Immunology and Microbiology Seminar: Harnessing bacteria for drug discovery: from bioprospecting to synthetic biology

Speaker: Prof. Sergey B. Zotchev

Speaker Address: University of Vienna, Vienna, Austria

Host: Ute Römling

Selected reading:

Genome-based bioprospecting of microbes for new therapeutics.
Zotchev S, Sekurova O, Katz L
Curr. Opin. Biotechnol. 2012 Dec;23(6):941-7

Genomics of sponge-associated Streptomyces spp. closely related to Streptomyces albus J1074: insights into marine adaptation and secondary metabolite biosynthesis potential.
Ian E, Malko D, Sekurova O, Bredholt H, Rückert C, Borisova M, et al
PLoS ONE 2014 ;9(5):e96719

Engineering terpene biosynthesis in Streptomyces for production of the advanced biofuel precursor bisabolene.
Phelan R, Sekurova O, Keasling J, Zotchev S
ACS Synth Biol 2015 Apr;4(4):393-9

Minimum Information about a Biosynthetic Gene cluster.
Medema M, Kottmann R, Yilmaz P, Cummings M, Biggins J, Blin K, et al
Nat. Chem. Biol. 2015 Sep;11(9):625-31

Development of a Biosensor Concept to Detect the Production of Cluster-Specific Secondary Metabolites.
Sun Y, Busche T, Rückert C, Paulus C, Rebets Y, Novakova R, et al
ACS Synth Biol 2017 06;6(6):1026-1033