Albert Siegbahn

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About me

I am employed as Medical Physicist at Stockholm South General Hospital
in Stockholm, Sweden (www.sodersjukhuset.se ). I am also Associate
Professor at the Department of Clinical Science and Education at Karolinska
Institutet. My office is located in the radiotherapy section at the
Department of Oncology.
2021 Associate Professor at the Department of Clinical Science and
Education, Karolinska Institutet
2014 Associate Professor at the Department of Physics, Stockholm University
2007 Ph.D.-degree (Dr. rer. nat.) from the Technical University of Munich,
Germany.
2004 – 2007 Ph.D. Student at the European Synchrotron Radiation Facility
in Grenoble, France
2001 Physics studies: M.Sc.-degree from Stockholm University

Articles

Article: CANCERS. 2023;15(24):5736

Dosimetric Comparison of Conventional Radiotherapy, Volumetric Modulated Arc Therapy, and Proton Beam Therapy for Palliation of Thoracic Spine Metastases Secondary to Breast or Prostate Cancer.

Lideståhl A; Fredén E; Siegbahn A; Johansson G; Lind PA
Article: MEDICAL PHYSICS. 2022;49(8):5589-5603

Modeling secondary cancer risk ratios for proton versus carbon ion beam therapy: A comparative study based on the local effect model.

Hufnagl A; Johansson G; Siegbahn A; Durante M; Friedrich T; Scholz M
Journal article: RADIOTHERAPY AND ONCOLOGY. 2022;170:s1255-s1256

PO-1480 Heart dose variability in RT of left breast cancer patients treated in deep inspiration breath hold

Johansson G; Fredén E; Knutsson J; Olin M; Dagertun L; Siegbahn A
Article: CANCERS. 2021;13(20):5153

Estimated Risk of Radiation-Induced Cancer after Thymoma Treatments with Proton- or X-ray Beams.

Lideståhl A; Johansson G; Siegbahn A; Lind PA
Journal article: RADIOTHERAPY AND ONCOLOGY. 2021;161:s1490-s1492

PO-1764 Evaluation of the setup accuracy of a surface scanning system in radiotherapy of breast cancer

Knutsson J; Johansson G; Dagertun L; Olin M; Siegbahn A
Journal article: RADIOTHERAPY AND ONCOLOGY. 2021;161:s1513-s1514

PO-1788 Estimated risk of radiation-induced cancer after thymoma treatments with proton- or x-ray beams

Lideståhl A; Johansson G; Siegbahn A; Lind PA
Article: SCIENTIFIC REPORTS. 2019;9(1):17082

Locomotion and eating behavior changes in Yucatan minipigs after unilateral radio-induced ablation of the caudate nucleus.

Coquery N; Adam J-F; Nemoz C; Janvier R; Livingstone J; Chauvin A; Kefs S; Guerineau C; De Saint Jean L; Ocadiz A; Bouchet A; Bartzsch S; Schültke E; Siegbahn A; Bräuer-Krisch E; Lemasson B; Barbier EL; Laissue J; Balosso J; Val-Laillet D; Serduc R
Article: PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS. 2019;60:120-126

An in silico planning study comparing doses and estimated risk of toxicity in 3D-CRT, IMRT and proton beam therapy of patients with thymic tumours.

Lideståhl A; Mondlane G; Gubanski M; Lind PA; Siegbahn A
Article: RADIATION ONCOLOGY. 2018;13(1):206

Estimation of the risk for radiation-induced liver disease following photon- or proton-beam radiosurgery of liver metastases.

Mondlane G; Ureba A; Gubanski M; Lind PA; Siegbahn A
Article: ANTICANCER RESEARCH. 2018;38(5):2619-2625

Estimation of Risk of Normal-tissue Toxicity Following Gastric Cancer Radiotherapy with Photon- or Scanned Proton-beams.

Mondlane G; Ureba A; Gubanski M; Lind PA; Siegbahn A
Article: MEDICAL PHYSICS. 2018;45(3):1210-1221

Quantitative evaluation of potential irradiation geometries for carbon-ion beam grid therapy.

Tsubouchi T; Henry T; Ureba A; Valdman A; Bassler N; Siegbahn A
Article: TECHNOLOGY IN CANCER RESEARCH & TREATMENT. 2017;16(6):749-757

Proton Grid Therapy: A Proof-of-Concept Study.

Henry T; Ureba A; Valdman A; Siegbahn A
Article: PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS. 2017;42:263-270

Comparative study of the calculated risk of radiation-induced cancer after photon- and proton-beam based radiosurgery of liver metastases.

