Inflammatory markers and coronary heart disease
During the latest decades several studies have observed a relationship between particulate urban air pollutants and increased occurrence of coronary heart disease. Inhalation of air pollutants may generate a low-grade inflammation which increases the coagulation of the blood and in the long run increases the risk of atherosclerosis. Within this area we study occupational exposure to air pollutants and the occurrence of coronary heart disease. We also investigate exposure to air pollutants (in experimental and field studies) and its relationship to inflammatory markers. Some of the inflammatory markers are fibrinogen and C-reactive protein (CRP) which are established risk factors of coronary heart disease.
Parts of these studies were supported by FORTE (the Swedish Research Council for Health, Working Life and Welfare).