Temporomandibular joint pathology and surgery

Internal derangement of the temporomandibular joint (TMJ), defined as displacement of the disc in relation to the condylar head and articular eminence are common, with a strong, as yet unexplained, female predominance.

Aetiology of internal derangement is unknown although trauma and local- or general joint hypermobility have been discussed as possible predisposing factors. When eventual non-surgical treatment has failed, TMJ surgical treatment may be performed. The primary surgical treatments are arthroscopy or discectomy, depending on the diagnosis. The success-rate is about 85% and it is apparent that the post-operative condition does not deteriorate with time. As yet, the group not responding to this treatment is largely uncharacterised. Consequently, predictors for which cases are likely to succeed or fail are still lacking.

Principal Investigator

Project: Tissue- and clinical characteristics of internal derangement of the temporomandibular joint

The project aims at improving the understanding of the pathophysiology of internal derangement and to develop tissue-based diagnostic- and treatment criteria for patients with internal derangements of the TMJ, and to identify factors that may predict a non-successful outcome of surgical therapy.


  • Bodil Lund, PhD, Associate professor, Consultant in Oral and maxillofacial Surgery
  • Carina Kruger Weiner, PhD, Assistant professor, Consultant in Oral and maxillofacial Surgery
  • Mattias Ulmner, PhD-student, Consultant in Oral and maxillofacial Surgery
  • Rachael Sugars, Associate professor, Cell- and molecular biologist specialized in oral biochemistry and biology