Rickard Sandberg

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Utbildning - Doktorandstudier, institutionen för mikrobiologi, tumör- och cellbiologi (MTC), Karolinska Institutet, Stockholm, Sweden 2000-2004. - Postdoktorala studier, Massachusetts Institute of Technology (MIT), Cambridge, US 2005-2007. - Forskarassistent, institutionen för cell- och molekylärbiologi (CMB), Karolinska Institutet, Sweden 2008-2013. - Docent, institutionen för cell- och molekylärbiologi (CMB), Karolinska Institutet, Sweden 2013- Akademiska priser och utmärkelser - Torsten Söderbergs akademiprofessur i medicin 2022 - Elected Member of EMBO 2019. - Elected Member of the Nobel Assembly at Karolinska Institutet 2019. - Anders Jahre's medical prize for young medical researchers (Nordic prize) 2014 - EMBO Young Investigator 2012 - Sven and Ebba-Christina Hagbergs Prize 2012

Utvalda publikationer

Article: NATURE BIOTECHNOLOGY. 2020;38(6):708-714

Single-cell RNA counting at allele and isoform resolution using Smart-seq3.

Hagemann-Jensen M; Ziegenhain C; Chen P; Ramsköld D; Hendriks G-J; Larsson AJM; Faridani OR; Sandberg R
Article: NATURE COMMUNICATIONS. 2019;10(1):3138

NASC-seq monitors RNA synthesis in single cells.

Hendriks G-J; Jung LA; Larsson AJM; Lidschreiber M; Andersson Forsman O; Lidschreiber K; Cramer P; Sandberg R
Article: NATURE. 2019;565(7738):251-254

Genomic encoding of transcriptional burst kinetics.

Larsson AJM; Johnsson P; Hagemann-Jensen M; Hartmanis L; Faridani OR; Reinius B; Segerstolpe Å; Rivera CM; Ren B; Sandberg R
Article: SCIENCE. 2014;343(6167):193-196

Single-cell RNA-seq reveals dynamic, random monoallelic gene expression in mammalian cells.

Deng Q; Ramsköld D; Reinius B; Sandberg R
Article: NATURE METHODS. 2013;10(11):1096-1098

Smart-seq2 for sensitive full-length transcriptome profiling in single cells.

Picelli S; Björklund ÅK; Faridani OR; Sagasser S; Winberg G; Sandberg R

Artiklar

Article: CANCER RESEARCH. 2024;84(2):211-225

Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts.

Moura PL; Mortera-Blanco T; Hofman IJ; Todisco G; Kretzschmar WW; Björklund A-C; Creignou M; Hagemann-Jensen M; Ziegenhain C; Cabrerizo Granados D; Barbosa I; Walldin G; Jansson M; Ashley N; Mead AJ; Lundin V; Dimitriou M; Yoshizato T; Woll PS; Ogawa S; Sandberg R; Jacobsen SEW; Hellström-Lindberg E
Article: NATURE AGING. 2023;3(11):1430-1445

Spatial and single-cell profiling of the metabolome, transcriptome and epigenome of the aging mouse liver.

Nikopoulou C; Kleinenkuhnen N; Parekh S; Sandoval T; Ziegenhain C; Schneider F; Giavalisco P; Donahue K-F; Vesting AJ; Kirchner M; Bozukova M; Vossen C; Altmüller J; Wunderlich T; Sandberg R; Kondylis V; Tresch A; Tessarz P
Article: AGING-US. 2023;15(12):5240-5265

Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis.

Salignon J; Faridani OR; Miliotis T; Janssens GE; Chen P; Zarrouki B; Sandberg R; Davidsson P; Riedel CG
Article: DEVELOPMENTAL CELL. 2023;58(6):450-460.e6

A small noncoding RNA links ribosome recovery and translation control to dedifferentiation during salamander limb regeneration.

Subramanian E; Elewa A; Brito G; Kumar A; Segerstolpe Å; Karampelias C; Björklund Å; Sandberg R; Echeverri K; Lui W-O; Andersson O; Simon A
Article: NATURE COMMUNICATIONS. 2023;14(1):982

Reconstructing clonal tree for phylo-phenotypic characterization of cancer using single-cell transcriptomics.

