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WOLF (Work, Lipids and Fibrinogen)

The aim of the WOLF-project is to study whether psychosocial work environment conditions influence the risk of developing hypertension, different lipid disturbances or increased levels of fibrinogen.

The substantial differences in incidence of myocardial infarction that have been observed among different occupational groups, as well as among different socio-economic groups are probably not totally explained by differences in lifestyle and living conditions.


All employees from different companies or parts of companies were invited to participate in the project. Base line data from about 10.000 working men and women in the Stockholm area and from northern Sweden have been collected. The study population will be followed with regard to cardiovascular risk factors as well as incidence of myocardial infarction.


The study is carried out as a multicenter study between different research institutions and occupational health care centers. Collaborating research institutions are Department of Public Health Sciences at Karolinska Institutet, National Institute of Psychosocial Factors and Health, Sweden, National Institute for Working Life, Sweden, Department of Occupational and Environmental Medicine at University of Umeå, Department of Medical Sociology, Heinrich Heine Universität, Germany, and Department or Medical Sociology, University of Ulm, Germany.


  • Vetenskapsrådet
  • Försäkringsbolaget AFA
  • Forskningsrådet för arbetsliv och socialvetenskap


Professor Lars Alfredsson, Principal investigator

Work: +46 8 524 87 488