkholt L, Lewensohn-fuchs I, Hentschke P, Stahle L, Hellden A, Ringden O
BONE MARROW TRANSPLANTATION 2002;:S192-S192

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