Jun S-H; Toosi H; Mold J; Engblom C; Chen X; O'Flanagan C; Hagemann-Jensen M; Sandberg R; Aparicio S; Hartman J; Roth A; Lagergren J
Article: NATURE BIOTECHNOLOGY. 2022;40(10):1452-1457

Scalable single-cell RNA sequencing from full transcripts with Smart-seq3xpress.

Hagemann-Jensen M; Ziegenhain C; Sandberg R
Article: NATURE METHODS. 2022;19(5):560-566

Molecular spikes: a gold standard for single-cell RNA counting.

Ziegenhain C; Hendriks G-J; Hagemann-Jensen M; Sandberg R
Article: NATURE GENETICS. 2022;54(3):306-317

Transcriptional kinetics and molecular functions of long noncoding RNAs.

Johnsson P; Ziegenhain C; Hartmanis L; Hendriks G-J; Hagemann-Jensen M; Reinius B; Sandberg R
Article: NATURE COMMUNICATIONS. 2021;12(1):6216

BAMboozle removes genetic variation from human sequence data for open data sharing.

Ziegenhain C; Sandberg R
Article: NATURE. 2021;598(7879):144-150

Phenotypic variation of transcriptomic cell types in mouse motor cortex.

Scala F; Kobak D; Bernabucci M; Bernaerts Y; Cadwell CR; Castro JR; Hartmanis L; Jiang X; Laturnus S; Miranda E; Mulherkar S; Tan ZH; Yao Z; Zeng H; Sandberg R; Berens P; Tolias AS
Article: NATURE. 2021;598(7879):86-102

A multimodal cell census and atlas of the mammalian primary motor cortex.

BRAIN Initiative Cell Census Network (BICCN)
Article: CELL REPORTS. 2021;35(8):109174

Divergent clonal differentiation trajectories establish CD8+ memory T cell heterogeneity during acute viral infections in humans.

Mold JE; Modolo L; Hård J; Zamboni M; Larsson AJM; Stenudd M; Eriksson C-J; Durif G; Ståhl PL; Borgström E; Picelli S; Reinius B; Sandberg R; Réu P; Talavera-Lopez C; Andersson B; Blom K; Sandberg JK; Picard F; Michaëlsson J; Frisén J
Article: NATURE COMMUNICATIONS. 2021;12(1):2141

Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes.

He B; Chen P; Zambrano S; Dabaghie D; Hu Y; Möller-Hackbarth K; Unnersjö-Jess D; Korkut GG; Charrin E; Jeansson M; Bintanel-Morcillo M; Witasp A; Wennberg L; Wernerson A; Schermer B; Benzing T; Ernfors P; Betsholtz C; Lal M; Sandberg R; Patrakka J
Article: PLOS COMPUTATIONAL BIOLOGY. 2021;17(3):e1008772

Transcriptional bursts explain autosomal random monoallelic expression and affect allelic imbalance.

Larsson AJM; Ziegenhain C; Hagemann-Jensen M; Reinius B; Jacob T; Dalessandri T; Hendriks G-J; Kasper M; Sandberg R
Article: PLOS ONE. 2021;16(4):e0250282

Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations.

Diaz-Gallo L-M; Brynedal B; Westerlind H; Sandberg R; Ramsköld D
Article: NATURE NANOTECHNOLOGY. 2021;16(1):85-95

A DNA-nanoassembly-based approach to map membrane protein nanoenvironments.

Ambrosetti E; Bernardinelli G; Hoffecker I; Hartmanis L; Kiriako G; de Marco A; Sandberg R; Högberg B; Teixeira AI
Article: GENOME RESEARCH. 2020;30(8):1083-1096

LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy.

Nichterwitz S; Nijssen J; Storvall H; Schweingruber C; Comley LH; Allodi I; Lee MVD; Deng Q; Sandberg R; Hedlund E
Article: NATURE BIOTECHNOLOGY. 2020;38(6):747-755

Benchmarking single-cell RNA-sequencing protocols for cell atlas projects.

