Fibromyalgia patients have inflammation of the brain
Study. Using PET imaging, researchers at KI and Massachusetts General Hospital have shown that glial cells – the central nervous system’s immune cells – are activated in the brains of patients with the pain syndrome fibromyalgia. The finding has been published in the scientific journal Brain, Behavior, and Immunity and may open the way for new therapies.
New drug candidate makes cancer cells more sensitive to radiotherapy
Study. Researchers from Karolinska Institutet and Kancera AB have developed a molecule that makes cancer cells sensitive to radiotherapy. In a study published in Nature Communications, the researchers describe a new way to block cancer cells' ability to repair their DNA and thus stop the survival of cancer cells.
KI opens Biomedicum to the general public
Open house. On Saturday 29 September Karolinska Institutet invites the general public to an open house at the newly opened research laboratory Biomedicum on Campus Solna. Visitors will get a chance to meet researchers during lectures, exhibitions, interactive activities, scientific activities for children and more.
Use of muscle relaxant during general anaesthesia increases risk of pulmonary complications
Study. Muscle relaxants that are used during general anaesthesia increase the risk of pulmonary complications after surgery, according to a European multicentre study published in Lancet Respiratory Medicine, involving researchers at KI.
Structural map of bacterial toxins raises hopes for new anti-infectives
Study. The bacteria Pseudomonas aeruginosa can cause serious and difficult to treat infections. The infection process involves the activation of toxic substances from the bacteria by a common protein in our cells. Researchers at KI now show how this happens and that the activation can be stopped with drug-like molecules. The results are presented in Nature Communications.
Top publications in selection
A limited selection of recent publications in high impact journals where researchers from KI are main authors.
Genetic ”imbalance” linked to colorectal cancer
Contribution of allelic imbalance to colorectal cancer, Palin K et al, Nature Communications, September 2018.
Decision rule for treatment after coronary stenting shows questionable performance
External Validation of the DAPT Score in a Nationwide Population, Ueda P, Jernberg T, James S, Alfredsson J, Erlinge D, Omerovic E, Persson J, Ravn-Fischer A, Tornvall P, Svennblad B, Varenhorst C, JACC, August 2018.
Foster care in childhood increases risk of preterm delivery
Out-of-Home Care and Subsequent Preterm Delivery: An Intergenerational Cohort Study, Liu C, Vinnerljung B, Östberg V, Gauffin K, Juarez S, Cnattingius S, Hjern A, Pediatrics, August 2018.
KI in the media
Meet Professor Magnus Nilsson
Magnus Nilsson conducts research on better treatments against cancer of the oesophagus and of the stomach. His objectives: To develop more effective treatments, to save more lives, to make the treatments less invasive, and to contribute to the quality of life of the patient.