Exposure to endocrine disrupting chemicals in early childhood and health effects in childhood and adolescence
Chemicals present in our close environment, such as phthalates, bisphenol A, and triclosan are suspected endocrine disrupting chemicals (EDCs) found in traceable levels in humans. Despite many years of research there is no firm evidence that low level environmental exposures to such chemicals can play a role in increasing prevalence of obesity, earlier onset of puberty and allergy-related diseases among children. The aim of this project is to investigate the role of early childhood exposure to EDCs for pubertal development, obesity and allergy-related diseases (asthma, rhinitis, eczema and sensitization to airborne and food allergens) in later childhood and adolescence. The study benefits from the on-going population-based longitudinal birth cohort (BAMSE) and is based on previous findings in the cohort, taking advantage of the extensive cohort database and investments already made in this material. The results will add important information on the development of allergy-related diseases in the population, as well as information about the role of EDCs in pubertal development and obesity, a research field with pressing need for more knowledge.
This study is performed in collaboration with IMM, units of Biochemical toxicology and Environmental medicine, Lund University, Stockholm University, and IVL Swedish Environmental Research Institute.
- Swedish Environmental Protection Agency