Mereu E; Lafzi A; Moutinho C; Ziegenhain C; McCarthy DJ; Álvarez-Varela A; Batlle E; Sagar; Grün D; Lau JK; Boutet SC; Sanada C; Ooi A; Jones RC; Kaihara K; Brampton C; Talaga Y; Sasagawa Y; Tanaka K; Hayashi T; Braeuning C; Fischer C; Sauer S; Trefzer T; Conrad C; Adiconis X; Nguyen LT; Regev A; Levin JZ; Parekh S; Janjic A; Wange LE; Bagnoli JW; Enard W; Gut M; Sandberg R; Nikaido I; Gut I; Stegle O; Heyn H
Article: ELIFE. 2020;9:e52951

Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex.

Cadwell CR; Scala F; Fahey PG; Kobak D; Mulherkar S; Sinz FH; Papadopoulos S; Tan ZH; Johnsson P; Hartmanis L; Li S; Cotton RJ; Tolias KF; Sandberg R; Berens P; Jiang X; Tolias AS
Article: CELL STEM CELL. 2020;26(3):441-457.e7

The Molecular Anatomy of Mouse Skin during Hair Growth and Rest.

Joost S; Annusver K; Jacob T; Sun X; Dalessandri T; Sivan U; Sequeira I; Sandberg R; Kasper M
Article: BASIC RESEARCH IN CARDIOLOGY. 2019;115(1):7

Cell shape determines gene expression: cardiomyocyte morphotypic transcriptomes.

Haftbaradaran Esfahani P; ElBeck Z; Sagasser S; Li X; Hossain MB; Talukdar HA; Sandberg R; Knöll R
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2019;26(10):963-969

X-chromosome upregulation is driven by increased burst frequency.

Larsson AJM; Coucoravas C; Sandberg R; Reinius B
Article: NATURE COMMUNICATIONS. 2019;10(1):4174

Layer 4 of mouse neocortex differs in cell types and circuit organization between sensory areas.

Scala F; Kobak D; Shan S; Bernaerts Y; Laturnus S; Cadwell CR; Hartmanis L; Froudarakis E; Castro JR; Tan ZH; Papadopoulos S; Patel SS; Sandberg R; Berens P; Jiang X; Tolias AS
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2019;39(7):1402-1418

Intussusceptive Vascular Remodeling Precedes Pathological Neovascularization.

Ali Z; Mukwaya A; Biesemeier A; Ntzouni M; Ramsköld D; Giatrellis S; Mammadzada P; Cao R; Lennikov A; Marass M; Gerri C; Hildesjö C; Taylor M; Deng Q; Peebo B; Del Peso L; Kvanta A; Sandberg R; Schraermeyer U; Andre H; Steffensen JF; Lagali N; Cao Y; Kele J; Jensen LD
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2019;39(7):1432-1447

Disruption of the Extracellular Matrix Progressively Impairs Central Nervous System Vascular Maturation Downstream of β-Catenin Signaling.

Jensen LD; Hot B; Ramsköld D; Germano RFV; Yokota C; Giatrellis S; Lauschke VM; Hubmacher D; Li MX; Hupe M; Arnold TD; Sandberg R; Frisén J; Trusohamn M; Martowicz A; Wisniewska-Kruk J; Nyqvist D; Adams RH; Apte SS; Vanhollebeke B; Stenman JM; Kele J
Article: NATURE PROTOCOLS. 2018;13(10):2407-2424

Small-seq for single-cell small-RNA sequencing.

Hagemann-Jensen M; Abdullayev I; Sandberg R; Faridani OR
Article: EXPERIMENTAL CELL RESEARCH. 2018;371(1):130-138

Exploring parasite heterogeneity using single-cell RNA-seq reveals a gene signature among sexual stage Plasmodium falciparum parasites.

Ngara M; Palmkvist M; Sagasser S; Hjelmqvist D; Björklund ÅK; Wahlgren M; Ankarklev J; Sandberg R
Article: NATURE COMMUNICATIONS. 2018;9(1):1873

Parental haplotype-specific single-cell transcriptomics reveal incomplete epigenetic reprogramming in human female germ cells.

