Immune mechanisms in atherosclerosis

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Previous studies have shown that activated immune cells play an important role at the development of atherosclerosis. Our aim is to develop new treatments for people with cardiovascular diseases caused by the immune system.

Professor, senior

Göran K Hansson

E-mail: Goran.Hansson@ki.se

 

Projects

NKT cells in atherosclerosis

Gabrielle Paulsson-Berne

Innate immunity in atherosclerosis

Zhong-Qun Yan

Molecular mechanisms in ischemic heart disease

Anders Gabrielsen

Cardiovascular Eicosanoid Research

Magnus Bäck

Cooperation

Ceric

Hjärt- och lungfonden

CMM

Vetenskapsrådet

Publications

Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis.
Hermansson A, Ketelhuth D, Strodthoff D, Wurm M, Hansson E, Nicoletti A, et al
J. Exp. Med. 2010 May;207(5):1081-93

Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease.
Folkersen L, van't Hooft F, Chernogubova E, Agardh H, Hansson G, Hedin U, et al
Circ Cardiovasc Genet 2010 Aug;3(4):365-73

Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis.
Klingenberg R, Lebens M, Hermansson A, Fredrikson G, Strodthoff D, Rudling M, et al
Arterioscler. Thromb. Vasc. Biol. 2010 May;30(5):946-52

Dendritic cells pulsed with malondialdehyde modified low density lipoprotein aggravate atherosclerosis in Apoe(-/-) mice.
Hjerpe C, Johansson D, Hermansson A, Hansson G, Zhou X
Atherosclerosis 2010 Apr;209(2):436-41

Innate immune signals in atherosclerosis.
Lundberg A, Hansson G
Clin. Immunol. 2010 Jan;134(1):5-24

Members

Hildur ArnardottirPostdoctoral researcher, Marie Curie
Roland BaumgartnerPostdoc
Martin BergGraduate Student
Gabrielle Paulsson-BerneSenior forskare
Magnus BäckProfessor
April CaravacaGraduate Student, Research assistant
Monica CentaPhD student
Michael EberhardsonAssociated
Maria Forteza de los ReyesPostdoc
Anders GabrielsenAssociated
Alessandro GallinaPhD student
Anton GisteråAssociated, Research assistant
Emilie GrassetPostdoc
Linda HaglundBiomedical scientist
Sanna HellbergPostdoc
Xintong JiangGraduate Student
Glykeria KaradimouGraduate Student, Research assistant
Daniel KetelhuthDocent
Stephen MalinAssistant professor, Senior researcher
Peder OlofssonSenior researcher
Anneli OlssonBiomedical scientist
Konstantinos PolyzosGraduate Student
Vladimir ShavvaPostdoc
Leif SöderströmAssociated
Laura TarnawskiPostdoc
Silke ThulPostdoc
Mohamad YounessAssociated
Yan Zhong-QunSenior researcher