Mondlane G; Gubanski M; Lind PA; Ureba A; Siegbahn A
Article: INTERNATIONAL JOURNAL OF PARTICLE THERAPY. 2016;3(2):277-284

Dosimetric Comparison of Plans for Photon- or Proton-Beam Based Radiosurgery of Liver Metastases.

Mondlane G; Gubanski M; Lind PA; Henry T; Ureba A; Siegbahn A
Article: PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS. 2015;31(6):568-583

Medical physics aspects of the synchrotron radiation therapies: Microbeam radiation therapy (MRT) and synchrotron stereotactic radiotherapy (SSRT).

Bräuer-Krisch E; Adam J-F; Alagoz E; Bartzsch S; Crosbie J; DeWagter C; Dipuglia A; Donzelli M; Doran S; Fournier P; Kalef-Ezra J; Kock A; Lerch M; McErlean C; Oelfke U; Olko P; Petasecca M; Povoli M; Rosenfeld A; Siegbahn EA; Sporea D; Stugu B
Article: JOURNAL OF SYNCHROTRON RADIATION. 2014;21(Pt 4):801-810

Spatial and temporal distribution of γH2AX fluorescence in human cell cultures following synchrotron-generated X-ray microbeams: lack of correlation between persistent γH2AX foci and apoptosis.

Anderson DL; Mirzayans R; Andrais B; Siegbahn EA; Fallone BG; Warkentin B
Article: JOURNAL OF INSTRUMENTATION. 2013;8:c06008

Comparison of two methods for measuring γ-H2AX nuclear fluorescence as a marker of DNA damage in cultured human cells: applications for microbeam radiation therapy

Anderson D; Andrais B; Mirzayans R; Siegbahn EA; Fallone BG; Warkentin B
Article: RADIOTHERAPY AND ONCOLOGY. 2013;106(1):106-111

Response of the rat spinal cord to X-ray microbeams.

Laissue JA; Bartzsch S; Blattmann H; Bräuer-Krisch E; Bravin A; Dalléry D; Djonov V; Hanson AL; Hopewell JW; Kaser-Hotz B; Keyriläinen J; Laissue PP; Miura M; Serduc R; Siegbahn AE; Slatkin DN
Article: JOURNAL OF SYNCHROTRON RADIATION. 2012;19(Pt 4):478-482

Chalcone JAI-51 improves efficacy of synchrotron microbeam radiation therapy of brain tumors.

Bouchet A; Boumendjel A; Khalil E; Serduc R; Bräuer E; Siegbahn EA; Laissue JA; Boutonnat J
Article: PHYSICS IN MEDICINE AND BIOLOGY. 2012;57(10):3223-3248

Evaluation of dose-volume metrics for microbeam radiation therapy dose distributions in head phantoms of various sizes using Monte Carlo simulations.

Anderson D; Siegbahn EA; Fallone BG; Serduc R; Warkentin B
Article: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2011;81(4):e439-e445

Delineation of gross tumor volume (GTV) for radiation treatment planning of locally advanced rectal cancer using information from MRI or FDG-PET/CT: a prospective study.

Brændengen M; Hansson K; Radu C; Siegbahn A; Jacobsson H; Glimelius B
Article: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT. 2011;629(1):345-349

In-line phase-contrast stereoscopic X-ray imaging for radiological purposes: An initial experimental study

Siegbahn EA; Coan P; Zhou S-A; Bravin A; Brahme A
Article: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2010;78(5):1503-1512

Preferential effect of synchrotron microbeam radiation therapy on intracerebral 9L gliosarcoma vascular networks.

Bouchet A; Lemasson B; Le Duc G; Maisin C; Bräuer-Krisch E; Siegbahn EA; Renaud L; Khalil E; Rémy C; Poillot C; Bravin A; Laissue JA; Barbier EL; Serduc R
Article: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2010;77(5):1545-1552

Tolerance of arteries to microplanar X-ray beams.

van der Sanden B; Bräuer-Krisch E; Siegbahn EA; Ricard C; Vial J-C; Laissue J
Article: PLOS ONE. 2010;5(2):e9028

High-precision radiosurgical dose delivery by interlaced microbeam arrays of high-flux low-energy synchrotron X-rays.

Serduc R; Bräuer-Krisch E; Siegbahn EA; Bouchet A; Pouyatos B; Carron R; Pannetier N; Renaud L; Berruyer G; Nemoz C; Brochard T; Rémy C; Barbier EL; Bravin A; Le Duc G; Depaulis A; Estève F; Laissue JA
Article: PHYSICS IN MEDICINE AND BIOLOGY. 2009;54(21):6711-6724

Synchrotron microbeam radiation therapy for rat brain tumor palliation-influence of the microbeam width at constant valley dose.