Vértesy Á; Arindrarto W; Roost MS; Reinius B; Torrens-Juaneda V; Bialecka M; Moustakas I; Ariyurek Y; Kuijk E; Mei H; Sandberg R; van Oudenaarden A; Chuva de Sousa Lopes SM
Article: NATURE METHODS. 2018;15(5):339-342

Identification of spatial expression trends in single-cell gene expression data.

Edsgärd D; Johnsson P; Sandberg R
Article: GASTROENTEROLOGY. 2018;154(4):1080-1095

Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations.

Andersson ER; Chivukula IV; Hankeova S; Sjöqvist M; Tsoi YL; Ramsköld D; Masek J; Elmansuri A; Hoogendoorn A; Vazquez E; Storvall H; Netušilová J; Huch M; Fischler B; Ellis E; Contreras A; Nemeth A; Chien KC; Clevers H; Sandberg R; Bryja V; Lendahl U
Article: NATURE COMMUNICATIONS. 2017;8(1):2286

Reading and editing the Pleurodeles waltl genome reveals novel features of tetrapod regeneration.

Elewa A; Wang H; Talavera-López C; Joven A; Brito G; Kumar A; Hameed LS; Penrad-Mobayed M; Yao Z; Zamani N; Abbas Y; Abdullayev I; Sandberg R; Grabherr M; Andersson B; Simon A
Article: NATURE PROTOCOLS. 2017;12(12):2531-2553

Multimodal profiling of single-cell morphology, electrophysiology, and gene expression using Patch-seq.

Cadwell CR; Scala F; Li S; Livrizzi G; Shen S; Sandberg R; Jiang X; Tolias AS
Article: EMBO JOURNAL. 2017;36(14):2107-2125

A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.

Malenczyk K; Girach F; Szodorai E; Storm P; Segerstolpe Å; Tortoriello G; Schnell R; Mulder J; Romanov RA; Borók E; Piscitelli F; Di Marzo V; Szabó G; Sandberg R; Kubicek S; Lubec G; Hökfelt T; Wagner L; Groop L; Harkany T
Article: NATURE MEDICINE. 2017;23(6):692-702

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia.

Giustacchini A; Thongjuea S; Barkas N; Woll PS; Povinelli BJ; Booth CAG; Sopp P; Norfo R; Rodriguez-Meira A; Ashley N; Jamieson L; Vyas P; Anderson K; Segerstolpe Å; Qian H; Olsson-Strömberg U; Mustjoki S; Sandberg R; Jacobsen SEW; Mead AJ
Article: ELIFE. 2017;6:e22906

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo.

Posfai E; Petropoulos S; de Barros FRO; Schell JP; Jurisica I; Sandberg R; Lanner F; Rossant J
Article: CELL STEM CELL. 2017;20(1):29-40

Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.

Kee N; Volakakis N; Kirkeby A; Dahl L; Storvall H; Nolbrant S; Lahti L; Björklund ÅK; Gillberg L; Joodmardi E; Sandberg R; Parmar M; Perlmann T
Article: NATURE BIOTECHNOLOGY. 2016;34(12):1264-1266

Single-cell sequencing of the small-RNA transcriptome.

Faridani OR; Abdullayev I; Hagemann-Jensen M; Schell JP; Lanner F; Sandberg R
Article: NATURE IMMUNOLOGY. 2016;17(12):1424-1435

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.

Luis TC; Luc S; Mizukami T; Boukarabila H; Thongjuea S; Woll PS; Azzoni E; Giustacchini A; Lutteropp M; Bouriez-Jones T; Vaidya H; Mead AJ; Atkinson D; Böiers C; Carrelha J; Macaulay IC; Patient R; Geissmann F; Nerlov C; Sandberg R; de Bruijn MFTR; Blackburn CC; Godin I; Jacobsen SEW
Article: NATURE GENETICS. 2016;48(11):1430-1435

Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq.

Reinius B; Mold JE; Ramsköld D; Deng Q; Johnsson P; Michaëlsson J; Frisén J; Sandberg R
Article: CELL METABOLISM. 2016;24(4):593-607

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.

Segerstolpe Å; Palasantza A; Eliasson P; Andersson E-M; Andréasson A-C; Sun X; Picelli S; Sabirsh A; Clausen M; Bjursell MK; Smith DM; Kasper M; Ämmälä C; Sandberg R
Article: BIOINFORMATICS. 2016;32(19):3038-3040

scphaser: haplotype inference using single-cell RNA-seq data.

