Xiaowei Gong

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Article: MOLECULAR SYSTEMS BIOLOGY. 2023;19(6):e11490

Multisite assessment of reproducibility in high-content cell migration imaging data.

Hu J; Serra-Picamal X; Bakker G-J; Van Troys M; Winograd-Katz S; Ege N; Gong X; Didan Y; Grosheva I; Polansky O; Bakkali K; Van Hamme E; van Erp M; Vullings M; Weiss F; Clucas J; Dowbaj AM; Sahai E; Ampe C; Geiger B; Friedl P; Bottai M; Strömblad S
Article: SCIENCE ADVANCES. 2022;8(12):eabl3667

Local temporal Rac1-GTP nadirs and peaks restrict cell protrusions and retractions.

Hu J; Gong X; Strömblad S
Article: NATURE COMMUNICATIONS. 2019;10(1):3589

PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer.

Costa TDF; Zhuang T; Lorent J; Turco E; Olofsson H; Masia-Balague M; Zhao M; Rabieifar P; Robertson N; Kuiper R; Sjölund J; Spiess M; Hernández-Varas P; Rabenhorst U; Roswall P; Ma R; Gong X; Hartman J; Pietras K; Adams PD; Defilippi P; Strömblad S
Article: NATURE CELL BIOLOGY. 2018;20(11):1290-1302

Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis.

Lock JG; Jones MC; Askari JA; Gong X; Oddone A; Olofsson H; Göransson S; Lakadamyali M; Humphries MJ; Strömblad S
Article: EMBO JOURNAL. 2018;37(17):e98994

KIF13A-regulated RhoB plasma membrane localization governs membrane blebbing and blebby amoeboid cell migration.

Gong X; Didan Y; Lock JG; Strömblad S
Article: ELIFE. 2016;5:e11384

An analysis toolbox to explore mesenchymal migration heterogeneity reveals adaptive switching between distinct modes.

Shafqat-Abbasi H; Kowalewski JM; Kiss A; Gong X; Hernandez-Varas P; Berge U; Jafari-Mamaghani M; Lock JG; Strömblad S
Article: AMERICAN JOURNAL OF CHINESE MEDICINE. 2016;44(5):1027-1041

Pinellia ternata Attenuates Mucus Secretion and Airway Inflammation after Inhaled Corticosteroid Withdrawal in COPD Rats.

Du W; Su J; Ye D; Wang Y; Huang Q; Gong X
Article: INTEGRATIVE BIOLOGY. 2015;7(10):1171-1185

Non-monotonic cellular responses to heterogeneity in talin protein expression-level.

Kiss A; Gong X; Kowalewski JM; Shafqat-Abbasi H; Strömblad S; Lock JG
Article: PLOS ONE. 2015;10(8):e0135204

Disentangling Membrane Dynamics and Cell Migration; Differential Influences of F-actin and Cell-Matrix Adhesions.

Kowalewski JM; Shafqat-Abbasi H; Jafari-Mamaghani M; Endrias Ganebo B; Gong X; Strömblad S; Lock JG
Article: CELL METABOLISM. 2014;19(6):981-992

Early B cell factor 1 regulates adipocyte morphology and lipolysis in white adipose tissue.

Gao H; Mejhert N; Fretz JA; Arner E; Lorente-Cebrián S; Ehrlund A; Dahlman-Wright K; Gong X; Strömblad S; Douagi I; Laurencikiene J; Dahlman I; Daub CO; Rydén M; Horowitz MC; Arner P
Article: PLOS ONE. 2014;9(2):e90593

Plasticity in the macromolecular-scale causal networks of cell migration.

Lock JG; Mamaghani MJ; Shafqat-Abbasi H; Gong X; Tyrcha J; Strömblad S
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;425(2):357-362

Stress-induced interaction between p38 MAPK and HSP70.

Gong X; Luo T; Deng P; Liu Z; Xiu J; Shi H; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO = JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2012;32(8):1148-1150

[A novel method for studying nuclear localization signal-mediated nuclear translocation].

Deng P; Gong X; Jiang Y
Article: PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. 2011;37(12):1265-1270

Progresses in The Studies on Kindlin Family Members

Xiong Y; Gong X-W; Jiang Y
Article: CANCER LETTERS. 2010;299(1):54-62

Kindlin-2 controls sensitivity of prostate cancer cells to cisplatin-induced cell death.

Gong X; An Z; Wang Y; Guan L; Fang W; Strömblad S; Jiang Y; Zhang H
Article: FEBS LETTERS. 2010;584(23):4711-4716

UV-induced interaction between p38 MAPK and p53 serves as a molecular switch in determining cell fate.

