Lectures and seminars

Fysiologföreningen presents: Professor Anders Björklund

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2018-12-1714:30 Biomedicum Lecture Room 3 (A0325), Biomedicum, Solnavägen 9, entrance floorCampus SolnaBiomedicum

Reconstruction of brain circuitry using pluripotent stem cells


Professor Anders Björklund, Wallenberg Neuroscience Center, Lund University


Recent studies have shown that neural progenitors derived from pluripotent stem cells survive and differentiate after transplantation, and that they possess a remarkable capacity to extend axons over long distances and become functionally integrated into host neural circuitry.

Dr. Björklund will summarize these developments in the perspective of earlier studies using intracerebral and intraspinal transplants of primary neurons derived from fetal brain, with special focus on the ability of stem cell-derived progenitors to reconstruct damaged neural circuitry in cortex, hippocampus and the nigrostriatal system, and discuss the intrinsic and extrinsic factors that determine the growth properties of the grafted neurons and their capacity to reconstruct neural circuitry in the damaged host brain.


Christian Broberger

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Christian Broberger
-mail: Christian.Broberger@ki.se

Contact person: Christian Broberger