Edsgärd D; Reinius B; Sandberg R
Article: GENOME RESEARCH. 2016;26(10):1342-1354

Single-cell analyses of X Chromosome inactivation dynamics and pluripotency during differentiation.

Chen G; Schell JP; Benitez JA; Petropoulos S; Yilmaz M; Reinius B; Alekseenko Z; Shi L; Hedlund E; Lanner F; Sandberg R; Deng Q
Article: NATURE COMMUNICATIONS. 2016;7:12139

Laser capture microscopy coupled with Smart-seq2 for precise spatial transcriptomic profiling.

Nichterwitz S; Chen G; Aguila Benitez J; Yilmaz M; Storvall H; Cao M; Sandberg R; Deng Q; Hedlund E
Article: CELL. 2016;165(4):1012-1026

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos.

Petropoulos S; Edsgärd D; Reinius B; Deng Q; Panula SP; Codeluppi S; Plaza Reyes A; Linnarsson S; Sandberg R; Lanner F
Article: NATURE IMMUNOLOGY. 2016;17(4):451-460

The heterogeneity of human CD127(+) innate lymphoid cells revealed by single-cell RNA sequencing.

Björklund ÅK; Forkel M; Picelli S; Konya V; Theorell J; Friberg D; Sandberg R; Mjösberg J
Article: NATURE BIOTECHNOLOGY. 2016;34(2):199-203

Electrophysiological, transcriptomic and morphologic profiling of single neurons using Patch-seq.

Cadwell CR; Palasantza A; Jiang X; Berens P; Deng Q; Yilmaz M; Reimer J; Shen S; Bethge M; Tolias KF; Sandberg R; Tolias AS
Article: STEM CELLS TRANSLATIONAL MEDICINE. 2015;4(10):1199-1213

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome.

Simonson OE; Mougiakakos D; Heldring N; Bassi G; Johansson HJ; Dalén M; Jitschin R; Rodin S; Corbascio M; El Andaloussi S; Wiklander OPB; Nordin JZ; Skog J; Romain C; Koestler T; Hellgren-Johansson L; Schiller P; Joachimsson P-O; Hägglund H; Mattsson M; Lehtiö J; Faridani OR; Sandberg R; Korsgren O; Krampera M; Weiss DJ; Grinnemo K-H; Le Blanc K
Article: BREAST CANCER RESEARCH. 2015;17(1):109

Decoding breast cancer tissue-stroma interactions using species-specific sequencing.

Chivukula IV; Ramsköld D; Storvall H; Anderberg C; Jin S; Mamaeva V; Sahlgren C; Pietras K; Sandberg R; Lendahl U
Article: GENOME BIOLOGY. 2015;16(1):156

Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution.

Sahlén P; Abdullayev I; Ramsköld D; Matskova L; Rilakovic N; Lötstedt B; Albert TJ; Lundeberg J; Sandberg R
Article: INTERNATIONAL JOURNAL OF CANCER. 2015;136(5):E230-E241

Novel functions and targets of miR-944 in human cervical cancer cells.

Xie H; Lee L; Scicluna P; Kavak E; Larsson C; Sandberg R; Lui W-O
Article: GENOME RESEARCH. 2014;24(12):2033-2040

Tn5 transposase and tagmentation procedures for massively scaled sequencing projects.

Picelli S; Björklund AK; Reinius B; Sagasser S; Winberg G; Sandberg R
Article: CELL STEM CELL. 2014;15(5):619-633

BMP signaling and its pSMAD1/5 target genes differentially regulate hair follicle stem cell lineages.

