Orthopedics and Traumatology

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Sari Ponzers research group in orthopaedics and traumatology focuses on osteoporosis related fractures and psychosocial factors affecting outcome after injuries. During the last years they have broadened their research area and have continually carried out clinical and epidemiological studies also on other types of injuries/diseases of the musculoskeletal system.

Research Projects

Hip fractures

Patients with hip fractures are elderly and have often severe osteoporosis. The research group is currently running three randomized trials comparing various fixation techniques of the prosthesis among elderly patients with femoral neck fractures.

More information: Anders Enocson, MD, PhD, Ass. professor, Christian Inngul, MD, PhD, Richard Blomfeldt, MD, PhD, Sari Ponzer, MD, PhD, Professor, Leif Mattison, MD, PhD student

Wrist fractures

Wrist fractures are common and the treatment is controversial. The interpretation of the outcome of the various treatment procedures is complicated by the wide range of patient expectation, from the young and active to the sedentary and non-active patient.

The research group is running three randomized trials to compare different fixation techniques and different anesthetic methods. The patients are followed, evaluated and compared utilizing modern Health-Related Quality of Life (HRQOL) instruments together with clinical outcome measures.

More information: Cecilia Mellstrand-Navarro, MD, PhD, Anders Enocson, MD, PhD, Ass. professor, Sari Ponzer, MD, PhD, Professor, Jenny Saving MD, PhD student, Johanna Rundgren, MD, PhD student

Recovery after whiplash injuries of the neck

The connection between genetic factors, environmental factors and the risk of non-recovery after trauma is poorly investigated nor understood. In a study on a patient cohort with traffic accidents, the research group investigates the relationship between different factors associated with recovery after injuries. The aims are to identify people with acute whiplash injuries who are at risk for non-recovery and to study in a RCT whether an intervention in the form of an information film can result in better recovery and reduced sick leave.

More information: Eric Rydman, MD, PhD student, Sari Ponzer, MD, PhD, Professor, Carin Ottosson, MD, PhD, Hans Järnbert-Pettersson, PhD

Deep infections after surgery and Vacuum Assisted Closure (VAC)

Deep infection is one of the most devastating and costly complications after surgery. Vacuum Assisted Closure (VAC) is a new and costly method. In on-going studies the research group aim to investigate the results of VAC method regarding patient selection, risk factors, treatment compliance and outcomes seen from the patient point of view.

More information: Ann-Mari Fagerdahl, RN, PhD, Carin Ottosson MD, PhD, Piotr Kasina, MD, PhD student

Lumbar intervertebral disc herniation

Low back pain is a common condition. It is not clear whether patients benefit from surgery. The existing evidence suggests that mechanical factors, inflammatory processes, as well as psychosocial patient related factors like background, social environment and pain coping together affects the outcome.

In a large prospective cohort study patients have been investigated thoroughly with the aim to find predictors to avoid unnecessary surgery.

More information: Peter Elkan, MD, PhD student, Sari Ponzer, MD, PhD, Professor

Anterior cruciate ligament (ACL) reconstruction

ACL injury is a common sports related injury where the patient will experience instability of the knee joint which may prevent sporting activities. ACL construction is a common procedure to remedy this.

The research group runs several studies focusing on the methods and timing of ACL reconstruction as well on osteoarthritis following ACL-reconstruction.

More information: Björn Barenius, MD, PhD, Karl Eriksson, MD, PhD, Ass. professor, Sari Ponzer, MD, PhD, Professor

Research Group


Björn Barenius

Katarina Bilén

Richard Blomfeldt

Anders Enocson

Karl Eriksson

Ann-Mari Fagerdahl

Christian Inngul

Lasse Lapidus

Cecilia Mellstrand-Navarro

Nathalie Mobargha

Charlotta Olivecrona

Carin Ottosson

Pierre Rotzius

Sari Ponzer

PhD students

Peter Elkan

Leif Mattison

Piotr Kasina

Johanna Rundgren

Eric Rydman

Jenny Saving 

Research Nurses

Catharina (Tina) Levander

Elisabeth Skogman 

Selected Publications

Markers of inflammation and fibrinolysis in relation to outcome after surgery for lumbar disc herniation. A prospective study on 177 patients.
Elkan P, Sten-Linder M, Hedlund R, Willers U, Ponzer S, Gerdhem P
Eur Spine J 2016 Jan;25(1):186-91

The operative treatment of fractures of the distal radius is increasing: results from a nationwide Swedish study.
Mellstrand-Navarro C, Pettersson H, Tornqvist H, Ponzer S
Bone Joint J 2014 Jul;96-B(7):963-9

Increased risk of osteoarthritis after anterior cruciate ligament reconstruction: a 14-year follow-up study of a randomized controlled trial.
Barenius B, Ponzer S, Shalabi A, Bujak R, Norlén L, Eriksson K
Am J Sports Med 2014 May;42(5):1049-57

Can early follow-up after deliberate self-harm reduce repetition? A prospective study of 325 patients.
Bilén K, Pettersson H, Owe-Larsson B, Ekdahl K, Ottosson C, Castrén M, et al
J Affect Disord 2014 Jan;152-154():320-5

Unipolar hemiarthroplasty versus bipolar hemiarthroplasty in patients with displaced femoral neck fractures: a four-year follow-up of a randomised controlled trial.
Inngul C, Hedbeck C, Blomfeldt R, Lapidus G, Ponzer S, Enocson A
Int Orthop 2013 Dec;37(12):2457-64

Symptomatic venous thromboembolism and mortality in orthopaedic surgery - an observational study of 45 968 consecutive procedures.
Lapidus L, Ponzer S, Pettersson H, de Bri E
BMC Musculoskelet Disord 2013 Jun;14():177