Serduc R; Bouchet A; Bräuer-Krisch E; Laissue JA; Spiga J; Sarun S; Bravin A; Fonta C; Renaud L; Boutonnat J; Siegbahn EA; Estève F; Le Duc G
Article: MEDICAL PHYSICS. 2009;36(4):1128-1137

MOSFET dosimetry with high spatial resolution in intense synchrotron-generated x-ray microbeams.

Siegbahn EA; Bräuer-Krisch E; Bravin A; Nettelbeck H; Lerch MLF; Rosenfeld AB
Article: PHYSICS IN MEDICINE AND BIOLOGY. 2008;53(5):1153-1166

Characterization and quantification of cerebral edema induced by synchrotron x-ray microbeam radiation therapy.

Serduc R; van de Looij Y; Francony G; Verdonck O; van der Sanden B; Laissue J; Farion R; Bräuer-Krisch E; Siegbahn EA; Bravin A; Prezado Y; Segebarth C; Rémy C; Lahrech H
Article: PHYSICS IN MEDICINE AND BIOLOGY. 2008;53(4):861-878

Irradiation of intracerebral 9L gliosarcoma by a single array of microplanar x-ray beams from a synchrotron: balance between curing and sparing.

Regnard P; Le Duc G; Bräuer-Krisch E; Troprès I; Siegbahn EA; Kusak A; Clair C; Bernard H; Dallery D; Laissue JA; Bravin A
Journal article: JOURNAL OF PHYSICS: CONFERENCE SERIES. 2008;102(1):012005

Monte Carlo code comparison of dose delivery prediction for microbeam radiation therapy

De Felici M; Siegbahn EA; Spiga J; Hanson AL; Felici R; Ferrero C; Tartari A; Gambaccini M; Keyriläinen J; Bräuer-Krisch E; Randaccio P; Bravin A
Article: MEDICAL PHYSICS. 2007;34(11):4322-4330

The GEANT4 toolkit for microdosimetry calculations: application to microbeam radiation therapy (MRT).

Spiga J; Siegbahn EA; Bräuer-Krisch E; Randaccio P; Bravin A
Article: MEDICAL PHYSICS. 2006;33(9):3248-3259

Determination of dosimetrical quantities used in microbeam radiation therapy (MRT) with Monte Carlo simulations.

Siegbahn EA; Stepanek J; Bräuer-Krisch E; Bravin A
Article: PHYSICS IN MEDICINE AND BIOLOGY. 2005;50(13):3103-3111

New irradiation geometry for microbeam radiation therapy.

Bräuer-Krisch E; Requardt H; Régnard P; Corde S; Siegbahn E; LeDuc G; Brochard T; Blattmann H; Laissue J; Bravin A
Article: REVIEW OF SCIENTIFIC INSTRUMENTS. 2005;76(6):064303

Characterization of a tungsten/gas multislit collimator for microbeam radiation therapy at the European Synchrotron Radiation Facility -: art. no. 064303

Bräuer-Krisch E; Bravin A; Zhang L; Siegbahn E; Stepanek J; Blattmann H; Slatkin DN; Gebbers JO; Jasmin M; Laissue JA
Article: PHYSICS IN MEDICINE AND BIOLOGY. 2003;48(10):1263-1275

Calculations of electron fluence correction factors using the Monte Carlo code PENELOPE.

Siegbahn EA; Nilsson B; Fernández-Varea JM; Andreo P
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All other publications

Conference publication: RADIOTHERAPY AND ONCOLOGY. 2022;170:S1255-S1256

Heart dose variability in RT of left breast cancer patients treated in deep inspiration breath hold

Johansson G; Freden E; Knutsson J; Olin M; Dagertun L; Siegbahn A
Conference publication: RADIOTHERAPY AND ONCOLOGY. 2021;161:S1513-S1514

Estimated risk of radiation-induced cancer after thymoma treatments with proton- or x-ray beams

Lidestahl A; Johansson G; Siegbahn A; Lind PA
Conference publication: RADIOTHERAPY AND ONCOLOGY. 2021;161:S1490-S1492

Evaluation of the setup accuracy of a surface scanning system in radiotherapy of breast cancer

Knutsson J; Johansson G; Dagertun L; Olin M; Siegbahn A
Conference publication: RADIOTHERAPY AND ONCOLOGY. 2018;127:S1202-S1203

dosimetric evaluation of carbon-ion beam grid therapy of brain tumors

Tsubouchi T; Valdman A; Siegbahn A
Conference publication: RADIOTHERAPY AND ONCOLOGY. 2018;127:S1092-S1093

Normal-tissue toxicity following gastric cancer radiotherapy with photon- or scanned proton-beams

Mondlane GA; Ureba A; Gubanski M; Lind P; Siegbahn A
Published conference paper: ACTA ONCOLOGICA. 2017;56(11):1437-1443

Development of an interlaced-crossfiring geometry for proton grid therapy.