Genander M; Cook PJ; Ramsköld D; Keyes BE; Mertz AF; Sandberg R; Fuchs E
Article: CANCER CELL. 2014;25(6):794-808

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Woll PS; Kjällquist U; Chowdhury O; Doolittle H; Wedge DC; Thongjuea S; Erlandsson R; Ngara M; Anderson K; Deng Q; Mead AJ; Stenson L; Giustacchini A; Duarte S; Giannoulatou E; Taylor S; Karimi M; Scharenberg C; Mortera-Blanco T; Macaulay IC; Clark S-A; Dybedal I; Josefsen D; Fenaux P; Hokland P; Holm MS; Cazzola M; Malcovati L; Tauro S; Bowen D; Boultwood J; Pellagatti A; Pimanda JE; Unnikrishnan A; Vyas P; Göhring G; Schlegelberger B; Tobiasson M; Kvalheim G; Constantinescu SN; Nerlov C; Nilsson L; Campbell PJ; Sandberg R; Papaemmanuil E; Hellström-Lindberg E; Linnarsson S; Jacobsen SEW
Article: CANCER DISCOVERY. 2014;4(4):434-451

RNA helicase A is a downstream mediator of KIF1Bβ tumor-suppressor function in neuroblastoma.

Chen ZX; Wallis K; Fell SM; Sobrado VR; Hemmer MC; Ramsköld D; Hellman U; Sandberg R; Kenchappa RS; Martinson T; Johnsen JI; Kogner P; Schlisio S
Article: NATURE METHODS. 2014;11(1):22-24

Entering the era of single-cell transcriptomics in biology and medicine.

Sandberg R
Article: NATURE PROTOCOLS. 2014;9(1):171-181

Full-length RNA-seq from single cells using Smart-seq2.

Picelli S; Faridani OR; Björklund AK; Winberg G; Sagasser S; Sandberg R
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2013;20(12):1367-1376

The human cap-binding complex is functionally connected to the nuclear RNA exosome.

Andersen PR; Domanski M; Kristiansen MS; Storvall H; Ntini E; Verheggen C; Schein A; Bunkenborg J; Poser I; Hallais M; Sandberg R; Hyman A; LaCava J; Rout MP; Andersen JS; Bertrand E; Jensen TH
Article: CELL STEM CELL. 2013;13(5):535-548

Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells.

Böiers C; Carrelha J; Lutteropp M; Luc S; Green JCA; Azzoni E; Woll PS; Mead AJ; Hultquist A; Swiers G; Perdiguero EG; Macaulay IC; Melchiori L; Luis TC; Kharazi S; Bouriez-Jones T; Deng Q; Pontén A; Atkinson D; Jensen CT; Sitnicka E; Geissmann F; Godin I; Sandberg R; de Bruijn MFTR; Jacobsen SEW
Article: ONCOGENE. 2013;32(41):4892-4902

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ.

Jin S; Mutvei AP; Chivukula IV; Andersson ER; Ramsköld D; Sandberg R; Lee KL; Kronqvist P; Mamaeva V; Ostling P; Mpindi J-P; Kallioniemi O; Screpanti I; Poellinger L; Sahlgren C; Lendahl U
Article: EXPERIMENTAL CELL RESEARCH. 2013;319(8):1187-1197

A reference transcriptome and inferred proteome for the salamander Notophthalmus viridescens.

Abdullayev I; Kirkham M; Björklund ÅK; Simon A; Sandberg R
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(18):7330-7335

SoxB1-driven transcriptional network underlies neural-specific interpretation of morphogen signals.

Oosterveen T; Kurdija S; Ensterö M; Uhde CW; Bergsland M; Sandberg M; Sandberg R; Muhr J; Ericson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(6):2360-2365

Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons.

Kadkhodaei B; Alvarsson A; Schintu N; Ramsköld D; Volakakis N; Joodmardi E; Yoshitake T; Kehr J; Decressac M; Björklund A; Sandberg R; Svenningsson P; Perlmann T
Article: PLOS ONE. 2013;8(1):e53822

Efficient and comprehensive representation of uniqueness for next-generation sequencing by minimum unique length analyses.

Storvall H; Ramsköld D; Sandberg R
Article: BMC GENOMICS. 2012;13:607

Abundance of female-biased and paucity of male-biased somatically expressed genes on the mouse X-chromosome.

Reinius B; Johansson MM; Radomska KJ; Morrow EH; Pandey GK; Kanduri C; Sandberg R; Williams RW; Jazin E
Article: NATURE BIOTECHNOLOGY. 2012;30(8):777-782

Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells.

