Shao-Bo Jin

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2022;26(3):880-892

γ-Secretase modulators show selectivity for γ-secretase-mediated amyloid precursor protein intramembrane processing.

Weber TA; Lundkvist J; Wanngren J; Kvartsberg H; Jin S; Larssen P; Wu D; Oliveira DV; Minta K; Brinkmalm G; Zetterberg H; Blennow K; Nordvall G; Winblad B; Portelius E; Karlström H
Article: BMC BIOLOGY. 2021;19(1):229

MIEF1/2 orchestrate mitochondrial dynamics through direct engagement with both the fission and fusion machineries.

Yu R; Liu T; Jin S-B; Ankarcrona M; Lendahl U; Nistér M; Zhao J
Article: NEUROLOGY-GENETICS. 2021;7(3):e584

Novel Cysteine-Sparing Hypomorphic NOTCH3 A1604T Mutation Observed in a Family With Migraine and White Matter Lesions.

Arnardottir S; Del Gaudio F; Klironomos S; Braune E-B; Lombraña AA; Oliveira DV; Jin S; Karlström H; Lendahl U; Sjöstrand C
Article: DISEASE MODELS & MECHANISMS. 2021;14(2):dmm.046300

The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression.

Wu D; Wang S; Oliveira DV; Del Gaudio F; Vanlandewijck M; Lebouvier T; Betsholtz C; Zhao J; Jin S; Lendahl U; Karlström H
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2021;9:706687

The Molecular Assembly State of Drp1 Controls its Association With the Mitochondrial Recruitment Receptors Mff and MIEF1/2.

Yu R; Jin S-B; Ankarcrona M; Lendahl U; Nistér M; Zhao J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2021;296:100593

PIM-induced phosphorylation of Notch3 promotes breast cancer tumorigenicity in a CSL-independent fashion.

Landor SKJ; Santio NM; Eccleshall WB; Paramonov VM; Gagliani EK; Hall D; Jin S-B; Dahlström KM; Salminen TA; Rivero-Müller A; Lendahl U; Kovall RA; Koskinen PJ; Sahlgren C
Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2019;111(9):983-995

Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ.

Strell C; Paulsson J; Jin S-B; Tobin NP; Mezheyeuski A; Roswall P; Mutgan C; Mitsios N; Johansson H; Wickberg SM; Svedlund J; Nilsson M; Hall P; Mulder J; Radisky DC; Pietras K; Bergh J; Lendahl U; Wärnberg F; Östman A
Article: MATRIX BIOLOGY. 2019;81:107-121

Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling.

Papadakos KS; Bartoschek M; Rodriguez C; Gialeli C; Jin S-B; Lendahl U; Pietras K; Blom AM
Article: EMBO JOURNAL. 2019;38(8):e99748

Human Fis1 regulates mitochondrial dynamics through inhibition of the fusion machinery.

Yu R; Jin S-B; Lendahl U; Nistér M; Zhao J
Article: ONCOGENE. 2018;37(46):6083-6095

Notch signaling promotes a HIF2α-driven hypoxic response in multiple tumor cell types.

Mutvei AP; Landor SK-J; Fox R; Braune E-B; Tsoi YL; Phoon YP; Sahlgren C; Hartman J; Bergh J; Jin S; Lendahl U
Article: MOLECULAR THERAPY. 2018;26(7):1644-1659

Human ISL1+ Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction.

Foo KS; Lehtinen ML; Leung CY; Lian X; Xu J; Keung W; Geng L; Kolstad TRS; Thams S; Wong AO-T; Wong N; Bylund K; Zhou C; He X; Jin S-B; Clarke J; Lendahl U; Li RA; Louch WE; Chien KR
Article: BLOOD. 2018;131(15):1712-1719

Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis.

Duarte S; Woll PS; Buza-Vidas N; Chin DWL; Boukarabila H; Luís TC; Stenson L; Bouriez-Jones T; Ferry H; Mead AJ; Atkinson D; Jin S; Clark S-A; Wu B; Repapi E; Gray N; Taylor S; Mutvei AP; Tsoi YL; Nerlov C; Lendahl U; Jacobsen SEW
Article: SCIENTIFIC REPORTS. 2017;7(1):880

MIEF1/2 function as adaptors to recruit Drp1 to mitochondria and regulate the association of Drp1 with Mff.

Yu R; Liu T; Jin S-B; Ning C; Lendahl U; Nistér M; Zhao J
Article: STEM CELL REPORTS. 2016;6(5):643-651

Loss of CSL Unlocks a Hypoxic Response and Enhanced Tumor Growth Potential in Breast Cancer Cells.

Braune E-B; Tsoi YL; Phoon YP; Landor S; Silva Cascales H; Ramsköld D; Deng Q; Lindqvist A; Lian X; Sahlgren C; Jin S-B; Lendahl U
Article: BREAST CANCER RESEARCH. 2015;17(1):109

Decoding breast cancer tissue-stroma interactions using species-specific sequencing.

Chivukula IV; Ramsköld D; Storvall H; Anderberg C; Jin S; Mamaeva V; Sahlgren C; Pietras K; Sandberg R; Lendahl U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(2):409-420

Notch3 is necessary for blood vessel integrity in the central nervous system.

Henshall TL; Keller A; He L; Johansson BR; Wallgard E; Raschperger E; Mäe MA; Jin S; Betsholtz C; Lendahl U
Article: CELL RESEARCH. 2014;24(4):433-450

PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner.

Sjöqvist M; Antfolk D; Ferraris S; Rraklli V; Haga C; Antila C; Mutvei A; Imanishi SY; Holmberg J; Jin S; Eriksson JE; Lendahl U; Sahlgren C
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2014;289(3):1540-1550

Characterization of intermediate steps in amyloid beta (Aβ) production under near-native conditions.

