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Education

2011- PhD, Epidemiology/Biostatistic, Karolinska Institute, Sweden.

2010 Two-years post-graduate degree (Master of Science) in biostatistics and experimental statistic science. Vote: 110/110 cum laude. University of Milano-Bicocca, Italy.

2007 Bachelor in Statistic Science (Vote: 108/110). University of Milano-Bicocca, Italy.

Research description

A large number of new risk factors for cardiovascular diseases have been discovered in the last years and new -omics technologies will reveal more of them. It is important to understand which of these risk factors (markers) might have a utility in clinical practice. In my PhD thesis I will explore the predictive ability of recently discovered risk factors. Specifically, I will study the additive value of metabolomics and genetic markers for preventing cardiovascular diseases. The evaluation of the clinical utility of newly discovered markers is not straightforward. Several measures have been proposed, but most of the current methods did not include information regarding treatment effect or the impact on a population level. Moreover, it is not clear how these measures can be applied in sampling study design such as case-cohort and nested case-control design. These topics will also be part of my thesis. I’m also interested in how the large amount of results generated by GWAS studies are related to each other and how they can be summarized and used for different phenotypes.

Academic honours, awards and prizes

2013 Svenska Läkaresällskapets Forskningsdelegationen travel grant: “Oral Presentation: Non-targeted metabolite profiling in large human population-based studies; a new data analysis workflow and metabolome-wide association study of C-reactive protein” 

2013 Swedish Heart and Lung foundation travel grant: “Oral Presentation: Non-targeted metabolite profiling in large human population-based studies; a new data analysis workflow and metabolome-wide association study of C-reactive protein”

2013 Karolinska Institutet travel grant: “ASHG meeting 2013, Boston, U.S.A”

 2012 Karolinska Institutet travel grant: “ASHG meeting 2012, San Francisco, U.S.A”

2012 Swedish Council for Working Life and Social Research: “16th Human Genome Meeting, Sydney, Australia, 11-14 March 2012”

2012 Swedish Heart and Lung foundation travel grant: “A multi-locus genetic risk score for coronary heart disease improves risk reclassification beyond established risk factors”

2012 Svenska Läkaresällskapets Forskningsdelegationen travel grant: “A multi-locus genetic risk score for coronary heart disease improves risk reclassification beyond established risk factors”

2012 ENGAGE Training and Mobility Program: “Exchange visit to Cecile Janssens’s group at the Erasmus Medical University in Rotterdam”

2011 Swedish Heart and Lung foundation travel grant: “Comparison of apolipoproteins and traditional lipid measures for prediction of major coronary and other cardiovascular events in a Mediterranean male population”

2010 EXTRA Scholarship: “The importance of lipid measures in assessment and evaluation of a risk prediction model for CVD”

2010 Lerici Grant: “The importance of lipid measures in assessment and evaluation of a risk prediction model for CVD”

2008 Erasmus Scholarship at Oslo University College (Høgskolen i Oslo), Oslo, Norway

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