Gong X; Liu A; Ming X; Deng P; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO = JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2010;30(10):2310-2313

[Construction of pNTAP-MK2 eukaryotic expression plasmid and establishment of a cell line for its stable expression].

Wang D-A; Gong X-W; Liu A-H; Mei Z-Z; Wang D; Ming X-Y; Wang X; Wei J; Deng P; Jiang Y
Article: JOURNAL OF CELLULAR BIOCHEMISTRY. 2010;110(6):1420-1429

Mechanisms regulating the nuclear translocation of p38 MAP kinase.

Gong X; Ming X; Deng P; Jiang Y
Journal article: FRONTIERS OF MEDICINE. 2010;4(1):46-53

Mitogen-activated protein kinase pathway inhibitors: inhibitors for diseases?

Wang X; Gong X-W; Li Y-H; Jiang Y
Journal article: FRONTIERS OF MEDICINE. 2009;3(4):379-383

Effect of PRAK gene knockout on the proliferation of mouse embryonic fibroblasts

Gong X; Liu A; Ming X; Wang X; Wang D; Deng P; Jiang Y
Article: FEBS JOURNAL. 2009;276(16):4598-4606

Advanced glycation end products and lipopolysaccharide synergistically stimulate proinflammatory cytokine/chemokine production in endothelial cells via activation of both mitogen-activated protein kinases and nuclear factor-kappaB.

Liu J; Zhao S; Tang J; Li Z; Zhong T; Liu Y; Chen D; Zhao M; Li Y; Gong X; Deng P; Wang JH; Jiang Y
Article: GLYCOCONJUGATE JOURNAL. 2009;26(2):173-188

Lactosyl derivatives function in a rat model of severe burn shock by acting as antagonists against CD11b of integrin on leukocytes.

Zhao Z; Li Q; Hu J; Li Z; Liu J; Liu A; Deng P; Zhang L; Gong X; Zhao K; Zhang S; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO = JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2008;28(10):1779-1781

[Construction of different mutants of HA-tagged human RAGE gene and their eukaryotic expression].

Cheng W-W; Li Y-S; Gong X-W; Zhao L-L; Wang J-G; Deng P; Jiang Y
Article: ZHONGGUO WEI ZHONG BING JI JIU YI XUE. 2008;20(9):527-529

[Effect of p38 mitogen-activated protein kinase gene knockout on cell proliferation of embryonic fibroblasts in mice].

Gong X-W; Wei J; Li Y-S; Cheng W-W; Deng P; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO = JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2008;28(5):671-674

[Construction and expression of different mutants of human p53 and their effects on arsenite-induced cell apoptosis].

Liu A-H; Gong X-W; Wei J; Ming X-Y; Wang D-A; Deng P; Luo S-Q; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO = JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2007;27(8):1132-1135

[Effect of p53 gene knockout on cell migration].

Gong X-W; Wei J; Li Y-S; Cheng W-W; Wang X; Deng P; Jiang Y
Article: NAN FANG YI KE DA XUE XUE BAO = JOURNAL OF SOUTHERN MEDICAL UNIVERSITY. 2007;27(7):983-986

[Construction and expression of the fusion vector for HA-tagged human RAGE gene].

Li Y-S; Gong X-W; Cheng W-W; Wei J; Jiang Y
Journal article: FRONTIERS OF MEDICINE IN CHINA. 2007;1(3):248-252

Involvement of p38 mitogen-activated protein kinase in the regulation of platelet-derived growth factor -induced cell migration.

Gong X; Wei J; Li Y; Cheng W; Deng P; Jiang Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2005;25(6):619-622

[Effect of Liangge San on lipopolysaccharide-induced nuclear factor kappa B activation in cultured mouse macrophages].

Jiang A-D; Yu L-Z; Gong X-W; Deng P; Ma X-D
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2005;25(3):285-288

[Construction and expression of green fluorescent protein fusion vector of p38 regulated/activated protein kinase].

Peng Y; Gong X-W; Deng P; Qin Q-H; Jiang Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2004;24(6):628-635

[Construction and expression of the fusion vector of His-tagged human ARPC2 gene].

Gong X-W; Peng Y; Liu J-H; Li Z-J; Deng P; Qin Q-H; Jiang Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2004;24(2):139-143

Killing effect of suicide gene system under control by KDR promotor on human umbilical vein endothelial cells.

