Sofia Berglund

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

I am a medical doctor and researcher interested in immunology, stem cell
transplantation, hematology and cancer.
MD, Medical Degree 2008 at KI, Medical License 2012.
PhD at KI 2014.

Forskningsbeskrivning

I work with translational research associated with the development of an
autologous T cell immunotherapy for solid cancer based on neoantigen
technology. Currently, my team is planning a clinical first-in-human trial of
our T cell product, pTTL, starting during 2022.

Artiklar

Article: VOX SANGUINIS. 2019;114(7):769-777

Granulocyte transfusions could benefit patients with severe oral mucositis after allogeneic hematopoietic stem cell transplantation.

Berglund S; Watz E; Remberger M; Garming Legert K; Axdorph-Nygell U; Sundin M; Uhlin M; Mattsson J
Article: JCI INSIGHT. 2018;3(21):120974

Signatures of CD8+ T cell dysfunction in AML patients and their reversibility with response to chemotherapy.

Knaus HA; Berglund S; Hackl H; Blackford AL; Zeidner JF; Montiel-Esparza R; Mukhopadhyay R; Vanura K; Blazar BR; Karp JE; Luznik L; Gojo I
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2018;194(1):39-53

Tissue-resident memory T cells are epigenetically cytotoxic with signs of exhaustion in human urinary bladder cancer.

Hartana CA; Ahlén Bergman E; Broomé A; Berglund S; Johansson M; Alamdari F; Jakubczyk T; Huge Y; Aljabery F; Palmqvist K; Holmström B; Glise H; Riklund K; Sherif A; Winqvist O
Article: CLINICAL EPIGENETICS. 2018;10(1):102

Increased CD4+ T cell lineage commitment determined by CpG methylation correlates with better prognosis in urinary bladder cancer patients.

Ahlén Bergman E; Hartana CA; Johansson M; Linton LB; Berglund S; Hyllienmark M; Lundgren C; Holmström B; Palmqvist K; Hansson J; Alamdari F; Huge Y; Aljabery F; Riklund K; Winerdal ME; Krantz D; Zirakzadeh AA; Marits P; Sjöholm LK; Sherif A; Winqvist O
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2018;24(4):666-677

Increased Coexpression of PD-1, TIGIT, and KLRG-1 on Tumor-Reactive CD8+ T Cells During Relapse after Allogeneic Stem Cell Transplantation.

Hutten TJA; Norde WJ; Woestenenk R; Wang RC; Maas F; Kester M; Falkenburg JHF; Berglund S; Luznik L; Jansen JH; Schaap N; Dolstra H; Hobo W
Article: BLOOD. 2018;131(2):247-262

NK cell recovery after haploidentical HSCT with posttransplant cyclophosphamide: dynamics and clinical implications.

Russo A; Oliveira G; Berglund S; Greco R; Gambacorta V; Cieri N; Toffalori C; Zito L; Lorentino F; Piemontese S; Morelli M; Giglio F; Assanelli A; Stanghellini MTL; Bonini C; Peccatori J; Ciceri F; Luznik L; Vago L
Article: STEM CELLS INTERNATIONAL. 2018;2018:8529104-15

Expansion of Gammadelta T Cells from Cord Blood: A Therapeutical Possibility.

Berglund S; Gaballa A; Sawaisorn P; Sundberg B; Uhlin M
Article: CYTOTHERAPY. 2014;16(11):1528-1536

Expanded umbilical cord blood T cells used as donor lymphocyte infusions after umbilical cord blood transplantation.

Berglund S; Gertow J; Uhlin M; Mattsson J
Article: JOURNAL OF IMMUNOTHERAPY. 2013;36(8):432-441

Cord blood T cells cultured with IL-7 in addition to IL-2 exhibit a higher degree of polyfunctionality and superior proliferation potential.

Berglund S; Gertow J; Magalhaes I; Mattsson J; Uhlin M
Article: CHIMERISM. 2013;4(1):34-35

Chimerism and use of mesenchymal stem cells in umbilical cord blood transplantation.

Berglund S; Uhlin M; Mattsson J
Article: TRANSPLANTATION. 2012;94(10):1066-1074

Factors with an impact on chimerism development and long-term survival after umbilical cord blood transplantation.

