Olov Andersson

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: NATURE COMMUNICATIONS. 2024;15(1):2367

The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling.

Xie M; Kaiser M; Gershtein Y; Schnyder D; Deviatiiarov R; Gazizova G; Shagimardanova E; Zikmund T; Kerckhofs G; Ivashkin E; Batkovskyte D; Newton PT; Andersson O; Fried K; Gusev O; Zeberg H; Kaiser J; Adameyko I; Chagin AS
Article: NATURE NANOTECHNOLOGY. 2024;19(2):237-245

Multivalent insulin receptor activation using insulin-DNA origami nanostructures.

Spratt J; Dias JM; Kolonelou C; Kiriako G; Engström E; Petrova E; Karampelias C; Cervenka I; Papanicolaou N; Lentini A; Reinius B; Andersson O; Ambrosetti E; Ruas JL; Teixeira AI
Article: DIABETOLOGIA. 2024;67(1):137-155

Adjudin improves beta cell maturation, hepatic glucose uptake and glucose homeostasis.

Ren L; Charbord J; Chu L; Kemas AM; Bertuzzi M; Mi J; Xing C; Lauschke VM; Andersson O
Article: SCIENCE ADVANCES. 2023;9(33):eadf5142

Decoding pancreatic endocrine cell differentiation and β cell regeneration in zebrafish.

Mi J; Liu K-C; Andersson O
Article: CELL METABOLISM. 2023;35(7):1242-1260.e9

Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways.

Basile G; Vetere A; Hu J; Ijaduola O; Zhang Y; Liu K-C; Eltony AM; De Jesus DF; Fukuda K; Doherty G; Leech CA; Chepurny OG; Holz GG; Yun S-H; Andersson O; Choudhary A; Wagner BK; Kulkarni RN
Article: LIFE SCIENCE ALLIANCE. 2023;6(5):e202301944

Efficient knock-in method enabling lineage tracing in zebrafish.

Mi J; Andersson O
Article: DEVELOPMENTAL CELL. 2023;58(6):450-460.e6

A small noncoding RNA links ribosome recovery and translation control to dedifferentiation during salamander limb regeneration.

Subramanian E; Elewa A; Brito G; Kumar A; Segerstolpe Å; Karampelias C; Björklund Å; Sandberg R; Echeverri K; Lui W-O; Andersson O; Simon A
Journal article: NATURE NANOTECHNOLOGY. 2023

Multivalent insulin receptor activation using insulin-DNA origami nanostructures

Spratt J; Dias JM; Kolonelou C; Kiriako G; Engstrom E; Petrova E; Karampelias C; Cervenka I; Papanicolaou N; Lentini A; Reinius B; Andersson O; Ambrosetti E; Ruas JL; Teixeira AI
Article: CELL CHEMICAL BIOLOGY. 2022;29(9):1368-1380.e5

In vivo drug discovery for increasing incretin-expressing cells identifies DYRK inhibitors that reinforce the enteroendocrine system.

Chu L; Terasaki M; Mattsson CL; Teinturier R; Charbord J; Dirice E; Liu K-C; Miskelly MG; Zhou Q; Wierup N; Kulkarni RN; Andersson O
Article: NATURE CHEMICAL BIOLOGY. 2022;18(9):942-953

MNK2 deficiency potentiates β-cell regeneration via translational regulation.

Karampelias C; Watt K; Mattsson CL; Ruiz ÁF; Rezanejad H; Mi J; Liu X; Chu L; Locasale JW; Korbutt GS; Rovira M; Larsson O; Andersson O
Article: PLOS ONE. 2022;17(8):e0272046

Association between folic acid use during pregnancy and gestational diabetes mellitus: Two population-based Nordic cohort studies.

Pazzagli L; Segovia Chacón S; Karampelias C; Cohen JM; Bröms G; Kieler H; Odsbu I; Selmer R; Andersson O; Cesta CE
Article: PEDIATRIC DIABETES. 2021;22(7):969-973

Investigating the association between prenatal exposure to folic acid and risk of neonatal diabetes/hyperglycemia and type 1 diabetes: A Norwegian register-based study.

Pazzagli L; Karampelias C; Selmer R; Andersson O; Cesta CE
Article: ELIFE. 2021;10:e65758

Insulin-producing β-cells regenerate ectopically from a mesodermal origin under the perturbation of hemato-endothelial specification.

Liu K-C; Villasenor A; Bertuzzi M; Schmitner N; Radros N; Rautio L; Mattonet K; Matsuoka RL; Reischauer S; Stainier DY; Andersson O
Article: NATURE COMMUNICATIONS. 2021;12(1):3362

Reinforcing one-carbon metabolism via folic acid/Folr1 promotes β-cell differentiation.

Karampelias C; Rezanejad H; Rosko M; Duan L; Lu J; Pazzagli L; Bertolino P; Cesta CE; Liu X; Korbutt GS; Andersson O
Article: NATURE METABOLISM. 2021;3(5):682-700

In vivo screen identifies a SIK inhibitor that induces β cell proliferation through a transient UPR.

