QRC Research Unit

Our vision is to contribute to better health care by facilitating that register holders, decision makers, researchers, pharmaceutical industry, and students regularly use quality register in their work, and that patients request this in health care settings.

QRC Stockholm supports quality registries regionally and nationally in the development of (among other things) operations, improvement work, research support and performance analysis, which in turn will ensure the quality of care. We are also continuously working on developing innovative processes together with register holder and their organizations.

We work mainly with register development, improvement work, partnership with patients, and research. The research conducted at the research unit at LIME, Karolinska Institutet, covers quality improvement and patient-reported outcome measures.

Research group leader

Acting Unit Manager QRC Stockholm Quality Register Center

Lillemor Bergström

Group members

Emelie Heintz

Affiliated to research


Patient-Reported Outcome Measures (PROMs)

EQ-5D Research Project

The Swedish Research Program of Mutual Interest (SRPMI) will be conducted in 2016-2021, according to the Sweden-EuroQol Research Foundation (ERF) agreement about the use of EQ-5D within the Swedish PROMs Program, a program which supports the use of patient-reported measures within the Swedish National Quality Registers (NQRs).

The focus of the program is the use of large-scale application of EQ-5D data from the Swedish NQRs and the Stockholm County Council health databases to inform decision-making in the Swedish health care system. The work within the program will be done in collaboration with the NQRs and/or other potential users of EQ-5D for decision-making in Sweden (county councils, the Dental and Pharmaceutical Benefits Agency, National Board of Health and Welfare etc.).


Emelie Heintz

QRC Coaching Academy

QRC Coaching Academy offers services for improvement work through courses and education programs. For more information

Improvement work supported by quality registers, 15 credits

The course is designed for those who want to pursue sustainable improvement work at a health care clinic, with the help of quality registers while learning and practicing coaching methods. The course is based on four core areas: improvement science, coaching and change management, quality registers and measurements, as well as patient collaboration and partnership.

Use of registers in clinical research

The course is arranged by QRC Stockholm, KI Södersjukhuset and KI Danderyd Hospital. The course is aimed at research-oriented health care professionals, graduate students, and professionals from pharmaceutical and medtech industry.

Research support

QRC Stockholm (QRC) is a Regional registry centre for National Quality Registries (NQR) and also forms a strategic cooperation between Karolinska Institutet (KI) and the Stockholm County Council. Vinnvård finances a half time postdoc position for Emelie Heintz during the period 2016-2019.


EuroQol Foundation

Health Economics and Economic Evaluation Research Group, LIME, Karolinska Institutet

Centrum för utvärdering av medicinsk teknologi (CMT), Avdelningen för hälso- och sjukvårdsanalys (HSA), Linköpings universitet


Collection and use of EQ-5D for follow-up, decision-making, and quality improvement in health care - the case of the Swedish National Quality Registries.
Ernstsson O, Janssen MF, Heintz E
2020 Sep;4(1):78

Electroconvulsive Therapy in Depression: Improvement in Quality of Life Depending on Age and Sex.
Güney P, Ekman CJ, Hammar Å, Heintz E, Landén M, Lundberg J, et al
J ECT 2020 Feb;():

Whom should we ask? A systematic literature review of the arguments regarding the most accurate source of information for valuation of health states.
Helgesson G, Ernstsson O, Åström M, Burström K
Qual Life Res 2020 Feb;():

Determinants of quality of life in pediatric- and adult-onset multiple sclerosis.
McKay KA, Ernstsson O, Manouchehrinia A, Olsson T, Hillert J
Neurology 15 November 2019; pii: 10.1212/WNL.0000000000008667

Influence of elicitation procedure and phrasing on health state valuations in experience-based time trade-off tasks among diabetes patients in China.
Hao S, Heintz E, Helgesson G, Langenskiöld S, Chen J, Burström K
Qual Life Res 2019 Sep;():

Short-term Resource Utilization and Cost-Effectiveness of Comprehensive Geriatric Assessment in Acute Hospital Care for Severely Frail Elderly Patients.
Ekerstad N, Karlson BW, Andersson D, Husberg M, Carlsson P, Heintz E, et al
J Am Med Dir Assoc 2018 10;19(10):871-878.e2

Ethical aspects of diagnosis and interventions for children with fetal alcohol Spectrum disorder (FASD) and their families.
Helgesson G, Bertilsson G, Domeij H, Fahlström G, Heintz E, Hjern A, et al
BMC Med Ethics 2018 01;19(1):1

Is the acute care of frail elderly patients in a comprehensive geriatric assessment unit superior to conventional acute medical care?
Ekerstad N, Karlson BW, Dahlin Ivanoff S, Landahl S, Andersson D, Heintz E, et al
Clin Interv Aging 2017 ;12():1-9

Boosting Quality Registries with Clinical Decision Support Functionality*. User Acceptance of a Prototype Applied to HIV/TB Drug Therapy.
Wannheden C, Hvitfeldt-Forsberg H, Eftimovska E, Westling K, Ellenius J
Methods Inf Med 2017 Aug;56(4):339-343

Creating a culture of health: evolving healthcare systems and patient engagement.
Lindblad S, Ernestam S, Van Citters AD, Lind C, Morgan TS, Nelson EC
QJM 2017 Mar;110(3):125-129

The External Validity of Mapping MSIS-29 on EQ-5D Among Individuals With Multiple Sclerosis in Sweden.
Ernstsson O, Tinghög P, Alexanderson K, Hillert J, Burström K
MDM Policy Pract ;2(1):2381468317692806

The Swedish RAND-36 Health Survey - reliability and responsiveness assessed in patient populations using Svensson's method for paired ordinal data.
Orwelius L, Nilsson M, Nilsson E, Wenemark M, Walfridsson U, Lundström M, et al
J Patient Rep Outcomes 2017 ;2(1):4

Patient focused registries can improve health, care, and science.
Nelson EC, Dixon-Woods M, Batalden PB, Homa K, Van Citters AD, Morgan TS, et al
BMJ 2016 Jul;354():i3319

Continuous innovation: developing and using a clinical database with new technology for patient-centred care--the case of the Swedish quality register for arthritis.
Ovretveit J, Keller C, Hvitfeldt Forsberg H, Essén A, Lindblad S, Brommels M
Int J Qual Health Care 2013 Apr;25(2):118-24


Värderingssystem för EQ-5D-5L, Raport 2018-04-12 (in Swedish)