Susanne Schlisio awarded a 6 year senior research position from The Swedish Childhood Cancer Foundation
Susanne Schlisio (Pictured 2nd left with her research group) has been awarded a 6 year senior research position from The Swedish Childhood Cancer Foundation (Barncancerfonden) despite fierce competition - hers was one of only 26 approved applications.
Susanne Schlisio's research concerns the mechanisms of how disruption of oxygen-sensing pathways can lead to cancer. Oxygen sensors enable the cell to adapt to low-oxygen environments and are critical for normal development and apoptosis. These events are often disrupted in the development of tumors. Oxygen sensing is mediated partly via prolyl hydroxylases that require molecular oxygen for enzymatic activity. Our work focuses on how prolyl hydroxylases execute apoptosis in neural precursors during development and how disruption of this process can lead to certain forms of nervous-system tumors.