Charbord J; Ren L; Sharma RB; Johansson A; Ågren R; Chu L; Tworus D; Schulz N; Charbord P; Stewart AF; Wang P; Alonso LC; Andersson O
Article: PLOS GENETICS. 2021;17(3):e1009402

NCK-associated protein 1 like (nckap1l) minor splice variant regulates intrahepatic biliary network morphogenesis.

Ghaffari K; Pierce LX; Roufaeil M; Gibson I; Tae K; Sahoo S; Cantrell JR; Andersson O; Lau J; Sakaguchi TF
Journal article: DIABETES. 2019;68

Pancreatic Elastase Regulates Human Beta-Cell Proliferation via the Focal Adhesion and PAR2 Signaling Pathways

Basile G; Vetere A; Liu K-C; Hu J; Andersson O; Wagner B; Kulkarni R
Article: PLOS GENETICS. 2018;14(2):e1007224

SOX2 regulates common and specific stem cell features in the CNS and endoderm derived organs.

Hagey DW; Klum S; Kurtsdotter I; Zaouter C; Topcic D; Andersson O; Bergsland M; Muhr J
Article: DIABETES. 2018;67(1):58-70

Inhibition of Cdk5 Promotes β-Cell Differentiation From Ductal Progenitors.

Liu K-C; Leuckx G; Sakano D; Seymour PA; Mattsson CL; Rautio L; Staels W; Verdonck Y; Serup P; Kume S; Heimberg H; Andersson O
Article: INTERNATIONAL JOURNAL OF ENDOCRINOLOGY. 2017;2017:1365209-9

Combination Therapy with a Sodium-Glucose Cotransporter 2 Inhibitor and a Dipeptidyl Peptidase-4 Inhibitor Additively Suppresses Macrophage Foam Cell Formation and Atherosclerosis in Diabetic Mice.

Terasaki M; Hiromura M; Mori Y; Kohashi K; Kushima H; Ohara M; Watanabe T; Andersson O; Hirano T
Article: MOLECULAR METABOLISM. 2016;5(11):1138-1146

Critical role for adenosine receptor A2a in β-cell proliferation.

Schulz N; Liu K-C; Charbord J; Mattsson CL; Tao L; Tworus D; Andersson O
Article: EMBO JOURNAL. 2016;35(18):2026-2044

IGFBP1 increases β-cell regeneration by promoting α- to β-cell transdifferentiation.

Lu J; Liu K-C; Schulz N; Karampelias C; Charbord J; Hilding A; Rautio L; Bertolino P; Östenson C-G; Brismar K; Andersson O
Article: NATURE. 2016;535(7611):294-298

Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification.

Reischauer S; Stone OA; Villasenor A; Chi N; Jin S-W; Martin M; Lee MT; Fukuda N; Marass M; Witty A; Fiddes I; Kuo T; Chung W-S; Salek S; Lerrigo R; Alsiö J; Luo S; Tworus D; Augustine SM; Mucenieks S; Nystedt B; Giraldez AJ; Schroth GP; Andersson O; Stainier DYR
Article: GENOME RESEARCH. 2016;26(7):908-917

Distinct transcription factor complexes act on a permissive chromatin landscape to establish regionalized gene expression in CNS stem cells.

Hagey DW; Zaouter C; Combeau G; Lendahl MA; Andersson O; Huss M; Muhr J
Article: SCIENTIFIC REPORTS. 2016;6:24992

sept7b is required for the differentiation of pancreatic endocrine progenitors.

Dash SN; Hakonen E; Ustinov J; Otonkoski T; Andersson O; Lehtonen S
Article: CELL METABOLISM. 2016;23(1):194-205

SerpinB1 Promotes Pancreatic β Cell Proliferation.

El Ouaamari A; Dirice E; Gedeon N; Hu J; Zhou J-Y; Shirakawa J; Hou L; Goodman J; Karampelias C; Qiang G; Boucher J; Martinez R; Gritsenko MA; De Jesus DF; Kahraman S; Bhatt S; Smith RD; Beer H-D; Jungtrakoon P; Gong Y; Goldfine AB; Liew CW; Doria A; Andersson O; Qian W-J; Remold-O'Donnell E; Kulkarni RN
Article: MOLECULAR AND CELLULAR BIOLOGY. 2015;36(5):756-764

ActivinB Is Induced in Insulinoma To Promote Tumor Plasticity through a β-Cell-Induced Dedifferentiation.

Ripoche D; Charbord J; Hennino A; Teinturier R; Bonnavion R; Jaafar R; Goehrig D; Cordier-Bussat M; Ritvos O; Zhang CX; Andersson O; Bertolino P
Article: NATURE CHEMICAL BIOLOGY. 2014;10(2):141-148

VMAT2 identified as a regulator of late-stage β-cell differentiation.

Sakano D; Shiraki N; Kikawa K; Yamazoe T; Kataoka M; Umeda K; Araki K; Mao D; Matsumoto S; Nakagata N; Andersson O; Stainier D; Endo F; Kume K; Uesugi M; Kume S
Article: NATURE CHEMICAL BIOLOGY. 2013;9(2):97-104

Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.