Ramsköld D; Luo S; Wang Y-C; Li R; Deng Q; Faridani OR; Daniels GA; Khrebtukova I; Loring JF; Laurent LC; Schroth GP; Sandberg R
Article: METHODS IN MOLECULAR BIOLOGY. 2012;802:259-274

How to analyze gene expression using RNA-sequencing data.

Ramsköld D; Kavak E; Sandberg R
Article: GENES & DEVELOPMENT. 2011;25(23):2453-2464

Sequentially acting Sox transcription factors in neural lineage development.

Bergsland M; Ramsköld D; Zaouter C; Klum S; Sandberg R; Muhr J
Article: NATURE. 2011;479(7371):74-79

CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing.

Shukla S; Kavak E; Gregory M; Imashimizu M; Shutinoski B; Kashlev M; Oberdoerffer P; Sandberg R; Oberdoerffer S
Article: CELL STEM CELL. 2011;8(6):663-675

Transcription factor-induced lineage selection of stem-cell-derived neural progenitor cells.

Panman L; Andersson E; Alekseenko Z; Hedlund E; Kee N; Mong J; Uhde CW; Deng Q; Sandberg R; Stanton LW; Ericson J; Perlmann T
Article: PLOS COMPUTATIONAL BIOLOGY. 2009;5(12):e1000598

An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data.

Ramsköld D; Wang ET; Burge CB; Sandberg R
Article: NATURE. 2008;456(7221):470-476

Alternative isoform regulation in human tissue transcriptomes.

Wang ET; Sandberg R; Luo S; Khrebtukova I; Zhang L; Mayr C; Kingsmore SF; Schroth GP; Burge CB
Article: SCIENCE. 2008;320(5883):1643-1647

Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites.

Sandberg R; Neilson JR; Sarma A; Sharp PA; Burge CB
Article: RNA. 2007;13(11):1894-1910

Determinants of targeting by endogenous and exogenous microRNAs and siRNAs.

Nielsen CB; Shomron N; Sandberg R; Hornstein E; Kitzman J; Burge CB
Article: BMC BIOINFORMATICS. 2007;8:48

Improved precision and accuracy for microarrays using updated probe set definitions.

Sandberg R; Larsson O
Article: OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY. 2006;10(3):381-397

Comparative microarray analysis.

Larsson O; Wennmalm K; Sandberg R
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(6):2052-2057

Assessment of tumor characteristic gene expression in cell lines using a tissue similarity index (TSI).

Sandberg R; Ernberg I
Article: GENOME BIOLOGY. 2005;6(8):R65

The molecular portrait of in vitro growth by meta-analysis of gene-expression profiles.

Sandberg R; Ernberg I
Article: GENE. 2003;311:35-42

Quantifying the species-specificity in genomic signatures, synonymous codon choice, amino acid usage and G+C content.

Sandberg R; Bränden C-I; Ernberg I; Cöster J
Article: GENOME RESEARCH. 2001;11(8):1404-1409

Capturing whole-genome characteristics in short sequences using a naïve Bayesian classifier.

Sandberg R; Winberg G; Bränden CI; Kaske A; Ernberg I; Cöster J
Article: MICROBIOLOGY-SGM. 2000;146 ( Pt 10):2665-2670

Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layer.

Good L; Sandberg R; Larsson O; Nielsen PE; Wahlestedt C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000;97(20):11038-11043

Regional and strain-specific gene expression mapping in the adult mouse brain.

Sandberg R; Yasuda R; Pankratz DG; Carter TA; Del Rio JA; Wodicka L; Mayford M; Lockhart DJ; Barlow C
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Letter: CELL RESEARCH. 2023;33(11):883-886

Platelet and myeloid lineage biases of transplanted single perinatal mouse hematopoietic stem cells.

Belander Strålin K; Carrelha J; Winroth A; Ziegenhain C; Hagemann-Jensen M; Kettyle LM; Hillen A; Högstrand K; Markljung E; Grasso F; Seki M; Mazzi S; Meng Y; Wu B; Chari E; Lehander M; Sandberg R; Woll PS; Jacobsen SEW
Editorial comment: NATURE METHODS. 2022;19(5):530-531

Novel spike-ins for single-cell sequencing enable ground-truth RNA counting.
Corrigendum: NATURE BIOTECHNOLOGY. 2020;38(3):374

Author Correction: Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells.