Henry T; Bassler N; Ureba A; Tsubouchi T; Valdman A; Siegbahn A
Published conference paper: ACTA ONCOLOGICA. 2017;56(6):832-838

Comparison of gastric-cancer radiotherapy performed with volumetric modulated arc therapy or single-field uniform-dose proton therapy.

Mondlane G; Gubanski M; Lind PA; Ureba A; Siegbahn A
Conference publication: RADIOTHERAPY AND ONCOLOGY. 2017;123:S953

Proton grid therapy (PGT): a parameter study

Henry T; Valdman A; Siegbahn A
Conference publication: RADIOTHERAPY AND ONCOLOGY. 2017;123:S959

Evaluation of proton grid therapy in challenging clinical cases

Henry T; Valdman A; Siegbahn A
Conference publication: RADIOTHERAPY AND ONCOLOGY. 2016;119:S260

The development of proton-beam grid therapy (PBGT)

Henry T; Valdman A; Siegbahn A
Meeting abstract: MEDICAL PHYSICS. 2012;39(7Part4):4645

Sci-Sat AM: Brachy - 01: Evaluation of dose-volume metrics for microbeam radiation therapy.

Anderson D; Siegbahn EA; Fallone BG; Serduc R; Warkentin B
Letter: VETERINARY OPHTHALMOLOGY. 2012;15(3):210-211

A misprint in a description of microbeam irradiations of rats' heads.

Laissue JA; Blattmann H; Siegbahn EA; Slatkin DN
Conference publication: AIP CONFERENCE PROCEEDINGS. 2010;1266(1):89-97

Potential High Resolution Dosimeters For MRT

Bräuer-Krisch E; Rosenfeld A; Lerch M; Petasecca M; Akselrod M; Sykora J; Bartz J; Ptaszkiewicz M; Olko P; Berg A; Wieland M; Doran S; Brochard T; Kamlowski A; Cellere G; Paccagnella A; Siegbahn EA; Prezado Y; Martinez-Rovira I; Bravin A; Dusseau L; Berkvens P; Siu KKW
Published conference paper: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 2010;704(1-3):160-166

Effects of pulsed, spatially fractionated, microscopic synchrotron X-ray beams on normal and tumoral brain tissue.

Bräuer-Krisch E; Serduc R; Siegbahn EA; Le Duc G; Prezado Y; Bravin A; Blattmann H; Laissue JA
Conference publication: 2007;4:2571-2575

Geant4 Simulations for Microbeam Radiation Therapy (MRT) Dosimetry

Spiga J; Siegbahn EA; Bräuer-Krisch E; Randaccio P; Bravin A
Conference publication: 2006;3:1363-1367

Microdosimetry for Microbeam Radiation Therapy (MRT): theoretical calculations using the Monte Carlo toolkit

Spiga J; Siegbahn EA; Bräuer-Krisch E; Randaccio P; Bravin A
Corrigendum: REVIEW OF SCIENTIFIC INSTRUMENTS. 2006;77(3):039901

Characterization of a tungsten/gas multislit collimator (TMSC) for microbeam radiation therapy at the European Synchrotron Radiation Facility (vol 76, 064303, 2005) -: art. no. 039901

Bräuer-Krisch E; Bravin A; Zhang L; Siegbahn E; Stepanek J; Blattmann H; Slatkin DN; Gebbers JO; Jasmin M; Laissue JA
Published conference paper: IEEE TRANSACTIONS ON NUCLEAR SCIENCE. 2005;52(6):2562-2569

Edge-on face-to-face MOSFET for synchrotron microbeam dosimetry: MC modeling

Rosenfeld AB; Siegbahn EA; Brauer-Krish E; Holmes-Siedle A; Lerch MLF; Bravin A; Cornelius IM; Takacs GJ; Painuly N; Nettelback H; Kron T
Published conference paper: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT. 2005;548(1-2):69-71

Exploiting geometrical irradiation possibilities in MRT application

Bräuer-Krisch E; Requardt H; Régnard P; Corde S; Siegbahn EA; LeDuc G; Blattmann H; Laissue J; Bravin A
Published conference paper: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT. 2005;548(1-2):54-58

Dosimetric studies of microbeam radiation therapy (MRT) with Monte Carlo simulations

Siegbahn EA; Bräuer-Krisch E; Stepanek J; Blattmann H; Laissue JA; Bravin A

Employments

Affiliated to Research, Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, 2023-2026

Degrees and Education

Docent, Karolinska Institutet, 2021

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