Gut P; Baeza-Raja B; Andersson O; Hasenkamp L; Hsiao J; Hesselson D; Akassoglou K; Verdin E; Hirschey MD; Stainier DYR
Article: CELL METABOLISM. 2012;15(6):885-894

Adenosine signaling promotes regeneration of pancreatic β cells in vivo.

Andersson O; Adams BA; Yoo D; Ellis GC; Gut P; Anderson RM; German MS; Stainier DYR
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(3):1142-1147

Suppression of Alk8-mediated Bmp signaling cell-autonomously induces pancreatic beta-cells in zebrafish.

Chung W-S; Andersson O; Row R; Kimelman D; Stainier DYR
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(20):7252-7256

Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity.

Andersson O; Korach-Andre M; Reissmann E; Ibáñez CF; Bertolino P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(20):7246-7251

Activin B receptor ALK7 is a negative regulator of pancreatic beta-cell function.

Bertolino P; Holmberg R; Reissmann E; Andersson O; Berggren P-O; Ibáñez CF
Article: JOURNAL OF CELL BIOLOGY. 2008;180(3):597-605

Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction.

D'Andrea D; Liguori GL; Le Good JA; Lonardo E; Andersson O; Constam DB; Persico MG; Minchiotti G
Article: DEVELOPMENTAL BIOLOGY. 2007;311(2):500-511

Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development.

Andersson O; Bertolino P; Ibáñez CF
Article: EMBO REPORTS. 2006;7(8):831-837

Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis.

Andersson O; Reissmann E; Ibáñez CF
Article: DEVELOPMENTAL BIOLOGY. 2006;293(2):370-381

Synergistic interaction between Gdf1 and Nodal during anterior axis development.

Andersson O; Reissmann E; Jörnvall H; Ibáñez CF
Article: MOLECULAR AND CELLULAR BIOLOGY. 2004;24(21):9383-9389

ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse.

Jörnvall H; Reissmann E; Andersson O; Mehrkash M; Ibáñez CF
Article: GENES & DEVELOPMENT. 2001;15(15):2010-2022

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development.

Reissmann E; Jörnvall H; Blokzijl A; Andersson O; Chang C; Minchiotti G; Persico MG; Ibáñez CF; Brivanlou AH
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Preprint: BIORXIV. 2024

Characterization of liver-pancreas crosstalk following β-cell loss reveals a role for the molybdenum cofactor in β-cell regeneration

Karampelias C; Băloiu B; Rathkolb B; da Silva-Buttkus P; Bachar-Wikström E; Marschall S; Fuchs H; Durner VG; Chu L; de Angelis MH; Andersson O
Preprint: BIORXIV. 2023

Biodistribution of DNA-origami nanostructures in live zebrafish embryos with single-cell resolution

Kolonelou C; Bräutigam L; Edwards S; Engström E; Dias JM; Spratt J; Karampelias C; Wennmalm S; Brismar H; Andersson O; Teixeira AI
Preprint: BIORXIV. 2023

Inhibition of mammalian mtDNA transcription paradoxically activates liver fatty acid oxidation to reverse diet-induced hepatosteatosis and obesity

Jiang S; Yuan T; Kremer LS; Rosenberger FA; Hansen FM; Borg M; Rubalcava-Gracia D; Mennuni M; Filograna R; Alsina D; Misic J; Koolmeister C; Ren L; Andersson O; Unger A; Bergbrede T; Di Lucrezia R; Wibom R; Zierath JR; Krook A; Giavalisco P; Mann M; Larsson N-G
Preprint: RESEARCH SQUARE. 2023

The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling

Chagin A; Xie M; Tesarova M; Gershtein Y; Schnyder D; Devyatirov R; Gazizova G; Shagimardanova E; Zikmund T; Kerckhofs G; Ivashkin E; Batkovskyte D; Newton P; Andersson O; Fried K; Gusev O; Zeberg H; Kaiser J; Adameyko I
Preprint: BIORXIV. 2022

Efficient knock-in method enabling lineage tracing in zebrafish

Mi J; Andersson O
Preprint: BIORXIV. 2021

Regenerating insulin-producing β-cells ectopically from a mesodermal origin in the absence of endothelial specification

Liu K-C; Villasenor A; Schmitner N; Radros N; Rautio L; Reischauer S; Stainier DYR; Andersson O
Conference publication: DIABETOLOGIA. 2019;62:S73

Pancreatic elastase regulates human beta cell proliferation via the focal adhesion and PAR2 signalling pathways

Basile G; Vetere A; Ijaduola O; Hu J; Liu K-C; Zhang Y; Andersson O; Wagner BK; Kulkarni RN
Review: EXPERIMENTAL CELL RESEARCH. 2014;321(1):3-10

Role of adenosine signalling and metabolism in β-cell regeneration.

Andersson O

Anställningar

Senior Forskare, Cell- och molekylärbiologi, Karolinska Institutet, 2022-

Examina och utbildning

Docent, Molekylär medicin, Karolinska Institutet, 2019
MEDICINE DOKTORSEXAMEN, Institutionen för neurovetenskap, Karolinska Institutet, 2006

Artiklar

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Anställningar

Examina och utbildning

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