Ramsköld D; Luo S; Wang Y-C; Li R; Deng Q; Faridani OR; Daniels GA; Khrebtukova I; Loring JF; Laurent LC; Schroth GP; Sandberg R
Corrigendum: NATURE COMMUNICATIONS. 2019;10(1):5075

Author Correction: Layer 4 of mouse neocortex differs in cell types and circuit organization between sensory areas.

Scala F; Kobak D; Shan S; Bernaerts Y; Laturnus S; Cadwell CR; Hartmanis L; Froudarakis E; Castro JR; Tan ZH; Papadopoulos S; Patel SS; Sandberg R; Berens P; Jiang X; Tolias AS
Letter: NATURE GENETICS. 2018;50(9):1199-1200

Reply to 'High prevalence of clonal monoallelic expression'.

Reinius B; Sandberg R
Letter: NATURE METHODS. 2018;15(5):305-307

Computational correction of index switching in multiplexed sequencing libraries.

Larsson AJM; Stanley G; Sinha R; Weissman IL; Sandberg R
Editorial comment: BMC BIOLOGY. 2017;15(1):58

Q&A: using Patch-seq to profile single cells.

Cadwell CR; Sandberg R; Jiang X; Tolias AS
Editorial comment: OBSTETRICAL & GYNECOLOGICAL SURVEY. 2016;71(1):29-30

Adult Human and Mouse Ovaries Lack DDX4-Expressing Functional Oogonial Stem Cells EDITORIAL COMMENT

Zhang H; Panula S; Petropoulos S; Edsgard D; Busayavalasa K; Liu L; Li X; Risal S; Shen Y; Shao J; Liu M; Li S; Zhang D; Zhang X; Gerner RR; Sheikhi M; Damdimopoulou P; Sandberg R; Douagi I; Gustafsson J-A; Liu L; Lanner F; Hovatta O; Liu K
Review: NATURE REVIEWS GENETICS. 2015;16(11):653-664

Random monoallelic expression of autosomal genes: stochastic transcription and allele-level regulation.

Reinius B; Sandberg R
Letter: NATURE MEDICINE. 2015;21(10):1116-1118

Adult human and mouse ovaries lack DDX4-expressing functional oogonial stem cells.

Zhang H; Panula S; Petropoulos S; Edsgärd D; Busayavalasa K; Liu L; Li X; Risal S; Shen Y; Shao J; Liu M; Li S; Zhang D; Zhang X; Gerner RR; Sheikhi M; Damdimopoulou P; Sandberg R; Douagi I; Gustafsson J-Å; Liu L; Lanner F; Hovatta O; Liu K
Editorial comment: NATURE BIOTECHNOLOGY. 2015;33(5):490-491

Putting cells in their place.

Faridani OR; Sandberg R
Review: DEVELOPMENT. 2011;138(17):3593-3612

Notch signaling: simplicity in design, versatility in function.

Andersson ER; Sandberg R; Lendahl U
Review: EXPERIMENTAL CELL RESEARCH. 2010;316(8):1357-1364

Heterogeneity in mammalian RNA 3' end formation.

Neilson JR; Sandberg R
Letter: NATURE BIOTECHNOLOGY. 2006;24(11):1322-1323

Lack of correct data format and comparability limits future integrative microarray research.

Larsson O; Sandberg R
Review: SEMINARS IN CANCER BIOLOGY. 2005;15(5):405-412

Gene expression perturbation in vitro--a growing case for three-dimensional (3D) culture systems.

Birgersdotter A; Sandberg R; Ernberg I
Editorial comment: GENOME RESEARCH. 2003;13(11):2377-2380

Systems biology is taking off.

Ehrenberg M; Elf J; Aurell E; Sandberg R; Tegnér J

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Professor, Cell- och molekylärbiologi, Karolinska Institutet, 2015-

Examina och utbildning

Docent, Bioinformatik, Karolinska Institutet, 2013
MEDICINE DOKTORSEXAMEN, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2004
LICENTIATEXAMEN, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2002
Medicine Magisterexamen, Karolinska Institutet, 2000

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