Huang Z-H; Yang W-Y; Gong X-W; Qian Y; Che X-Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2003;23(11):1131-1133

[Screening and identification of proteins interacting with p38 MAP kinase via T7 phage-display screening system].

Li Z-J; Liu J-H; Gong X-W; Qin Q-H; Huang H; Deng P; Wang J-Z; Zhao S-C; Sun X-G; Liu Y-W; Zhao K-S; Jiang Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2003;23(3):206-209

Regulation of inducible nitricoxide synthase gene transcription by p38 mitogen-activated protein kinase in human embryonic kidney 293 cells.

Guo A-H; Gong X-W; Kan W-H; Qin Q-H; Deng P; Wang J-Z; Jiang Y
Article: ZHONGGUO WEI ZHONG BING JI JIU YI XUE. 2003;15(3):163-166

[Construction of vector of his-tagged cytoplasmic fragment of human toll like receptor 4 and its expression in E.coli].

Liu J-H; Sun X-G; Li Z-J; Qin Q-H; Gong X-W; Deng P; Liu Y-W; Wang J-Z; Zhao K-S; Jiang Y
Article: PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. 2003;30(4):509-513

Mechanisms of the subcellular localization and stimuli-induced translocation of MAP kinases

Gong XW; Jiang Y
Article: DI YI JUN YI DA XUE XUE BAO = ACADEMIC JOURNAL OF THE FIRST MEDICAL COLLEGE OF PLA. 2002;22(2):171-173

[Construction and expression of red fluorescent protein fusion vector incorporating p38 mitogen-activated protein kinase].

Gong X-W; Qin Q-H; Wang J-Z; Jiang Y
Article: PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. 2001;28(3):299-303

The role of TLR4 in response to LPS in mammals

Gong XW; Jiang Y
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Alla övriga publikationer

Preprint: BIORXIV. 2022

Multi-site assessment of reproducibility in high-content live cell imaging data

Hu J; Serra-Picamal X; Bakker G-J; Van Troys M; Winograd-katz S; Ege N; Gong X; Didan Y; Grosheva I; Polansky O; Bakkali K; Van Hamme E; Van Erp M; Vullings M; Weiss F; Clucas J; Dowbaj AM; Sahai E; Ampe C; Geiger B; Friedl P; Bottai M; Strömblad S
Preprint: BIORXIV. 2021

Local temporal Rac1-GTP nadirs and peaks restrict cell protrusions and retractions

Hu J; Gong X; Strömblad S
Preprint: BIORXIV. 2017

Reticular adhesions: A new class of adhesion complex that mediates cell-matrix attachment during mitosis

Lock J; Jones M; Askari J; Gong X; Oddone A; Olofsson H; Göransson S; Lakadamyali M; Humphries M; Strömblad S
Review: PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS. 2007;34(7):695-701

Progresses in mitogen-activated protein kinase-activated protein kinases

Gong X-W; Jiang Y
Review: SHENG LI KE XUE JIN ZHAN [PROGRESS IN PHYSIOLOGY]. 2004;35(4):306-310

[Structure, function and modulation of actin-related protein 2/3 complex].

Gong X-W; Jiang Y

Forskningsbidrag

The role of Kindlin-2 and Prdx4 in inflammation-induced tumors and its mechanism

National Natural Science Foundation of China

1 January 2012 - 31 December 2015
Multiparametric analyses of the effects of targeted gene knockdown on cell motility and CMAC organisation

Karolinska Institutet Research Foundation

1 January 2012 - 31 December 2012
Cell stress-induced nuclear translocation of p38 MAPK molecular mechanism

National Natural Science Foundation of China

1 January 2008 - 31 December 2010
Identification of the interaction domains between ARPC2 and PRAK.

Medical Science and Technology Foundation of Guangdong Province, China

1 January 2006 - 31 December 2007

Anställningar

Forskare, Medicin, Huddinge, Karolinska Institutet, 2024-
Forskare, Biovetenskaper och näringslära, Karolinska Institutet, 2011-2024
Associate professor, Pathophysiology, Southern Medical University, 2008-2015
Lecturer, Pathophysiology, Southern Medical University, 2004-2007
Lecturer, Pathophysiology, The First Military Medical University, 2004-2004
Teaching assistant, Pathophysiology, The First Military Medical University, 2001-2004

Examina och utbildning

PhD, MD, The First Military Medical University, 2004
Master degree in Pathophysiology, The First Military Medical University, 2001
Bachelor degree in Clinical Medicine, Clinical Medicine, The First Military Medical University, 1998

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