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Arnér group - research focus and publications

Our research group has two main focuses: The Mammalian thioredoxin system in health and disease, and the development of selenoprotein production in E.coli.

The mammalian thioredoxin system.

Mammalian thioredoxin system

We are studying the role and function of selenoproteins. A main focus is on the mammalian thioredoxin system, predominantly the expression, regulation and function of the selenoprotein thioredoxin reductase 1 (TrxR1) and its splice variants.

Selenoprotein production in E.coli.

Selenoprotein production in E.coli

Another focus of research is the further development of general production systems for synthesis of heterologous selenoproteins in E. coli and their potential use for diverse biotechnological applications.