Olsson F; Schmidt S; Althoff V; Munter LM; Jin S; Rosqvist S; Lendahl U; Multhaup G; Lundkvist J
Article: EXPERIMENTAL CELL RESEARCH. 2013;319(18):2893-2904

The mitochondrial elongation factors MIEF1 and MIEF2 exert partially distinct functions in mitochondrial dynamics.

Liu T; Yu R; Jin S-B; Han L; Lendahl U; Zhao J; Nistér M
Article: ONCOGENE. 2013;32(41):4892-4902

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ.

Jin S; Mutvei AP; Chivukula IV; Andersson ER; Ramsköld D; Sandberg R; Lee KL; Kronqvist P; Mamaeva V; Ostling P; Mpindi J-P; Kallioniemi O; Screpanti I; Poellinger L; Sahlgren C; Lendahl U
Article: STEM CELLS AND DEVELOPMENT. 2013;22(9):1360-1369

Hypoxia-induced arterial differentiation requires adrenomedullin and notch signaling.

Lanner F; Lee KL; Ortega GC; Sohl M; Li X; Jin S; Hansson EM; Claesson-Welsh L; Poellinger L; Lendahl U; Farnebo F
Article: PLOS ONE. 2013;8(5):e62959

Notch signaling maintains neural rosette polarity.

Main H; Radenkovic J; Jin S-B; Lendahl U; Andersson ER
Article: JOURNAL OF NEUROSCIENCE. 2012;32(48):17297-17305

Alzheimer's disease: presenilin 2-sparing γ-secretase inhibition is a tolerable Aβ peptide-lowering strategy.

Borgegård T; Gustavsson S; Nilsson C; Parpal S; Klintenberg R; Berg A-L; Rosqvist S; Serneels L; Svensson S; Olsson F; Jin S; Yan H; Wanngren J; Jureus A; Ridderstad-Wollberg A; Wollberg P; Stockling K; Karlström H; Malmberg A; Lund J; Arvidsson PI; De Strooper B; Lendahl U; Lundkvist J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(46):18814-18819

Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms.

Landor SK-J; Mutvei AP; Mamaeva V; Jin S; Busk M; Borra R; Grönroos TJ; Kronqvist P; Lendahl U; Sahlgren CM
Article: EMBO JOURNAL. 2011;30(14):2762-2778

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission.

Zhao J; Liu T; Jin S; Wang X; Qu M; Uhlén P; Tomilin N; Shupliakov O; Lendahl U; Nistér M
Article: EXPERIMENTAL CELL RESEARCH. 2010;316(9):1610-1624

Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells.

Main H; Lee KL; Yang H; Haapa-Paananen S; Edgren H; Jin S; Sahlgren C; Kallioniemi O; Poellinger L; Lim B; Lendahl U
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;393(1):21-27

Evidence for dimeric BACE-mediated APP processing.

Jin S; Agerman K; Kolmodin K; Gustafsson E; Dahlqvist C; Jureus A; Liu G; Fälting J; Berg S; Lundkvist J; Lendahl U
Article: JOURNAL OF CELL SCIENCE. 2009;122(Pt 13):2252-2262

The novel conserved mitochondrial inner-membrane protein MTGM regulates mitochondrial morphology and cell proliferation.

Zhao J; Liu T; Jin S-B; Tomilin N; Castro J; Shupliakov O; Lendahl U; Nistér M
Article: JOURNAL OF CELL BIOLOGY. 2009;184(4):555-568

Specific combinations of SR proteins associate with single pre-messenger RNAs in vivo and contribute different functions.

Björk P; Jin S; Zhao J; Singh OP; Persson J-O; Hellman U; Wieslander L
Article: CIRCULATION RESEARCH. 2008;102(12):1483-1491

Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells.

Jin S; Hansson EM; Tikka S; Lanner F; Sahlgren C; Farnebo F; Baumann M; Kalimo H; Lendahl U
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(17):6392-6397

Notch signaling mediates hypoxia-induced tumor cell migration and invasion.

Sahlgren C; Gustafsson MV; Jin S; Poellinger L; Lendahl U
Article: DEVELOPMENTAL CELL. 2005;9(5):617-628

Hypoxia requires notch signaling to maintain the undifferentiated cell state.

Gustafsson MV; Zheng X; Pereira T; Gradin K; Jin S; Lundkvist J; Ruas JL; Poellinger L; Lendahl U; Bondesson M
Article: BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY. 2003;38(Pt 3):231-239

An improved dual-expression concept, generating high-quality antibodies for proteomics research.

Falk R; Agaton C; Kiesler E; Jin S; Wieslander L; Visa N; Hober S; Ståhl S
Article: EUROPEAN JOURNAL OF CELL BIOLOGY. 2002;81(3):125-137

A novel protein localized to the fibrillar compartment of the nucleolus and to the brush border of a secretory cell.

Sun X; Zhao J; Jin S; Palka K; Visa N; Aissouni Y; Daneholt B; Alzhanova-Ericsson AT
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Meeting abstract: CANCER RESEARCH. 2016;76:b41

Cell-contact dependent epithelial-stromal cross talk, including a modulation of stromal PDGFR expression, drives the progression of early-stage breast cancer lesions

Strell C; Paulsson J; Mezheyeuski A; Jin S-B; Roswall P; Andrea J; Frings O; Warnberg F; Johansson H; Jirstrom K; Pietras K; Hall P; Lendahl U; Betsholtz C; Radisky DC; Ostman A

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