Berglund S; Le Blanc K; Remberger M; Gertow J; Uzunel M; Svenberg P; Winiarski J; Ljungman P; Ringdén O; Uhlin M; Mattsson J
Article: CLINICAL INFECTIOUS DISEASES. 2012;55(8):1064-1073

Rapid salvage treatment with virus-specific T cells for therapy-resistant disease.

Uhlin M; Gertow J; Uzunel M; Okas M; Berglund S; Watz E; Brune M; Ljungman P; Maeurer M; Mattsson J
Article: STEM CELLS AND DEVELOPMENT. 2012;21(9):1409-1417

Mesenchymal stem cells inhibit thymic reconstitution after allogeneic cord blood transplantation.

Uhlin M; Sairafi D; Berglund S; Thunberg S; Gertow J; Ringden O; Uzunel M; Remberger M; Mattsson J
Article: CLINICAL IMMUNOLOGY. 2012;143(2):134-144

Expansion of T-cells from the cord blood graft as a predictive tool for complications and outcome of cord blood transplantation.

Gertow J; Berglund S; Okas M; Kärre K; Remberger M; Mattsson J; Uhlin M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(11):1688-1697

Improved survival after allogeneic hematopoietic stem cell transplantation in recent years. A single-center study.

Remberger M; Ackefors M; Berglund S; Blennow O; Dahllöf G; Dlugosz A; Garming-Legert K; Gertow J; Gustafsson B; Hassan M; Hassan Z; Hauzenberger D; Hägglund H; Karlsson H; Klingspor L; Kumlien G; Le Blanc K; Ljungman P; Machaczka M; Malmberg K-J; Marschall H-U; Mattsson J; Olsson R; Omazic B; Sairafi D; Schaffer M; Svahn B-M; Svenberg P; Swartling L; Szakos A; Uhlin M; Uzunel M; Watz E; Wernerson A; Wikman A; Wikström A-C; Winiarski J; Ringdén O
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2010;162(1):146-155

Characterization of long-term mixed donor-donor chimerism after double cord blood transplantation.

Gertow J; Berglund S; Okas M; Uzunel M; Berg L; Kärre K; Mattsson J; Uhlin M
Article: INTERNATIONAL JOURNAL OF HEMATOLOGY. 2009;90(4):526-531

Stable mixed donor-donor chimerism after double cord blood transplantation.

Berglund S; Okas M; Gertow J; Uhlin M; Mattsson J

Alla övriga publikationer

Review: EXPERT OPINION ON BIOLOGICAL THERAPY. 2019;19(8):811-827

Facing the future: challenges and opportunities in adoptive T cell therapy in cancer.

Magalhaes I; Carvalho-Queiroz C; Hartana CA; Kaiser A; Lukic A; Mints M; Nilsson O; Grönlund H; Mattsson J; Berglund S
Review: EXPERT OPINION ON BIOLOGICAL THERAPY. 2017;17(6):691-699

Advances in umbilical cord blood cell therapy: the present and the future.

Berglund S; Magalhaes I; Gaballa A; Vanherberghen B; Uhlin M
Meeting abstract: BLOOD. 2016;128(22):4567

Natural Killer Cell Reconstitution after Haploidentical Hematopoietic Stem Cell Transplantation with Post-Transplant Cyclophosphamide: Elimination of Donor-Derived Mature Alloreactive NK Cells, but Favorable Conditions for Adoptive Immunotherapy

Russo A; Oliveira G; Berglund S; Greco R; Gambacorta V; Cieri N; Toffalori C; Zito L; Piemontese S; Morelli M; Giglio F; Assanelli AA; Stanghellini MTL; Bonini C; Peccatori J; Luznik L; Ciceri F; Vago L
KI thesis / dissertation: 2014

Umbilical cord blood transplantation : clinical outcome, chimerism development, and in vitro expansion of T-cells for clinical use

Berglund, Sofia

Anställningar

Anknuten till Forskning, Klinisk neurovetenskap, Karolinska Institutet, 2023-2026

Examina och utbildning

Medicine Doktorsexamen, Institutionen för laboratoriemedicin, Karolinska Institutet, 2014
Läkarexamen, Karolinska Institutet, 2008

Om mig

Forskningsbeskrivning

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI