Sarcoidosis Epidemiology Research Group

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Who we are

Our research group in sarcoidosis epidemiology is part of the Chronic Inflammatory Diseases Epidemiology research section based at the Clinical Epidemiology Division, Department of Medicine Solna.


Associate Professor in Epidemiology

Elizabeth Arkema


PhD Student in Epidemiology

Marios Rossides



Our vision and mission

Our overarching goal is to better understand the causes and consequences of sarcoidosis.

Specifically, our aims are to:

  • Identify risk factors for sarcoidosis

  • Reduce the time from symptoms to diagnosis

  • Improve treatment strategies for sarcoidosis

  • Minimize the long-term consequences of sarcoidosis

Our mission is to provide evidence-based answers to etiological and clinical questions using epidemiological methods.


Our data

Sweden’s high quality and comprehensive healthcare data allow us to conduct large-scale investigations of risk factors for and outcomes after sarcoidosis. These nationwide data from health and demographic registers form the basis of our data repository for sarcoidosis research. It is further enriched by the inclusion of clinical and laboratory data for about 1500 individuals included in the sarcoidosis clinical cohort at Karolinska University Hospital.

Our work is supported by grants from the Swedish Research CouncilHjärt-Lungfonden, Svenska Läkaresällskapet, SFO Epidemiology, and Karolinska Institutet Research Foundation.



Our work brings together the expertise of clinicians, immunologists and epidemiologists. Collaborations are essential for the exchange of expertise from all scientific fields and we welcome researchers interested in sarcoidosis research to contact us.

Currently, we work closely with the following divisions:


Selected publications

Work ability before and after sarcoidosis diagnosis in Sweden.
Arkema E, Eklund A, Grunewald J, Bruze G
Respir Med 2018 Nov;144S():S7-S12

Epidemiology of sarcoidosis: current findings and future directions.
Arkema E, Cozier Y
Ther Adv Chronic Dis 2018 Nov;9(11):227-240

Familial aggregation and heritability of sarcoidosis: a Swedish nested case-control study.
Rossides M, Grunewald J, Eklund A, Kullberg S, Di Giuseppe D, Askling J, et al
Eur. Respir. J. 2018 08;52(2):

Sarcoidosis mortality in Sweden: a population-based cohort study.
Rossides M, Kullberg S, Askling J, Eklund A, Grunewald J, Arkema E
Eur. Respir. J. 2018 02;51(2):

Sarcoidosis incidence and prevalence: a nationwide register-based assessment in Sweden.
Arkema E, Grunewald J, Kullberg S, Eklund A, Askling J
Eur. Respir. J. 2016 12;48(6):1690-1699

Familial aggregation of rheumatoid arthritis in sarcoidosis: a register-based case-control study in Sweden.
Arkema E
Arthritis Rheumatol. 2016; 68(Suppl 10)


Written about our work...

Betydelsen av ärftlighet och miljöfaktorer (in Swedish).
Susanna Kullberg, Marios Rossides
SarkoidoseNytt. 2018;2

Ärftlighet påverkade risk för sarkoidos (in Swedish).
Susanna Kullberg, Marios Rossides
Läkartidningen. 2018;115:FACL

Sarcoidosis risk higher in families with disease history, study reports.
Vijaya Iyer 2018-07-19

Sarkoidos: epidemiologi, diagnostik och behandling (in Swedish).
Antje Kuhlmann
Lung & Allergiforum. 2017; 2

Västerbottningarna svårt drabbade av lungsjukdomen sarkoidos (in Swedish).
Anna Aderlund
Hjärt-Lungfonden. 2017

Oklart varför prevalensen av sarkoidos skiljer sig geografiskt (in Swedish).
Susanna Kullberg, Elizabeth Arkema
Läkartidningen. 2016;113:D7E6


Contact or visit us

You can reach us via the following channels:

Twitter @elizabetharkema
Post Karolinska Institutet
Department of Medicine Solna
Clinical Epidemiology Division, T2
171 76 Stockholm
Visit us Clinical Epidemiology Division
Eugeniahemmet, T2
Karolinska University Hospital
171 76 Stockholm
EpidemiologyInflammationPulmonary medicineRegister-based research